Oscar Perez-Leal

Oscar Perez-Leal

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Oscar Perez-Leal

Oscar Perez-Leal

Publications by authors named "Oscar Perez-Leal"

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18Publications

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Pharmacological stimulation of nuclear factor (erythroid-derived 2)-like 2 translation activates antioxidant responses.

J Biol Chem 2017 08 6;292(34):14108-14121. Epub 2017 Jul 6.

From the Department of Pharmaceutical Sciences, Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, Philadelphia, Pennsylvania 19140

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http://dx.doi.org/10.1074/jbc.M116.770925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572918PMC
August 2017

Design, synthesis and SAR of new-di-substituted pyridopyrimidines as ATP-competitive dual PI3Kα/mTOR inhibitors.

Bioorg Med Chem Lett 2017 07 15;27(14):3117-3122. Epub 2017 May 15.

Moulder Center for Drug Discovery Research, Temple University, School of Pharmacy, 3307 N. Broad Street, Philadelphia, PA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X173052
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http://dx.doi.org/10.1016/j.bmcl.2017.05.044DOI Listing
July 2017

A novel assay platform for the detection of translation modulators of spermidine/spermine acetyltransferase.

Curr Pharm Des 2014 ;20(2):245-52

Department of Biochemistry and Fels Institute for Cancer Research, School of Medicine and 2 Moulder Center for Drug Discovery, School of Pharmacy, Temple University 3307 N. Broad Street, Philadelphia, PA 19140.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871977PMC
http://dx.doi.org/10.2174/13816128113199990035DOI Listing
October 2014

Modulation of polyamine metabolic flux in adipose tissue alters the accumulation of body fat by affecting glucose homeostasis.

Amino Acids 2014 Mar 24;46(3):701-15. Epub 2013 Jul 24.

AHB/552, Department of Biochemistry, Temple University School of Medicine, 3307N. Broad Street, Philadelphia, PA, 19140, USA.

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http://dx.doi.org/10.1007/s00726-013-1548-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5184767PMC
March 2014

Translational control of Nrf2 within the open reading frame.

Biochem Biophys Res Commun 2013 Jul 24;437(1):134-9. Epub 2013 Jun 24.

Department of Biochemistry and Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.bbrc.2013.06.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780388PMC
July 2013

Polyamine-regulated translation of spermidine/spermine-N1-acetyltransferase.

Mol Cell Biol 2012 Apr 21;32(8):1453-67. Epub 2012 Feb 21.

Department of Biochemistry, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1128/MCB.06444-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318587PMC
April 2012

Regulation of polyamine metabolism by translational control.

Amino Acids 2012 Feb 3;42(2-3):611-7. Epub 2011 Aug 3.

AHB/552, Department of Biochemistry, Temple University of School of Medicine, 3307 N. Broad Street, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1007/s00726-011-1036-6DOI Listing
February 2012

Pneumocystis S-adenosylmethionine transport: a potential drug target.

Am J Respir Cell Mol Biol 2011 Dec 3;45(6):1142-6. Epub 2011 Jun 3.

Department of Biochemistry, Temple University School of Medicine, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1165/rcmb.2011-0009OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262670PMC
December 2011

Mechanism and tissue specificity of nicotine-mediated lung S-adenosylmethionine reduction.

J Biol Chem 2008 Mar 7;283(12):7690-6. Epub 2008 Jan 7.

Department of Biochemistry, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.

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http://dx.doi.org/10.1074/jbc.M709399200DOI Listing
March 2008

Identifying and characterising the Plasmodium falciparum RhopH3 Plasmodium vivax homologue.

Biochem Biophys Res Commun 2007 Jul 11;358(3):861-6. Epub 2007 May 11.

Molecular Biology Department, Fundacion Instituto de Inmunologia de Colombia, Carrera 50#26-00, Bogota, Colombia.

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http://dx.doi.org/10.1016/j.bbrc.2007.05.015DOI Listing
July 2007

Cloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface protein.

Biochem Biophys Res Commun 2006 Dec 24;351(3):639-44. Epub 2006 Oct 24.

Molecular Biology Department, Fundacion Instituto de Inmunologia de Colombia, Bogota, Colombia.

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http://dx.doi.org/10.1016/j.bbrc.2006.10.082DOI Listing
December 2006

The Plasmodium vivax rhoptry-associated protein 1.

Biochem Biophys Res Commun 2006 Mar 25;341(4):1053-8. Epub 2006 Jan 25.

Molecular Biology Department, Fundacion Instituto de Inmunologia de Colombia, Bogota, Colombia.

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http://dx.doi.org/10.1016/j.bbrc.2006.01.061DOI Listing
March 2006

Identification and characterisation of the Plasmodium vivax rhoptry-associated protein 2.

Biochem Biophys Res Commun 2005 Nov 29;337(3):853-9. Epub 2005 Sep 29.

Molecular Biology Department, Fundacion Instituto de Inmunologia de Colombia, Bogota, Colombia.

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http://dx.doi.org/10.1016/j.bbrc.2005.09.120DOI Listing
November 2005

Identifying and characterising the Plasmodium falciparum merozoite surface protein 10 Plasmodium vivax homologue.

Biochem Biophys Res Commun 2005 Jun;331(4):1178-84

Molecular Biology Department, Fundacion Instituto de Inmunologia de Colombia, Bogota, Colombia.

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http://dx.doi.org/10.1016/j.bbrc.2005.04.031DOI Listing
June 2005

Plasmodium vivax merozoite surface protein 8 cloning, expression, and characterisation.

Biochem Biophys Res Commun 2004 Nov;324(4):1393-9

Molecular Biology Department, Fundacion Instituto de Inmunologia de Colombia, Bogotá, Colombia.

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http://dx.doi.org/10.1016/j.bbrc.2004.09.202DOI Listing
November 2004