Publications by authors named "Omar Rossi"

23Publications

Dissecting the contribution of O-Antigen and proteins to the immunogenicity of Shigella sonnei generalized modules for membrane antigens (GMMA).

Authors:
Francesca Mancini Gianmarco Gasperini Omar Rossi Maria Grazia Aruta Maria Michelina Raso Renzo Alfini Massimiliano Biagini Francesca Necchi Francesca Micoli

Sci Rep 2021 Jan 13;11(1):906. Epub 2021 Jan 13.

GSK Vaccines Institute for Global Health (GVGH), via Fiorentina 1, 53100, Siena, Italy.

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January 2021

Characterization of Competitive ELISA and Formulated Alhydrogel Competitive ELISA (FAcE) for Direct Quantification of Active Ingredients in GMMA-Based Vaccines.

Authors:
Omar Rossi Maria Grazia Aruta Alessandra Acquaviva Francesca Mancini Francesca Micoli Francesca Necchi

Methods Protoc 2020 Aug 31;3(3). Epub 2020 Aug 31.

GSK Vaccines Institute for Global Health s.r.l (GVGH), 53100 Siena, Italy.

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August 2020

Within-host spatiotemporal dynamic of systemic salmonellosis: Ways to track infection, reaction to vaccination and antimicrobial treatment.

Authors:
Omar Rossi Myrto Vlazaki Panchali Kanvatirth Olivier Restif Pietro Mastroeni

J Microbiol Methods 2020 09 21;176:106008. Epub 2020 Jul 21.

University of Cambridge, Department of Veterinary Medicine, Madingley Road, CB3 0ES Cambridge, UK. Electronic address:

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September 2020

Outer membrane vesicles: moving within the intricate labyrinth of assays that can predict risks of reactogenicity in humans.

Authors:
Omar Rossi Francesco Citiulo Francesca Mancini

Hum Vaccin Immunother 2020 Jul 20:1-13. Epub 2020 Jul 20.

GSK Vaccines Institute for Global Health S.r.l (GVGH) , Siena, Italy.

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July 2020

A data-based mathematical modelling study to quantify the effects of ciprofloxacin and ampicillin on the within-host dynamics of during treatment and relapse.

Authors:
Myrto Vlazaki Omar Rossi David J Price Callum McLean Andrew J Grant Pietro Mastroeni Olivier Restif

J R Soc Interface 2020 07 8;17(168):20200299. Epub 2020 Jul 8.

Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK.

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July 2020

Antibodies and Protection in Systemic Infections: Do We Still Have More Questions than Answers?

Authors:
Pietro Mastroeni Omar Rossi

Infect Immun 2020 Sep 18;88(10). Epub 2020 Sep 18.

GSK Vaccines Institute for Global Health, Siena, Italy.

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September 2020

OMV Vaccines and the Role of TLR Agonists in Immune Response.

Authors:
Francesca Mancini Omar Rossi Francesca Necchi Francesca Micoli

Int J Mol Sci 2020 Jun 21;21(12). Epub 2020 Jun 21.

GSK Vaccines Institute for Global Health s.r.l (GVGH), 53100 Siena, Italy.

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June 2020

Intra-Laboratory Evaluation of Luminescence Based High-Throughput Serum Bactericidal Assay (L-SBA) to Determine Bactericidal Activity of Human Sera against .

Authors:
Omar Rossi Eleonora Molesti Allan Saul Carlo Giannelli Francesca Micoli Francesca Necchi

High Throughput 2020 Jun 8;9(2). Epub 2020 Jun 8.

GSK Vaccines Institute for Global Health s.r.l (GVGH), Siena 53100, Italy.

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June 2020

Development of FAcE (Formulated Alhydrogel competitive ELISA) method for direct quantification of OAg present in Shigella sonnei GMMA-based vaccine and its optimization using Design of Experiments approach.

Authors:
Francesca Necchi Martina Carducci Ivan Pisoni Omar Rossi Allan Saul Simona Rondini

J Immunol Methods 2019 08 27;471:11-17. Epub 2019 Apr 27.

GSK Vaccines Institute for Global Health (GVGH) S.r.l., Siena, Italy. Electronic address:

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August 2019

Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal .

Authors:
Francesca Micoli Simona Rondini Renzo Alfini Luisa Lanzilao Francesca Necchi Aurel Negrea Omar Rossi Cornelia Brandt Simon Clare Pietro Mastroeni Rino Rappuoli Allan Saul Calman A MacLennan

Proc Natl Acad Sci U S A 2018 10 27;115(41):10428-10433. Epub 2018 Sep 27.

Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom.

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October 2018

The essential role of complement in antibody-mediated resistance to Salmonella.

Authors:
Omar Rossi Chris Coward Yun Shan Goh Jill W C Claassens Calman A MacLennan Sjef J Verbeek Pietro Mastroeni

Immunology 2019 01 10;156(1):69-73. Epub 2018 Oct 10.

Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.

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January 2019

Contribution of factor H-Binding protein sequence to the cross-reactivity of meningococcal native outer membrane vesicle vaccines with over-expressed fHbp variant group 1.

Authors:
Arianna Marini Omar Rossi Maria Grazia Aruta Francesca Micoli Simona Rondini Serafina Guadagnuolo Isabel Delany Ian R Henderson Adam F Cunningham Allan Saul Calman A MacLennan Oliver Koeberling

PLoS One 2017 25;12(7):e0181508. Epub 2017 Jul 25.

GSK Vaccines Institute for Global Health (GVGH), Siena, Italy.

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October 2017

Effect of in vivo neutralization of tumor necrosis alpha on the efficacy of antibiotic treatment in systemic Salmonella enterica infections.

Authors:
Omar Rossi Andrew J Grant Pietro Mastroeni

Pathog Dis 2017 01;75(1)

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January 2017

Immunology, epidemiology and mathematical modelling towards a better understanding of invasive non-typhoidal Salmonella disease and rational vaccination approaches.

Authors:
Pietro Mastroeni Omar Rossi

Expert Rev Vaccines 2016 12 27;15(12):1545-1555. Epub 2016 May 27.

a Department of Veterinary Medicine , University of Cambridge , Cambridge , United Kingdom.

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December 2016

Toll-Like Receptor Activation by Generalized Modules for Membrane Antigens from Lipid A Mutants of Salmonella enterica Serovars Typhimurium and Enteritidis.

Authors:
Omar Rossi Mariaelena Caboni Aurel Negrea Francesca Necchi Renzo Alfini Francesca Micoli Allan Saul Calman A MacLennan Simona Rondini Christiane Gerke

Clin Vaccine Immunol 2016 Apr 4;23(4):304-14. Epub 2016 Apr 4.

Novartis Vaccines Institute for Global Health, S.r.l., Siena, Italy

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April 2016

Quantitative proteomic analysis of Shigella flexneri and Shigella sonnei Generalized Modules for Membrane Antigens (GMMA) reveals highly pure preparations.

Authors:
Luana Maggiore Lu Yu Ulrich Omasits Omar Rossi Gordon Dougan Nicholas R Thomson Allan Saul Jyoti S Choudhary Christiane Gerke

Int J Med Microbiol 2016 Feb 23;306(2):99-108. Epub 2015 Dec 23.

Novartis Vaccines Institute for Global Health, Via Fiorentina 1, 53100 Siena, Italy.

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February 2016

Production of a Shigella sonnei Vaccine Based on Generalized Modules for Membrane Antigens (GMMA), 1790GAHB.

Authors:
Christiane Gerke Anna Maria Colucci Carlo Giannelli Silvia Sanzone Claudia Giorgina Vitali Luigi Sollai Omar Rossi Laura B Martin Jochen Auerbach Vito Di Cioccio Allan Saul

PLoS One 2015 6;10(8):e0134478. Epub 2015 Aug 6.

Sclavo Behring Vaccines Institute for Global Health S.r.l., Siena, Italy.

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May 2016

Draft genomes of Shigella strains used by the STOPENTERICS consortium.

Authors:
Omar Rossi Kate S Baker Armelle Phalipon François-Xavier Weill Francesco Citiulo Philippe Sansonetti Christiane Gerke Nicholas R Thomson

Gut Pathog 2015 4;7:14. Epub 2015 Jun 4.

Wellcome Trust Sanger Institute, Hinxton, UK.

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June 2015

An O antigen capsule modulates bacterial pathogenesis in Shigella sonnei.

Authors:
Mariaelena Caboni Thierry Pédron Omar Rossi David Goulding Derek Pickard Francesco Citiulo Calman A MacLennan Gordon Dougan Nicholas R Thomson Allan Saul Philippe J Sansonetti Christiane Gerke

PLoS Pathog 2015 Mar 20;11(3):e1004749. Epub 2015 Mar 20.

Novartis Vaccines Institute for Global Health, Siena, Via Fiorentina, Italy.

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March 2015

Comparison of colorimetric assays with quantitative amino acid analysis for protein quantification of Generalized Modules for Membrane Antigens (GMMA).

Authors:
Omar Rossi Luana Maggiore Francesca Necchi Oliver Koeberling Calman A MacLennan Allan Saul Christiane Gerke

Mol Biotechnol 2015 Jan;57(1):84-93

Novartis Vaccines Institute for Global Health, Via Fiorentina 1, 53100, Siena, Italy.

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January 2015

Modulation of endotoxicity of Shigella generalized modules for membrane antigens (GMMA) by genetic lipid A modifications: relative activation of TLR4 and TLR2 pathways in different mutants.

Authors:
Omar Rossi Isabella Pesce Carlo Giannelli Susanna Aprea Mariaelena Caboni Francesco Citiulo Sara Valentini Ilaria Ferlenghi Calman Alexander MacLennan Ugo D'Oro Allan Saul Christiane Gerke

J Biol Chem 2014 Sep 14;289(36):24922-35. Epub 2014 Jul 14.

From the Novartis Vaccines Institute for Global Health and

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September 2014

A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on generalized modules for membrane antigens (GMMA).

Authors:
Oliver Koeberling Emma Ispasanie Julia Hauser Omar Rossi Gerd Pluschke Dominique A Caugant Allan Saul Calman A MacLennan

Vaccine 2014 May 3;32(23):2688-95. Epub 2014 Apr 3.

Novartis Vaccines Institute for Global Health, Siena, Italy; University of Birmingham, Birmingham, United Kingdom. Electronic address:

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May 2014

High yield production process for Shigella outer membrane particles.

Authors:
Francesco Berlanda Scorza Anna Maria Colucci Luana Maggiore Silvia Sanzone Omar Rossi Ilaria Ferlenghi Isabella Pesce Mariaelena Caboni Nathalie Norais Vito Di Cioccio Allan Saul Christiane Gerke

PLoS One 2012 6;7(6):e35616. Epub 2012 Jun 6.

Novartis Vaccines Institute for Global Health, Siena, Italy.

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November 2012