Omar L Francone

Omar L Francone

UNVERIFIED PROFILE

Are you Omar L Francone?   Register this Author

Register author
Omar L Francone

Omar L Francone

Publications by authors named "Omar L Francone"

Are you Omar L Francone?   Register this Author

28Publications

279Reads

49Profile Views

Silencing of enzymes involved in ceramide biosynthesis causes distinct global alterations of lipid homeostasis and gene expression.

J Lipid Res 2012 Aug 23;53(8):1459-71. Epub 2012 May 23.

Department of Cardiovascular, Metabolic, and Endocrine Diseases, Pfizer Inc., Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M020941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540863PMC
August 2012

The PPARα agonists fenofibrate and CP-778875 cause increased β-oxidation, leading to oxidative injury in skeletal and cardiac muscle in the rat.

Toxicol Pathol 2012 Apr 1;40(3):435-47. Epub 2012 Feb 1.

Pfizer Worldwide Research and Development, Groton Laboratory, Pfizer, Inc., Groton, Connecticut 06340, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0192623311431945DOI Listing
April 2012

Adrenal cell aldosterone production is stimulated by very-low-density lipoprotein (VLDL).

Endocrinology 2012 Feb 20;153(2):721-31. Epub 2011 Dec 20.

Department of Physiology, Georgia Health Sciences University, 1120 15th Street, Augusta, Georgia 30912, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2011-1752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275386PMC
February 2012

A selective peroxisome proliferator-activated receptor alpha agonist, CP-900691, improves plasma lipids, lipoproteins, and glycemic control in diabetic monkeys.

J Pharmacol Exp Ther 2010 Jun 26;333(3):844-53. Epub 2010 Feb 26.

Department of Pathology, Wake Forest University, Winston-Salem, North Carolina 27157, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/jpet.110.166736DOI Listing
June 2010

Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1.

J Lipid Res 2009 Jul 23;50(7):1330-9. Epub 2009 Feb 23.

Pfizer Global Research and Development, Department of Cardiovascular and Metabolic Diseases, Groton, CT 06340, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M900034-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694332PMC
July 2009

The hydrophobic tunnel present in LOX-1 is essential for oxidized LDL recognition and binding.

J Lipid Res 2009 Mar 9;50(3):546-55. Epub 2008 Oct 9.

Department of Atherosclerosis Biology, Pfizer Global Research and Development, Groton, CT 06340, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M800474-JLR200DOI Listing
March 2009

Differential regulation of the cynomolgus, human, and rat acyl-CoA oxidase promoters by PPARalpha.

Gene 2006 Oct 26;380(2):84-94. Epub 2006 May 26.

Pfizer Global Research & Development, Department of Cardiovascular, Metabolic & Endocrine Diseases, MS8220-3201, Groton, Connecticut, 06340, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gene.2006.05.011DOI Listing
October 2006

Pulmonary abnormalities due to ABCA1 deficiency in mice.

Am J Physiol Lung Cell Mol Physiol 2005 Dec 29;289(6):L980-9. Epub 2005 Jul 29.

Institute for Environmental Medicine, 1 John Morgan Bldg., 3620 Hamilton Walk, University of Pennsylvania, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajplung.00234.2005DOI Listing
December 2005

Increased cholesterol deposition, expression of scavenger receptors, and response to chemotactic factors in Abca1-deficient macrophages.

Arterioscler Thromb Vasc Biol 2005 Jun 14;25(6):1198-205. Epub 2005 Apr 14.

Pfizer Global Research and Development, Department of Cardiovascular and Metabolic Diseases, Groton, CT 06340.

View Article

Download full-text PDF

Source
http://atvb.ahajournals.org/content/25/6/1198.full.pdf
Web Search
http://atvb.ahajournals.org/cgi/doi/10.1161/01.ATV.000016652
Publisher Site
http://dx.doi.org/10.1161/01.ATV.0000166522.69552.99DOI Listing
June 2005

ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation.

Cell Metab 2005 Feb;1(2):121-31

Department of Biological Chemistry, CHS 33-257, David Geffen School of Medicine, University of California Los Angeles, 10833 Le Conte Avenue, Los Angeles, California 90095, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S155041310500029
Publisher Site
http://dx.doi.org/10.1016/j.cmet.2005.01.002DOI Listing
February 2005

Identification and characterization of rodent ABCA1 in isolated type II pneumocytes.

Am J Physiol Lung Cell Mol Physiol 2003 Oct 8;285(4):L869-78. Epub 2003 Aug 8.

Institute for Environmental Medicine, University of Pennsylvania, 1 John Morgan Bldg., 36th and Hamilton Walk, Philadelphia, PA 19104-6068, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajplung.00077.2003DOI Listing
October 2003

SR-BI: a new player in an old game.

Authors:
Omar L Francone

Arterioscler Thromb Vasc Biol 2003 Sep;23(9):1486-7

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.ATV.0000091271.12117.ABDOI Listing
September 2003

Abnormal phospholipid composition impairs HDL biogenesis and maturation in mice lacking Abca1.

Biochemistry 2003 Jul;42(28):8569-78

Pfizer Global Research and Development, Groton, Connecticut 06340, USA.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/abs/10.1021/bi034540v
Publisher Site
http://dx.doi.org/10.1021/bi034540vDOI Listing
July 2003

ABCA1-deficient mice: insights into the role of monocyte lipid efflux in HDL formation and inflammation.

Arterioscler Thromb Vasc Biol 2003 Jun 9;23(6):972-80. Epub 2003 Jan 9.

Pfizer Global Research and Development, Department of Cardiovascular and Metabolic Diseases, Eastern Point Road, Groton, Conn 06340, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.ATV.0000054661.21499.FBDOI Listing
June 2003

Increased atherosclerosis in hyperlipidemic mice with inactivation of ABCA1 in macrophages.

Arterioscler Thromb Vasc Biol 2002 Apr;22(4):630-7

Pfizer Global Research and Development, Groton, Connecticut, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.atv.0000014804.35824.daDOI Listing
April 2002

ABCA1: regulation, function and relationship to atherosclerosis.

Curr Opin Investig Drugs 2002 Mar;3(3):415-9

Pfizer Global Research and Development, Groton, CT 06340, USA.

View Article

Download full-text PDF

Source
March 2002