Olivier Vittecoq

Olivier Vittecoq

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Olivier Vittecoq

Publications by authors named "Olivier Vittecoq"

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Does iron deficiency contribute to fatigue in patients with rheumatoid arthritis without anemia?

Joint Bone Spine 2019 Jun 18. Epub 2019 Jun 18.

Department of Rheumatology, Rouen University Hospital, 76000 Rouen, France.

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http://dx.doi.org/10.1016/j.jbspin.2019.06.004DOI Listing
June 2019

Prealbumin, platelet factor 4 and S100A12 combination at baseline predicts good response to TNF alpha inhibitors in rheumatoid arthritis.

Joint Bone Spine 2019 03 6;86(2):195-201. Epub 2018 Jun 6.

EA 7408, University Grenoble Alpes, GREPI, 38400 Saint-Martin-d'Hères, France; Rheumatology Department, centre hospitalier universitaire Grenoble Alpes, hôpital Sud Echirolles, 38130 Echirolles, France.

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http://dx.doi.org/10.1016/j.jbspin.2018.05.006DOI Listing
March 2019

Predictors of treatment response in rheumatoid arthritis.

Joint Bone Spine 2019 03 4;86(2):151-158. Epub 2018 Jul 4.

Inserm U 1234, Normandie université, UNIROUEN, 76031 Rouen, France; Service de rhumatologie, CHU de Rouen, 76031 Rouen, France.

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http://dx.doi.org/10.1016/j.jbspin.2018.03.018DOI Listing
March 2019

Impact of ACR 2010 fibromyalgia criteria fulfillment on disease activity evaluation in patients with axial spondyloarthritis treated with infliximab.

Joint Bone Spine 2019 01 20;86(1):113-114. Epub 2018 Apr 20.

Department of rheumatology, Rouen University Hospital Charles-Nicolle, CHU de Rouen, 1, rue de Germont, 76000 Rouen, France; Inserm U905, CIC/CRB 1404, 76000 Rouen, France; Department of rheumatology, Elbeuf-Louviers-Val-de-Reuil Hospital, 76503 Saint-Aubin-lès-Elbeuf, France.

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http://dx.doi.org/10.1016/j.jbspin.2018.04.001DOI Listing
January 2019

Effectiveness of vedolizumab for Crohn's disease with spondyloarthritis in fail with two TNF blocking agents.

Joint Bone Spine 2018 07 11;85(4):495-496. Epub 2017 Jul 11.

Service de rhumatologie, CHU-hôpitaux de Rouen, 1, rue de Germont, 76000 Rouen, France.

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http://dx.doi.org/10.1016/j.jbspin.2017.06.006DOI Listing
July 2018

The impact of smoking on rheumatoid arthritis outcomes.

Joint Bone Spine 2018 03 12;85(2):135-138. Epub 2017 Dec 12.

Service de rhumatologie, CHU de Rouen, 1, rue de Germont, 76031 Rouen cedex, France; Université de Rouen, 76000 Rouen, France.

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http://dx.doi.org/10.1016/j.jbspin.2017.12.004DOI Listing
March 2018

Soluble vascular endothelial (VE) cadherin and autoantibodies to VE-cadherin in rheumatoid arthritis patients treated with etanercept or adalimumab.

Joint Bone Spine 2017 Dec 25;84(6):685-691. Epub 2016 Nov 25.

Inserm, Unit 1036, Biology of Cancer and Infection, 38054 Grenoble, France; UJF-Grenoble 1, Biology of Cancer and Infection, 38054 Grenoble, France; CEA Comission at Atomic Energy and Alternative Energies, DRF/B(2)IG direction de la recherche fondamentale/BioScience and Biotechnology Institute of Grenoble, 38054 Grenoble, France.

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http://dx.doi.org/10.1016/j.jbspin.2016.10.012DOI Listing
December 2017

Rheumatoid arthritis, insulin resistance, and diabetes.

Joint Bone Spine 2017 Jul 21;84(4):411-416. Epub 2016 Oct 21.

Service de rhumatologie, Inserm 905, institut de recherche et d'innovation biomédicales, CIC/CRB1404, université de Rouen, hôpitaux de Rouen, CHU, 76031 Rouen cedex, France.

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http://dx.doi.org/10.1016/j.jbspin.2016.09.001DOI Listing
July 2017

Atlantooccipital arthritis inaugurating axial spondyloarthritis.

Joint Bone Spine 2016 Dec 14;83(6):751-752. Epub 2016 Mar 14.

CHU de Rouen, Hôpitaux de Rouen, Inserm U905, CRB CIC 1404, service de rhumatologie, 147, rue du Maréchal-Juin, 76230 Bois-Guillaume, France; Université de Rouen, Institute for Research and Innovation in Biomedicine (IRIB), 76031 Rouen, France. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2016.02.007DOI Listing
December 2016

Shrinking lung syndrome associated with systemic lupus erythematosus: A multicenter collaborative study of 15 new cases and a review of the 155 cases in the literature focusing on treatment response and long-term outcomes.

Autoimmun Rev 2016 Oct 29;15(10):994-1000. Epub 2016 Jul 29.

AP-HP, Service de Médecine Interne 2, Centre National de Référence du Lupus Systémique, Syndrome des Anticorps Anti-phospholipides et Maladies Auto-immunes Systémiques Rares, Groupe Hospitalier Pitié Salpêtrière, Paris 75013, France; Université Paris VI Pierre et Marie Curie, Sorbonnes Universités, Paris 75013, France.

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http://dx.doi.org/10.1016/j.autrev.2016.07.021DOI Listing
October 2016

Identification of 7 Proteins in Sera of RA Patients with Potential to Predict ETA/MTX Treatment Response.

Theranostics 2015 9;5(11):1214-24. Epub 2015 Aug 9.

2. CNRS, UMR6270, Mont Saint Aignan, France ; 3. PISSARO Proteomic Platform, Mont Saint Aignan, France ; 4. Normandy University, IRIB, Rouen, France.

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http://dx.doi.org/10.7150/thno.12403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568449PMC
June 2016

Prophylactic Injection of Recombinant Alpha-Enolase Reduces Arthritis Severity in the Collagen-Induced Arthritis Mice Model.

PLoS One 2015 24;10(8):e0136359. Epub 2015 Aug 24.

INSERM, U905, Rouen, France; Normandy University, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France; Rouen University Hospital, Department of Rheumatology, Rouen, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0136359PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547710PMC
May 2016

Blood and salivary-gland BAFF-driven B-cell hyperactivity is associated to rituximab inefficacy in primary Sjögren's syndrome.

J Autoimmun 2016 Feb 10;67:102-110. Epub 2015 Dec 10.

EA2216, INSERM ESPRI, ERI29, Laboratoire d'Immunothérapies et Pathologies lymphocytaires B, Université de Brest, and Labex "IGO", Brest, France. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2015.11.002DOI Listing
February 2016

Occurrence of Sweet syndrome under anti-TNF.

Clin Rheumatol 2015 Nov 21;34(11):1993-4. Epub 2015 Aug 21.

Department of Rheumatology, CHU de Rouen, Hôpitaux de Rouen, Inserm U905, University of Rouen, 147 avenue du Maréchal Juin, 76230, Bois-Guillaume, Rouen, France.

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http://dx.doi.org/10.1007/s10067-015-3054-3DOI Listing
November 2015

Identification of S100A9 as biomarker of responsiveness to the methotrexate/etanercept combination in rheumatoid arthritis using a proteomic approach.

PLoS One 2014 29;9(12):e115800. Epub 2014 Dec 29.

INSERM, U905, Pathophysiology and Biotherapy of Inflammatory and Autoimmune Diseases, F-76000 Rouen, France; Normandy University, Institute of Research and Innovation in Biomedecine, F-76821 Mont Saint Aignan, France; Department of Rheumatology, Rouen University Hospital, F-76000 Rouen, France; INSERM, Centre d'investigation clinique 1404, F-76000 Rouen, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115800PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278766PMC
October 2015

Switching from an anti-TNF monoclonal antibody to soluble TNF-receptor yields better results than vice versa: An observational retrospective study of 72 rheumatoid arthritis switchers.

Joint Bone Spine 2015 Oct 10;82(5):330-7. Epub 2015 Apr 10.

Rheumatology department, Rouen university hospital, Inserm unit 905, institute for research and innovation in biomedicine, university of Rouen, CIC/CRB 1404, 76031 Rouen cedex, France.

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http://dx.doi.org/10.1016/j.jbspin.2015.01.021DOI Listing
October 2015

Reply to the comment of Brinster et al. "Acquired hemophilia, rheumatoid arthritis, and TNFα antagonists".

Joint Bone Spine 2015 Oct 7;82(5):385-6. Epub 2015 Jul 7.

Inserm U1096, IRIB, service de médecine interne, CHU-Hôpitaux de Rouen, université de Rouen, 76031 Rouen cedex, France.

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http://dx.doi.org/10.1016/j.jbspin.2015.05.003DOI Listing
October 2015

Aiming for SDAI remission versus low disease activity at 1 year after inclusion in ESPOIR cohort is associated with better 3-year structural outcomes.

Ann Rheum Dis 2015 Sep 2;74(9):1676-83. Epub 2014 May 2.

UMR 1027, INSERM, Toulouse, France UMR 1027, University Paul Sabatier Toulouse III, Toulouse, France Rheumatology Center, Purpan Hospital, Toulouse, France.

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2013-20490
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http://dx.doi.org/10.1136/annrheumdis-2013-204906DOI Listing
September 2015

Osteoprotegerin and tumor necrosis factor-related apoptosis-inducing ligand as prognostic factors in rheumatoid arthritis: results from the ESPOIR cohort.

Arthritis Res Ther 2015 Jul 29;17:193. Epub 2015 Jul 29.

Department of Rheumatology, Lapeyronie Hospital, Montpellier University, 371 avenue doyen Giraud, 34295, Montpellier, France.

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http://dx.doi.org/10.1186/s13075-015-0705-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518710PMC
July 2015

Reliability of histopathological salivary gland biopsy assessment in Sjögren's syndrome: a multicentre cohort study.

Rheumatology (Oxford) 2015 Jun 27;54(6):1056-64. Epub 2014 Nov 27.

Pathology Department, Brest University Hospital, Brest, France, Pathology Department, Vannes General Hospital, Vannes, Brest Occidental University, Rheumatology Unit, Hôpital de la Cavale Blanche, EA 2216, ESPRI 29, Brest University, Brest, Rheumatology Department, Hôtel Dieu University Hospital, Nantes, Department of Internal Medicine, Nord-de-France University, Claude-Huriez Hospital, Lille, Rheumatology Department, Rouen University Hospital, Rouen and Brest Occidental University, Clinical Investigation Centre, Institut National de la Santé et de la Recherche Médicale, Brest, France Pathology Department, Brest University Hospital, Brest, France, Pathology Department, Vannes General Hospital, Vannes, Brest Occidental University, Rheumatology Unit, Hôpital de la Cavale Blanche, EA 2216, ESPRI 29, Brest University, Brest, Rheumatology Department, Hôtel Dieu University Hospital, Nantes, Department of Internal Medicine, Nord-de-France University, Claude-Huriez Hospital, Lille, Rheumatology Department, Rouen University Hospital, Rouen and Brest Occidental University, Clinical Investigation Centre, Institut National de la Santé et de la Recherche Médicale, Brest, France

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http://dx.doi.org/10.1093/rheumatology/keu453DOI Listing
June 2015

Acquired hemophilia possibly induced by etanercept in a patient with rheumatoid arthritis.

Joint Bone Spine 2015 May 20;82(3):200-2. Epub 2015 Jan 20.

Service de rhumatologie, CHU-Hôpitaux de Rouen, Inserm U905, CRB CIC 1404, IRIB, Université de Rouen, 76031 Rouen Cedex, France.

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http://dx.doi.org/10.1016/j.jbspin.2014.12.003DOI Listing
May 2015

Pharmacokinetics and concentration-effect relationship of adalimumab in rheumatoid arthritis.

Br J Clin Pharmacol 2015 Feb;79(2):286-97

CNRS, UMR 7292, 'Genetics, Immunotherapy, Chemistry and Cancer', Université François Rabelais de Tours, Tours, France; Laboratoire de pharmacologie-toxicologie, CHRU de Tours, Tours, France.

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http://dx.doi.org/10.1111/bcp.12509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309634PMC
February 2015

Arthritis due to metastasis.

Joint Bone Spine 2015 Jan 22;82(1):66-7. Epub 2014 Sep 22.

Rhumatologie & Inserm, U905 (I.R.I.B.) CIC 1404, CHU Hôpitaux de Rouen, 1, rue de Germont, 76031 Rouen cedex 1, France.

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http://dx.doi.org/10.1016/j.jbspin.2014.07.004DOI Listing
January 2015

[Endothelial junctions: exploiting their instability in the development of biomarkers for vascular remodelling].

Med Sci (Paris) 2014 Jun-Jul;30(6-7):633-5. Epub 2014 Jul 11.

Inserm, Unité 1036, biologie du cancer et de l'infection, 17, rue des Martyrs, 38054 Grenoble Cedex 9, France - UJF-Grenoble 1, biologie du cancer et de l'infection, Grenoble, F-38041, France - CEA, DSV/iRTSV, biologie du cancer et de l'infection, Grenoble, F-38054, France.

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http://dx.doi.org/10.1051/medsci/20143006012DOI Listing
September 2014

Towards an individualised target concentration of adalimumab in rheumatoid arthritis.

Ann Rheum Dis 2014 Jul 18;73(7):1428-9. Epub 2014 Feb 18.

Université François-Rabelais de Tours, CNRS, UMR 7292, Tours, France Service de Rhumatologie, CHRU de Tours, Tours, France.

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2013-20497
Publisher Site
http://dx.doi.org/10.1136/annrheumdis-2013-204971DOI Listing
July 2014

Reactive macrophage activation syndrome possibly triggered by canakinumab in a patient with adult-onset Still's disease.

Joint Bone Spine 2013 Dec 7;80(6):653-5. Epub 2013 Jun 7.

Service de Rhumatologie, Inserm U905, CIC-CRB0204, Institute for Research and Innovation in Biomedicine (IRIB), CHU-Hôpitaux de Rouen, Université de Rouen, 76031 Rouen cedex, France. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2013.04.011DOI Listing
December 2013

No impact of tumor necrosis-factor antagonists on the joint manifestations of sarcoidosis.

Int J Gen Med 2013 22;6:605-11. Epub 2013 Jul 22.

Rheumatology Department, Rouen University Hospital, Rouen, France.

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http://dx.doi.org/10.2147/IJGM.S44542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724565PMC
July 2013

Outcome of anti-PL12 positive patients with antisynthetase syndrome.

Presse Med 2013 Jun 18;42(6 Pt 1):e153-8. Epub 2013 Feb 18.

CHU Rouen, Institute for Biochemical Research, University of Rouen IFRMP, Department of Internal medicine, Inserm U 905, 76031 Rouen cedex, France.

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http://dx.doi.org/10.1016/j.lpm.2012.12.003DOI Listing
June 2013

Efficacy of anti-TNF in patients with spondyloarthritis in absence of any imaging sign.

Joint Bone Spine 2013 May 26;80(3):280-6. Epub 2012 Sep 26.

Service de rhumatologie, CHU-hôpitaux de Rouen, hôpital de Bois-Guillaume, 147, avenue du Maréchal-Juin, 76230 Bois-Guillaume, France.

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http://dx.doi.org/10.1016/j.jbspin.2012.08.003DOI Listing
May 2013

Role for magnetic resonance imaging in coccydynia with sacrococcygeal dislocation.

Joint Bone Spine 2013 Mar 23;80(2):214-6. Epub 2012 Oct 23.

Service de Rhumatologie, CHU-hôpitaux de Rouen, 1, rue de Germont, 76031 Rouen cedex, France.

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http://dx.doi.org/10.1016/j.jbspin.2012.09.006DOI Listing
March 2013

[Goals of therapy in rheumatoid arthritis].

Rev Prat 2012 Oct;62(8):1094-8

Service de rhumatologie, CHU-hôpitaux de Rouen, 76031 Rouen Cedex, France.

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October 2012

Number and phenotype of rheumatoid arthritis patients' CD4+CD25hi regulatory T cells are not affected by adalimumab or etanercept.

Rheumatology (Oxford) 2011 Oct 26;50(10):1814-22. Epub 2011 Jul 26.

Inserm, U905, Institut Fédératif de Recherche Multidisciplinaire surles Peptides 23, Institute for Biomedical Research, University of Rouen, Faculté de Médecine-Pharmacie, Rouen, France.

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http://dx.doi.org/10.1093/rheumatology/ker183DOI Listing
October 2011

AL amyloidosis with myeloma mimicking rheumatoid arthritis.

Joint Bone Spine 2011 Mar 9;78(2):215-6. Epub 2010 Dec 9.

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http://dx.doi.org/10.1016/j.jbspin.2010.10.007DOI Listing
March 2011

Early and long-standing rheumatoid arthritis: distinct molecular signatures identified by gene-expression profiling in synovia.

Arthritis Res Ther 2009 29;11(3):R99. Epub 2009 Jun 29.

Department of Rheumatology, Rouen University Hospital and Inserm 905 & Institut Fédératif de Recherche Multidisciplinaire sur les Peptides 23, Institute for Biomedical Research, University of Rouen, 76031 Rouen Cedex, France.

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http://dx.doi.org/10.1186/ar2744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714155PMC
March 2010

Binding immunoglobulin protein-treated peripheral blood monocyte-derived dendritic cells are refractory to maturation and induce regulatory T-cell development.

Immunology 2009 Oct;128(2):218-26

Department of Academic Rheumatology, King's College London School of Medicine at Guy's, King's and St Thomas' Hospitals, Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1111/j.1365-2567.2009.03103.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767311PMC
October 2009

Candidate autoantigens identified by mass spectrometry in early rheumatoid arthritis are chaperones and citrullinated glycolytic enzymes.

Arthritis Res Ther 2009 10;11(2):R38. Epub 2009 Mar 10.

Department of Rheumatology and Inserm Unit 905, IFRMP 23, Institute for Biomedical Research, University of Rouen, Rouen University Hospital, Rouen 76031 cedex, France.

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http://dx.doi.org/10.1186/ar2644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688184PMC
July 2009

Paradoxical adverse events of anti-tumour necrosis factor therapy for spondyloarthropathies: a retrospective study.

Rheumatology (Oxford) 2009 Jul 24;48(7):761-4. Epub 2009 Apr 24.

Department of Pharmacy, University of Medicine-Pharmacy, Rouen University Hospital and Inserm U905 (IFRMP 23), Institute for Biomedical Research, University of Rouen, Rouen,France.

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http://dx.doi.org/10.1093/rheumatology/kep083DOI Listing
July 2009

Diagnostic and prognostic usefulness of antibodies to citrullinated peptides.

Joint Bone Spine 2009 Jul 12;76(4):343-9. Epub 2009 Jun 12.

Service de Rhumatologie, Institut de Recherche Biomédicale, CHU-Hôpitaux de Rouen, France.

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http://dx.doi.org/10.1016/j.jbspin.2008.12.006DOI Listing
July 2009

Atypical forms of syphilis: two cases.

Joint Bone Spine 2009 May 16;76(3):293-5. Epub 2009 Mar 16.

Service de Rhumatologie, CHU-Hôpitaux de Rouen, & Inserm, U905, IFRMP23, Institut de Biologie Clinique, Rouen, France.

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http://dx.doi.org/10.1016/j.jbspin.2008.10.012DOI Listing
May 2009

[Anti-TNF alpha in the treatment of rheumatoid arthritis and ankylosing spondylitis].

Presse Med 2009 May 26;38(5):774-87. Epub 2009 Mar 26.

Service de rhumatologie, CHU de Rouen-Hôpitaux de Rouen, Inserm 905, F-76031 Rouen Cedex, France.

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http://dx.doi.org/10.1016/j.lpm.2009.02.003DOI Listing
May 2009

Post-partum sacral fracture associated with heparin treatment.

Clin Rheumatol 2008 Dec 6;27 Suppl 2:S51-3. Epub 2008 May 6.

Department of Rheumatology, Rouen University Hospital & Inserm U905 (IFRMP 23), Institute for Biomedical Research, University of Rouen, 76031 Rouen cedex, France.

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http://dx.doi.org/10.1007/s10067-008-0898-9DOI Listing
December 2008

Smoking and inflammatory diseases.

Best Pract Res Clin Rheumatol 2008 Oct;22(5):923-35

Department of Rheumatology, Rouen University Hospital & Inserm U905, Rouen, France.

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http://dx.doi.org/10.1016/j.berh.2008.09.011DOI Listing
October 2008

What is the role for interleukin-1 receptor antagonist in rheumatic disease?

Joint Bone Spine 2007 May 22;74(3):223-6. Epub 2007 Feb 22.

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http://dx.doi.org/10.1016/j.jbspin.2006.10.006DOI Listing
May 2007

Recommendations of the French Society for Rheumatology. TNFalpha antagonist therapy in rheumatoid arthritis.

Joint Bone Spine 2006 Jul 5;73(4):433-41. Epub 2006 Jun 5.

Service de Rhumatologie, Groupe Hospitalier Pitié-Salpêtrière, UFR de Médecine, Université Pierre et Marie-Curie-Paris-VI, 83, Boulevard de l'Hôpital, 75651 Paris cedex 13, France.

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http://dx.doi.org/10.1016/j.jbspin.2006.04.001DOI Listing
July 2006

The preclinical phase of rheumatoid arthritis and lupus.

Joint Bone Spine 2005 Dec 6;72(6):443-6. Epub 2005 Jun 6.

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http://dx.doi.org/10.1016/j.jbspin.2005.01.008DOI Listing
December 2005

[Proteomics and autoantibody].

Med Sci (Paris) 2005 Aug-Sep;21(8-9):759-64

INSERM U.519, Faculté de médecine-pharmacie, 22 boulevard Gambetta, 76183 Rouen Cedex, France.

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http://dx.doi.org/10.1051/medsci/2005218-9759DOI Listing
December 2005

Foot orthotics decrease pain but do not improve gait in rheumatoid arthritis patients.

Joint Bone Spine 2004 Nov;71(6):542-5

Department of Rheumatology, CHU de Rouen, Centre Hospitalier Universitaire, 76031 Rouen, France.

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http://dx.doi.org/10.1016/j.jbspin.2003.09.007DOI Listing
November 2004

Cerivastatin-induced polymyalgia rheumatica-like illness.

Clin Rheumatol 2004 Apr 24;23(2):179. Epub 2004 Jan 24.

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http://dx.doi.org/10.1007/s10067-003-0772-8DOI Listing
April 2004

A new tool for rheumatology: large-scale analysis of gene expression.

Joint Bone Spine 2003 Aug;70(4):248-56

Rheumatology department, Hôpital de Boisguillaume, CHU de Rouen - Hôpitaux de Rouen, 76031 Rouen cedex, France.

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August 2003

Septic arthritis due to Actinomyces naeslundii: report of a case.

Joint Bone Spine 2002 Oct;69(5):499-501

Rheumatology Department, Rouen University Hospital Charles-Nicolle, Unit INSERM 519, IFR 23, 76000 Rouen cedex 76031, France.

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October 2002

[Synovial diseases of the hip].

Rev Prat 2002 Mar;52(6):611-5

Service de rhumatologie Centre hospitalier universitaire, Rouen-Hôpitaux, INSERM U519 et IFR 23, Rouen, Rouen.

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March 2002

The sternocostoclavicular joint: normal and abnormal features.

Joint Bone Spine 2002 Mar;69(2):161-9

Rheumatology Department, Hĵpital de Bois-Guillaume, CHU de Rouen, France.

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March 2002