Olivier Sitbon

Olivier Sitbon

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Olivier Sitbon

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Intensity and quality of exertional dyspnoea in patients with stable pulmonary hypertension.

Eur Respir J 2019 Nov 26. Epub 2019 Nov 26.

Sorbonne Université, INSERM, UMRS1158 Neurophysiologie respiratoire expérimentale et clinique, Paris, France.

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http://dx.doi.org/10.1183/13993003.02108-2018DOI Listing
November 2019

Predictors of survival in patients with not-operated chronic thromboembolic pulmonary hypertension.

J Heart Lung Transplant 2019 Aug 27;38(8):833-842. Epub 2019 Apr 27.

Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France; AP-HP, Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire, Hôpital Bicêtre, Le Kremlin-Bicêtre, France; Inserm UMR-S 999, Hôpital Marie Lannelongue, Le Plessis Robinson, France.

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http://dx.doi.org/10.1016/j.healun.2019.04.006DOI Listing
August 2019

Macitentan for the treatment of portopulmonary hypertension (PORTICO): a multicentre, randomised, double-blind, placebo-controlled, phase 4 trial.

Lancet Respir Med 2019 Jul 6;7(7):594-604. Epub 2019 Jun 6.

Division of Gastroenterology and Hepatology and Division Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1016/S2213-2600(19)30091-8DOI Listing
July 2019

Understanding the Similarities and Differences between Hepatic and Pulmonary Veno-Occlusive Disease.

Am J Pathol 2019 Jun 26;189(6):1159-1175. Epub 2019 Mar 26.

INSERM UMR_S 999, Pulmonary Arterial Hypertension: Physiopathology and Therapeutic Innovation, Marie Lannelongue Hospital, Le Plessis-Robinson, France; Department of Respiratory Medicine, University Paris-Sud, Medical School, University Paris-Saclay, Hôpitaux de Paris, National Reference Center for Severe Pulmonary Hypertension, Bicêtre Hospital, Le Kremlin Bicêtre, France. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2019.02.007DOI Listing
June 2019

Golden Ratio and the Proportionality Between Pulmonary Pressure Components in Pulmonary Arterial Hypertension.

Chest 2019 May 27;155(5):991-998. Epub 2018 Dec 27.

INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France; Department of Thoracic and Vascular Surgery and Heart-Lung Transplantation, Marie Lannelongue Hospital, Le Plessis-Robinson, France.

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http://dx.doi.org/10.1016/j.chest.2018.12.006DOI Listing
May 2019

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Authors:
Christopher J Rhodes Ken Batai Marta Bleda Matthias Haimel Laura Southgate Marine Germain Michael W Pauciulo Charaka Hadinnapola Jurjan Aman Barbara Girerd Amit Arora Jo Knight Ken B Hanscombe Jason H Karnes Marika Kaakinen Henning Gall Anna Ulrich Lars Harbaum Inês Cebola Jorge Ferrer Katie Lutz Emilia M Swietlik Ferhaan Ahmad Philippe Amouyel Stephen L Archer Rahul Argula Eric D Austin David Badesch Sahil Bakshi Christopher Barnett Raymond Benza Nitin Bhatt Harm J Bogaard Charles D Burger Murali Chakinala Colin Church John G Coghlan Robin Condliffe Paul A Corris Cesare Danesino Stéphanie Debette C Gregory Elliott Jean Elwing Melanie Eyries Terry Fortin Andre Franke Robert P Frantz Adaani Frost Joe G N Garcia Stefano Ghio Hossein-Ardeschir Ghofrani J Simon R Gibbs John Harley Hua He Nicholas S Hill Russel Hirsch Arjan C Houweling Luke S Howard Dunbar Ivy David G Kiely James Klinger Gabor Kovacs Tim Lahm Matthias Laudes Rajiv D Machado Robert V MacKenzie Ross Keith Marsolo Lisa J Martin Shahin Moledina David Montani Steven D Nathan Michael Newnham Andrea Olschewski Horst Olschewski Ronald J Oudiz Willem H Ouwehand Andrew J Peacock Joanna Pepke-Zaba Zia Rehman Ivan Robbins Dan M Roden Erika B Rosenzweig Ghulam Saydain Laura Scelsi Robert Schilz Werner Seeger Christian M Shaffer Robert W Simms Marc Simon Olivier Sitbon Jay Suntharalingam Haiyang Tang Alexander Y Tchourbanov Thenappan Thenappan Fernando Torres Mark R Toshner Carmen M Treacy Anton Vonk Noordegraaf Quinten Waisfisz Anna K Walsworth Robert E Walter John Wharton R James White Jeffrey Wilt Stephen J Wort Delphine Yung Allan Lawrie Marc Humbert Florent Soubrier David-Alexandre Trégouët Inga Prokopenko Richard Kittles Stefan Gräf William C Nichols Richard C Trembath Ankit A Desai Nicholas W Morrell Martin R Wilkins

Lancet Respir Med 2019 Mar 5;7(3):227-238. Epub 2018 Dec 5.

Department of Medicine, Imperial College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(18)30409-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391516PMC
March 2019

Validation of a risk assessment instrument for pulmonary arterial hypertension.

Eur Heart J 2018 12;39(47):4182-4185

Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1093/eurheartj/ehx301DOI Listing
December 2018

Association Between BMI and Obesity With Survival in Pulmonary Arterial Hypertension.

Chest 2018 10 22;154(4):872-881. Epub 2018 May 22.

Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France; Service de Pneumologie, Hôpital Bicêtre, AP-HP, Le Kremlin-Bicêtre, France; INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis Robinson, France.

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http://dx.doi.org/10.1016/j.chest.2018.05.006DOI Listing
October 2018

Clinical and Hemodynamic Correlates of Pulmonary Arterial Stiffness in Incident, Untreated Patients With Idiopathic Pulmonary Arterial Hypertension.

Chest 2018 10 27;154(4):882-892. Epub 2018 Jun 27.

INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis Robinson, France; Departement de Chirurgie Thoracique, Vasculaire et de Transplantation Pulmonaire, Hopital Marie Lannelongue, Le Plessis Robinson, France.

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http://dx.doi.org/10.1016/j.chest.2018.06.015DOI Listing
October 2018

Risk stratification in pulmonary arterial hypertension.

Curr Opin Pulm Med 2018 09;24(5):407-415

Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay.

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http://dx.doi.org/10.1097/MCP.0000000000000510DOI Listing
September 2018

Impact of the initiation of balloon pulmonary angioplasty program on referral of patients with chronic thromboembolic pulmonary hypertension to surgery.

J Heart Lung Transplant 2018 09 24;37(9):1102-1110. Epub 2018 May 24.

Research and Innovation Unit, INSERM U999, DHU Torino, Paris Sud University, Marie Lannelongue Hospital, Le Plessis Robinson, France; Department of Cardiothoracic Surgery, Marie Lannelongue Hospital, Le Plessis Robinson, France.

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http://dx.doi.org/10.1016/j.healun.2018.05.004DOI Listing
September 2018

Pulmonary hypertension associated with neurofibromatosis type 1.

Eur Respir Rev 2018 Sep 29;27(149). Epub 2018 Aug 29.

Université Paris-Sud, Faculté de Médecine, Paris, France.

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http://dx.doi.org/10.1183/16000617.0053-2018DOI Listing
September 2018

[Patient suddenly breathless].

Rev Prat 2018 Sep;68(7):753-760

Université Paris-Sud, faculté de médecine, université Paris-Saclay, Le Kremlin-Bicêtre, France. AP-HP, service de pneumologie, hôpital Bicêtre, Le Kremlin-Bicêtre, France. Inserm UMR_S 999, hôpital Marie- Lannelongue, Le Plessis-Robinson, France.

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September 2018

Pharmacovigilance in a rare disease: example of the VIGIAPATH program in pulmonary arterial hypertension.

Int J Clin Pharm 2018 Aug 13;40(4):790-794. Epub 2018 Aug 13.

INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis Robinson, France.

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http://dx.doi.org/10.1007/s11096-018-0712-yDOI Listing
August 2018

Pulmonary vascular remodeling patterns and expression of general control nonderepressible 2 (GCN2) in pulmonary veno-occlusive disease.

J Heart Lung Transplant 2018 05 4;37(5):647-655. Epub 2017 Oct 4.

Institut National de la Santé et de la Recherche Unités Mixtes de Recherche_S 999, Pulmonary Hypertension: Pathophysiology and Novel Therapies, Hôpital Marie Lannelongue, Le Plessis-Robinson, Paris, France; Faculty of Medicine, Paris-South University, Kremlin-Bicêtre, Paris, France; Department of Pathology, Hôpital Marie Lannelongue, Le Plessis-Robinson, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10532498173203
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http://dx.doi.org/10.1016/j.healun.2017.09.022DOI Listing
May 2018

Age, risk and outcomes in idiopathic pulmonary arterial hypertension.

Eur Respir J 2018 05 3;51(5). Epub 2018 May 3.

Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1183/13993003.00629-2018DOI Listing
May 2018

The Low-Risk Profile in Pulmonary Arterial Hypertension. Time for a Paradigm Shift to Goal-oriented Clinical Trial Endpoints?

Am J Respir Crit Care Med 2018 04;197(7):860-868

3 Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1164/rccm.201709-1840PPDOI Listing
April 2018

Outcome of Portopulmonary Hypertension After Liver Transplantation: Perhaps Not So Optimistic.

Transplantation 2018 04;102(4):e190-e191

University of Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin Bicêtre, France.

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http://dx.doi.org/10.1097/TP.0000000000002112DOI Listing
April 2018

Risk assessment in pulmonary arterial hypertension.

Eur Respir J 2018 03 29;51(3). Epub 2018 Mar 29.

Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France

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http://dx.doi.org/10.1183/13993003.00279-2018DOI Listing
March 2018

Prognostic Value of Follow-Up Hemodynamic Variables After Initial Management in Pulmonary Arterial Hypertension.

Circulation 2018 02 25;137(7):693-704. Epub 2017 Oct 25.

Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France (J.W., A.B., D.C., L.S., M.J., X.J., Y.T., C.O., F.P., C.S., P.H., G.S., D.M., M.H., O.S.)

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.029254DOI Listing
February 2018

Pulmonary hypertension due to left heart disease.

Arch Cardiovasc Dis 2017 Jun - Jul;110(6-7):420-431. Epub 2017 Apr 12.

AP-HP, Service de Cardiologie, Hôpital Bicêtre, Le Kremlin-Bicêtre, France; Univ. Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin Bicêtre, France.

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http://dx.doi.org/10.1016/j.acvd.2017.01.010DOI Listing
January 2018

Pulmonary Arterial Hypertension Associated With Systemic Lupus Erythematosus: Results From the French Pulmonary Hypertension Registry.

Chest 2018 01 26;153(1):143-151. Epub 2017 Aug 26.

Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre; AP-HP, Centre de reference de l'Hypertension Pulmonaire, Service de Pneumologie, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre; INSERM UMR_S999, LabEx LERMIT, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson, France.

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http://dx.doi.org/10.1016/j.chest.2017.08.014DOI Listing
January 2018

Acute decompensated pulmonary hypertension.

Eur Respir Rev 2017 Dec 15;26(146). Epub 2017 Nov 15.

Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1183/16000617.0092-2017DOI Listing
December 2017

Dead-space ventilation is linked to exercise capacity and survival in distal chronic thromboembolic pulmonary hypertension.

J Heart Lung Transplant 2017 Nov 22;36(11):1234-1242. Epub 2017 May 22.

Université Paris-Sud, Le Kremlin-Bicêtre, France; AP-HP, Service de Pneumologie, Centre de Référence de l׳Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre, France; INSERM UMR_S999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis-Robinson, France.

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http://dx.doi.org/10.1016/j.healun.2017.05.024DOI Listing
November 2017

Non-invasive diagnosis of pulmonary hypertension from lung Doppler signal: a proof of concept study.

J Clin Monit Comput 2017 Oct 19;31(5):903-910. Epub 2016 Aug 19.

Faculté de Médecine, Univ. Paris-Sud, 94270, Le Kremlin Bicêtre, France.

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http://dx.doi.org/10.1007/s10877-016-9923-8DOI Listing
October 2017

Medical Treatment of Pulmonary Arterial Hypertension.

Semin Respir Crit Care Med 2017 10 15;38(5):686-700. Epub 2017 Oct 15.

Univ. Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1055/s-0037-1607208DOI Listing
October 2017

Portopulmonary Hypertension.

Semin Respir Crit Care Med 2017 10 17;38(5):651-661. Epub 2017 Oct 17.

Faculté de Médecine, Univ. Paris-Sud, Université Paris-Saclay, Le Kremlin Bicêtre, France.

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http://dx.doi.org/10.1055/s-0037-1606251DOI Listing
October 2017

Exertional dyspnoea in pulmonary arterial hypertension.

Eur Respir Rev 2017 Sep 6;26(145). Epub 2017 Sep 6.

National Pulmonary Hypertension Service, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK

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http://dx.doi.org/10.1183/16000617.0039-2017DOI Listing
September 2017

Are indexed values better for defining exercise pulmonary hypertension?

Eur Respir J 2017 09 9;50(3). Epub 2017 Sep 9.

Service de Pneumologie, Assistance Publique-Hôpitaux de Paris, Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1183/13993003.00240-2017DOI Listing
September 2017

Impact of High-Priority Allocation on Lung and Heart-Lung Transplantation for Pulmonary Hypertension.

Ann Thorac Surg 2017 Aug 18;104(2):404-411. Epub 2017 May 18.

University Paris-Sud, Faculté de Médecine, Université-Paris-Saclay, Le Kremlin-Bicêtre; INSERM UMR_999, Institut National de la Santé et de la Recherche Médicale Unité Mixte de Recherche_S 999, Hôpital Marie Lannelongue, Le Plessis Robinson; Department of Thoracic and Vascular Surgery and Heart-Lung Transplantation, Hôpital Marie-Lannelongue, Le Plessis Robinson, Paris-Sud University, Paris, France.

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http://dx.doi.org/10.1016/j.athoracsur.2017.02.034DOI Listing
August 2017

Long-term outcome in liver transplantation candidates with portopulmonary hypertension.

Hepatology 2017 05 14;65(5):1683-1692. Epub 2017 Mar 14.

Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay, and AP-HP, Service de Pneumologie, Hôpital Bicêtre, Le Kremlin Bicêtre; INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis Robinson, France.

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http://dx.doi.org/10.1002/hep.28990DOI Listing
May 2017

Outcome of adults with Eisenmenger syndrome treated with drugs specific to pulmonary arterial hypertension: A French multicentre study.

Arch Cardiovasc Dis 2017 May 9;110(5):303-316. Epub 2017 Mar 9.

Adult congenital heart diseases unit, department of cardiology, centre de référence M3C, hôpital européen Georges-Pompidou, Assistance publique-Hôpitaux de Paris, Paris, France; Paris cardiovascular research centre (PARCC), Inserm U970, Paris Descartes University, Paris, France; Centre de référence malformations cardiaques congénitales complexes M3C, hôpital universitaire Necker-Enfants-Malades, Assistance publique-Hôpitaux de Paris, université Paris Descartes, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1016/j.acvd.2017.01.006DOI Listing
May 2017

Ambrisentan use for pulmonary arterial hypertension in a post-authorization drug registry: The VOLibris Tracking Study.

J Heart Lung Transplant 2017 Apr 6;36(4):399-406. Epub 2016 May 6.

Department of Experimental, Diagnostic and Specialty Medicine, Bologna University Hospital, Bologna, Italy.

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http://dx.doi.org/10.1016/j.healun.2016.04.013DOI Listing
April 2017

Long-term outcomes of pulmonary arterial hypertension under specific drug therapy in Eisenmenger syndrome.

J Heart Lung Transplant 2017 Apr 15;36(4):386-398. Epub 2016 Oct 15.

Faculté de Médecine Paris-Sud, Université Paris-Sud, Université Paris-Saclay, le Kremlin-Bicêtre, France; Inserm UMR-S 999, Hôpital Marie Lannelongue, Université Paris-Sud, Université Paris-Saclay, le Kremlin-Bicêtre, France; Laboratoire de Physiologie, Hôpital Marie-Lannelongue, Le Plessis-Robinson, France.

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http://dx.doi.org/10.1016/j.healun.2016.10.006DOI Listing
April 2017

Gut-Lung Connection in Pulmonary Arterial Hypertension.

Am J Respir Cell Mol Biol 2017 03;56(3):402-405

1 University Paris-Sud Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1165/rcmb.2015-0404LEDOI Listing
March 2017

Kinetics of Cardiac Output at the Onset of Exercise in Precapillary Pulmonary Hypertension.

Biomed Res Int 2016 20;2016:6050193. Epub 2016 Nov 20.

AP-HP, Centre de Référence de l'Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation (TORINO), Service de Pneumologie, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1155/2016/6050193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136420PMC
February 2017

Clinical phenotypes and outcomes of heritable and sporadic pulmonary veno-occlusive disease: a population-based study.

Lancet Respir Med 2017 02 11;5(2):125-134. Epub 2017 Jan 11.

University Paris-Sud, Faculté de Médecine, Paris, F-94270, France; AP-HP, Centre de Référence de l'Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation (TORINO), Service de Pneumologie, Hôpital de Bicêtre, Le Kremlin Bicêtre, Paris, France; UMR_S 999, Univ. Paris-Sud, INSERM, Laboratoire d'Excellence (LabEx) en Recherche sur le Médicament et l'Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(16)30438-6DOI Listing
February 2017

Macitentan Improves Health-Related Quality of Life for Patients With Pulmonary Arterial Hypertension: Results From the Randomized Controlled SERAPHIN Trial.

Chest 2017 Jan 23;151(1):106-118. Epub 2016 Sep 23.

Assistance Publique-Hôpitaux de Paris, Service de Pneumologie, Hôpital Bicêtre, Le Kremlin-Bicêtre, France; Université Paris-Sud, Laboratoire d'Excellence en Recherche sur le Médicament et Innovation Thérapeutique, Le Kremlin-Bicêtre, France, and INSERM U-999, Centre chirurgical Marie Lannelongue, Le Plessis Robinson, France.

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http://dx.doi.org/10.1016/j.chest.2016.08.1473DOI Listing
January 2017

A Clinical and Echocardiographic Score to Identify Pulmonary Hypertension Due to HFpEF.

J Card Fail 2017 Jan 11;23(1):29-35. Epub 2016 Oct 11.

AP-HP, Service de Cardiologie, Hôpital Bicêtre, Le Kremlin-Bicêtre, France; Univ. Paris-Sud, Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1016/j.cardfail.2016.10.002DOI Listing
January 2017

Epoprostenol and pulmonary arterial hypertension: 20 years of clinical experience.

Eur Respir Rev 2017 Jan 17;26(143). Epub 2017 Jan 17.

Dept of Pulmonology, Vrje Universiteit Medical Centre, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1183/16000617.0055-2016DOI Listing
January 2017

Beyond a single pathway: combination therapy in pulmonary arterial hypertension.

Eur Respir Rev 2016 Dec;25(142):408-417

National Pulmonary Hypertension Unit, Mater Misericordiae University Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1183/16000617.0085-2016DOI Listing
December 2016

Interferon-induced pulmonary hypertension: an update.

Curr Opin Pulm Med 2016 09;22(5):415-20

aUniversity Paris-Sud, Faculté de Médecine, Université Paris-Saclay bAP-HP, Service de Pneumologie, DHU Thorax Innovation, Hôpital Bicêtre cINSERM UMR_S 999, Hôpital Marie Lannelongue dFaculté de Pharmacie, University Paris-Sud eAP-HP, Service de Pharmacie, DHU Thorax Innovation, Hôpital Antoine Béclère, Paris, France.

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http://dx.doi.org/10.1097/MCP.0000000000000307DOI Listing
September 2016

Pulmonary arterial hypertension in idiopathic inflammatory myopathies: Data from the French pulmonary hypertension registry and review of the literature.

Medicine (Baltimore) 2016 Sep;95(39):e4911

aUniversity of Lille, INSERM U995, LIRIC, Lille Inflammation Research International Center bCHU Lille, Département de Médecine Interne et Immunologie Clinique cCentre National de Référence Maladies Systémiques et Auto-immunes Rares (Sclérodermie Systémique), Lille dUniversity Paris-Sud, Faculté de Médecine, Université Paris-Saclay eAP-HP, Service de Pneumologie, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre fINSERM UMR_S999, LabEx LERMIT, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson gDépartement de Médecine Interne et Immunologie Clinique, Centre National de Référence Maladies Neuromusculaires, Hôpital La Pitié-Salpêtrière, AP-HP, INSERM U974, Université Paris VI Pierre et Marie Curie, Paris hClinique Universitaire de Pneumologie, Centre Hospitalier Universitaire, Grenoble, France iUniversité Joseph Fourier, Grenoble jService de médecine interne et rhumatologie 3C/5D, Centre Hospitalier Universitaire Pierre Zobda-Quitman kDépartement de Cardiologie, Centre Hospitalier Universitaire Pierre Zobda-Quitman, Fort-de-France, Martinique lHospices Civils de Lyon, Service de Pneumologie, Centre de Compétence de l'Hypertension Pulmonaire, Centre de Référence des Maladies Pulmonaires Rares, Lyon mService de Médecine Interne, Centre de Référence des Vascularites Nécrosantes et de la Sclérodermie Systémique, Université Paris Descartes, Hôpital Cochin, Paris, France.

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http://dx.doi.org/10.1097/MD.0000000000004911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5265921PMC
September 2016

Diagnostic concordance of different criteria for exercise pulmonary hypertension in subjects with normal resting pulmonary artery pressure.

Eur Respir J 2016 07 30;48(1):254-7. Epub 2016 Mar 30.

Faculté de Médecine, Université Paris-Sud, Université Paris-Saclay, Le Kremlin-Bicêtre, France INSERM UMR_S999, Hôpital Marie Lannelongue, Le Plessis Robinson, France Département de Chirurgie Thoracique, Vasculaire et de Transplantation Pulmonaire, Hôpital Marie Lannelongue, Le Plessis Robinson, France.

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http://dx.doi.org/10.1183/13993003.01678-2015DOI Listing
July 2016

International Liver Transplant Society Practice Guidelines: Diagnosis and Management of Hepatopulmonary Syndrome and Portopulmonary Hypertension.

Transplantation 2016 Jul;100(7):1440-52

1 Pulmonary and Gastroenterology/Hepatology Division, Mayo Clinic, Rochester, MN. 2 Gastroenterology and Hepatology, University of Texas, Houston, TX. 3 Pulmonary Division, University of Pennsylvania, Philadelphia, PA. 4 University Medical Center Hamburg-Eppendorf, Hamburg, Germany. 5 Transplant Surgery, Mayo Clinic, Rochester, MN. 6 Department of Anesthesia, Baylor University Medical Center, Dallas, TX. 7 Pulmonary Division, Hôpital Bicêtre, University of Paris-Sud, Le Kremlin-Bicêtre, France. 8 Pediatric Gastroenterology, Hepatology and Nutrition Section, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO.

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http://dx.doi.org/10.1097/TP.0000000000001229DOI Listing
July 2016

Direct-Acting Antiviral Medications for Hepatitis C Virus Infection and Pulmonary Arterial Hypertension.

Chest 2016 07;150(1):256-8

Université Paris-Sud, Faculté de Médecine, le Kremlin Bicêtre, France; Assistance Publique-Hôpitaux de Paris (AP-HP), Service de Pneumologie, Département Hospitalo-Universitaire (DHU) Thorax Innovation, Hôpital Bicêtre, le Kremlin Bicêtre, France; INSERM UMR_S 999, Hôpital Marie Lannelongue, le Plessis Robinson, France.

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http://dx.doi.org/10.1016/j.chest.2016.04.031DOI Listing
July 2016

Regulatory T Cell Dysfunction in Idiopathic, Heritable and Connective Tissue-Associated Pulmonary Arterial Hypertension.

Chest 2016 06 21;149(6):1482-93. Epub 2016 Jan 21.

Inserm UMR_S 999, Hôpital Marie Lannelongue, Le Plessis Robinson, France; University of Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin Bicêtre, France; AP-HP, Service de Pneumologie, Hôpital Bicêtre, Le Kremlin Bicêtre, France.

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http://dx.doi.org/10.1016/j.chest.2016.01.004DOI Listing
June 2016

Initial dual oral combination therapy in pulmonary arterial hypertension.

Eur Respir J 2016 06 17;47(6):1727-36. Epub 2016 Mar 17.

Univ. Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France AP-HP, Service de Pneumologie, Hôpital Bicêtre, Le Kremlin-Bicêtre, France INSERM UMR_S 999, Hôpital Marie-Lannelongue, Le Plessis-Robinson, France.

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http://dx.doi.org/10.1183/13993003.02043-2015DOI Listing
June 2016

Non-Invasive Determination of Cardiac Output in Pre-Capillary Pulmonary Hypertension.

PLoS One 2015 30;10(7):e0134221. Epub 2015 Jul 30.

AP-HP, Centre de Référence de l'Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation (TORINO), Service de Pneumologie, Hôpital de Bicêtre, Le Kremlin Bicêtre, France; Université Paris-Sud, Faculté de Médecine, Le Kremlin Bicêtre, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134221PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520479PMC
May 2016

Resting pulmonary artery pressure of 21-24 mmHg predicts abnormal exercise haemodynamics.

Eur Respir J 2016 05 10;47(5):1436-44. Epub 2016 Mar 10.

AP-HP, Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre, France INSERM UMR_S999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France Dept de Chirurgie Thoracique, Vasculaire et de Transplantation Pulmonaire, Hopital Marie Lannelongue, Le Plessis Robinson, France.

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http://dx.doi.org/10.1183/13993003.01684-2015DOI Listing
May 2016

Lung capillary blood volume and membrane diffusion in precapillary pulmonary hypertension.

J Heart Lung Transplant 2016 05 6;35(5):647-56. Epub 2016 Jan 6.

Assistance Publique-Hôpitauxde Paris, Centre deRéférencedel' Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire Thorax Innovation, Service de Pneumologie, Hôpital de Bicêtre, LeKremlin Bicêtre, France; Faculté de Médecine, Univ. Paris-Sud, Le Kremlin Bicêtre; UMR_S 999, Univ. Paris-Sud, Institut National de la Santé et de la Recherche Médicale, Laboratoire d'Excellence en Recherche sur le Médicament et l'Innovation Thérapeutique, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2015.12.022DOI Listing
May 2016

Pulmonary veno-occlusive disease.

Eur Respir J 2016 05 23;47(5):1518-34. Epub 2016 Mar 23.

Univ Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin Bicêtre, France AP-HP, Service de Pneumologie, Hôpital Bicêtre, Le Kremlin Bicêtre, France Inserm UMR_S 999, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France

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http://dx.doi.org/10.1183/13993003.00026-2016DOI Listing
May 2016

Comparative Safety and Tolerability of Prostacyclins in Pulmonary Hypertension.

Drug Saf 2016 Apr;39(4):287-94

Univ. Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1007/s40264-015-0365-xDOI Listing
April 2016

Response to Letter Regarding Article, "Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Model".

Circulation 2016 Apr;133(14):e592-3

Faculté de Médecine, Université Paris-Sud, Kremlin-Bicêtre, France, AP-HP, Centre de Référence de l'Hypertension Pulmonaire Sévère, Service de Pneumologie, Hôpital de Bicêtre, Le Kremlin Bicêtre, France, UMR-S 999 INSERM, Université Paris-Sud, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.020946DOI Listing
April 2016

A rare case of sarcoidosis-associated pulmonary hypertension in a patient exposed to silica.

Eur Respir Rev 2016 Mar;25(139):93-6

Univ Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France AP-HP, Service de Pneumologie, Hôpital Bicêtre, Le Kremlin-Bicêtre, France INSERM UMR_S 999, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France.

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http://err.ersjournals.com/content/errev/25/139/93.full.pdf
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http://err.ersjournals.com/lookup/doi/10.1183/16000617.0073-
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http://dx.doi.org/10.1183/16000617.0073-2015DOI Listing
March 2016

Loss of Vascular Distensibility During Exercise Is an Early Hemodynamic Marker of Pulmonary Vascular Disease.

Chest 2016 Feb 12;149(2):353-361. Epub 2016 Jan 12.

Departement de Chirurgie Thoracique, Vasculaire et de Transplantation Pulmonaire, Hopital Marie Lannelongue, Le Plessis Robinson, France.

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http://dx.doi.org/10.1378/chest.15-0125DOI Listing
February 2016

Genetic counselling in a national referral centre for pulmonary hypertension.

Eur Respir J 2016 Feb 23;47(2):541-52. Epub 2015 Dec 23.

Université Paris Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin Bicêtre, France AP-HP, Centre de Référence de l'Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation (TORINO), Service de Pneumologie, Hôpital de Bicêtre, Le Kremlin Bicêtre, France UMR_S999, Université Paris-Sud, INSERM, Laboratoire d'Excellence (LabEx) en Recherche sur le Médicament et l'Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France

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http://erj.ersjournals.com/content/erj/early/2015/12/22/1399
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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.00717
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http://dx.doi.org/10.1183/13993003.00717-2015DOI Listing
February 2016

Patients', relatives', and practitioners' views of pulmonary arterial hypertension: A qualitative study.

Presse Med 2016 Feb 13;45(2):e11-27. Epub 2016 Jan 13.

Hôpital de Bicêtre, université Paris-Sud, service de pneumologie et soins intensifs, 78, rue du Général-Leclerc, 94275 Le Kremlin-Bicêtre, France. Electronic address:

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http://dx.doi.org/10.1016/j.lpm.2015.06.017DOI Listing
February 2016

[Tunnelled central venous line-associated infections in patients with pulmonary arterial hypertension treated with intravenous prostacyclin].

Presse Med 2016 Jan 4;45(1):20-8. Epub 2015 Nov 4.

AP-HP, hôpital Bicêtre, centre de référence de l'hypertension pulmonaire sévère, service de pneumologie et soins intensifs, DHU TORINO, 94275 Le Kremlin-Bicêtre, France; Université Paris-Sud, faculté de médecine, 94270 Le Kremlin-Bicêtre, France; Inserm U999, HTAP : « physiopathologie et innovation thérapeutique », 92350 Le Plessis-Robinson, France. Electronic address:

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http://dx.doi.org/10.1016/j.lpm.2015.10.001DOI Listing
January 2016

New pharmacotherapy options for pulmonary arterial hypertension.

Expert Opin Pharmacother 2015 12;16(14):2113-31. Epub 2015 Aug 12.

b 2 INSERM UMR_S999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue , Le Plessis Robinson, France.

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http://dx.doi.org/10.1517/14656566.2015.1074177DOI Listing
December 2015

Chronic thromboembolic pulmonary hypertension.

Presse Med 2015 Dec 12;44(12 Pt 2):e409-16. Epub 2015 Nov 12.

Université Paris-Saclay, faculté de médecine, 94270 Le Kremlin-Bicêtre, France; AP-HP, hôpital Bicêtre, service de pneumologie, 94270 Le Kremlin-Bicêtre, France; Centre chirurgical Marie-Lannelongue, Inserm UMR_S 999, 92060 Le Plessis-Robinson, France. Electronic address:

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http://err.ersjournals.com/content/errev/24/136/173.full.pdf
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http://www.cardiovascmed.ch/docs/cvm/2014/11/en/cvm_00285.pd
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http://medind.nic.in/iae/t09/i1/iaet09i1p45.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S075549821500472
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http://dx.doi.org/10.1016/j.lpm.2015.10.010DOI Listing
December 2015

Pulmonary arterial hypertension in patients treated with interferon.

Eur Respir J 2015 Dec;46(6):1851-3

AP-HP, Service de Pneumologie, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre, France INSERM U999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France Univ. Paris-Sud, Le Kremlin-Bicêtre, France.

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http://erj.ersjournals.com/content/46/6/1851.full.pdf
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http://erj.ersjournals.com/content/erj/46/6/1849.full.pdf
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http://erj.ersjournals.com/content/erj/44/6/1627.full.pdf
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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.01376
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http://dx.doi.org/10.1183/13993003.01376-2015DOI Listing
December 2015

Selexipag for the Treatment of Pulmonary Arterial Hypertension.

N Engl J Med 2015 Dec;373(26):2522-33

From Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, INSERM Unité Mixte de Recherche en Santé 999, Université Paris-Sud, Université Paris-Saclay, Le Kremlin-Bicêtre, France (O.S., G.S.); Massachusetts General Hospital, Boston (R.C.); UT Southwestern Medical Center, Dallas (K.M.C.); Actelion Pharmaceuticals, Allschwil, Switzerland (A.F., R.P., L.D.S.); National Pulmonary Hypertension Unit, Mater Misericordiae University Hospital, Dublin (S.G.); the Department of Experimental, Diagnostic and Specialty Medicine (DIMES) University of Bologna, Bologna, Italy (N.G.); University of Giessen and Marburg Lung Center, German Center of Lung Research, Giessen (H.-A.G), and the Department of Respiratory Medicine, Hannover Medical School and German Center of Lung Research, Hannover (M.M.H.) - both in Germany; the Department of Medicine, Imperial College London, London (H.-A.G.); Medical University of Vienna, Department of Internal Medicine II, Division of Cardiology, Allgemeines Krankenhaus, Vienna (I.M.L.); the Division of Pulmonary and Critical Care Medicine, University of California, San Diego (L.J.R.); the Division of Pulmonary and Critical Care Medicine, Cedars-Sinai Medical Center, Los Angeles (V.T.); Minsk Regional Clinical Hospital, Minsk, Belarus (I.A.); the Department of Pulmonary Circulation, Shanghai Pulmonary Hospital, Shanghai (J.L.), and the Department of Rheumatology, Peking Union Medical College Hospital, Beijing (X.Z.) - both in China; Federal Almazov North-West Medical Research Center, St. Petersburg, Russia (O.M.); and the Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Health System, Ann Arbor (V.V.M.).

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http://dx.doi.org/10.1056/NEJMoa1503184DOI Listing
December 2015

Pulmonary Hypertension Complicating Fibrosing Mediastinitis.

Medicine (Baltimore) 2015 Nov;94(44):e1800

From the University Paris-Sud, Faculté de Médecine (AS, AS, XJ, OP, LS, FP, DA, RJ, EF, OS, GS, MH, DM); AP-HP, Centre de Référence de l'Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation (TORINO), Service de Pneumologie, Hôpital de Bicêtre, Le Kremlin Bicêtre (AS, AS, XJ, LS, FP, DA, RJ, OS, GS, MH, DM); UMR_S 999, University Paris-Sud; INSERM; Laboratoire d'Excellence (LabEx) en Recherche sur le Médicament et l'Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson (AS, AS, XJ, LS, FP, DA, RJ, EF, OS, GS, MH, DM); AP-HP, Service de Radiologie, Hôpital Bicêtre, Le Kremlin-Bicêtre (OP); and Centre Chirurgical Marie Lannelongue, Service de Chirurgie Thoracique, Le Plessis Robinson, France (EF).

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http://dx.doi.org/10.1097/MD.0000000000001800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915879PMC
November 2015

Nasal decongestant exposure in patients with pulmonary arterial hypertension: a pilot study.

Eur Respir J 2015 Oct 23;46(4):1211-4. Epub 2015 Jul 23.

Université Paris-Sud, Faculté de Pharmacie, Châtenay Malabry, France UMRS 999, INSERM et Univ. Paris-Sud, Laboratoire d'Excellence (LabEx) en Recherche sur le Médicament et l'Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France AP-HP, Service de Pharmacie, Département Hospitalo-Universitaire (DHU) Thorax Innovation, Hôpital Antoine Béclère, Clamart, France

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http://erj.ersjournals.com/content/erj/46/4/1211.full.pdf
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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.00051
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http://dx.doi.org/10.1183/13993003.00051-2015DOI Listing
October 2015

The 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: a practical chronicle of progress.

Eur Respir J 2015 Oct;46(4):879-82

Univ. Paris-Sud, Le Kremlin-Bicêtre, France AP-HP, Service de Pneumologie, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre, France INSERM UMR_S999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France.

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http://dx.doi.org/10.1183/13993003.01177-2015DOI Listing
October 2015

Response to Letter Regarding Article, "Advances in Therapeutic Interventions for Patients With Pulmonary Arterial Hypertension".

Circulation 2015 Sep;132(12):e154

Univ. Paris-Sud, Le Kremlin-Bicêtre, FranceAP-HP, Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre, FranceINSERM UMR_S999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.016226DOI Listing
September 2015