Publications by authors named "Olivier Michielin"

100Publications

Evolving impact of long-term survival results on metastatic melanoma treatment.

J Immunother Cancer 2020 Oct;8(2)

Melanoma Cancer Immunotherapy and Innovative Therapy Unit, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy

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http://dx.doi.org/10.1136/jitc-2020-000948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549477PMC
October 2020

[ENT management of head and neck cutaneous melanoma].

Rev Med Suisse 2020 Oct;16(709):1853-1859

Service d'ORL et de chirurgie cervico-faciale, CHUV, 1011 Lausanne.

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October 2020

Intratumoural immunotherapies for unresectable and metastatic melanoma: current status and future perspectives.

Br J Cancer 2020 Sep 27;123(6):885-897. Epub 2020 Jul 27.

Department of Dermatology, Venereology and Allergology, University Hospital Schleswig-Holstein, Kiel, Germany.

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http://dx.doi.org/10.1038/s41416-020-0994-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492252PMC
September 2020

[Locally advanced and metastatic melanoma : novelties].

Rev Med Suisse 2020 May;16(695):1092-1097

Service d'oncologie médicale, Département d'oncologie, CHUV, 1011 Lausanne.

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May 2020

TERAVOLT: Thoracic Cancers International COVID-19 Collaboration.

Cancer Cell 2020 06 16;37(6):742-745. Epub 2020 May 16.

Department of Medicine, Division of Hematology & Oncology, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2020.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229923PMC
June 2020

[Oncology: navigating the COVID-19 Pandemic and Steer the Course].

Rev Med Suisse 2020 Apr;16(N° 691-2):819-822

Service d'oncologie médicale, CHUV, 1011 Lausanne.

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April 2020

Integrating radiomics into holomics for personalised oncology: from algorithms to bedside.

Eur Radiol Exp 2020 02 7;4(1):11. Epub 2020 Feb 7.

Personalised Analytic Oncology, Department of Oncology, Lausanne University Hospital, Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s41747-019-0143-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007467PMC
February 2020

Herpes simplex encephalitis in adult patients with MASP-2 deficiency.

PLoS Pathog 2019 12 23;15(12):e1008168. Epub 2019 Dec 23.

Infectious Diseases Service, Department of Medicine, University Hospital and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1008168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944389PMC
December 2019

The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study.

J Neurooncol 2020 Jan 14;146(1):181-193. Epub 2019 Dec 14.

Centre Hospitalier Universitaire Vaudois (CHUV), Oncology Service, Precision Oncology Center, Oncology Department, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/s11060-019-03363-0DOI Listing
January 2020

Multiple nivolumab-induced CNS demyelination with spontaneous resolution in an asymptomatic metastatic melanoma patient.

J Immunother Cancer 2019 12 2;7(1):336. Epub 2019 Dec 2.

Department of Medical Oncology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s40425-019-0818-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889661PMC
December 2019

First-Line Selective Internal Radiation Therapy in Patients with Uveal Melanoma Metastatic to the Liver.

J Nucl Med 2020 03 3;61(3):350-356. Epub 2019 Sep 3.

Department of Radiology and Interventional Radiology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland

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http://dx.doi.org/10.2967/jnumed.119.230870DOI Listing
March 2020

SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules.

Nucleic Acids Res 2019 07;47(W1):W357-W364

Molecular Modeling Group, SIB Swiss Institute of Bioinformatics, University of Lausanne, Quartier UNIL-Sorge, Bâtiment Amphipôle, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1093/nar/gkz382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602486PMC
July 2019

[Oncology, what's new in 2018].

Rev Med Suisse 2019 Jan;15(N° 632-633):78-81

Service d'oncologie médicale, Département d'oncologie, CHUV, 1011 Lausanne.

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January 2019

New therapeutic perspectives to manage refractory immune checkpoint-related toxicities.

Lancet Oncol 2019 01;20(1):e54-e64

Service Immunologie et Allergie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland; Centre d'Immunothérapie et de Vaccinologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland; Faculté Médecine Paris Descartes, Université Paris Descartes, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183082
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http://dx.doi.org/10.1016/S1470-2045(18)30828-3DOI Listing
January 2019

A severe case of neuro-Sjögren's syndrome induced by pembrolizumab.

J Immunother Cancer 2018 10 22;6(1):110. Epub 2018 Oct 22.

Department of Medicine, Division of Immunology and Allergy, Lausanne University Hospital CHUV, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s40425-018-0429-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196470PMC
October 2018

Practice-Changing Developments in Stage III Melanoma: Surgery, Adjuvant Targeted Therapy, and Immunotherapy.

Am Soc Clin Oncol Educ Book 2018 May;38:759-762

From the Department of Hematology/Oncology, Winship Cancer Institute, Emory University, Atlanta, GA; Department of Oncology, Lausanne University Hospital, Lausanne, Switzerland; Department of Surgical Oncology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands.

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http://dx.doi.org/10.1200/EDBK_200241DOI Listing
May 2018

Pan-SRC kinase inhibition blocks B-cell receptor oncogenic signaling in non-Hodgkin lymphoma.

Blood 2018 05 22;131(21):2345-2356. Epub 2018 Mar 22.

Swiss Institute for Experimental Cancer Research, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1182/blood-2017-10-809210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969377PMC
May 2018

Quantification of the next-generation oral anti-tumor drugs dabrafenib, trametinib, vemurafenib, cobimetinib, pazopanib, regorafenib and two metabolites in human plasma by liquid chromatography-tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2018 Apr 8;1083:124-136. Epub 2018 Feb 8.

Laboratory of the Service of Clinical Pharmacology, Department of Laboratories, Lausanne University Hospital, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2018.02.008DOI Listing
April 2018

Benefit of the nivolumab and ipilimumab combination in pretreated advanced melanoma.

Eur J Cancer 2018 04 12;93:147-149. Epub 2018 Feb 12.

APHP Dermatology, Department of Dermatology and CIC, Paris 7 Diderot University, INSERM U976, Hôpital Saint-Louis, Paris, France.

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http://dx.doi.org/10.1016/j.ejca.2018.01.062DOI Listing
April 2018

Mutant and histological heterogeneity define metabolic subtypes of hepatoblastoma.

EMBO Mol Med 2017 11;9(11):1589-1604

Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

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http://dx.doi.org/10.15252/emmm.201707814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666308PMC
November 2017

A practical guide to the handling and administration of talimogene laherparepvec in Europe.

Onco Targets Ther 2017 2;10:3867-3880. Epub 2017 Aug 2.

Skin Cancer Centre/Dermatology Clinic, Universitätsspital Zürich, Zurich, Switzerland.

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http://dx.doi.org/10.2147/OTT.S133699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546812PMC
August 2017

The Binding Mode of N-Hydroxyamidines to Indoleamine 2,3-Dioxygenase 1 (IDO1).

Biochemistry 2017 08 27;56(33):4323-4325. Epub 2017 Jul 27.

Molecular Modeling Group, SIB Swiss Institute of Bioinformatics , 1015 Lausanne, Switzerland.

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http://pubs.acs.org/doi/10.1021/acs.biochem.7b00586
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http://dx.doi.org/10.1021/acs.biochem.7b00586DOI Listing
August 2017

Multicenter, real-life experience with checkpoint inhibitors and targeted therapy agents in advanced melanoma patients in Switzerland.

Melanoma Res 2017 08;27(4):358-368

aDepartment of Dermatology, University Hospital Zurich bUniversity of Zurich cHorten Centre for Patient Oriented Research and Knowledge Transfer, University of Zurich, Zurich dDepartment of Internal Medicine, Cantonal Hospital Aarau, Aarau eDepartment of Oncology, Cantonal Hospital Graubünden, Chur fService of Medical Oncology, Department of Oncology, University Hospital of Lausanne, Lausanne, Switzerland gUniversity of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1097/CMR.0000000000000359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633326PMC
August 2017

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules.

Sci Rep 2017 03 3;7:42717. Epub 2017 Mar 3.

SIB Swiss Institute of Bioinformatics, Molecular Modeling Group, Quartier Sorge, Bâtiment Génopode, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1038/srep42717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335600PMC
March 2017

Combining talimogene laherparepvec with immunotherapies in melanoma and other solid tumors.

Cancer Immunol Immunother 2017 Jun 25;66(6):683-695. Epub 2017 Feb 25.

Lausanne University Hospital, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/s00262-017-1967-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445176PMC
June 2017

ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016.

Authors:
Christian Dittrich Michael Kosty Svetlana Jezdic Doug Pyle Rossana Berardi Jonas Bergh Nagi El-Saghir Jean-Pierre Lotz Pia Österlund Nicholas Pavlidis Gunta Purkalne Ahmad Awada Susana Banerjee Smita Bhatia Jan Bogaerts Jan Buckner Fatima Cardoso Paolo Casali Edward Chu Julia Lee Close Bertrand Coiffier Roisin Connolly Sarah Coupland Luigi De Petris Maria De Santis Elisabeth G E de Vries Don S Dizon Jennifer Duff Linda R Duska Alexandru Eniu Marc Ernstoff Enriqueta Felip Martin F Fey Jill Gilbert Nicolas Girard Andor W J M Glaudemans Priya K Gopalan Axel Grothey Stephen M Hahn Diana Hanna Christian Herold Jørn Herrstedt Krisztian Homicsko Dennie V Jones Lorenz Jost Ulrich Keilholz Saad Khan Alexander Kiss Claus-Henning Köhne Rainer Kunstfeld Heinz-Josef Lenz Stuart Lichtman Lisa Licitra Thomas Lion Saskia Litière Lifang Liu Patrick J Loehrer Merry Jennifer Markham Ben Markman Marius Mayerhoefer Johannes G Meran Olivier Michielin Elizabeth Charlotte Moser Giannis Mountzios Timothy Moynihan Torsten Nielsen Yuichiro Ohe Kjell Öberg Antonio Palumbo Fedro Alessandro Peccatori Michael Pfeilstöcker Chandrajit Raut Scot C Remick Mark Robson Piotr Rutkowski Roberto Salgado Lidia Schapira Eva Schernhammer Martin Schlumberger Hans-Joachim Schmoll Lowell Schnipper Cristiana Sessa Charles L Shapiro Julie Steele Cora N Sternberg Friedrich Stiefel Florian Strasser Roger Stupp Richard Sullivan Josep Tabernero Luzia Travado Marcel Verheij Emile Voest Everett Vokes Jamie Von Roenn Jeffrey S Weber Hans Wildiers Yosef Yarden

ESMO Open 2016 29;1(5):e000097. Epub 2016 Sep 29.

Department of General Medical Oncology , University Hospitals Leuven , Leuven , Belgium.

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http://dx.doi.org/10.1136/esmoopen-2016-000097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070299PMC
September 2016

The cutting edge of metastatic melanoma therapy.

Melanoma Manag 2016 Sep 22;3(3):217-229. Epub 2016 Aug 22.

Department of Oncology, Centre Hospitalier Universitaire Vaudois, Bugnon 46, 1011 Lausanne, Switzerland.

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https://www.futuremedicine.com/doi/10.2217/mmt-2016-0026
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http://dx.doi.org/10.2217/mmt-2016-0026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094682PMC
September 2016

1,2,3-Triazoles as inhibitors of indoleamine 2,3-dioxygenase 2 (IDO2).

Bioorg Med Chem Lett 2016 09 16;26(17):4330-3. Epub 2016 Jul 16.

Molecular Modeling Group, SIB Swiss Institute for Bioinformatics, CH-1015 Lausanne, Switzerland; Ludwig Center for Cancer Research of the University of Lausanne, CH-1066 Epalinges, Switzerland; Department of Oncology, University of Lausanne and Centre Hospitalier Universitaire Vaudois (CHUV), CH-1011 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.07.031DOI Listing
September 2016

SwissSimilarity: A Web Tool for Low to Ultra High Throughput Ligand-Based Virtual Screening.

J Chem Inf Model 2016 08 19;56(8):1399-404. Epub 2016 Jul 19.

SIB Swiss Institute of Bioinformatics, Quartier Sorge, Bâtiment Génopode , CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1021/acs.jcim.6b00174DOI Listing
August 2016

Systematic review of the use of granulocyte-macrophage colony-stimulating factor in patients with advanced melanoma.

Cancer Immunol Immunother 2016 09 2;65(9):1015-34. Epub 2016 Jul 2.

Division of Immunology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, Netherlands.

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http://dx.doi.org/10.1007/s00262-016-1860-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995227PMC
September 2016

Design and Validation of a Novel Generic Platform for the Production of Tetravalent IgG1-like Bispecific Antibodies.

J Immunol 2016 Apr 26;196(7):3199-211. Epub 2016 Feb 26.

Centre National de la Recherche Scientifique UPS3044 "Baculovirus et Thérapie," F-30380 Saint-Christol-Lèz Alès, France;

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http://dx.doi.org/10.4049/jimmunol.1501592DOI Listing
April 2016

Attracting cavities for docking. Replacing the rough energy landscape of the protein by a smooth attracting landscape.

J Comput Chem 2016 Feb 12;37(4):437-47. Epub 2015 Nov 12.

Bâtiment Génopode, SIB Swiss Institute of Bioinformatics, Quartier Sorge, CH-1015 Lausanne, Switzerland.

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http://doi.wiley.com/10.1002/jcc.24249
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http://dx.doi.org/10.1002/jcc.24249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738475PMC
February 2016

Gaining momentum: New options and opportunities for the treatment of advanced melanoma.

Cancer Treat Rev 2015 Sep 4;41(8):660-70. Epub 2015 Jun 4.

Department of Dermatology, Medical University Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2015.05.012DOI Listing
September 2015

Challenges in the Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors.

J Med Chem 2015 Dec 26;58(24):9421-37. Epub 2015 May 26.

Molecular Modeling Group, SIB Swiss Institute of Bioinformatics , CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1021/acs.jmedchem.5b00326DOI Listing
December 2015

iLOGP: a simple, robust, and efficient description of n-octanol/water partition coefficient for drug design using the GB/SA approach.

J Chem Inf Model 2014 Dec 25;54(12):3284-301. Epub 2014 Nov 25.

Molecular Modeling Group, SIB Swiss Institute of Bioinformatics , Quartier Sorge, Bâtiment Génopode, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1021/ci500467kDOI Listing
December 2014

Pulmonary sarcoid-like granulomatosis after multiple vaccinations of a long-term surviving patient with metastatic melanoma.

Cancer Immunol Res 2014 Dec 2;2(12):1148-53. Epub 2014 Oct 2.

Clinical and Tumor Biology and Immunotherapy Unit, Department of Oncology and Ludwig Cancer Research Center, University of Lausanne (UNIL), Lausanne, Switzerland.

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http://dx.doi.org/10.1158/2326-6066.CIR-14-0143DOI Listing
December 2014

Dramatic response of vemurafenib-induced cutaneous lesions upon switch to dual BRAF/MEK inhibition in a metastatic melanoma patient.

Melanoma Res 2014 Oct;24(5):496-500

Departments of aOncology bDermatology cPathology, CHUV, Lausanne dService of Hemato-Oncology, Department of Internal Medicine, Hospital of Fribourg, Fribourg, Switzerland.

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http://dx.doi.org/10.1097/CMR.0000000000000055DOI Listing
October 2014

Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.

Eur J Med Chem 2014 Sep 10;84:284-301. Epub 2014 Jul 10.

Swiss Institute of Bioinformatics, Molecular Modeling Group, Quartier Sorge - Bâtiment Génopode, CH-1015 Lausanne, Switzerland; Department of Oncology, University of Lausanne and Centre Hospitalier Universitaire Vaudois (CHUV), CH-1011 Lausanne, Switzerland; Ludwig Center for Cancer Research of the University of Lausanne, CH-1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2014.06.078DOI Listing
September 2014

A WXW motif is required for the anticancer activity of the TAT-RasGAP317-326 peptide.

J Biol Chem 2014 Aug 9;289(34):23701-11. Epub 2014 Jul 9.

From the Department of Physiology, University of Lausanne, 1005 Lausanne, Switzerland,

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http://dx.doi.org/10.1074/jbc.M114.576272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156047PMC
August 2014

[Genomics medicine and oncology].

Praxis (Bern 1994) 2014 May;103(10):591-6

Département d'oncologie, CHUV Lausanne.

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http://dx.doi.org/10.1024/1661-8157/a001659DOI Listing
May 2014

SwissTargetPrediction: a web server for target prediction of bioactive small molecules.

Nucleic Acids Res 2014 Jul 3;42(Web Server issue):W32-8. Epub 2014 May 3.

Swiss Institute of Bioinformatics (SIB), Quartier Sorge, Bâtiment Génopode, CH-1015 Lausanne, Switzerland

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http://nar.oxfordjournals.org/content/early/2014/05/03/nar.g
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http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gku293
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http://dx.doi.org/10.1093/nar/gku293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086140PMC
July 2014

Successes and limitations of targeted cancer therapy in melanoma.

Prog Tumor Res 2014 17;41:78-88. Epub 2014 Feb 17.

Department of Oncology, Lausanne University Hospital, Lausanne, Switzerland.

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http://dx.doi.org/10.1159/000355903DOI Listing
April 2015

The peroxisomal enzyme L-PBE is required to prevent the dietary toxicity of medium-chain fatty acids.

Cell Rep 2013 Oct 26;5(1):248-58. Epub 2013 Sep 26.

Center for Integrative Genomics, University of Lausanne, Lausanne 1015, Switzerland.

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http://dx.doi.org/10.1016/j.celrep.2013.08.032DOI Listing
October 2013

Shaping the interaction landscape of bioactive molecules.

Bioinformatics 2013 Dec 17;29(23):3073-9. Epub 2013 Sep 17.

Swiss Institute of Bioinformatics (SIB), Quartier Sorge, Bâtiment Génopode, CH-1015 Lausanne, Switzerland, Ludwig Institute for Cancer Research and Pluridisciplinary Center for Clinical Oncology, Centre Hospitalier Universitaire Vaudois, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1093/bioinformatics/btt540DOI Listing
December 2013

Lung adenocarcinoma with BRAF G469L mutation refractory to vemurafenib.

Lung Cancer 2013 Nov 19;82(2):365-7. Epub 2013 Aug 19.

Department of Medical Oncology, Luzerner Kantonsspital, Luzern, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2013.08.012DOI Listing
November 2013

Identification of multiple mechanisms of resistance to vemurafenib in a patient with BRAFV600E-mutated cutaneous melanoma successfully rechallenged after progression.

Clin Cancer Res 2013 Oct 15;19(20):5749-57. Epub 2013 Aug 15.

Authors' Affiliations: Department of Oncology, University Hospital of Lausanne; Genomic Technologies Facility (GTF), Center for Integrative Genomics, University of Lausanne; Vital-IT, Swiss Institute of Bioinformatics, and the Ludwig Center for Cancer Research of the University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0661DOI Listing
October 2013

Improving binding affinity and stability of peptide ligands by substituting glycines with D-amino acids.

Chembiochem 2013 Jul 4;14(11):1316-22. Epub 2013 Jul 4.

Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, BCH 5305 (Batochime), Avenue Forel 2, 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1002/cbic.201300228DOI Listing
July 2013

Protein pocket and ligand shape comparison and its application in virtual screening.

J Comput Aided Mol Des 2013 Jun 27;27(6):511-24. Epub 2013 Jun 27.

Computational Chemistry, Merck Serono S.A. Geneva, Chemin des Mines 9, 1202 Geneva, Switzerland.

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http://dx.doi.org/10.1007/s10822-013-9659-1DOI Listing
June 2013

[New therapeutic weapons in stage IV melanoma].

Rev Med Suisse 2013 May;9(387):1095-8

Département d'oncologie, CHUV, 1011 Lausanne.

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May 2013

Dramatic response induced by vemurafenib in a BRAF V600E-mutated lung adenocarcinoma.

J Clin Oncol 2013 Jul 3;31(20):e341-4. Epub 2013 Jun 3.

Centre Hospitalier Universitaire Vaudois, Oncology Department, CHUV BH06, Rue du Bugnon 46, 1011 Lausanne, Switzerland.

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http://dx.doi.org/10.1200/JCO.2012.47.6143DOI Listing
July 2013

RNA pentaloop structures as effective targets of regulators belonging to the RsmA/CsrA protein family.

RNA Biol 2013 Jun 23;10(6):1031-41. Epub 2013 Apr 23.

Département de Microbiologie Fondamentale, Université de Lausanne, Bâtiment Biophore, Lausanne, Switzerland.

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http://dx.doi.org/10.4161/rna.24771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111731PMC
June 2013

SHP-1 phosphatase activity counteracts increased T cell receptor affinity.

J Clin Invest 2013 Mar 8;123(3):1044-56. Epub 2013 Feb 8.

Department of Oncology, Lausanne University Hospital Center and University of Lausanne, Lausanne, Switzerland.

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http://www.jci.org/articles/view/65325
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http://dx.doi.org/10.1172/JCI65325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582132PMC
March 2013

A dramatic lung cancer course in a patient with a rare EGFR germline mutation exon 21 V843I: Is EGFR TKI resistance predictable?

Lung Cancer 2013 Apr 4;80(1):81-4. Epub 2013 Feb 4.

HFR Fribourg, Hôpital Cantonal, Department of Internal Medicine, Division of Oncology, Fribourg, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S01695002120063
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http://dx.doi.org/10.1016/j.lungcan.2012.11.013DOI Listing
April 2013

T-cell receptors binding orientation over peptide/MHC class I is driven by long-range interactions.

PLoS One 2012 14;7(12):e51943. Epub 2012 Dec 14.

Multidisciplinary Oncology Center, Lausanne University Hospital (CHUV), Lausanne, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0051943PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522592PMC
September 2013

SwissBioisostere: a database of molecular replacements for ligand design.

Nucleic Acids Res 2013 Jan 17;41(Database issue):D1137-43. Epub 2012 Nov 17.

Computational Chemistry, Merck Serono S.A., Chemin des Mines, 9, CH-1202 Geneva.

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http://dx.doi.org/10.1093/nar/gks1059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531158PMC
January 2013

SwissSidechain: a molecular and structural database of non-natural sidechains.

Nucleic Acids Res 2013 Jan 26;41(Database issue):D327-32. Epub 2012 Oct 26.

Swiss Institute of Bioinformatics (SIB), Quartier Sorge, Bâtiment Génopode, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1093/nar/gks991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531096PMC
January 2013

Defining and searching for structural motifs using DeepView/Swiss-PdbViewer.

BMC Bioinformatics 2012 Jul 23;13:173. Epub 2012 Jul 23.

Vital-IT Group, SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
Publisher Site
http://dx.doi.org/10.1186/1471-2105-13-173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436773PMC
July 2012