Olivier Hermine

Olivier Hermine

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Olivier Hermine

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Synthesis, 3D-structure and stability analyses of NRPa-308, a new promising anti-cancer agent.

Bioorg Med Chem Lett 2019 Dec 16;29(24):126710. Epub 2019 Oct 16.

Université de Paris, CiTCoM, UMR 8038 CNRS, Faculté de Pharmacie, F-75006 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2019.126710DOI Listing
December 2019

Epstein-Barr Virus (EBV)-Related Lymphoproliferative Disorders in Ataxia Telangiectasia: Does ATM Regulate EBV Life Cycle?

Front Immunol 2018 4;9:3060. Epub 2019 Jan 4.

INSERM U1163/CNRS ERL8254 - Laboratory of cellular and molecular mechanisms of hematological disorders and therapeutic implications, IMAGINE Institute, Paris, France.

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http://dx.doi.org/10.3389/fimmu.2018.03060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329310PMC
October 2019

A 1-Year Prospective French Nationwide Study of Emergency Hospital Admissions in Children and Adults with Primary Immunodeficiency.

Authors:
Hélène Coignard-Biehler Nizar Mahlaoui Benoit Pilmis Vincent Barlogis Pauline Brosselin Nathalie De Vergnes Marianne Debré Marion Malphettes Pierre Frange Emilie Catherinot Isabelle Pellier Isabelle Durieu Antoinette Perlat Bruno Royer Alain Le Quellec Eric Jeziorski Alain Fischer Olivier Lortholary Laurent Aaron Daniel Adoue Claire Aguilar Nathalie Aladjidi Alexandre Alcais Zahir Amoura Philippe Arlet Corinne Armari-Alla Brigitte Bader-Meunier Sophie Bayart Yves Bertrand Boris Bienvenu Stéphane Blanche Damien Bodet Bernard Bonnotte Raphaël Borie Patrick Boutard Claire Briandet Jean-Paul Brion Jacques Brouard Sarah Cohen-Beaussant Laurence Costes Louis-Jean Couderc Pierre Cougoul Virginie Courteille Geneviève de Saint Basile Catherine Devoldere Anne Deville Jean Donadieu Eric Dore Fabienne Dulieu Christine Edan Natacha Entz-Werle Claire Fieschi Amandine Forestier Fanny Fouyssac Vincent Gajdos Lionel Galicier Virginie Gandemer Martine Gardembas Catherine Gaud Gaelle Guillerm Eric Hachulla Mohamed Hamidou Olivier Hermine Cyrille Hoarau Sébastien Humbert Arnaud Jaccard Serge Jacquot Jean-Philippe Jais Roland Jaussaud Pierre-Yves Jeandel Kamila Kebaili Anne-Sophie Korganow Olivier Lambotte Fanny Lanternier Claire Larroche Anne-Sophie Lascaux Emmanuelle Le Moigne Vincent Le Moing Yvon Lebranchu Marc Lecuit Guillaume Lefevre Richard Lemal Valérie Li Thiao Te Aude Marie-Cardine Nicolas Martin Silva Agathe Masseau Christian Massot Françoise Mazingue Etienne Merlin Gérard Michel Frédéric Millot Béatrice Monlibert Fabrice Monpoux Despina Moshous Luc Mouthon Martine Munzer Bénédicte Neven Raphaëlle Nove-Josserand Eric Oksenhendler Marie Ouachée-Chardin Caroline Oudot Anne Pagnier Jean-Louis Pasquali Marlène Pasquet Yves Perel Capucine Picard Christophe Piguet Dominique Plantaz Johan Provot Pierre Quartier Frédéric Rieux-Laucat Pascal Roblot Pierre-Marie Roger Pierre-Simon Rohrlich Hervé Rubie Valéry Salle Françoise Sarrot-Reynauld Amélie Servettaz Jean-Louis Stephan Nicolas Schleinitz Felipe Suarez Laure Swiader Sophie Taque Caroline Thomas Olivier Tournilhac Caroline Thumerelle François Tron Jean-Pierre Vannier Jean-François Viallard

J Clin Immunol 2019 Oct 10;39(7):702-712. Epub 2019 Aug 10.

Service de Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker Pasteur, Hôpital Universitaire Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université de Paris, Paris, France.

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http://dx.doi.org/10.1007/s10875-019-00658-9DOI Listing
October 2019

Urea moiety as amide bond mimetic in peptide-like inhibitors of VEGF-A/NRP-1 complex.

Bioorg Med Chem Lett 2019 Sep 10;29(17):2493-2497. Epub 2019 Jul 10.

Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland; Department of Neuropeptides, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5, 02-106 Warsaw, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2019.07.016DOI Listing
September 2019

Innate-like T cells in children with sickle cell disease.

PLoS One 2019 28;14(6):e0219047. Epub 2019 Jun 28.

Laboratory of Immunoregulation and Immunopathology, Institut Necker-Enfants malades, Centre National de la Recherche Scientifique (CNRS) UMR 8253, Inserm UMR 1151, Paris Descartes - Sorbonne Paris Cité University, Paris, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219047PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599217PMC
June 2019

Neuroinflammatory disorders and mastocytosis: A possible association?

J Allergy Clin Immunol Pract 2019 Nov - Dec;7(8):2878-2881.e1. Epub 2019 May 8.

Centre de référence des mastocytoses (CEREMAST), Université Paris Descartes, Sorbonne, Paris Cité, Necker Enfants Malades Hospital, Imagine Foundation, Paris, France; INSERM U1163 and CNRS ERL 8254, Laboratory of Physiopathology and Treatment of Hematological Disorders, Paris, France; Adults Haematology Unit, Université Paris Descartes, Sorbonne, Paris Cité, Assistance Publique-Hôpitaux de Paris, Imagine Foundation, Necker-Enfants Malades Hospital, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2019.04.033DOI Listing
May 2019

Omalizumab Therapy for Mast Cell-Mediator Symptoms in Patients with ISM, CM, MMAS, and MCAS.

J Allergy Clin Immunol Pract 2019 Sep - Oct;7(7):2387-2395.e3. Epub 2019 Apr 5.

Imagine Institute, INSERM U1163 and CNRS ERL 8654, Paris Descartes University, Sorbonne Paris Cité, Paris, France; Department of Hematology, Necker Children's Hospital, APHP, Paris, France; French Reference Center for Mastocytosis (CEREMAST), Necker Children's Hospital, APHP, Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S22132198193032
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http://dx.doi.org/10.1016/j.jaip.2019.03.039DOI Listing
April 2019

Efficacy of Ruxolitinib Therapy in a Patient With Severe Enterocolitis Associated With a STAT3 Gain-of-Function Mutation.

Gastroenterology 2019 03 15;156(4):1206-1210.e1. Epub 2018 Dec 15.

Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France; AP-HP, Gastroenterology, Hôpital Cochin, Paris, France. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2018.11.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433619PMC
March 2019

Rituximab-Bendamustine (R-Benda) in MALT lymphoma complicating primary Sjögren syndrome (pSS).

Br J Haematol 2019 02 9;184(3):472-475. Epub 2018 Feb 9.

Department of Rheumatology, AP-HP, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1111/bjh.15120DOI Listing
February 2019

Serotonin, hematopoiesis and stem cells.

Pharmacol Res 2019 02 11;140:67-74. Epub 2018 Aug 11.

Institut Imagine, INSERM U1163 - CNRS ERL8254, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2018.08.005DOI Listing
February 2019

Neuropilin-1 peptide-like ligands with proline mimetics, tested using the improved chemiluminescence affinity detection method.

Medchemcomm 2019 Feb 25;10(2):332-340. Epub 2019 Jan 25.

Faculty of Chemistry , University of Warsaw , Pasteura 1 , 02-093 Warsaw , Poland . Email: ; Email:

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http://dx.doi.org/10.1039/c8md00537kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390686PMC
February 2019

Mast cell activation syndrome: High frequency of skin manifestations and anaphylactic shock.

Allergol Int 2019 Jan 7;68(1):119-121. Epub 2018 Aug 7.

Mastocytosis National Reference Center (CEREMAST), Department of Dermatology, Toulouse University Hospital, Paul Sabatier University, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.alit.2018.07.003DOI Listing
January 2019

Inflammatory disorders associated with trisomy 8-myelodysplastic syndromes: French retrospective case-control study.

Eur J Haematol 2019 Jan 14;102(1):63-69. Epub 2018 Nov 14.

Department of Internal Medicine, Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Antoine, Paris, France.

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http://dx.doi.org/10.1111/ejh.13174DOI Listing
January 2019

A Single-Tube, EuroClonality-Inspired, TRG Clonality Multiplex PCR Aids Management of Patients with Enteropathic Diseases, including from Formaldehyde-Fixed, Paraffin-Embedded Tissues.

J Mol Diagn 2019 Jan 28;21(1):111-122. Epub 2018 Sep 28.

Hematology Laboratory, Necker-Enfants Malades Hosptial and Paris Descartes, Sorbonne Paris Cité University, Paris, France; Hematology Laboratory, Hôpital Necker-Enfants Malades, Assistance Publique des Hôpitaux de Paris, Paris, France; INSERM UMR1151 and Institut Necker-Enfants Malades, Paris, France; Centre national Expert des Lymphomes Associés à la maladie Coeliaque, Hôpital Necker-Enfants Malades, Assistance Publique des Hôpitaux de Paris, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2018.08.006DOI Listing
January 2019

Progressive Multifocal Leukoencephalopathy in Primary Immunodeficiencies.

J Clin Immunol 2019 01 14;39(1):55-64. Epub 2018 Dec 14.

Department of Haematology, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, France et Université Paris Descartes, 149 rue de Sèvres, 75015, Paris, France.

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http://dx.doi.org/10.1007/s10875-018-0578-8DOI Listing
January 2019

Gain of affinity for VEGF165 binding within the VEGFR2/NRP1 cellular complex detected by an HTRF-based binding assay.

Biochem Pharmacol 2018 12 17;158:45-59. Epub 2018 Sep 17.

Institut Cochin, Inserm U1016, CNRS UMR 8104, University Paris Descartes, University Sorbonne Paris Cité, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2018.09.014DOI Listing
December 2018

Hydroxychloroquine as a novel therapeutic approach in mast cell activation diseases.

Clin Immunol 2018 09 10;194:75-79. Epub 2018 Jul 10.

Inserm, U1037, Centre de Recherche en Cancérologie de Toulouse (CRCT), Toulouse F-31037, France; Paul Sabatier University, Mastocytosis National Reference Center (CEREMAST), Department of Dermatology, Toulouse University and CHU, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2018.07.004DOI Listing
September 2018

Human CD4- invariant NKT lymphocytes regulate graft versus host disease.

Oncoimmunology 2018 23;7(11):e1470735. Epub 2018 Aug 23.

Département d'Hématologie, Institut Imagine, UMR 8147 Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implications, Paris, France.

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https://www.tandfonline.com/doi/full/10.1080/2162402X.2018.1
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http://dx.doi.org/10.1080/2162402X.2018.1470735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204997PMC
August 2018

Clinical Signs and Blood Test Results Among Humans Infected With Zoonotic Simian Foamy Virus: A Case-Control Study.

J Infect Dis 2018 06;218(1):144-151

Unité d'épidémiologie et Physiopathologie des Virus Oncogènes, Institut Pasteur, Paris, France.

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http://dx.doi.org/10.1093/infdis/jiy181DOI Listing
June 2018

Extrahepatic cancers and chronic HCV infection.

Nat Rev Gastroenterol Hepatol 2018 05 17;15(5):283-290. Epub 2018 Jan 17.

Service d'Hématologie, Hôpital Necker, 147 Rue de Sèvres, 75015 Paris Cedex 15, France.

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http://dx.doi.org/10.1038/nrgastro.2017.172DOI Listing
May 2018

Fluorescence Exclusion: A Simple Method to Assess Projected Surface, Volume and Morphology of Red Blood Cells Stored in Blood Bank.

Front Med (Lausanne) 2018 30;5:164. Epub 2018 May 30.

Biologie Intégrée du Globule Rouge UMR_S1134, Institut National de la Santé et de la Recherche Médicale, Université Paris Diderot, Sorbonne Paris Cité, Université de La Réunion, Université des Antilles, Paris, France.

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http://dx.doi.org/10.3389/fmed.2018.00164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989133PMC
May 2018

Survival benefit of mantle cell lymphoma patients enrolled in clinical trials; a joint study from the LYSA group and French cancer registries.

J Cancer Res Clin Oncol 2018 Apr 11;144(4):629-635. Epub 2017 Oct 11.

Registre des hémopathies malignes de Côte d'Or, Faculté des Sciences de Santé, Inserm UMR 1231, Université de Bourgogne F-Comté, 7 Bd Jeanne d'Arc, 21079, Dijon Cedex, France.

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http://dx.doi.org/10.1007/s00432-017-2529-9DOI Listing
April 2018

Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia.

N Engl J Med 2018 04;378(16):1479-1493

From the Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago (A.A.T., M.K.); University of California, San Francisco, Benioff Children's Hospital, Oakland (M.C.W., E.V.), Lucile Salter Packard Children's Hospital at Stanford, Palo Alto (S.S.), and David Geffen School of Medicine, University of California, Los Angeles, Los Angeles (G.J.S.) - all in California; Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia (J.K., D.T.T.); Centenary Institute (J.E.J.R.), University of Sydney, Sydney Medical School (J.E.J.R., P.J.H.), and Royal Prince Alfred Hospital (J.E.J.R., P.J.H.), Camperdown, NSW, Australia; Hôpital Universitaire Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris (J.-A.R., E.M., D.M., F.L., P.B., A.M., L.C., J.-S.D., F.S., F.M., V.B., C.B., O.H., M.D.M., S.B., M.C.), Groupe Hospitalier Universitaire Ouest (J.-A.R., A.M., L.C., M.C.), IMAGINE Institute (E.M., M.S., D.M., M.C.), Université Paris Descartes (M.S., C. Poirot, S.H.-B.-A.), Université Paris Diderot (H.P., T.L.), Pierre et Marie Curie University (C. Poirot), and Hôpital Cochin (J.-F.M.), Paris, CEA University Paris-Sud, Institute of Emerging Diseases and Innovative Therapies, Fontenay-aux-Roses (E.P., Y.B., S.C., P.L.), Hôpital Louis-Mourier, Colombes (H.P., T.L.), Centre Hospitalier Intercommunal de Créteil, Créteil (C. Pondarré), and Hôpital Bicêtre, Le Kremlin-Bicêtre (S.H.-B.-A.) - all in France; Bluebird Bio, Cambridge (J.-A.R., S.S., G.V., O.N., R.W.R., D.D., A.P., L.S., M.A.), and Harvard Medical School, Brigham and Women's Hospital, Boston (P.L.) - both in Massachusetts; Ramathibodi Hospital, Mahidol University, Bangkok, Thailand (S.H., U.A., P.L.); and the National Center for Tumor Diseases-German Cancer Research Center, Heidelberg, Germany (C.K.).

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http://dx.doi.org/10.1056/NEJMoa1705342DOI Listing
April 2018

Pediatric-onset Evans syndrome: Heterogeneous presentation and high frequency of monogenic disorders including LRBA and CTLA4 mutations.

Clin Immunol 2018 03 10;188:52-57. Epub 2018 Jan 10.

INSERM UMR 1163, Laboratory of Immunogenetics of pediatric autoimmune diseases, Paris, France; Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France; Pediatric immuno-hematology and rhumatology unit, RAISE reference centre for pediatric inflammatory rheumatic diseases and systemic autoimmune diseases, Necker-Enfants Malades University Hospital, Assistance publique - Hôpitaux de Paris, France.

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http://dx.doi.org/10.1016/j.clim.2017.12.009DOI Listing
March 2018

Overview of Targeted Therapies for Adult T-Cell Leukemia/Lymphoma.

Methods Mol Biol 2017 ;1582:197-216

Faculty of Medicine, Department of Anatomy, Cell Biology and Physiology, Americain University of Beirut, 113-6044, Beirut, Lebanon.

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http://link.springer.com/10.1007/978-1-4939-6872-5_15
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http://dx.doi.org/10.1007/978-1-4939-6872-5_15DOI Listing
February 2018

APN/CD13 is over-expressed by Psoriatic fibroblasts and is modulated by CGRP and IL-4 but not by retinoic acid treatment.

J Cell Physiol 2018 Feb 23;233(2):958-967. Epub 2017 May 23.

Laboratory of Cellular and Molecular Basis of Normal Hematopoiesis and Hematological Disorders, INSERM UMR 1163, Paris, France.

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http://dx.doi.org/10.1002/jcp.25941DOI Listing
February 2018

NRPa-308, a new neuropilin-1 antagonist, exerts in vitro anti-angiogenic and anti-proliferative effects and in vivo anti-cancer effects in a mouse xenograft model.

Cancer Lett 2018 02 28;414:88-98. Epub 2017 Oct 28.

INSERM U648, Laboratory of Molecular and Cellular Pharmacochemistry, Université Paris Descartes, Sorbonne Paris Cité, UFR Biomédicale des Saints Pères, 45 rue des Saints Pères, 75270, Paris cedex 06, France; Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques (LCBPT), UMR 8601 CNRS, Université Paris Descartes, Sorbonne Paris Cité, UFR Biomédicale des Saints Pères, 45 rue des Saints Pères, 75270, Paris cedex 06, France; Université Côte d'Azur, CNRS, Institut de Chimie de Nice UMR 7272, 06108, Nice, France. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.10.039DOI Listing
February 2018

Induction of autophagy and autophagy-dependent apoptosis in diffuse large B-cell lymphoma by a new antimalarial artemisinin derivative, SM1044.

Cancer Med 2018 02 26;7(2):380-396. Epub 2017 Dec 26.

State Key Laboratory for Medical Genomics, Department of Hematology, Shanghai Institute of Hematology, Collaborative Innovation Center of Systems Biomedicine, Pôle Sino-Français des Sciences du Vivant et Genomique, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1002/cam4.1276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806110PMC
February 2018

Impaired Transferrin Receptor Palmitoylation and Recycling in Neurodegeneration with Brain Iron Accumulation.

Am J Hum Genet 2018 02;102(2):266-277

UMR 1163, Université Paris Descartes, Sorbonne Paris Cité, Institut IMAGINE, 24 Boulevard du Montparnasse, 75015 Paris, France; Laboratory of Excellence GR-Ex, Institut IMAGINE, 24 Boulevard du Montparnasse, 75015 Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183000
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http://dx.doi.org/10.1016/j.ajhg.2018.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985451PMC
February 2018

A Review of New Findings in Adult T-cell Leukemia-Lymphoma: A Focus on Current and Emerging Treatment Strategies.

Adv Ther 2018 02 6;35(2):135-152. Epub 2018 Feb 6.

Department of Hematology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1007/s12325-018-0658-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818559PMC
February 2018

Hepatitis E virus-induced primary cutaneous CD30(+) T cell lymphoproliferative disorder.

J Hepatol 2017 12 30;67(6):1334-1339. Epub 2017 Aug 30.

Université Paris Descartes-Sorbonne Paris Cité, Paris, France; Institut National de la Santé et de la Recherche Médicale Unité 1163, Centre National de la Recherche Scientifique, Equipes de Recherche Labellisées 8254, Institut Imagine, Paris, France; Assistance Publique-Hopitaux de Paris (AP-HP), Hôpital Necker - Enfants Malades, Haematology Service, Paris, France.

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http://dx.doi.org/10.1016/j.jhep.2017.08.011DOI Listing
December 2017

Prevalence and risk factors for fragility fracture in systemic mastocytosis.

Bone 2017 Dec 14;105:219-225. Epub 2017 Sep 14.

Department of Dermatology, Mastocytosis Expert Center of Midi-Pyrénées, Paul Sabatier University, Toulouse University Hospital, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2017.09.005DOI Listing
December 2017

The role of 5-HT receptors in mitral valvulopathy: bone marrow mobilization of endothelial progenitors.

Br J Pharmacol 2017 Nov 15;174(22):4123-4139. Epub 2017 Oct 15.

Laboratoire de Neurobiologie et Pharmacologie Cardiovasculaire (EA7296), Faculté de Médecine, Fédération de Médecine Translationnelle, Université et Centre Hospitalier de Strasbourg, Strasbourg, France.

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http://doi.wiley.com/10.1111/bph.13981
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http://dx.doi.org/10.1111/bph.13981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680644PMC
November 2017

Hepatitis C virus - Associated marginal zone lymphoma.

Best Pract Res Clin Haematol 2017 Mar - Jun;30(1-2):41-49. Epub 2017 Feb 11.

Department of Hematology, Hôpital Pitié-Salpêtrière, AP-HP, Paris, France; UPMC Univ Paris 06, UMRS-1138, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.beha.2017.02.001DOI Listing
October 2017

Helicobacter bilis-Associated Suppurative Cholangitis in a Patient with X-Linked Agammaglobulinemia.

J Clin Immunol 2017 Oct 31;37(7):727-731. Epub 2017 Aug 31.

Université Paris Descartes - Sorbonne Paris Cité, Service de Maladies infectieuses et Tropicales, Hôpital Necker-Enfants Malades, Centre d'Infectiologie Necker-Pasteur, Assistance Publique - Hôpitaux de Paris, Paris, France.

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http://dx.doi.org/10.1007/s10875-017-0437-zDOI Listing
October 2017

Rituximab after Autologous Stem-Cell Transplantation in Mantle-Cell Lymphoma.

N Engl J Med 2017 09;377(13):1250-1260

From Service d'Hématologie Clinique (S.L.G., T.G.), Service d'Anatomopathologie (A.M.), and Service d'Hématologie Biologique (M.C.B.), Hôtel-Dieu Centre Hospitalier Universitaire (CHU) de Nantes, and Centre de Recherche en Cancérologie et Immunologie (S.L.G., M.C.B.) and Faculté de Médecine (S.L.G.), Université de Nantes, Nantes, Hemato-Oncologie, Assistance Publique-Hôpitaux de Paris (APHP), Hôpital Saint-Louis, Université Diderot Sorbonne Paris-Cité (C.T.), Université Descartes (C.T.), Département d'Hématologie, Faculté de Médecine, Université Paris-Sud (V.R.), Département d'Anatomopathologie (D.C.) and Département d'Hématologie (O.H.), Necker Hospital, APHP, Sorbonne Paris-Cité, and INSERM Unité 1163 et Centre National de la Recherche Scientifique (CNRS) Équipe de Recherche Labellisée 8654, Imagine Institute (O.H.), Paris, Département d'Hématologie, Institut Universitaire du Cancer-Oncopole de Toulouse, Toulouse (L.O.), Service d'Hématologie Clinique et Thérapie Cellulaire, CHU de Bordeaux, Bordeaux (K.B.), Service d'Hématologie et Thérapie Cellulaire, CHU de Tours, Tours (C.D.), Service d'Hématologie, CHU d'Amiens, Amiens (G.D.), INSERM, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif (V.R.), Département d'Hématologie, CHU de Nancy, Nancy (P.F.), INSERM Unité 954, Vandoeuvre (P.F.), Service d'Hématologie Clinique, CHU de Dijon, and INSERM Unité Mixte de Recherche 1231, Dijon (O.C.), Service d'Hématologie, Centre Hospitalier d'Avignon, Avignon (H.Z.), Lymphoid Malignancies Unit, Hôpital Henri Mondor, APHP, Créteil (C.H.), Service d'Hématologie du Centre Hospitalier de Vendée, La Roche-sur-Yon (H.M.), Service Hématologie Clinique (R.H.) and Département d'Hématologie (T.L.), CHU de Rennes, INSERM Unité 917 (R.H.), and INSERM Unité 1236 (T.L.), Rennes, Département d'Hematology, Centre Henri-Becquerel et Université de Normandie Unité 1245, Rouen (F.J., H.T.), Service d'Hématologie Clinique Adulte et de Thérapie Cellulaire, CHU de Clermont-Ferrand et Université Clermont Auvergne, Clermont-Ferrand (O.T.), Service d'Hématologie, Clinique Victor Hugo, Le Mans (K.L.D.), Department of Hematology, Université de Lille, Groupe de Recherche sur les Formes Injectables et les Technologies Associées, and CHU de Lille, Lille (F.M.), Département d'Hématologie Clinique, CHU de Montpellier, CNRS UMR 5235, Montpellier (G.C.), Service d'Oncologie et d'Hématologie, Hôpitaux Universitaires de Strasbourg, Strasbourg (L.-M.F.), INSERM 1209, CNRS UMR 5309, Faculté de Médecine, Université Grenoble Alpes (M.C., R.G.), Institute for Advanced Biosciences (M.C.), and Laboratoire de Génétique Onco-hématologie (M.C.) and Faculté de Médecine (R.G.), CHU de Grenoble Alpes, Grenoble, Service d'Hématologie, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre-Bénite (G.S.), and Université Claude Bernard Lyon 1 and Cancer Research Center of Lyon, INSERM 1052 CNRS 5286 Lyon, Lyon (G.S.) - all in France; and Département d'Hématologie, Cliniques Universitaires Saint-Luc-Université Catholique de Louvain, Brussels (E.V.D.N.).

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http://dx.doi.org/10.1056/NEJMoa1701769DOI Listing
September 2017

A somatic mosaicism in the G6PD gene inducing a late onset chronic non-spherocytic hemolytic anemia.

Am J Hematol 2017 Aug 1;92(8):E153-E155. Epub 2017 Jun 1.

Service d'Hématologie Biologique, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1002/ajh.24760DOI Listing
August 2017

Targeted Treatment Options in Mastocytosis.

Front Med (Lausanne) 2017 20;4:110. Epub 2017 Jul 20.

French Reference Center for Mastocytosis (CEREMAST), Department of Hematology, Necker Children's Hospital, APHP, Paris, France.

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http://dx.doi.org/10.3389/fmed.2017.00110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517467PMC
July 2017

Antioxidant and Membrane Binding Properties of Serotonin Protect Lipids from Oxidation.

Biophys J 2017 May;112(9):1863-1873

Université Sorbonne Paris Cité, Université Paris Diderot, INSERM, Unité Biologie Intégrée du Globule Rouge UMR-S1134, Institut National de la Transfusion Sanguine, Laboratoire d'Excellence GR-Ex, Paris, France; Université Sorbonne Paris Cité, Université Paris Descartes, INSERM, CNRS, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implications U1163, Institut Imagine, Laboratoire d'Excellence GR-Ex, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00063495173038
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http://dx.doi.org/10.1016/j.bpj.2017.03.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425403PMC
May 2017

Spherocytic shift of red blood cells during storage provides a quantitative whole cell-based marker of the storage lesion.

Transfusion 2017 04 1;57(4):1007-1018. Epub 2017 Feb 1.

Université Sorbonne Paris Cité, Université Paris Diderot, Inserm, INTS, Unité Biologie Intégrée du Globule Rouge.

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http://dx.doi.org/10.1111/trf.14015DOI Listing
April 2017

Randomized Phase II Study of Clofarabine-Based Consolidation for Younger Adults With Acute Myeloid Leukemia in First Remission.

J Clin Oncol 2017 Apr 21;35(11):1223-1230. Epub 2017 Feb 21.

Xavier Thomas, Lyon-Sud University Hospital, Pierre Bénite; Stéphane de Botton, Gustave-Roussy Cancer Institute, Villejuif; Sylvie Chevret, Emmanuel Raffoux, and Hervé Dombret, Paris Saint-Louis University Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), University Paris Diderot; Olivier Hermine, Paris Necker University Hospital, AP-HP, University Paris Descartes; Karine Celli-Lebras, Acute Leukemia French Association Coordination Office, Paris Saint-Louis University Hospital, Paris; Denis Caillot, Dijon University Hospital, Dijon; Emilie Lemasle, Henri-Becquerel Cancer Center, Rouen; Jean-Pierre Marolleau, Amiens University Hospital, Amiens; Céline Berthon, Claude Huriez University Hospital; Claude Preudhomme, University of Lille, Claude Huriez University Hospital, Institut National de la Santé et de la Recherche Médicale UMR-S 1172, Jean-Pierre Aubert Research Institute, Lille; Arnaud Pigneux, Bordeaux Haut-Leveque University Hospital, Pessac; Norbert Vey, Paoli-Calmette Cancer Institute, Marseille; Oumedaly Reman, George-Clémenceau University Hospital, Caen; Marc Simon, Valenciennes Hospital, Valenciennes; Christian Recher, Toulouse Cancer University Institute, Toulouse; Jean-Yves Cahn, Grenoble University Hospital, Grenoble; Sylvie Castaigne and Christine Terré, Versailles University Hospital, Versailles-Saint Quentin University, Le Chesnay; and Norbert Ifrah, Angers University Hospital, Angers, France.

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http://dx.doi.org/10.1200/JCO.2016.70.4551DOI Listing
April 2017

A major turning point in NK/T-cell lymphoma?

Blood 2017 04;129(17):2342-2343

ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS.

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http://dx.doi.org/10.1182/blood-2017-03-769075DOI Listing
April 2017

ALS Clinical Trials Review: 20 Years of Failure. Are We Any Closer to Registering a New Treatment?

Front Aging Neurosci 2017 22;9:68. Epub 2017 Mar 22.

AB ScienceParis, France; Imagine Institute, Necker HospitalParis, France; INSERM, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implications, UMR 1163Paris, France; Imagine Institute, Paris Descartes-Sorbonne Paris Cité UniversityParis, France; CNRS, ERL 8254Paris, France; Laboratory of Excellence GR-ExParis, France; Equipe Labélisée par la Ligue Nationale Contre le CancerParis, France; Department of Hematology, Necker HospitalParis, France.

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http://journal.frontiersin.org/article/10.3389/fnagi.2017.00
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http://dx.doi.org/10.3389/fnagi.2017.00068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360725PMC
March 2017