Olivier Bensaude

Olivier Bensaude

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Olivier Bensaude

Olivier Bensaude

Publications by authors named "Olivier Bensaude"

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Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.

Nucleic Acids Res 2020 Jun;48(10):5670-5683

Institut de Biologie de l'Ecole Normale Supérieure (IBENS), Ecole Normale Supérieure, CNRS, INSERM, PSL Research University, 46 rue d'Ulm, 75005 Paris, France.

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http://dx.doi.org/10.1093/nar/gkaa267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261170PMC
June 2020

Hexim1, an RNA-controlled protein hub.

Transcription 2018 23;9(4):262-271. Epub 2018 Feb 23.

a IBENS , Ecole Normale Supérieure UMR CNRS 8107, UA INSERM 1024 , 46 rue d'Ulm Paris Cedex France.

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https://www.tandfonline.com/doi/full/10.1080/21541264.2018.1
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http://dx.doi.org/10.1080/21541264.2018.1429836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104690PMC
October 2018

HEXIM1 Has Different Functions within Different RNA-Protein Complexes.

Authors:
Olivier Bensaude

Mol Cell 2017 Aug;67(3):357-359

IBENS-CNRS UMR 8197-INSERM U1024-Ecole Normale Supérieure 46, Rue d'Ulm, Cedex 05, 75230 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.07.021DOI Listing
August 2017

An evolutionary conserved Hexim1 peptide binds to the Cdk9 catalytic site to inhibit P-TEFb.

Proc Natl Acad Sci U S A 2016 Nov 25;113(45):12721-12726. Epub 2016 Oct 25.

Ecole Normale Supérieure, Institut de Biologie de l'Ecole Normale Supérieure (IBENS), CNRS UMR 8197, INSERM U-1024, Université de Recherche Paris Sciences et Lettres, F-75230 Paris Cedex 05, France;

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http://dx.doi.org/10.1073/pnas.1612331113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111705PMC
November 2016

A single point mutation in cyclin T1 eliminates binding to Hexim1, Cdk9 and RNA but not to AFF4 and enforces repression of HIV transcription.

Retrovirology 2014 Jul 1;11:51. Epub 2014 Jul 1.

The Shraga Segal Department of Microbiology, Immunology and Genetics Faculty of Health Sciences, Ben-Gurion University of the Negev, P,O, Box 653, Beer-Sheva 84105, ISRAEL.

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http://dx.doi.org/10.1186/1742-4690-11-51DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226998PMC
July 2014

Genetically encoding a light switch in an ionotropic glutamate receptor reveals subunit-specific interfaces.

Proc Natl Acad Sci U S A 2014 Apr 8;111(16):6081-6. Epub 2014 Apr 8.

Ecole Normale Supérieure, Institut de Biologie de l' Ecole Normale Supérieure, Institut National de la Santé et de la Recherche Médicale U1024, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8197, F-75005 Paris, France.

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http://www.pnas.org/content/suppl/2014/04/08/1318808111.DCSu
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http://www.pnas.org/cgi/doi/10.1073/pnas.1318808111
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http://dx.doi.org/10.1073/pnas.1318808111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000820PMC
April 2014

An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription.

Proc Natl Acad Sci U S A 2014 Jan 16;111(4):1491-6. Epub 2014 Jan 16.

Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115.

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http://dx.doi.org/10.1073/pnas.1323535111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910647PMC
January 2014

CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo.

Nucleic Acids Res 2013 Feb 28;41(3):1591-603. Epub 2012 Dec 28.

Ecole Normale Supérieure, IBENS, 46, rue d'Ulm, Paris 75005, France.

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http://dx.doi.org/10.1093/nar/gks1327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561981PMC
February 2013

Inhibiting eukaryotic transcription: Which compound to choose? How to evaluate its activity?

Authors:
Olivier Bensaude

Transcription 2011 May;2(3):103-108

IBENS; UMR CNRS 8197; UA INSERM 1024; Paris, France.

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http://dx.doi.org/10.4161/trns.2.3.16172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173647PMC
May 2011

Characterization of MRP RNA-protein interactions within the perinucleolar compartment.

Mol Biol Cell 2011 Mar 13;22(6):858-67. Epub 2011 Jan 13.

Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1091/mbc.E10-09-0768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057709PMC
March 2011

Splicing-independent recruitment of U1 snRNP to a transcription unit in living cells.

J Cell Sci 2010 Jun;123(Pt 12):2085-93

Ecole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, Paris, France.

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http://dx.doi.org/10.1242/jcs.061358DOI Listing
June 2010

7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor.

RNA Biol 2009 Apr-Jun;6(2):122-8. Epub 2009 Apr 6.

Ecole Normale Supérieure, CNRS UMR 8541 Régulation de l'Expression Génétique, Paris, France.

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http://dx.doi.org/10.4161/rna.6.2.8115DOI Listing
February 2010

Evolution of 7SK RNA and its protein partners in metazoa.

Mol Biol Evol 2009 Dec 4;26(12):2821-30. Epub 2009 Sep 4.

Bioinformatics Group, Department of Computer Science, and Interdisciplinary Center for Bioinformatics, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1093/molbev/msp198DOI Listing
December 2009

Ubiquitination of HEXIM1 by HDM2.

Cell Cycle 2009 Jul;8(14):2247-54

Expression Engineering Group, Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Centros, Singapore.

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http://dx.doi.org/10.4161/cc.8.14.9015DOI Listing
July 2009

RNA-driven cyclin-dependent kinase regulation: when CDK9/cyclin T subunits of P-TEFb meet their ribonucleoprotein partners.

Biotechnol J 2008 Aug;3(8):1022-32

Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.

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http://doi.wiley.com/10.1002/biot.200800104
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http://dx.doi.org/10.1002/biot.200800104DOI Listing
August 2008

Non-coding RNAs regulating the transcriptional machinery.

Biol Cell 2008 Feb;100(2):83-95

CNRS UMR 8541, Ecole Normale Supérieure, 46 rue d'Ulm, Paris, Cedex 05, France.

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http://dx.doi.org/10.1042/BC20070090DOI Listing
February 2008

The transcription-dependent dissociation of P-TEFb-HEXIM1-7SK RNA relies upon formation of hnRNP-7SK RNA complexes.

Mol Cell Biol 2007 Oct 20;27(20):6996-7006. Epub 2007 Aug 20.

UMR 8541 CNRS, Ecole Normale Supérieure, 46 rue d'Ulm, 75230 Paris Cedex 05, France.

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http://dx.doi.org/10.1128/MCB.00975-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168891PMC
October 2007

Increased HEXIM1 expression during erythroleukemia and neuroblastoma cell differentiation.

J Cell Physiol 2006 Mar;206(3):603-10

Department of Structural and Functional Biology, University of Naples Federico II, Naples, Italy.

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http://dx.doi.org/10.1002/jcp.20502DOI Listing
March 2006

The hyperfluidization of mammalian cell membranes acts as a signal to initiate the heat shock protein response.

FEBS J 2005 Dec;272(23):6077-86

Institute of Biochemistry, Biological Research Centre, Hungarian Academy of Sciences, Szeged, Hungary.

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http://dx.doi.org/10.1111/j.1742-4658.2005.04999.xDOI Listing
December 2005

Transcription-dependent association of multiple positive transcription elongation factor units to a HEXIM multimer.

J Biol Chem 2005 Aug 30;280(34):30619-29. Epub 2005 Jun 30.

Unite Mixte de Recherche 8541 CNRS, Ecole Normale Supérieure, Laboratoire de Régulation de l'Expression Génétique, 75230 Paris Cedex 05, France.

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http://dx.doi.org/10.1074/jbc.M502471200DOI Listing
August 2005

Inhibition of Tat activity by the HEXIM1 protein.

Retrovirology 2005 Jul 2;2:42. Epub 2005 Jul 2.

Department of Structural and Functional Biology, University of Naples Federico II, Naples, Italy.

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http://retrovirology.biomedcentral.com/articles/10.1186/1742
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http://dx.doi.org/10.1186/1742-4690-2-42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1183248PMC
July 2005

Dephosphorylation of RNA polymerase II by CTD-phosphatase FCP1 is inhibited by phospho-CTD associating proteins.

J Mol Biol 2004 Jan;335(2):415-24

Génétique Moléculaire, UMR 8541 CNRS, Ecole Normale Supérieure, 46 rue d'Ulm, 75230 Paris Cedex 05, France.

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http://dx.doi.org/10.1016/j.jmb.2003.10.036DOI Listing
January 2004

The last CTD repeat of the mammalian RNA polymerase II large subunit is important for its stability.

Nucleic Acids Res 2004 2;32(1):35-44. Epub 2004 Jan 2.

Institute of Clinical Molecular Biology and Tumour Genetics, GSF Research Center for Environment and Health, Marchioninistr. 25, D-81377 Munich, Germany.

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http://dx.doi.org/10.1093/nar/gkh172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC373282PMC
January 2004

[Protein synthesis starts in the nucleus].

Authors:
Olivier Bensaude

Med Sci (Paris) 2003 Aug-Sep;19(8-9):775-8

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http://dx.doi.org/10.1051/medsci/20031989775DOI Listing
December 2003

Investigating RNA polymerase II carboxyl-terminal domain (CTD) phosphorylation.

Eur J Biochem 2003 Oct;270(19):3859-70

Génétique Moléculaire, UMR 8541 CNRS, Ecole Normale Supérieure, Paris, France.

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http://dx.doi.org/10.1046/j.1432-1033.2003.03794.xDOI Listing
October 2003

MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner.

Mol Cell Biol 2003 Jul;23(14):4859-69

UMR 8541 CNRS, Ecole Normale Supérieure, Laboratoire de Régulation de l'Expression Génétique, 75230 Paris Cedex 05, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC162212PMC
http://dx.doi.org/10.1128/mcb.23.14.4859-4869.2003DOI Listing
July 2003

Heat shock protein coinducers with no effect on protein denaturation specifically modulate the membrane lipid phase.

Proc Natl Acad Sci U S A 2003 Mar 3;100(6):3131-6. Epub 2003 Mar 3.

Institute of Biochemistry, Biological Research Centre, Hungarian Academy of Sciences, P.O. Box 521, H-6701 Szeged, Hungary.

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http://dx.doi.org/10.1073/pnas.0438003100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC152258PMC
March 2003

FCP1 phosphorylation by casein kinase 2 enhances binding to TFIIF and RNA polymerase II carboxyl-terminal domain phosphatase activity.

J Biol Chem 2002 Sep 22;277(39):36061-7. Epub 2002 Jul 22.

UMR 8541 CNRS, Génétique Moléculaire, Ecole Normale Supérieure, 46 rue d'Ulm, 75230 Paris Cedex 05, France.

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http://dx.doi.org/10.1074/jbc.M205192200DOI Listing
September 2002