Publications by authors named "Olivier Ayrault"

46Publications

Introduction. Pediatric brain tumor.

Neurosurg Focus 2020 01;48(1):E1

5Department of Neurology, Sandler Neuroscience Center, University of California, San Francisco, California.

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http://dx.doi.org/10.3171/2019.10.FOCUS19799DOI Listing
January 2020

Medulloblastomics revisited: biological and clinical insights from thousands of patients.

Nat Rev Cancer 2020 01 9;20(1):42-56. Epub 2019 Dec 9.

Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1038/s41568-019-0223-8DOI Listing
January 2020

Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma.

Nature 2019 10 9;574(7780):707-711. Epub 2019 Oct 9.

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/s41586-019-1650-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141958PMC
October 2019

SHH medulloblastoma in a young adult with a TCF4 germline pathogenic variation.

Acta Neuropathol 2019 04 8;137(4):675-678. Epub 2019 Mar 8.

Pediatric Oncology Department, SIREDO Oncology Centre (Care, Innovation, Research in Pediatric, Adolescent and Young Adults Oncology), Institut Curie, 26, rue d'Ulm, 75248, Paris Cedex 05, France.

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http://dx.doi.org/10.1007/s00401-019-01983-4DOI Listing
April 2019

Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation.

Dev Cell 2019 01;48(2):184-199.e5

Institut Curie, PSL Research University, CNRS UMR 3347, INSERM U1021, Orsay 91405, France; Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay 91405, France. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2018.12.017DOI Listing
January 2019

NRL and CRX Define Photoreceptor Identity and Reveal Subgroup-Specific Dependencies in Medulloblastoma.

Cancer Cell 2018 03;33(3):435-449.e6

Institut Curie - Recherche, Laboratoire 110, Centre Universitaire, Orsay Cedex 91405, France; INSERM U1021, Centre Universitaire, Orsay 91405, France; CNRS UMR 3347, Centre Universitaire, Orsay 91405, France; Université Paris Sud-11, 91405 Orsay, France; PSL Research University, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15356108183005
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http://dx.doi.org/10.1016/j.ccell.2018.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368680PMC
March 2018

Divergent clonal selection dominates medulloblastoma at recurrence.

Authors:
A Sorana Morrissy Livia Garzia David J H Shih Scott Zuyderduyn Xi Huang Patryk Skowron Marc Remke Florence M G Cavalli Vijay Ramaswamy Patricia E Lindsay Salomeh Jelveh Laura K Donovan Xin Wang Betty Luu Kory Zayne Yisu Li Chelsea Mayoh Nina Thiessen Eloi Mercier Karen L Mungall Yusanne Ma Kane Tse Thomas Zeng Karey Shumansky Andrew J L Roth Sohrab Shah Hamza Farooq Noriyuki Kijima Borja L Holgado John J Y Lee Stuart Matan-Lithwick Jessica Liu Stephen C Mack Alex Manno K A Michealraj Carolina Nor John Peacock Lei Qin Juri Reimand Adi Rolider Yuan Y Thompson Xiaochong Wu Trevor Pugh Adrian Ally Mikhail Bilenky Yaron S N Butterfield Rebecca Carlsen Young Cheng Eric Chuah Richard D Corbett Noreen Dhalla An He Darlene Lee Haiyan I Li William Long Michael Mayo Patrick Plettner Jenny Q Qian Jacqueline E Schein Angela Tam Tina Wong Inanc Birol Yongjun Zhao Claudia C Faria José Pimentel Sofia Nunes Tarek Shalaby Michael Grotzer Ian F Pollack Ronald L Hamilton Xiao-Nan Li Anne E Bendel Daniel W Fults Andrew W Walter Toshihiro Kumabe Teiji Tominaga V Peter Collins Yoon-Jae Cho Caitlin Hoffman David Lyden Jeffrey H Wisoff James H Garvin Duncan S Stearns Luca Massimi Ulrich Schüller Jaroslav Sterba Karel Zitterbart Stephanie Puget Olivier Ayrault Sandra E Dunn Daniela P C Tirapelli Carlos G Carlotti Helen Wheeler Andrew R Hallahan Wendy Ingram Tobey J MacDonald Jeffrey J Olson Erwin G Van Meir Ji-Yeoun Lee Kyu-Chang Wang Seung-Ki Kim Byung-Kyu Cho Torsten Pietsch Gudrun Fleischhack Stephan Tippelt Young Shin Ra Simon Bailey Janet C Lindsey Steven C Clifford Charles G Eberhart Michael K Cooper Roger J Packer Maura Massimino Maria Luisa Garre Ute Bartels Uri Tabori Cynthia E Hawkins Peter Dirks Eric Bouffet James T Rutka Robert J Wechsler-Reya William A Weiss Lara S Collier Adam J Dupuy Andrey Korshunov David T W Jones Marcel Kool Paul A Northcott Stefan M Pfister David A Largaespada Andrew J Mungall Richard A Moore Nada Jabado Gary D Bader Steven J M Jones David Malkin Marco A Marra Michael D Taylor

Nature 2016 Jan 13;529(7586):351-7. Epub 2016 Jan 13.

Developmental &Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.

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http://dx.doi.org/10.1038/nature16478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936195PMC
January 2016

Insights into cerebellar development and medulloblastoma.

Bull Cancer 2016 Jan 11;103(1):30-40. Epub 2015 Dec 11.

Centre universitaire, institut Curie, CNRS UMR 3347, Inserm U1021, building 110, 91405 Orsay, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2015.11.002DOI Listing
January 2016

PML IV/ARF interaction enhances p53 SUMO-1 conjugation, activation, and senescence.

Proc Natl Acad Sci U S A 2015 Nov 2;112(46):14278-83. Epub 2015 Nov 2.

University Paris Diderot, Sorbonne Paris Cité, Hôpital St. Louis 1, Paris cedex 10, France; INSERM U944, Equipe Labellisée par la Ligue Nationale contre le Cancer, Institut Universitaire d'Hématologie, Hôpital St. Louis 1, Paris cedex 10, France; CNRS UMR 7212, Hôpital St. Louis 1, Paris cedex 10, France; Assistance Publique-Hôpitaux de Paris, Service de Biochimie, Hôpital St. Louis 1, Paris cedex 10, France; Collège de France, Chaire d'Oncologie Cellulaire et Moléculaire, 75005 Paris, France

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http://dx.doi.org/10.1073/pnas.1507540112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655504PMC
November 2015

Dicer Is Required for Normal Cerebellar Development and to Restrain Medulloblastoma Formation.

PLoS One 2015 19;10(6):e0129642. Epub 2015 Jun 19.

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129642PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474721PMC
April 2016

MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.

FASEB J 2015 May 30;29(5):1817-29. Epub 2015 Jan 30.

*Centre National de la Recherche Scientifique, Unité Mixte de Recherche-9197, Neuroscience Paris-Saclay Institute, Molecules Circuits Department, Signal Transduction and Developmental Neuropharmacology Team, Gif-sur-Yvette, France; Centre National de la Recherche Scientifique, Unité Mixte de Recherche-7200, Laboratoire d'Innovation Thérapeutique, Université de Strasbourg, Illkirch, France; Centre National de la Recherche Scientifique, Unité Mixte de Recherche-3306, Institut National de la Santé et de la Recherche Médicale U1005, Institut Curie, Centre Universitaire, Orsay, France; and Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Siena, Italy

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http://dx.doi.org/10.1096/fj.14-267849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415011PMC
May 2015

Role of the miR-17∼92 cluster family in cerebellar and medulloblastoma development.

Biol Open 2014 Jun 13;3(7):597-605. Epub 2014 Jun 13.

Department of Tumor Cell Biology, Danny Thomas Research Center, St Jude Children's Research Hospital, Memphis, TN 38105-3678, USA

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http://dx.doi.org/10.1242/bio.20146734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154296PMC
June 2014

Silencing of the miR-17~92 cluster family inhibits medulloblastoma progression.

Cancer Res 2013 Dec 21;73(23):7068-78. Epub 2013 Oct 21.

Authors' Affiliations: Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee; Santaris Pharma, Hørsholm; and Department of Haematology, Aalborg University Hospital, Copenhagen, Denmark.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-0927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857104PMC
December 2013

[Subtypes of medulloblastomas: distinct cellular origins].

Med Sci (Paris) 2012 Oct 12;28(10):805-9. Epub 2012 Oct 12.

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http://dx.doi.org/10.1051/medsci/20122810003DOI Listing
October 2012

Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells.

Cancer Res 2010 Jul 1;70(13):5618-27. Epub 2010 Jun 1.

Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896438PMC
July 2010

Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma.

Proc Natl Acad Sci U S A 2009 Oct 23;106(40):17037-42. Epub 2009 Sep 23.

Department of Genetics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1073/pnas.0902880106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761355PMC
October 2009

Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma.

Mol Cancer Res 2009 Jan;7(1):33-40

Department of Genetics and Tumor Cell Biology, Mail Stop no. 350, 262 Danny Thomas Place, Memphis, TN 38105-3678, USA.

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http://mcr.aacrjournals.org/lookup/doi/10.1158/1541-7786.MCR
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http://dx.doi.org/10.1158/1541-7786.MCR-08-0369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637533PMC
January 2009

Differential post-transcriptional regulation of two Ink4 proteins, p18 Ink4c and p19 Ink4d.

Cell Cycle 2008 Dec 13;7(23):3737-46. Epub 2008 Dec 13.

Department of Tumor Cell Biology and Genetics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628444PMC
http://dx.doi.org/10.4161/cc.7.23.7187DOI Listing
December 2008

Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development.

Genes Dev 2008 Mar;22(6):722-7

Departments of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1101/gad.1636408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275424PMC
March 2008

Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2.

Nat Struct Mol Biol 2008 Mar 10;15(3):280-7. Epub 2008 Feb 10.

Howard Hughes Medical Institute, St. Jude Children's Research Hospital, 332 North Lauderdale, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1038/nsmb.1387DOI Listing
March 2008

[The negative regulation of ribosome biogenesis: a new Arf-dependent pathway controlling cell proliferation?].

Med Sci (Paris) 2006 May;22(5):519-24

EA 3805, Equipe d'Oncologie Moléculaire, Pôle Biologie-Santé, 40, avenue du recteur Pineau, 86022 Poitiers Cedex, France.

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http://dx.doi.org/10.1051/medsci/2006225519DOI Listing
May 2006

Involvement of the transcriptional factor E2F1 in the regulation of the rRNA promoter.

Exp Cell Res 2006 Apr 28;312(7):1185-93. Epub 2006 Feb 28.

Laboratoire d'Oncologie Moléculaire, EA 3805, Pôle Biologie-Santé, 40, avenue du Recteur Pineau, 86022 Poitiers cedex, France.

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http://dx.doi.org/10.1016/j.yexcr.2006.01.027DOI Listing
April 2006

In vitro and in vivo analysis of the interaction between 5.8S rRNA and ARF protein reveal a new difference between murine p19ARF and human p14ARF.

Oncogene 2005 Apr;24(15):2580-4

EA 3805, Laboratoire d'Oncologie Moléculaire, Pôle Biologie-Santé, 40 avenue du Recteur Pineau, 86022 Poitiers Cedex, France.

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http://dx.doi.org/10.1038/sj.onc.1208457DOI Listing
April 2005

Developmental progression of immunoglobulin heavy chain diversity in sheep.

Vet Immunol Immunopathol 2005 Jan;103(1-2):31-51

Laboratoire d'Immunologie Moléculaire, Faculté des Sciences, EA 2224, IFR 59, Université de Poitiers, 40 Avenue du Recteur Pineau, 86022 Poitiers Cedex, France.

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http://dx.doi.org/10.1016/j.vetimm.2004.08.013DOI Listing
January 2005

Human Arf tumor suppressor specifically interacts with chromatin containing the promoter of rRNA genes.

Oncogene 2004 Oct;23(49):8097-104

Laboratoire d'Oncologie Moléculaire EA3805, Pôle Biologie-Santé. 40, avenue du recteur Pineau, 86022 Poitiers cedex, France.

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http://dx.doi.org/10.1038/sj.onc.1207968DOI Listing
October 2004