Oliver T Fackler

Oliver T Fackler

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Oliver T Fackler

Publications by authors named "Oliver T Fackler"

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SERINC5 Is an Unconventional HIV Restriction Factor That Is Upregulated during Myeloid Cell Differentiation.

J Innate Immun 2020 Jan 14:1-11. Epub 2020 Jan 14.

Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, Faculty of Medicine, LMU München, Munich, Germany.

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http://dx.doi.org/10.1159/000504888DOI Listing
January 2020

GPCR-induced calcium transients trigger nuclear actin assembly for chromatin dynamics.

Nat Commun 2019 11 21;10(1):5271. Epub 2019 Nov 21.

Institute of Experimental and Clinical Pharmacology and Toxicology, University of Freiburg, Albertstraße 25, 79104, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41467-019-13322-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872576PMC
November 2019

FAMoS: A Flexible and dynamic Algorithm for Model Selection to analyse complex systems dynamics.

PLoS Comput Biol 2019 08 16;15(8):e1007230. Epub 2019 Aug 16.

Center for Modelling and Simulation in the Biosciences, BioQuant-Center, Heidelberg University, Heidelberg, Germany.

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http://dx.plos.org/10.1371/journal.pcbi.1007230
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http://dx.doi.org/10.1371/journal.pcbi.1007230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697322PMC
August 2019

Experimental and computational analyses reveal that environmental restrictions shape HIV-1 spread in 3D cultures.

Nat Commun 2019 05 13;10(1):2144. Epub 2019 May 13.

Department of Infectious Diseases, Centre for Integrative Infectious Disease Research (CIID), Integrative Virology, University Hospital Heidelberg, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41467-019-09879-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514199PMC
May 2019

Intrinsic properties and plasma membrane trafficking route of Src family kinase SH4 domains sensitive to retargeting by HIV-1 Nef.

J Biol Chem 2018 05 27;293(20):7824-7840. Epub 2018 Mar 27.

From the Department of Infectious Diseases, Center for Integrative Infectious Disease Research (CIID), Integrative Virology, University Hospital Heidelberg, Im Neuenheimer Feld 344, 69120 Heidelberg, Germany

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http://dx.doi.org/10.1074/jbc.RA118.002794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961038PMC
May 2018

Tailored environments to study motile cells and pathogens.

Cell Microbiol 2018 03 29;20(3). Epub 2018 Jan 29.

Integrative Parasitology, Center for Infectious Diseases, Heidelberg University, Heidelberg, Germany.

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http://doi.wiley.com/10.1111/cmi.12820
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http://dx.doi.org/10.1111/cmi.12820DOI Listing
March 2018

Microstructured Blood Vessel Surrogates Reveal Structural Tropism of Motile Malaria Parasites.

Adv Healthc Mater 2017 Mar 24;6(6). Epub 2017 Jan 24.

Integrative Parasitology, Center for Infectious Diseases, Heidelberg University Hospital, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1002/adhm.201601178DOI Listing
March 2017

The Antagonism of HIV-1 Nef to SERINC5 Particle Infectivity Restriction Involves the Counteraction of Virion-Associated Pools of the Restriction Factor.

J Virol 2016 Dec 14;90(23):10915-10927. Epub 2016 Nov 14.

Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, Heidelberg, Germany

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http://dx.doi.org/10.1128/JVI.01246-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110172PMC
December 2016

D186/D190 is an allele-dependent determinant of HIV-1 Nef function.

Virology 2016 11 24;498:44-56. Epub 2016 Aug 24.

Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00426822163021
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http://dx.doi.org/10.1016/j.virol.2016.08.012DOI Listing
November 2016

HIV Nef- and Notch1-dependent Endocytosis of ADAM17 Induces Vesicular TNF Secretion in Chronic HIV Infection.

EBioMedicine 2016 Nov 19;13:294-304. Epub 2016 Oct 19.

Department of Dermatology, University Hospital Erlangen, Hartmannstr. 14, 91054 Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.10.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264432PMC
November 2016

HIV-1 Vpu Antagonizes CD317/Tetherin by Adaptor Protein-1-Mediated Exclusion from Virus Assembly Sites.

J Virol 2016 08 11;90(15):6709-6723. Epub 2016 Jul 11.

Department of Infectious Diseases, Integrative Virology, Heidelberg University Hospital, Heidelberg, Germany

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http://dx.doi.org/10.1128/JVI.00504-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944280PMC
August 2016

Hydrophilic trans-Cyclooctenylated Noncanonical Amino Acids for Fast Intracellular Protein Labeling.

Chembiochem 2016 08 7;17(16):1518-24. Epub 2016 Jul 7.

Hungarian Academy of Sciences, Research Centre for Natural Sciences, Institute of Organic Chemistry, Magyar tudósok krt. 2, 1117, Budapest, Hungary.

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http://dx.doi.org/10.1002/cbic.201600284DOI Listing
August 2016

Experimental systems for studying Plasmodium/HIV coinfection.

FEBS Lett 2016 07 15;590(13):2000-13. Epub 2016 Apr 15.

Center for Infectious Diseases, Integrative Virology, University Hospital Heidelberg, Germany.

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http://dx.doi.org/10.1002/1873-3468.12151DOI Listing
July 2016

Integrative analysis of pathogen replication and spread: zooming into increasing complexity.

FEBS Lett 2016 07;590(13):1855-7

Department of Infectious Diseases, Virology, University Hospital Heidelberg, Germany.

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http://dx.doi.org/10.1002/1873-3468.12253DOI Listing
July 2016

Cell Surface Downregulation of NK Cell Ligands by Patient-Derived HIV-1 Vpu and Nef Alleles.

J Acquir Immune Defic Syndr 2016 May;72(1):1-10

*Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, Heidelberg, Germany; †German Center for Infection Research, Heidelberg University, Heidelberg, Germany; ‡Department of Clinical Immunology and Rheumatology, Hannover Medical School, Hannover, Germany; and §German Center for Infection Research, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1097/QAI.0000000000000917DOI Listing
May 2016

Reinforcing the LINC complex connection to actin filaments: the role of FHOD1 in TAN line formation and nuclear movement.

Cell Cycle 2015 17;14(14):2200-5. Epub 2015 Jun 17.

a Department of Pathology & Cell Biology ; Columbia University ; New York , NY USA.

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http://dx.doi.org/10.1080/15384101.2015.1053665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614392PMC
April 2016

HIV-Nef and ADAM17-Containing Plasma Extracellular Vesicles Induce and Correlate with Immune Pathogenesis in Chronic HIV Infection.

EBioMedicine 2016 Apr 3;6:103-113. Epub 2016 Mar 3.

Department of Dermatology, University Hospital Erlangen, Friedrich-Alexander-University of Erlangen-Nürnberg, Translational Research Center, Ulmenweg 12, 91054 Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856776PMC
April 2016

Modest attenuation of HIV-1 Vpu alleles derived from elite controller plasma.

PLoS One 2015 20;10(3):e0120434. Epub 2015 Mar 20.

Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, INF 324, Heidelberg, Germany; German Center for Infection Research, Heidelberg University, Heidelberg. Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120434PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368696PMC
February 2016

Sensing of HIV-1 Infection in Tzm-bl Cells with Reconstituted Expression of STING.

J Virol 2016 02 9;90(4):2064-76. Epub 2015 Dec 9.

Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, Heidelberg, Germany German Center for Infection Research, Heidelberg University, Heidelberg. Germany

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http://jvi.asm.org/lookup/doi/10.1128/JVI.02966-15
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http://dx.doi.org/10.1128/JVI.02966-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733976PMC
February 2016

Spotlight on HIV-1 Nef: SERINC3 and SERINC5 Identified as Restriction Factors Antagonized by the Pathogenesis Factor.

Authors:
Oliver T Fackler

Viruses 2015 Dec 19;7(12):6730-8. Epub 2015 Dec 19.

Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.

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http://www.mdpi.com/1999-4915/7/12/2970
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http://dx.doi.org/10.3390/v7122970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690893PMC
December 2015

Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex.

mBio 2015 Sep 8;6(5):e01309-15. Epub 2015 Sep 8.

Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, Heidelberg, Germany

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http://dx.doi.org/10.1128/mBio.01309-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600113PMC
September 2015

Formin-like 2 Promotes β1-Integrin Trafficking and Invasive Motility Downstream of PKCα.

Dev Cell 2015 Aug 6;34(4):475-83. Epub 2015 Aug 6.

Institute of Pharmacology, University of Marburg, 35043 Marburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2015.06.015DOI Listing
August 2015

SAMHD1's protein expression profile in humans.

J Leukoc Biol 2015 Jul 2;98(1):5-14. Epub 2015 Feb 2.

*Institute of Medical Virology, National Reference Center for Retroviruses, University of Frankfurt, Germany; Department of Infectious Diseases, Integrative Virology, Institute of Pathology, and Department of Otolaryngology, Head and Neck Surgery, University of Heidelberg, Germany; German Centre for Infection Research, Heidelberg, Germany; and Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, Ghent, Belgium

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http://dx.doi.org/10.1189/jlb.4HI0714-338RRDOI Listing
July 2015

HIV-1 reprograms the migration of macrophages.

Blood 2015 Mar 19;125(10):1611-22. Epub 2014 Dec 19.

Centre National de la Recherche Scientifique Unité Mixte de Recherche 5089, Institut de Pharmacologie et de Biologie Structurale, Toulouse Cedex 04, France; Université de Toulouse-Paul Sabatier, Institut de Pharmacologie et de Biologie Structurale, Toulouse, France;

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http://dx.doi.org/10.1182/blood-2014-08-596775DOI Listing
March 2015

HIV-1 Nef and Vpu are functionally redundant broad-spectrum modulators of cell surface receptors, including tetraspanins.

J Virol 2014 Dec 1;88(24):14241-57. Epub 2014 Oct 1.

Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, Heidelberg, Germany

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http://dx.doi.org/10.1128/JVI.02333-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249113PMC
December 2014

Adding new dimensions: towards an integrative understanding of HIV-1 spread.

Nat Rev Microbiol 2014 Aug;12(8):563-74

1] The Center for Immunology and Inflammatory Diseases (CIID), Massachusetts General Hospital, Boston, Massachusetts 02114, USA. [2] Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nrmicro3309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687059PMC
August 2014

FHOD1 interaction with nesprin-2G mediates TAN line formation and nuclear movement.

Nat Cell Biol 2014 Jul 1;16(7):708-15. Epub 2014 Jun 1.

Department of Pathology and Cell Biology, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1038/ncb2981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113092PMC
July 2014

Heterologous Src homology 4 domains support membrane anchoring and biological activity of HIV-1 Nef.

J Biol Chem 2014 May 4;289(20):14030-44. Epub 2014 Apr 4.

From the Department of Infectious Diseases, Integrative Virology and

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http://dx.doi.org/10.1074/jbc.M114.563528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022873PMC
May 2014

MxB/Mx2: the latest piece in HIV's interferon puzzle.

EMBO Rep 2013 Dec 1;14(12):1028-9. Epub 2013 Nov 1.

Department of Infectious Diseases, University Hospital Heidelberg, Germany.

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http://dx.doi.org/10.1038/embor.2013.172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981093PMC
December 2013

HIV-1 Nef disrupts membrane-microdomain-associated anterograde transport for plasma membrane delivery of selected Src family kinases.

Cell Microbiol 2013 Oct 3;15(10):1605-21. Epub 2013 May 3.

Department of Infectious Diseases, Virology, University Hospital Heidelberg, INF 324, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1111/cmi.12148DOI Listing
October 2013

Restrictions to HIV-1 replication in resting CD4+ T lymphocytes.

Cell Res 2013 Jul 4;23(7):876-85. Epub 2013 Jun 4.

Department of Infectious Diseases, Virology, University Hospital Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1038/cr.2013.74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698640PMC
July 2013

FHOD1 is a combined actin filament capping and bundling factor that selectively associates with actin arcs and stress fibers.

J Cell Sci 2013 Apr 26;126(Pt 8):1891-901. Epub 2013 Feb 26.

Department of Physical Biochemistry, Max Planck Institute of Molecular Physiology, 44227 Dortmund, Germany.

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http://dx.doi.org/10.1242/jcs.126706DOI Listing
April 2013

HIV-1 Nef: a multifaceted modulator of T cell receptor signaling.

Cell Commun Signal 2012 Dec 10;10(1):39. Epub 2012 Dec 10.

Department of Infectious Diseases, Virology, University Hospital Heidelberg, INF 324, Heidelberg, 69120, Germany.

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http://dx.doi.org/10.1186/1478-811X-10-39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534016PMC
December 2012

HIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo.

Proc Natl Acad Sci U S A 2012 Nov 23;109(45):18541-6. Epub 2012 Oct 23.

Department of Infectious Diseases-Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1204322109
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http://dx.doi.org/10.1073/pnas.1204322109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494961PMC
November 2012

HIV-1 Nef limits communication between linker of activated T cells and SLP-76 to reduce formation of SLP-76-signaling microclusters following TCR stimulation.

J Immunol 2012 Aug 16;189(4):1898-910. Epub 2012 Jul 16.

Department of Infectious Diseases, Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.4049/jimmunol.1200652DOI Listing
August 2012

Differing and isoform-specific roles for the formin DIAPH3 in plasma membrane blebbing and filopodia formation.

Cell Res 2012 Apr 20;22(4):728-45. Epub 2011 Dec 20.

Department of Infectious Diseases, Virology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1038/cr.2011.202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317560PMC
April 2012

HIV-1 Vpu's lipid raft association is dispensable for counteraction of the particle release restriction imposed by CD317/Tetherin.

Virology 2012 Mar 4;424(1):33-44. Epub 2012 Jan 4.

Department of Infectious Diseases, Virology, University of Heidelberg, INF 324, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.virol.2011.12.008DOI Listing
March 2012

HIV-1 Nef compensates for disorganization of the immunological synapse by inducing trans-Golgi network-associated Lck signaling.

Blood 2012 Jan 28;119(3):786-97. Epub 2011 Nov 28.

Department of Infectious Diseases, Virology, University Hospital Heidelberg, Germany.

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http://dx.doi.org/10.1182/blood-2011-08-373209DOI Listing
January 2012

Nef does not inhibit F-actin remodelling and HIV-1 cell-cell transmission at the T lymphocyte virological synapse.

Eur J Cell Biol 2011 Nov 1;90(11):913-21. Epub 2010 Nov 1.

Department of Infectious Diseases, Virology, University Hospital Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ejcb.2010.09.010DOI Listing
November 2011

How HIV takes advantage of the cytoskeleton in entry and replication.

Viruses 2011 04 28;3(4):293-311. Epub 2011 Mar 28.

Department of Infectious Diseases, Virology, University Hospital Heidelberg, Heidelberg, Germany.

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http://www.mdpi.com/1999-4915/3/4/293
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http://dx.doi.org/10.3390/v3040293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185699PMC
April 2011

Inhibition of the Nef regulatory protein of HIV-1 by a single-domain antibody.

Blood 2011 Mar 3;117(13):3559-68. Epub 2011 Feb 3.

Institut Cochin, CNRS UMR8104, Université Paris Descartes, 27 Rue du Faubourg Saint-Jacques,Paris, France.

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http://dx.doi.org/10.1182/blood-2010-07-296749DOI Listing
March 2011

β-TrCP is dispensable for Vpu's ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release.

Retrovirology 2011 Feb 10;8. Epub 2011 Feb 10.

Department of Infectious Diseases, Virology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1186/1742-4690-8-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049139PMC
February 2011

Role of the C-terminal domain of the HIV-1 glycoprotein in cell-to-cell viral transmission between T lymphocytes.

Retrovirology 2010 May 12;7:43. Epub 2010 May 12.

Forschungsschwerpunkt Infektion und Krebs, F020, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1186/1742-4690-7-43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875203PMC
May 2010

Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.

J Virol 2010 Apr 10;84(8):3935-48. Epub 2010 Feb 10.

Department of Infectious Diseases, Virology, University of Heidelberg, INF 324, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1128/JVI.02467-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849517PMC
April 2010

HIV-1 Nef interferes with host cell motility by deregulation of Cofilin.

Cell Host Microbe 2009 Aug;6(2):174-86

Department of Virology, Im Neuenheimer Feld 324, University of Heidelberg, Heidelberg 69120, Germany.

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http://dx.doi.org/10.1016/j.chom.2009.06.004DOI Listing
August 2009

HIV-1 Nef perturbs artificial membranes: investigation of the contribution of the myristoyl anchor.

Biophys J 2009 Apr;96(8):3242-50

Institute of Organic and Biomolecular Chemistry, Georg-August University, 37077 Göttingen, Germany.

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http://dx.doi.org/10.1016/j.bpj.2008.12.3947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718304PMC
April 2009

Induction of HIV transcription by Nef involves Lck activation and protein kinase C theta raft recruitment leading to activation of ERK1/2 but not NF kappa B.

J Immunol 2008 Dec;181(12):8425-32

Otto-von-Guericke University of Magdeburg, Institute of Molecular and Clinical Immunology, Magdeburg, Germany.

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http://dx.doi.org/10.4049/jimmunol.181.12.8425DOI Listing
December 2008

The Diaphanous-related Formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbing.

J Biol Chem 2008 Oct 11;283(41):27891-903. Epub 2008 Aug 11.

Department of Virology, University of Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1074/jbc.M801800200DOI Listing
October 2008

HIV-1 at the immunological and T-lymphocytic virological synapse.

Biol Chem 2008 Oct;389(10):1253-60

Department of Virology, University of Heidelberg, INF 324, D-69120 Heidelberg, Germany.

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https://www.degruyter.com/view/j/bchm.2008.389.issue-10/bc.2
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http://dx.doi.org/10.1515/BC.2008.143DOI Listing
October 2008

The human formin FHOD1 contains a bipartite structure of FH3 and GTPase-binding domains required for activation.

Structure 2008 Sep;16(9):1313-23

Abteilung Physikalische Biochemie, Max-Planck-Institut für Molekulare Physiologie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S096921260800257
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http://dx.doi.org/10.1016/j.str.2008.06.008DOI Listing
September 2008

Cell motility through plasma membrane blebbing.

J Cell Biol 2008 Jun 9;181(6):879-84. Epub 2008 Jun 9.

Department of Virology, University of Heidelberg, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1083/jcb.200802081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426937PMC
June 2008

Novel (n)PKC kinases phosphorylate Nef for increased HIV transcription, replication and perinuclear targeting.

Virology 2008 Jan 29;370(1):45-54. Epub 2007 Sep 29.

University of Miami, Miller School of Medicine, Department of Microbiology and Immunology, BCRI 739, Miami, FL 33136, USA.

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http://dx.doi.org/10.1016/j.virol.2007.08.015DOI Listing
January 2008

SH4-domain-induced plasma membrane dynamization promotes bleb-associated cell motility.

J Cell Sci 2007 Nov;120(Pt 21):3820-9

Heidelberg University Biochemistry Center, Im Neuenheimer Feld 328, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1242/jcs.011130DOI Listing
November 2007

Modulation of the immunological synapse: a key to HIV-1 pathogenesis?

Nat Rev Immunol 2007 Apr;7(4):310-7

Oliver T. Fackler is at the Department of Virology, University of Heidelberg, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1038/nri2041DOI Listing
April 2007

Specific and distinct determinants mediate membrane binding and lipid raft incorporation of HIV-1(SF2) Nef.

Virology 2006 Nov 17;355(2):175-91. Epub 2006 Aug 17.

Department of Virology, University of Heidelberg, 69120 Heidelberg, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S004268220600443
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http://dx.doi.org/10.1016/j.virol.2006.07.003DOI Listing
November 2006

Functional characterization of HIV-1 Nef mutants in the context of viral infection.

Virology 2006 Aug 8;351(2):322-39. Epub 2006 May 8.

Department of Virology, University of Heidelberg, INF 324, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.virol.2006.03.044DOI Listing
August 2006

Interactions of human retroviruses with the host cell cytoskeleton.

Curr Opin Microbiol 2006 Aug 3;9(4):409-15. Epub 2006 Jul 3.

Department of Virology, University of Heidelberg, Im Neuenheimer Feld 324, D-69120 Heidelberg, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S136952740600093
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http://dx.doi.org/10.1016/j.mib.2006.06.010DOI Listing
August 2006

The HIV-1 pathogenicity factor Nef interferes with maturation of stimulatory T-lymphocyte contacts by modulation of N-Wasp activity.

J Biol Chem 2006 Jul 10;281(28):19618-30. Epub 2006 May 10.

Department of Virology, University of Heidelberg, Im Neuenheimer Feld 324, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1074/jbc.M513802200DOI Listing
July 2006

Modulation of specific surface receptors and activation sensitization in primary resting CD4+ T lymphocytes by the Nef protein of HIV-1.

J Leukoc Biol 2006 Mar 19;79(3):616-27. Epub 2005 Dec 19.

Department of Virology, University of Heidelberg, Im Neuenheimer Feld 324, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1189/jlb.0805461DOI Listing
March 2006

Biochemical characterization of the diaphanous autoregulatory interaction in the formin homology protein FHOD1.

J Biol Chem 2006 Feb 16;281(8):5084-93. Epub 2005 Dec 16.

Max Planck Institute for Molecular Physiology, Department of Physical Biochemistry, D-44227 Dortmund, Germany.

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http://dx.doi.org/10.1074/jbc.M509226200DOI Listing
February 2006

FHOD1 coordinates actin filament and microtubule alignment to mediate cell elongation.

Exp Cell Res 2005 May;306(1):192-202

Abteilung Virologie, Universitätsklinikum Heidelberg, INF 324, D-69120 Heidelberg, Germany.

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May 2005