Oliver Peter

The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour.

Authors:

Enrico Castroflorio Joery den Hoed Daria Svistunova Mattéa J Finelli Alberto Cebrian-Serrano Silvia Corrochano Andrew R Bassett Benjamin Davies Peter L Oliver

Cell Mol Life Sci 2020 Dec 19. Epub 2020 Dec 19.

MRC Harwell Institute, Harwell Campus, Oxfordshire, OX11 0RD, UK.

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December 2020

ROS Generation in Microglia: Understanding Oxidative Stress and Inflammation in Neurodegenerative Disease.

Authors:

Dominic S A Simpson Peter L Oliver

Antioxidants (Basel) 2020 Aug 13;9(8). Epub 2020 Aug 13.

Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire OX11 0RD, UK.

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August 2020

Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior.

Authors:

Benjamin H M Hunn Siv Vingill Sarah Threlfell Javier Alegre-Abarrategui Morgane Magdelyns Thierry Deltheil Nora Bengoa-Vergniory Peter L Oliver Milena Cioroch Natalie M Doig David M Bannerman Stephanie J Cragg Richard Wade-Martins

Cell Rep 2019 10;29(4):920-931.e7

Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK. Electronic address:

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October 2019

Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo.

Authors:

Matthew G Williamson Mattéa J Finelli James N Sleigh Amy Reddington David Gordon Kevin Talbot Kay E Davies Peter L Oliver

Hum Mol Genet 2019 11;28(21):3584-3599

Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford OX1 3PT, UK.

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November 2019

Limitations to adaptive homeostasis in an hyperoxia-induced model of accelerated ageing.

Authors:

Laura C D Pomatto Patrick Y Sun Kelsi Yu Sandhyarani Gullapalli Conscience P Bwiza Christina Sisliyan Sarah Wong Hongqiao Zhang Henry Jay Forman Peter L Oliver Kay E Davies Kelvin J A Davies

Redox Biol 2019 06 14;24:101194. Epub 2019 Apr 14.

Leonard Davis School of Gerontology of the Ethel Percy Andrus Gerontology Center, University of Southern California, Los Angeles, CA 90089-0191, USA; Division of Molecular & Computational Biology, Department of Biological Sciences of the Dornsife College of Letters, Arts, and Sciences, University of Southern California, Los Angeles, CA 90089-0191, USA; Department of Biochemistry & Molecular Medicine, Keck School of Medicine of USC, University of Southern California, University of Southern California, Los Angeles, CA 90089-0191, USA. Electronic address:

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June 2019

Loss of disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities.

Authors:

Michelle Stewart Petrina Lau Gareth Banks Rasneer Sonia Bains Enrico Castroflorio Peter L Oliver Christine L Dixon Michael C Kruer Dimitri M Kullmann Abraham Acevedo-Arozena Sara E Wells Silvia Corrochano Patrick M Nolan

Dis Model Mech 2019 02 22;12(2). Epub 2019 Feb 22.

MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK

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February 2019

Novel high-throughput myofibroblast assays identify agonists with therapeutic potential in pulmonary fibrosis that act via EP2 and EP4 receptors.

Authors:

Patrick Sieber Anny Schäfer Raphael Lieberherr François Le Goff Manuel Stritt Richard W D Welford John Gatfield Oliver Peter Oliver Nayler Urs Lüthi

PLoS One 2018 28;13(11):e0207872. Epub 2018 Nov 28.

Idorsia Pharmaceuticals Ltd., Allschwil, Switzerland.

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April 2019

Oxidation resistance 1 regulates post-translational modifications of peroxiredoxin 2 in the cerebellum.

Authors:

Daria M Svistunova Jillian N Simon Elzbieta Rembeza Mark Crabtree Wyatt W Yue Peter L Oliver Mattéa J Finelli

Free Radic Biol Med 2019 01 31;130:151-162. Epub 2018 Oct 31.

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK. Electronic address:

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January 2019

The epilepsy-associated protein TBC1D24 is required for normal development, survival and vesicle trafficking in mammalian neurons.

Authors:

Mattéa J Finelli Davide Aprile Enrico Castroflorio Alexander Jeans Matteo Moschetta Lauren Chessum Matteo T Degiacomi Julia Grasegger Alexis Lupien-Meilleur Andrew Bassett Elsa Rossignol Philippe M Campeau Michael R Bowl Fabio Benfenati Anna Fassio Peter L Oliver

Hum Mol Genet 2019 02;28(4):584-597

Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford, UK.

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February 2019

Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction.

Authors:

David Gordon Ruxandra Dafinca Jakub Scaber Javier Alegre-Abarrategui Lucy Farrimond Connor Scott Daniel Biggs Louisa Kent Peter L Oliver Benjamin Davies Olaf Ansorge Richard Wade-Martins Kevin Talbot

Neurobiol Dis 2019 01 2;121:148-162. Epub 2018 Oct 2.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. Electronic address:

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January 2019

Absent sleep EEG spindle activity in GluA1 (Gria1) knockout mice: relevance to neuropsychiatric disorders.

Authors:

Gauri Ang Laura E McKillop Ross Purple Cristina Blanco-Duque Stuart N Peirson Russell G Foster Paul J Harrison Rolf Sprengel Kay E Davies Peter L Oliver David M Bannerman Vladyslav V Vyazovskiy

Transl Psychiatry 2018 08 14;8(1):154. Epub 2018 Aug 14.

Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford, OX1 3PT, UK.

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August 2018

Oxidation Resistance 1 Modulates Glycolytic Pathways in the Cerebellum via an Interaction with Glucose-6-Phosphate Isomerase.

Authors:

Mattéa J Finelli Teresa Paramo Elisabete Pires Brent J Ryan Richard Wade-Martins Philip C Biggin James McCullagh Peter L Oliver

Mol Neurobiol 2019 Mar 15;56(3):1558-1577. Epub 2018 Jun 15.

Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford, OX1 3PT, UK.

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March 2019

Targeted deletion of the Ncoa7 gene results in incomplete distal renal tubular acidosis in mice.

Authors:

Maria Merkulova Teodor G Păunescu Anil V Nair Chia-Yu Wang Diane E Capen Peter L Oliver Sylvie Breton Dennis Brown

Am J Physiol Renal Physiol 2018 07 31;315(1):F173-F185. Epub 2018 Jan 31.

Center for Systems Biology, Program in Membrane Biology and Division of Nephrology, Massachusetts General Hospital and Harvard Medical School , Boston, Massachusetts.

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July 2018