Oliver Kurzai

Oliver Kurzai

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Oliver Kurzai

Oliver Kurzai

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ECMM CandiReg-A ready to use platform for outbreaks and epidemiological studies.

Authors:
Philipp Koehler Maiken Cavling Arendrup Sevtap Arikan-Akdagli Matteo Bassetti Stéphane Bretagne Lena Klingspor Katrien Lagrou Jacques F Meis Riina Rautemaa-Richardson Silke Schelenz Axel Hamprecht Felix C Koehler Oliver Kurzai Jon Salmanton-García Jörg-Janne Vehreschild Alexandre Alanio Ana Alastruey-Izquierdo Valentina Arsic Arsenijevic Jean-Pierre Gangneux Neil A R Gow Suzana Hadina Petr Hamal Elizabeth Johnson Nikolay Klimko Cornelia Lass-Flörl Mihai Mares Volkan Özenci Tamas Papp Emmanuel Roilides Raquel Sabino Esther Segal Alida Fe Talento Anna Maria Tortorano Paul E Verweij Martin Hoenigl Oliver A Cornely

Mycoses 2019 Oct 1;62(10):920-927. Epub 2019 Aug 1.

Faculty of Medicine, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf (CIO ABCD), Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1111/myc.12963DOI Listing
October 2019

Multiple Signaling Pathways Involved in Human Dendritic Cell Maturation Are Affected by the Fungal Quorum-Sensing Molecule Farnesol.

Authors:
Wolfgang Vivas Ines Leonhardt Kerstin Hünniger Antje Häder Alessandra Marolda Oliver Kurzai

J Immunol 2019 Oct 16. Epub 2019 Oct 16.

Fungal Septomics, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, 07745 Jena, Germany;

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http://dx.doi.org/10.4049/jimmunol.1900431DOI Listing
October 2019

Candida auris in Germany and Previous Exposure to Foreign Healthcare.

Authors:
Axel Hamprecht Amelia E Barber Sibylle C Mellinghoff Philipp Thelen Grit Walther Yanying Yu Priya Neurgaonkar Thomas Dandekar Oliver A Cornely Ronny Martin Oliver Kurzai

Emerg Infect Dis 2019 09 17;25(9):1763-1765. Epub 2019 Sep 17.

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http://dx.doi.org/10.3201/eid2509.190262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711216PMC
September 2019

(Ascomycota: Ophiostomatales) - A soil-borne fungus with pathogenic potential in the eastern quoll ().

Authors:
Anne Nesseler Nicole Schauerte Christina Geiger Kerstin Kaerger Grit Walther Oliver Kurzai Tobias Eisenberg

Med Mycol Case Rep 2019 Sep 30;25:39-44. Epub 2019 Jul 30.

Hessian State Laboratory (LHL), Department of Veterinary Medicine, Schubertstr. 60, 35392, Giessen, Germany.

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http://dx.doi.org/10.1016/j.mmcr.2019.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695275PMC
September 2019

First Insights in NK-DC Cross-Talk and the Importance of Soluble Factors During Infection With .

Authors:
Esther Weiss Sabrina Ziegler Mirjam Fliesser Anna-Lena Schmitt Kerstin Hünniger Oliver Kurzai Charles-Oliver Morton Hermann Einsele Juergen Loeffler

Front Cell Infect Microbiol 2018 20;8:288. Epub 2018 Aug 20.

Department of Internal Medicine II, University Hospital Wuerzburg, WÜ4i, Wuerzburg, Germany.

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http://dx.doi.org/10.3389/fcimb.2018.00288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110135PMC
August 2019

A Revised Species Concept for Opportunistic Species Reveals Species-Specific Antifungal Susceptibility Profiles.

Authors:
Lysett Wagner Sybren de Hoog Ana Alastruey-Izquierdo Kerstin Voigt Oliver Kurzai Grit Walther

Antimicrob Agents Chemother 2019 Aug 25;63(8). Epub 2019 Jul 25.

German National Reference Center for Invasive Fungal Infections, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, Jena, Germany

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http://aac.asm.org/lookup/doi/10.1128/AAC.00653-19
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http://dx.doi.org/10.1128/AAC.00653-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658771PMC
August 2019

Quantitative Simulations Predict Treatment Strategies Against Fungal Infections in Virtual Neutropenic Patients.

Authors:
Sandra Timme Teresa Lehnert Maria T E Prauße Kerstin Hünniger Ines Leonhardt Oliver Kurzai Marc Thilo Figge

Front Immunol 2018 4;9:667. Epub 2018 Apr 4.

Research Group Applied Systems Biology, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, Jena, Germany.

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http://dx.doi.org/10.3389/fimmu.2018.00667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893870PMC
June 2019

Phagocytes as central players in the defence against invasive fungal infection.

Authors:
Kerstin Hünniger Oliver Kurzai

Semin Cell Dev Biol 2019 May 7;89:3-15. Epub 2018 Apr 7.

Institute for Hygiene and Microbiology, University of Würzburg, Germany; Septomics Research Center, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knoell-Institute, Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2018.03.021DOI Listing
May 2019

Predictive Virtual Infection Modeling of Fungal Immune Evasion in Human Whole Blood.

Authors:
Maria T E Prauße Teresa Lehnert Sandra Timme Kerstin Hünniger Ines Leonhardt Oliver Kurzai Marc Thilo Figge

Front Immunol 2018 21;9:560. Epub 2018 Mar 21.

Applied Systems Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), Jena, Germany.

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http://dx.doi.org/10.3389/fimmu.2018.00560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871695PMC
May 2019

Invasive Fungal Infection.

Authors:
Marie von Lilienfeld-Toal Johannes Wagener Hermann Einsele Oliver A Cornely Oliver Kurzai

Dtsch Arztebl Int 2019 04;116(16):271-278

National Reference Center for Invasive Fungal Infections, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute (HKI), Jena; Clinic of Internal Medicine II, University Hospital Jena; Institute for Hygiene and Microbiology, University of Würzburg, Chair of Medical Microbiology and Mycology, Würzburg; Department of Internal Medicine II, University Hospital of Würzburg; InfectControl 2020, Jena/Würzburg; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Department I of Internal Medicine, at the University Hospital of Cologne, European Excellence Center for Medical Mycology (ECMM), DGerman Center for Infection Research(DZIF) Partner Site Bonn Köln, Cologne University.

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http://dx.doi.org/10.3238/arztebl.2019.0271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549129PMC
April 2019

Automated tracking of label-free cells with enhanced recognition of whole tracks.

Authors:
Naim Al-Zaben Anna Medyukhina Stefanie Dietrich Alessandra Marolda Kerstin Hünniger Oliver Kurzai Marc Thilo Figge

Sci Rep 2019 Mar 1;9(1):3317. Epub 2019 Mar 1.

Applied Systems Biology, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute (HKI), Jena, Germany.

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http://dx.doi.org/10.1038/s41598-019-39725-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397148PMC
March 2019

Comparative Genomics of Serial Isolates and the Rapid Acquisition of Echinocandin Resistance during Therapy.

Authors:
Amelia E Barber Michael Weber Kerstin Kaerger Jörg Linde Hanna Gölz Daniel Duerschmied Antonie Markert Reinhard Guthke Grit Walther Oliver Kurzai

Antimicrob Agents Chemother 2019 02 29;63(2). Epub 2019 Jan 29.

National Reference Center for Invasive Mycoses, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute, Jena, Germany

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http://aac.asm.org/lookup/doi/10.1128/AAC.01628-18
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http://dx.doi.org/10.1128/AAC.01628-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355595PMC
February 2019

Validation of a simplified in vitro Transwell model of the alveolar surface to assess host immunity induced by different morphotypes of Aspergillus fumigatus.

Authors:
C Oliver Morton Sebastian Wurster Mirjam Fliesser Frank Ebel Lukas Page Kerstin Hünniger Oliver Kurzai Anna Lena Schmitt Denise Michel Jan Springer Hermann Einsele Juergen Loeffler

Int J Med Microbiol 2018 Dec 3;308(8):1009-1017. Epub 2018 Sep 3.

Medical Hospital II, University Hospital Wuerzburg, 97080 Wuerzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijmm.2018.09.001DOI Listing
December 2018

Diagnosis of invasive fungal diseases in haematology and oncology: 2018 update of the recommendations of the infectious diseases working party of the German society for hematology and medical oncology (AGIHO).

Authors:
Markus Ruhnke Gerhard Behre Dieter Buchheidt Maximilian Christopeit Axel Hamprecht Werner Heinz Claus-Peter Heussel Marius Horger Oliver Kurzai Meinolf Karthaus Jürgen Löffler Georg Maschmeyer Olaf Penack Christina Rieger Volker Rickerts Jörg Ritter Martin Schmidt-Hieber Nikolai Schuelper Stefan Schwartz Andrew Ullmann Jörg Janne Vehreschild Marie von Lilienfeld-Toal Thomas Weber Hans H Wolf

Mycoses 2018 Nov 3;61(11):796-813. Epub 2018 Sep 3.

Department of Internal Medicine IV, Universitätsklinik Halle, Halle, Germany.

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http://dx.doi.org/10.1111/myc.12838DOI Listing
November 2018

Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus .

Authors:
Vera Voltersen Matthew G Blango Sahra Herrmann Franziska Schmidt Thorsten Heinekamp Maria Strassburger Thomas Krüger Petra Bacher Jasmin Lother Esther Weiss Kerstin Hünniger Hong Liu Peter Hortschansky Alexander Scheffold Jürgen Löffler Sven Krappmann Sandor Nietzsche Oliver Kurzai Hermann Einsele Olaf Kniemeyer Scott G Filler Utz Reichard Axel A Brakhage

MBio 2018 10 2;9(5). Epub 2018 Oct 2.

Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany

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http://mbio.asm.org/lookup/doi/10.1128/mBio.01557-18
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http://dx.doi.org/10.1128/mBio.01557-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168859PMC
October 2018

(1,3)-β-D-glucan-based diagnosis of invasive Candida infection versus culture-based diagnosis in patients with sepsis and with an increased risk of invasive Candida infection (CandiSep): study protocol for a randomized controlled trial.

Authors:
Frank Bloos Jürgen Held Peter Schlattmann Nicole Brillinger Oliver Kurzai Oliver A Cornely Daniel Thomas-Rüddel

Trials 2018 Sep 4;19(1):472. Epub 2018 Sep 4.

Center for Sepsis Control & Care, Jena University Hospital, Jena, Germany.

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https://trialsjournal.biomedcentral.com/articles/10.1186/s13
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http://dx.doi.org/10.1186/s13063-018-2868-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124015PMC
September 2018

Azole-induced cell wall carbohydrate patches kill Aspergillus fumigatus.

Authors:
Bernadette Geißel Veronika Loiko Isabel Klugherz Zhaojun Zhu Nikola Wagener Oliver Kurzai Cees A M J J van den Hondel Johannes Wagener

Nat Commun 2018 08 6;9(1):3098. Epub 2018 Aug 6.

Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Medizinische Fakultät, LMU München, Pettenkoferstraße 9a, 80336, Munich, Germany.

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http://dx.doi.org/10.1038/s41467-018-05497-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078979PMC
August 2018

Tracheal, laryngeal and pulmonary mucormycosis followed by organizing pneumonia in a patient with Adult Onset Still's Disease.

Authors:
Fabian Leo Michael Zeh Annegret Prothmann Oliver Kurzai Sylke Kurz Christian Grohé

Med Mycol Case Rep 2018 Jun 6;20:28-32. Epub 2018 Feb 6.

Department of Respiratory Medicine, Evangelische Lungenklinik Berlin, Lindenberger Weg 27, 13125 Berlin, Germany.

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http://dx.doi.org/10.1016/j.mmcr.2018.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105918PMC
June 2018

Farnesol signalling in Candida albicans - more than just communication.

Authors:
Melanie Polke Ines Leonhardt Oliver Kurzai Ilse D Jacobsen

Crit Rev Microbiol 2018 Mar 13;44(2):230-243. Epub 2017 Jun 13.

a Research Group Microbial Immunology , Leibniz Institute for Natural Product Research and Infection Biology, Hans Knoell Institute (HKI) , Jena , Germany.

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http://dx.doi.org/10.1080/1040841X.2017.1337711DOI Listing
March 2018

FunResDB-A web resource for genotypic susceptibility testing of Aspergillus fumigatus.

Authors:
Michael Weber Jonas Schaer Grit Walther Kerstin Kaerger Jörg Steinmann Peter-Michael Rath Birgit Spiess Dieter Buchheidt Axel Hamprecht Oliver Kurzai

Med Mycol 2018 Jan;56(1):117-120

German National Reference Center for Invasive Fungal Infections - NRZMyk, Septomics Research Centre, Leibniz-Institute for Natural Product Research and Infection Biology - Hans-Knoell-Institute, 07745 Jena, Germany.

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http://dx.doi.org/10.1093/mmy/myx015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896429PMC
January 2018

CO sensing in fungi: at the heart of metabolic signaling.

Authors:
Ronny Martin Susann Pohlers Fritz A Mühlschlegel Oliver Kurzai

Curr Genet 2017 Dec 10;63(6):965-972. Epub 2017 May 10.

Institute for Hygiene and Microbiology, Julius-Maximilians-University Würzburg, 97080, Würzburg, Germany.

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http://link.springer.com/10.1007/s00294-017-0700-0
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http://dx.doi.org/10.1007/s00294-017-0700-0DOI Listing
December 2017

Fusarium Keratitis in Germany.

Authors:
Grit Walther Serena Stasch Kerstin Kaerger Axel Hamprecht Mathias Roth Oliver A Cornely Gerd Geerling Colin R Mackenzie Oliver Kurzai Marie von Lilienfeld-Toal

J Clin Microbiol 2017 10 26;55(10):2983-2995. Epub 2017 Jul 26.

National Reference Center for Invasive Fungal Infections (NRZMyk), Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany.

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http://dx.doi.org/10.1128/JCM.00649-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625384PMC
October 2017

IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity.

Authors:
Cristina Cunha Samuel M Gonçalves Cláudio Duarte-Oliveira Luís Leite Katrien Lagrou António Marques Carmen B Lupiañez Inês Mesquita Joana Gaifem Ana Margarida Barbosa Carlos Pinho Vaz Rosa Branca Fernando Campilho Fátima Freitas Dário Ligeiro Cornelia Lass-Flörl Jürgen Löffler Manuel Jurado Margarida Saraiva Oliver Kurzai Fernando Rodrigues António G Castro Ricardo Silvestre Juan Sainz Johan A Maertens Egídio Torrado Ilse D Jacobsen João F Lacerda António Campos Agostinho Carvalho

J Allergy Clin Immunol 2017 09 4;140(3):867-870.e9. Epub 2017 Apr 4.

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal; ICVS/3B's PT Government Associate Laboratory, Braga/Guimarães, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.02.034DOI Listing
September 2017

Persistence within dendritic cells marks an antifungal evasion and dissemination strategy of Aspergillus terreus.

Authors:
Shih-Hung Hsieh Oliver Kurzai Matthias Brock

Sci Rep 2017 09 6;7(1):10590. Epub 2017 Sep 6.

Fungal Genetics and Biology Group, School of Life Sciences, University of Nottingham, University Park, NG7 2RD, Nottingham, UK.

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http://dx.doi.org/10.1038/s41598-017-10914-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587622PMC
September 2017

CD56 Is a Pathogen Recognition Receptor on Human Natural Killer Cells.

Authors:
Sabrina Ziegler Esther Weiss Anna-Lena Schmitt Jan Schlegel Anne Burgert Ulrich Terpitz Markus Sauer Lorenzo Moretta Simona Sivori Ines Leonhardt Oliver Kurzai Hermann Einsele Juergen Loeffler

Sci Rep 2017 07 21;7(1):6138. Epub 2017 Jul 21.

Department of Internal Medicine II, WÜ4i, University Hospital Wuerzburg, Wuerzburg, Germany.

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http://dx.doi.org/10.1038/s41598-017-06238-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522490PMC
July 2017

C-Terminal Alpha-1 Antitrypsin Peptide: A New Sepsis Biomarker with Immunomodulatory Function.

Authors:
Nancy Blaurock Diana Schmerler Kerstin Hünniger Oliver Kurzai Katrin Ludewig Michael Baier Frank Martin Brunkhorst Diana Imhof Michael Kiehntopf

Mediators Inflamm 2016 13;2016:6129437. Epub 2016 Jun 13.

Department of Clinical Chemistry and Laboratory Medicine, Jena University Hospital, Erlanger Allee 101, 07747 Jena, Germany; Center for Sepsis Control and Care (CSCC), Jena University Hospital, Erlanger Allee 101, 07747 Jena, Germany.

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http://dx.doi.org/10.1155/2016/6129437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921625PMC
May 2017

Isoform localization of Dectin-1 regulates the signaling quality of anti-fungal immunity.

Authors:
Mike Fischer Jörg P Müller Bärbel Spies-Weisshart Christine Gräfe Oliver Kurzai Kerstin Hünniger Andreas Hochhaus Sebastian Scholl Ulf Schnetzke

Eur J Immunol 2017 05 13;47(5):848-859. Epub 2017 Apr 13.

Klinik für Innere Medizin II, Abteilung für Hämatologie und Internistische Onkologie, Universitätsklinikum Jena, Jena, Germany.

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http://doi.wiley.com/10.1002/eji.201646849
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http://dx.doi.org/10.1002/eji.201646849DOI Listing
May 2017

Migration and interaction tracking for quantitative analysis of phagocyte-pathogen confrontation assays.

Authors:
Susanne Brandes Stefanie Dietrich Kerstin Hünniger Oliver Kurzai Marc Thilo Figge

Med Image Anal 2017 02 25;36:172-183. Epub 2016 Nov 25.

Applied Systems Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany; Friedrich Schiller University, Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.media.2016.11.007DOI Listing
February 2017

Specific and Novel microRNAs Are Regulated as Response to Fungal Infection in Human Dendritic Cells.

Authors:
Andreas Dix Kristin Czakai Ines Leonhardt Karin Schäferhoff Michael Bonin Reinhard Guthke Hermann Einsele Oliver Kurzai Jürgen Löffler Jörg Linde

Front Microbiol 2017 23;8:270. Epub 2017 Feb 23.

Systems Biology/Bioinformatics, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute Jena, Germany.

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http://dx.doi.org/10.3389/fmicb.2017.00270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322194PMC
February 2017

Lipid Signaling via Pkh1/2 Regulates Fungal CO2 Sensing through the Kinase Sch9.

Authors:
Susann Pohlers Ronny Martin Thomas Krüger Daniela Hellwig Frank Hänel Olaf Kniemeyer Hans Peter Saluz Patrick Van Dijck Joachim F Ernst Axel Brakhage Fritz A Mühlschlegel Oliver Kurzai

MBio 2017 01 31;8(1). Epub 2017 Jan 31.

Septomics Research Center, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute (HKI), Jena, Germany

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http://dx.doi.org/10.1128/mBio.02211-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263247PMC
January 2017

Colonization of CF patients' upper airways with S. aureus contributes more decisively to upper airway inflammation than P. aeruginosa.

Authors:
Wibke Katharina Janhsen Christin Arnold Julia Hentschel Thomas Lehmann Wolfgang Pfister Michael Baier Klas Böer Kerstin Hünniger Oliver Kurzai Uta-Christina Hipler Jochen Georg Mainz

Med Microbiol Immunol 2016 Oct 4;205(5):485-500. Epub 2016 Jul 4.

Department of Pediatrics, Cystic Fibrosis Center, Jena University Hospital, Kochstrasse 2, 07745, Jena, Germany.

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http://dx.doi.org/10.1007/s00430-016-0463-0DOI Listing
October 2016

Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28Day Mortality.

Authors:
André Scherag Franziska Schöneweck Miriam Kesselmeier Stefan Taudien Matthias Platzer Marius Felder Christoph Sponholz Anna Rautanen Adrian V S Hill Charles J Hinds Hamid Hossain Norbert Suttorp Oliver Kurzai Hortense Slevogt Evangelos J Giamarellos-Bourboulis Apostolos Armaganidis Evelyn Trips Markus Scholz Frank M Brunkhorst

EBioMedicine 2016 Oct 15;12:239-246. Epub 2016 Sep 15.

Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany; Center for Clinical Studies, Jena University Hospital, Jena, Germany; Head of Paul-Martini-Clinical Sepsis Research Unit, Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.

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http://dx.doi.org/10.1016/j.ebiom.2016.08.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078589PMC
October 2016

Genetic Factors of the Disease Course After Sepsis: Rare Deleterious Variants Are Predictive.

Authors:
Stefan Taudien Ludwig Lausser Evangelos J Giamarellos-Bourboulis Christoph Sponholz Franziska Schöneweck Marius Felder Lyn-Rouven Schirra Florian Schmid Charalambos Gogos Susann Groth Britt-Sabina Petersen Andre Franke Wolfgang Lieb Klaus Huse Peter F Zipfel Oliver Kurzai Barbara Moepps Peter Gierschik Michael Bauer André Scherag Hans A Kestler Matthias Platzer

EBioMedicine 2016 Oct 15;12:227-238. Epub 2016 Sep 15.

Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.08.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078585PMC
October 2016

Hypoxia attenuates anti-Aspergillus fumigatus immune responses initiated by human dendritic cells.

Authors:
Mirjam Fliesser Marion Wallstein Oliver Kurzai Hermann Einsele Jürgen Löffler

Mycoses 2016 Aug 23;59(8):503-8. Epub 2016 Mar 23.

Medical Clinic and Polyclinic II, University Hospital, Wuerzburg, Germany.

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http://dx.doi.org/10.1111/myc.12498DOI Listing
August 2016

Candida albicans infection leads to barrier breakdown and a MAPK/NF-κB mediated stress response in the intestinal epithelial cell line C2BBe1.

Authors:
Michael Böhringer Susann Pohlers Sylvie Schulze Daniela Albrecht-Eckardt Judith Piegsa Michael Weber Ronny Martin Kerstin Hünniger Jörg Linde Reinhard Guthke Oliver Kurzai

Cell Microbiol 2016 07 26;18(7):889-904. Epub 2016 Feb 26.

Septomics Research Centre, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, Jena, Germany.

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http://dx.doi.org/10.1111/cmi.12566DOI Listing
July 2016

Krüppel-like Factor 4 modulates interleukin-6 release in human dendritic cells after in vitro stimulation with Aspergillus fumigatus and Candida albicans.

Authors:
Kristin Czakai Ines Leonhardt Andreas Dix Michael Bonin Joerg Linde Hermann Einsele Oliver Kurzai Jürgen Loeffler

Sci Rep 2016 06 27;6:27990. Epub 2016 Jun 27.

University Hospital of Würzburg, Department of Internal Medicine II, WÜ4i, Würzburg, Germany.

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http://dx.doi.org/10.1038/srep27990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921831PMC
June 2016

Candida albicans Induces Metabolic Reprogramming in Human NK Cells and Responds to Perforin with a Zinc Depletion Response.

Authors:
Daniela Hellwig Jessica Voigt Maria Bouzani Jürgen Löffler Daniela Albrecht-Eckardt Michael Weber Sascha Brunke Ronny Martin Oliver Kurzai Kerstin Hünniger

Front Microbiol 2016 19;7:750. Epub 2016 May 19.

Septomics Research Center, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute and Friedrich Schiller University Jena, Germany.

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http://dx.doi.org/10.3389/fmicb.2016.00750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872603PMC
May 2016

Candidalysin is a fungal peptide toxin critical for mucosal infection.

Authors:
David L Moyes Duncan Wilson Jonathan P Richardson Selene Mogavero Shirley X Tang Julia Wernecke Sarah Höfs Remi L Gratacap Jon Robbins Manohursingh Runglall Celia Murciano Mariana Blagojevic Selvam Thavaraj Toni M Förster Betty Hebecker Lydia Kasper Gema Vizcay Simona I Iancu Nessim Kichik Antje Häder Oliver Kurzai Ting Luo Thomas Krüger Olaf Kniemeyer Ernesto Cota Oliver Bader Robert T Wheeler Thomas Gutsmann Bernhard Hube Julian R Naglik

Nature 2016 Apr 30;532(7597):64-8. Epub 2016 Mar 30.

Mucosal &Salivary Biology Division, Dental Institute, King's College London SE1 1UL, UK.

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http://dx.doi.org/10.1038/nature17625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851236PMC
April 2016

Host response to Candida albicans bloodstream infection and sepsis.

Authors:
Seána Duggan Ines Leonhardt Kerstin Hünniger Oliver Kurzai

Virulence 2015 18;6(4):316-26. Epub 2015 Mar 18.

a Septomics Research Center ; Friedrich-Schiller-University and Leibniz-Institute for Natural Product Research and Infection Biology-Hans-Knoell-Institute ; Jena , Germany.

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http://dx.doi.org/10.4161/21505594.2014.988096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601378PMC
March 2016

Human Invariant Natural Killer T cells possess immune-modulating functions during Aspergillus infection.

Authors:
Antonia Beitzen-Heineke Maria Bouzani Anna-Lena Schmitt Oliver Kurzai Kerstin Hünniger Hermann Einsele Juergen Loeffler

Med Mycol 2016 Feb 18;54(2):169-76. Epub 2015 Oct 18.

Medizinische Klinik und Poliklinik II, University Hospital Wuerzburg, Wuerzburg, Germany

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http://dx.doi.org/10.1093/mmy/myv074DOI Listing
February 2016

Hypoxia-inducible factor 1α modulates metabolic activity and cytokine release in anti-Aspergillus fumigatus immune responses initiated by human dendritic cells.

Authors:
Mirjam Fliesser Charles Oliver Morton Michael Bonin Frank Ebel Kerstin Hünniger Oliver Kurzai Hermann Einsele Jürgen Löffler

Int J Med Microbiol 2015 Dec 16;305(8):865-73. Epub 2015 Sep 16.

Medical Clinic and Polyclinic II, University Hospital, 97080 Wuerzburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14384221153000
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http://dx.doi.org/10.1016/j.ijmm.2015.08.036DOI Listing
December 2015

Human neutrophils dump Candida glabrata after intracellular killing.

Authors:
Fabian Essig Kerstin Hünniger Stefanie Dietrich Marc Thilo Figge Oliver Kurzai

Fungal Genet Biol 2015 Nov 16;84:37-40. Epub 2015 Sep 16.

Septomics Research Center, Friedrich Schiller University Jena, Leibniz Institute for Natural Product Research and Infection Biology, Hans-Knoell-Institute, Jena, Germany; Center for Sepsis Control and Care, University Hospital Jena, Jena, Germany; German National Reference Center for Invasive Fungal Infections, Hans-Knoell-Institute, Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.fgb.2015.09.008DOI Listing
November 2015

Candida albicans bloodstream isolates in a German university hospital are genetically heterogenous and susceptible to commonly used antifungals.

Authors:
Johanna Huyke Ronny Martin Grit Walther Michael Weber Kerstin Kaerger Marie-Elisabeth Bougnoux Johannes Elias Oliver Kurzai

Int J Med Microbiol 2015 Oct 22;305(7):742-7. Epub 2015 Aug 22.

National Reference Center for Invasive Mycoses, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute, Jena, Germany; Septomics Research Center, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute, Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijmm.2015.08.027DOI Listing
October 2015

Neutrophil activation by Candida glabrata but not Candida albicans promotes fungal uptake by monocytes.

Authors:
Seána Duggan Fabian Essig Kerstin Hünniger Zeinab Mokhtari Laura Bauer Teresa Lehnert Susanne Brandes Antje Häder Ilse D Jacobsen Ronny Martin Marc Thilo Figge Oliver Kurzai

Cell Microbiol 2015 Sep 5;17(9):1259-76. Epub 2015 May 5.

Septomics Research Center, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute, Jena, Germany.

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http://dx.doi.org/10.1111/cmi.12443DOI Listing
September 2015

Bottom-up modeling approach for the quantitative estimation of parameters in pathogen-host interactions.

Authors:
Teresa Lehnert Sandra Timme Johannes Pollmächer Kerstin Hünniger Oliver Kurzai Marc Thilo Figge

Front Microbiol 2015 19;6:608. Epub 2015 Jun 19.

Applied Systems Biology, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute Jena, Germany ; Faculty of Biology and Pharmacy, Friedrich Schiller University Jena Jena, Germany.

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http://dx.doi.org/10.3389/fmicb.2015.00608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473060PMC
July 2015

The fungal quorum-sensing molecule farnesol activates innate immune cells but suppresses cellular adaptive immunity.

Authors:
Ines Leonhardt Steffi Spielberg Michael Weber Daniela Albrecht-Eckardt Markus Bläss Ralf Claus Dagmar Barz Kirstin Scherlach Christian Hertweck Jürgen Löffler Kerstin Hünniger Oliver Kurzai

MBio 2015 Mar 17;6(2):e00143. Epub 2015 Mar 17.

Septomics Research Centre, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute, Jena, Germany

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http://mbio.asm.org/lookup/doi/10.1128/mBio.00143-15
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http://dx.doi.org/10.1128/mBio.00143-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453522PMC
March 2015

Biomarker-based classification of bacterial and fungal whole-blood infections in a genome-wide expression study.

Authors:
Andreas Dix Kerstin Hünniger Michael Weber Reinhard Guthke Oliver Kurzai Jörg Linde

Front Microbiol 2015 11;6:171. Epub 2015 Mar 11.

Systems Biology/Bioinformatics, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute Jena, Germany.

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http://dx.doi.org/10.3389/fmicb.2015.00171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356159PMC
March 2015

Automated segmentation and tracking of non-rigid objects in time-lapse microscopy videos of polymorphonuclear neutrophils.

Authors:
Susanne Brandes Zeinab Mokhtari Fabian Essig Kerstin Hünniger Oliver Kurzai Marc Thilo Figge

Med Image Anal 2015 Feb 8;20(1):34-51. Epub 2014 Nov 8.

Applied Systems Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany; Friedrich Schiller University, Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.media.2014.10.002DOI Listing
February 2015

A second stimulus required for enhanced antifungal activity of human neutrophils in blood is provided by anaphylatoxin C5a.

Authors:
Kerstin Hünniger Kristin Bieber Ronny Martin Teresa Lehnert Marc Thilo Figge Jürgen Löffler Ren-Feng Guo Niels C Riedemann Oliver Kurzai

J Immunol 2015 Feb 24;194(3):1199-210. Epub 2014 Dec 24.

Septomics Research Center, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute, 07745 Jena, Germany; Center for Sepsis Control and Care, Jena University Hospital, 07747 Jena, Germany; and German National Reference Center for Invasive Fungal Infections, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute, 07745 Jena, Germany

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1401845
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February 2015

Defining the transcriptomic landscape of Candida glabrata by RNA-Seq.

Authors:
Jörg Linde Seána Duggan Michael Weber Fabian Horn Patricia Sieber Daniela Hellwig Konstantin Riege Manja Marz Ronny Martin Reinhard Guthke Oliver Kurzai

Nucleic Acids Res 2015 Feb 13;43(3):1392-406. Epub 2015 Jan 13.

Septomics Research Center, Fungal Septomics, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute, Jena, Germany National Reference Center for Invasive Mycoses, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute, Jena, Germany.

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http://dx.doi.org/10.1093/nar/gku1357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330350PMC
February 2015

Neutrophil responses to aspergillosis: new roles for old players.

Authors:
Cristina Cunha Oliver Kurzai Jürgen Löffler Franco Aversa Luigina Romani Agostinho Carvalho

Mycopathologia 2014 Dec 9;178(5-6):387-93. Epub 2014 Aug 9.

Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal.

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http://dx.doi.org/10.1007/s11046-014-9796-7DOI Listing
December 2014

Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant.

Authors:
Anja Wartenberg Jörg Linde Ronny Martin Maria Schreiner Fabian Horn Ilse D Jacobsen Sabrina Jenull Thomas Wolf Karl Kuchler Reinhard Guthke Oliver Kurzai Anja Forche Christophe d'Enfert Sascha Brunke Bernhard Hube

PLoS Genet 2014 Dec 4;10(12):e1004824. Epub 2014 Dec 4.

Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute Jena (HKI), Jena, Germany; Integrated Research and Treatment Center, Sepsis und Sepsisfolgen, Center for Sepsis Control and Care (CSCC), Universitätsklinikum Jena, Germany; Friedrich Schiller University, Jena, Germany.

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https://dx.plos.org/10.1371/journal.pgen.1004824
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http://dx.doi.org/10.1371/journal.pgen.1004824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256171PMC
December 2014

Human dendritic cell subsets display distinct interactions with the pathogenic mould Aspergillus fumigatus.

Authors:
Jasmin Lother Tanja Breitschopf Sven Krappmann C Oliver Morton Maria Bouzani Oliver Kurzai Matthias Gunzer Mike Hasenberg Hermann Einsele Juergen Loeffler

Int J Med Microbiol 2014 Nov 18;304(8):1160-8. Epub 2014 Aug 18.

Laboratory WÜ4i, Medical Clinic and Policlinic II, University Clinic Würzburg, Würzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijmm.2014.08.009DOI Listing
November 2014

In vivo imaging of disseminated murine Candida albicans infection reveals unexpected host sites of fungal persistence during antifungal therapy.

Authors:
Ilse D Jacobsen Anja Lüttich Oliver Kurzai Bernhard Hube Matthias Brock

J Antimicrob Chemother 2014 Oct 20;69(10):2785-96. Epub 2014 Jun 20.

Friedrich Schiller University, Jena, Germany Microbial Biochemistry and Physiology, Hans Knoell Institute, Leibniz Institute for Natural Product Research and Infection Biology, Beutenbergstrasse 11a, 07745 Jena, Germany

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http://dx.doi.org/10.1093/jac/dku198DOI Listing
October 2014

Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation.

Authors:
Michael Liembo Ekaney Gordon Philipp Otto Maik Sossdorf Christoph Sponholz Michael Boehringer Wolfgang Loesche Daniel Rittirsch Arne Wilharm Oliver Kurzai Michael Bauer Ralf Alexander Claus

Crit Care 2014 Sep 24;18(5):543. Epub 2014 Sep 24.

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http://dx.doi.org/10.1186/s13054-014-0543-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201918PMC
September 2014

Differential role of NK cells against Candida albicans infection in immunocompetent or immunocompromised mice.

Authors:
Jessica Quintin Jessica Voigt Robbert van der Voort Ilse D Jacobsen Ineke Verschueren Bernhard Hube Evangelos J Giamarellos-Bourboulis Jos W M van der Meer Leo A B Joosten Oliver Kurzai Mihai G Netea

Eur J Immunol 2014 Aug 27;44(8):2405-14. Epub 2014 May 27.

Department of Internal Medicine, Radboud Center for Infectious Disease, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/eji.201343828DOI Listing
August 2014

Aspergillus fumigatus induces microRNA-132 in human monocytes and dendritic cells.

Authors:
Mithun Das Gupta Mirjam Fliesser Jan Springer Tanja Breitschopf Hannes Schlossnagel Anna-Lena Schmitt Oliver Kurzai Kerstin Hünniger Hermann Einsele Jürgen Löffler

Int J Med Microbiol 2014 Jul 26;304(5-6):592-6. Epub 2014 Apr 26.

University Hospital Wuerzburg, Medical Clinic and Polyclinic II, Wuerzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijmm.2014.04.005DOI Listing
July 2014

A family of glutathione peroxidases contributes to oxidative stress resistance in Candida albicans.

Authors:
Pedro Miramón Christine Dunker Lydia Kasper Ilse D Jacobsen Dagmar Barz Oliver Kurzai Bernhard Hube

Med Mycol 2014 Apr 7;52(3):223-39. Epub 2014 Mar 7.

Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology.

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http://dx.doi.org/10.1093/mmy/myt021DOI Listing
April 2014

PTX3 deficiency and aspergillosis.

Authors:
Cristina Cunha Oliver Kurzai Agostinho Carvalho

N Engl J Med 2014 04;370(17):1666-7

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http://dx.doi.org/10.1056/NEJMc1402787DOI Listing
April 2014

Human natural killer cells acting as phagocytes against Candida albicans and mounting an inflammatory response that modulates neutrophil antifungal activity.

Authors:
Jessica Voigt Kerstin Hünniger Maria Bouzani Ilse D Jacobsen Dagmar Barz Bernhard Hube Jürgen Löffler Oliver Kurzai

J Infect Dis 2014 Feb 25;209(4):616-26. Epub 2013 Oct 25.

Septomics Research Centre, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute.

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http://dx.doi.org/10.1093/infdis/jit574DOI Listing
February 2014

Influences of nasal lavage collection-, processing- and storage methods on inflammatory markers--evaluation of a method for non-invasive sampling of epithelial lining fluid in cystic fibrosis and other respiratory diseases.

Authors:
Julia Hentschel Ulrike Müller Franziska Doht Nele Fischer Klas Böer Jürgen Sonnemann Christina Hipler Kerstin Hünniger Oliver Kurzai Udo R Markert Jochen G Mainz

J Immunol Methods 2014 Feb 23;404:41-51. Epub 2013 Dec 23.

CF-Center, Pediatrics, Jena University Hospital, Germany.

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http://dx.doi.org/10.1016/j.jim.2013.12.003DOI Listing
February 2014

A virtual infection model quantifies innate effector mechanisms and Candida albicans immune escape in human blood.

Authors:
Kerstin Hünniger Teresa Lehnert Kristin Bieber Ronny Martin Marc Thilo Figge Oliver Kurzai

PLoS Comput Biol 2014 Feb 20;10(2):e1003479. Epub 2014 Feb 20.

Septomics Research Center, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute (HKI), Jena, Germany.

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http://dx.doi.org/10.1371/journal.pcbi.1003479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930496PMC
February 2014

Genetic PTX3 deficiency and aspergillosis in stem-cell transplantation.

Authors:
Cristina Cunha Franco Aversa João F Lacerda Alessandro Busca Oliver Kurzai Matthias Grube Jürgen Löffler Johan A Maertens Alain S Bell Antonio Inforzato Elisa Barbati Bruno Almeida Pedro Santos e Sousa Anna Barbui Leonardo Potenza Morena Caira Fernando Rodrigues Giovanni Salvatori Livio Pagano Mario Luppi Alberto Mantovani Andrea Velardi Luigina Romani Agostinho Carvalho

N Engl J Med 2014 Jan;370(5):421-32

The authors' affiliations are listed in the Appendix.

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http://dx.doi.org/10.1056/NEJMoa1211161DOI Listing
January 2014

A case for case reports-And a new publishing platform for clinical mycology.

Authors:
Oliver Kurzai Neil Gow

Med Mycol Case Rep 2012 28;1(1):17-8. Epub 2012 Mar 28.

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http://dx.doi.org/10.1016/j.mmcr.2012.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854618PMC
December 2013

Complement and innate immune evasion strategies of the human pathogenic fungus Candida albicans.

Authors:
Shanshan Luo Christine Skerka Oliver Kurzai Peter F Zipfel

Mol Immunol 2013 Dec 26;56(3):161-9. Epub 2013 Jun 26.

Department of Infection Biology, Leibniz Institute for Natural Products Research and Infection Biology, Hans-Knöll Institute, Jena, Germany.

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http://dx.doi.org/10.1016/j.molimm.2013.05.218DOI Listing
December 2013

A core filamentation response network in Candida albicans is restricted to eight genes.

Authors:
Ronny Martin Daniela Albrecht-Eckardt Sascha Brunke Bernhard Hube Kerstin Hünniger Oliver Kurzai

PLoS One 2013 14;8(3):e58613. Epub 2013 Mar 14.

Septomics Research Center, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute, Jena, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0058613PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597736PMC
September 2013

Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress.

Authors:
Pedro Miramón Christine Dunker Hanna Windecker Iryna M Bohovych Alistair J P Brown Oliver Kurzai Bernhard Hube

PLoS One 2012 21;7(12):e52850. Epub 2012 Dec 21.

Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology, Hans-Knoell-Institute, Jena, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052850PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528649PMC
July 2013

Carbonic anhydrase regulation and CO(2) sensing in the fungal pathogen Candida glabrata involves a novel Rca1p ortholog.

Authors:
Fabien Cottier Worraanong Leewattanapasuk Laura R Kemp Mariana Murphy Claudiu T Supuran Oliver Kurzai Fritz A Mühlschlegel

Bioorg Med Chem 2013 Mar 6;21(6):1549-54. Epub 2012 Jun 6.

School of Biosciences, University of Kent, Canterbury, United Kingdom.

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http://dx.doi.org/10.1016/j.bmc.2012.05.053DOI Listing
March 2013

Poplar extrafloral nectar is protected against plant and human pathogenic fungus.

Authors:
María Escalante-Pérez Mario Jaborsky Jörg Reinders Oliver Kurzai Rainer Hedrich Peter Ache

Mol Plant 2012 Sep 2;5(5):1157-9. Epub 2012 Aug 2.

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http://dx.doi.org/10.1093/mp/sss072DOI Listing
September 2012

40-O -[2-Hydroxyethyl]rapamycin modulates human dendritic cell function during exposure to Aspergillus fumigatus.

Authors:
Ruth Bauer Markus Mezger Christian Blockhaus Anna-Lena Schmitt Oliver Kurzai Hermann Einsele Juergen Loeffler

J Basic Microbiol 2012 Jun 21;52(3):269-76. Epub 2011 Jul 21.

Universität Würzburg, Medizinische Klinik & Poliklinik II, Würzburg, Germany.

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http://dx.doi.org/10.1002/jobm.201100071DOI Listing
June 2012

The Arthroderma benhamiae hydrophobin HypA mediates hydrophobicity and influences recognition by human immune effector cells.

Authors:
Christoph Heddergott Sandra Bruns Sandor Nietzsche Ines Leonhardt Oliver Kurzai Olaf Kniemeyer Axel A Brakhage

Eukaryot Cell 2012 May 9;11(5):673-82. Epub 2012 Mar 9.

Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany.

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http://dx.doi.org/10.1128/EC.00037-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346419PMC
May 2012

The bZIP transcription factor Rca1p is a central regulator of a novel CO₂ sensing pathway in yeast.

Authors:
Fabien Cottier Martine Raymond Oliver Kurzai Marianne Bolstad Worraanong Leewattanapasuk Claudia Jiménez-López Michael C Lorenz Dominique Sanglard Libuše Váchová Norman Pavelka Zdena Palková Fritz A Mühlschlegel

PLoS Pathog 2012 Jan 12;8(1):e1002485. Epub 2012 Jan 12.

School of Biosciences, University of Kent, Canterbury, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.1002485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257301PMC
January 2012

Human NK cells display important antifungal activity against Aspergillus fumigatus, which is directly mediated by IFN-γ release.

Authors:
Maria Bouzani Michael Ok Allison McCormick Frank Ebel Oliver Kurzai C Oliver Morton Hermann Einsele Juergen Loeffler

J Immunol 2011 Aug 22;187(3):1369-76. Epub 2011 Jun 22.

Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, 97080 Würzburg, Germany.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1003593
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http://dx.doi.org/10.4049/jimmunol.1003593DOI Listing
August 2011

Real-time PCR and quantitative culture for monitoring of experimental Aspergillus fumigatus intracranial infection in neutropenic mice.

Authors:
C Oliver Morton Karl V Clemons Jan Springer Justus G Mueller Thomas R Rogers David A Stevens Oliver Kurzai Hermann Einsele Juergen Loeffler

J Med Microbiol 2011 Jul 24;60(Pt 7):913-9. Epub 2011 Mar 24.

Department of Clinical Microbiology, Sir Patrick Dun Research Laboratory, School of Medicine, Trinity College Dublin, Dublin, Ireland.

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http://jmm.microbiologyresearch.org/content/journal/jmm/10.1
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http://dx.doi.org/10.1099/jmm.0.028399-0DOI Listing
July 2011

Neisseria meningitidis adhesin NadA targets beta1 integrins: functional similarity to Yersinia invasin.

Authors:
Virginie Nägele Jürgen Heesemann Stephanie Schielke Luisa F Jiménez-Soto Oliver Kurzai Nikolaus Ackermann

J Biol Chem 2011 Jun 6;286(23):20536-46. Epub 2011 Apr 6.

Max von Pettenkofer Institute for Hygiene and Medical Microbiology, Ludwig Maximilians University Munich, 80336 Munich, Germany.

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http://dx.doi.org/10.1074/jbc.M110.188326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121457PMC
June 2011

[Ulcerating nodules on the right arm after hunting muskrats].

Authors:
Andreas Kerstan Ana-M Wendel Oliver Kurzai Eva-B Bröcker Annette Kolb-Mäurer

J Dtsch Dermatol Ges 2011 Jun;9(6):487-9

Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universität Würzburg.

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http://doi.wiley.com/10.1111/j.1610-0387.2011.07697.x
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http://dx.doi.org/10.1111/j.1610-0387.2011.07697.xDOI Listing
June 2011

Pathogen-specific DNA enrichment does not increase sensitivity of PCR for diagnosis of invasive aspergillosis in neutropenic patients.

Authors:
Jan Springer Juergen Loeffler Werner Heinz Hannes Schlossnagel Marc Lehmann Oliver Morton Thomas R Rogers Corinna Schmitt Matthias Frosch Hermann Einsele Oliver Kurzai

J Clin Microbiol 2011 Apr 29;49(4):1267-73. Epub 2010 Dec 29.

Universität Würzburg, Medizinische Klinik und Poliklinik II, Würzburg, Germany.

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http://dx.doi.org/10.1128/JCM.01679-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122848PMC
April 2011

Characterization of FarR as a highly specialized, growth phase-dependent transcriptional regulator in Neisseria meningitidis.

Authors:
Stephanie Schielke Carolin Spatz Roland Felix Schwarz Biju Joseph Christoph Schoen Sabine Marita Schulz Kerstin Hubert Matthias Frosch Alexandra Schubert-Unkmeir Oliver Kurzai

Int J Med Microbiol 2011 Apr 2;301(4):325-33. Epub 2011 Feb 2.

University of Würzburg, Institute of Hygiene and Microbiology, Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2010.11.007DOI Listing
April 2011

The Candida albicans-specific gene EED1 encodes a key regulator of hyphal extension.

Authors:
Ronny Martin Gary P Moran Ilse D Jacobsen Antje Heyken Jenny Domey Derek J Sullivan Oliver Kurzai Bernhard Hube

PLoS One 2011 Apr 7;6(4):e18394. Epub 2011 Apr 7.

Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute, Jena, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0018394PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075580PMC
April 2011

The temporal dynamics of differential gene expression in Aspergillus fumigatus interacting with human immature dendritic cells in vitro.

Authors:
Charles O Morton John J Varga Anke Hornbach Markus Mezger Helga Sennefelder Susanne Kneitz Oliver Kurzai Sven Krappmann Hermann Einsele William C Nierman Thomas R Rogers Juergen Loeffler

PLoS One 2011 Jan 14;6(1):e16016. Epub 2011 Jan 14.

Department of Clinical Microbiology, Trinity College Dublin, Dublin, Ireland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0016016PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021540PMC
January 2011

Medical microbiology.

Authors:
Oliver Kurzai Erika Kothe

J Basic Microbiol 2010 Dec;50 Suppl 1:S3

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http://dx.doi.org/10.1002/jobm.201090014DOI Listing
December 2010

Virulence determinants involved in differential host niche adaptation of Neisseria meningitidis and Neisseria gonorrhoeae.

Authors:
Stephanie Schielke Matthias Frosch Oliver Kurzai

Med Microbiol Immunol 2010 Aug 9;199(3):185-96. Epub 2010 Apr 9.

Institute of Hygiene and Microbiology, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1007/s00430-010-0150-5DOI Listing
August 2010

Role of glycogen synthase kinase 3 (GSK-3) in innate immune response of human immature dendritic cells to Aspergillus fumigatus.

Authors:
Katrin Spinnler Markus Mezger Michael Steffens Helga Sennefelder Oliver Kurzai Hermann Einsele Juergen Loeffler

Med Mycol 2010 Jun;48(4):589-97

Universität Würzburg, Medizinische Klinik & Poliklinik II, Germany.

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http://dx.doi.org/10.3109/13693780903420625DOI Listing
June 2010

The transcriptional repressor FarR is not involved in meningococcal fatty acid resistance mediated by the FarAB efflux pump and dependent on lipopolysaccharide structure.

Authors:
Stephanie Schielke Corinna Schmitt Carolin Spatz Matthias Frosch Alexandra Schubert-Unkmeir Oliver Kurzai

Appl Environ Microbiol 2010 May 26;76(10):3160-9. Epub 2010 Mar 26.

University of Würzburg, Institute of Hygiene and Microbiology, Würzburg, Germany.

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http://dx.doi.org/10.1128/AEM.02833-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869119PMC
May 2010

Eradication is impossible.

Authors:
Oliver Kurzai

Dtsch Arztebl Int 2010 May 28;107(21):369; author reply 369-70. Epub 2010 May 28.

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https://www.aerzteblatt.de/10.3238/arztebl.2010.0369a
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http://dx.doi.org/10.3238/arztebl.2010.0369aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883280PMC
May 2010

The glycosylphosphatidylinositol-anchored protease Sap9 modulates the interaction of Candida albicans with human neutrophils.

Authors:
Anke Hornbach Antje Heyken Lydia Schild Bernhard Hube Jürgen Löffler Oliver Kurzai

Infect Immun 2009 Dec 5;77(12):5216-24. Epub 2009 Oct 5.

Institute of Hygiene and Microbiology, University of Würzburg, 97080 Würzburg, Germany.

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http://iai.asm.org/cgi/doi/10.1128/IAI.00723-09
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http://dx.doi.org/10.1128/IAI.00723-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786460PMC
December 2009

Immune responses of human immature dendritic cells can be modulated by the recombinant Aspergillus fumigatus antigen Aspf1.

Authors:
Michael Ok Jean Paul Latgé Carina Baeuerlein Frank Ebel Markus Mezger Max Topp Oliver Kurzai Doreen Killian Markus Kapp Goetz-Ulrich Grigoleit Helga Sennefelder Javier Arroyo Hermann Einsele Juergen Loeffler

Clin Vaccine Immunol 2009 Oct 12;16(10):1485-92. Epub 2009 Aug 12.

Universität Würzburg, Medizinische Klinik & Poliklinik II, Institut für Hygiene & Mikrobiologie, Würzburg, Germany.

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http://dx.doi.org/10.1128/CVI.00175-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756848PMC
October 2009

Recognition via the class A scavenger receptor modulates cytokine secretion by human dendritic cells after contact with Neisseria meningitidis.

Authors:
Andrea Villwock Corinna Schmitt Stephanie Schielke Matthias Frosch Oliver Kurzai

Microbes Infect 2008 Aug-Sep;10(10-11):1158-65. Epub 2008 Jun 29.

Institute of Hygiene and Microbiology, University of Wuerzburg, Josef-Schneider-Str. 2/E1, 97080 Wuerzburg, Germany.

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http://dx.doi.org/10.1016/j.micinf.2008.06.009DOI Listing
July 2009

Expression of the meningococcal adhesin NadA is controlled by a transcriptional regulator of the MarR family.

Authors:
Stephanie Schielke Claudia Huebner Carolin Spatz Virginie Nägele Nikolaus Ackermann Matthias Frosch Oliver Kurzai Alexandra Schubert-Unkmeir

Mol Microbiol 2009 May 21;72(4):1054-67. Epub 2009 Apr 21.

University of Würzburg, Institute of Hygiene and Microbiology, Würzburg, Germany.

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http://dx.doi.org/10.1111/j.1365-2958.2009.06710.xDOI Listing
May 2009

Recognition of meningococcal molecular patterns by innate immune receptors.

Authors:
Corinna Schmitt Andrea Villwock Oliver Kurzai

Int J Med Microbiol 2009 Jan 15;299(1):9-20. Epub 2008 Aug 15.

Institute of Hygiene and Microbiology, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2008.06.007DOI Listing
January 2009

Evaluation of new colorimetric vitek 2 yeast identification card by use of different source media.

Authors:
Giuseppe Valenza Jörn Strasen Frauke Schäfer Matthias Frosch Oliver Kurzai Marianne Abele-Horn

J Clin Microbiol 2008 Nov 17;46(11):3784-7. Epub 2008 Sep 17.

Institute of Hygiene and Microbiology, University of Würzburg, Josef-Schneider-Str. 2/E1, 97080 Würzburg, Germany.

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http://dx.doi.org/10.1128/JCM.01318-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576618PMC
November 2008

Capsule acetylation does not impair recognition of serogroup C, W-135 and Y meningococci by human dendritic cells.

Authors:
Andrea Villwock Corinna Schmitt Matthias Frosch Oliver Kurzai

Int J Med Microbiol 2008 Oct 31;298(7-8):591-7. Epub 2007 Dec 31.

Institute of Hygiene and Microbiology, University of Würzburg, Josef-Schneider-Str. 2/E1, D-97080 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2007.11.003DOI Listing
October 2008

Impact of mycophenolic acid on the functionality of human polymorphonuclear neutrophils and dendritic cells during interaction with Aspergillus fumigatus.

Authors:
Markus Mezger Iwona Wozniok Christian Blockhaus Oliver Kurzai Holger Hebart Hermann Einsele Juergen Loeffler

Antimicrob Agents Chemother 2008 Jul 21;52(7):2644-6. Epub 2008 Apr 21.

Medizinische Klinik II, Universität Würzburg, 97070 Würzburg, Germany.

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http://dx.doi.org/10.1128/AAC.01618-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443887PMC
July 2008

Induction of ERK-kinase signalling triggers morphotype-specific killing of Candida albicans filaments by human neutrophils.

Authors:
Iwona Wozniok Anke Hornbach Corinna Schmitt Matthias Frosch Hermann Einsele Bernhard Hube Jürgen Löffler Oliver Kurzai

Cell Microbiol 2008 Mar 21;10(3):807-20. Epub 2007 Nov 21.

University of Würzburg, Department of Internal Medicine II, Germany.

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http://dx.doi.org/10.1111/j.1462-5822.2007.01086.xDOI Listing
March 2008

Proinflammatory response of immature human dendritic cells is mediated by dectin-1 after exposure to Aspergillus fumigatus germ tubes.

Authors:
Markus Mezger Susanne Kneitz Iwona Wozniok Oliver Kurzai Hermann Einsele Juergen Loeffler

J Infect Dis 2008 Mar;197(6):924-31

Medizinische Klinik und Poliklinik II, Würzburg, Germany.

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https://academic.oup.com/jid/article-lookup/doi/10.1086/5286
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http://dx.doi.org/10.1086/528694DOI Listing
March 2008

Whole-genome comparison of disease and carriage strains provides insights into virulence evolution in Neisseria meningitidis.

Authors:
Christoph Schoen Jochen Blom Heike Claus Anja Schramm-Glück Petra Brandt Tobias Müller Alexander Goesmann Biju Joseph Sebastian Konietzny Oliver Kurzai Corinna Schmitt Torben Friedrich Burkhard Linke Ulrich Vogel Matthias Frosch

Proc Natl Acad Sci U S A 2008 Mar 27;105(9):3473-8. Epub 2008 Feb 27.

Institute for Hygiene and Microbiology, University of Würzburg, Josef-Schneider-Strasse 2, 97080 Würzburg, Germany.

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http://dx.doi.org/10.1073/pnas.0800151105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265139PMC
March 2008

The Aspergillus fumigatus transcriptional regulator AfYap1 represents the major regulator for defense against reactive oxygen intermediates but is dispensable for pathogenicity in an intranasal mouse infection model.

Authors:
Franziska Lessing Olaf Kniemeyer Iwona Wozniok Juergen Loeffler Oliver Kurzai Albert Haertl Axel A Brakhage

Eukaryot Cell 2007 Dec 5;6(12):2290-302. Epub 2007 Oct 5.

Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology-Hans-Knoell-Institute, Jena, Germany.

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http://dx.doi.org/10.1128/EC.00267-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168236PMC
December 2007

A functional two-partner secretion system contributes to adhesion of Neisseria meningitidis to epithelial cells.

Authors:
Corinna Schmitt David Turner Maria Boesl Marion Abele Matthias Frosch Oliver Kurzai

J Bacteriol 2007 Nov 14;189(22):7968-76. Epub 2007 Sep 14.

University of Wuerzburg, Institute of Hygiene and Microbiology, Josef-Schneider-Str. 2, E1, 97080 Wuerzburg, Germany.

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http://dx.doi.org/10.1128/JB.00851-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168671PMC
November 2007

Cytosolic proteins contribute to surface plasminogen recruitment of Neisseria meningitidis.

Authors:
Andreas Knaust Martin V R Weber Sven Hammerschmidt Simone Bergmann Matthias Frosch Oliver Kurzai

J Bacteriol 2007 Apr 16;189(8):3246-55. Epub 2007 Feb 16.

Institute of Hygiene and Environmental Medicine, University of Giessen, Friedrichsstrasse 16, 35392 Giessen, Germany.

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http://dx.doi.org/10.1128/JB.01966-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855851PMC
April 2007

[Persistent reddish-brown plaque on the occiput of a 62-year-old patient].

Authors:
Johanna Stoevesandt Oliver Kurzai Eva-B Bröcker Henning Hamm

J Dtsch Dermatol Ges 2007 Jan;5(1):55-7

Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Bayerische Julius-Maximilians-Universität Würzburg, Germany.

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http://dx.doi.org/10.1111/j.1610-0387.2007.06195.xDOI Listing
January 2007