Publications by authors named "Oliver J Brand"

27Publications

Neurturin regulates the lung-resident macrophage inflammatory response to viral infection.

Authors:
Emma Connolly David J Morgan Miriam Franklin Angela Simpson Rajesh Shah Oliver J Brand Christopher P Jagger Joshua Casulli Karishma Mohamed Aleksander M Grabiec Tracy Hussell

Life Sci Alliance 2020 12 5;3(12). Epub 2020 Oct 5.

The Lydia Becker Institute for Immunology and Inflammation, The University of Manchester, Manchester, UK

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December 2020

Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases.

Authors:
Naoya Fujino Oliver J Brand David J Morgan Toshifumi Fujimori Aleksander M Grabiec Christopher P Jagger Rose A Maciewicz Mitsuhiro Yamada Koji Itakura Hisatoshi Sugiura Masakazu Ichinose Tracy Hussell

J Exp Med 2019 09 9;216(9):2184-2201. Epub 2019 Jul 9.

Manchester Collaborative Centre for Inflammation Research, the University of Manchester, Manchester, UK

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September 2019

Innate Immune Cell Suppression and the Link With Secondary Lung Bacterial Pneumonia.

Authors:
David J Morgan Joshua Casulli Christine Chew Emma Connolly Sylvia Lui Oliver J Brand Rizwana Rahman Christopher Jagger Tracy Hussell

Front Immunol 2018 14;9:2943. Epub 2018 Dec 14.

Manchester Collaborative Centre for Inflammation Research, The Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, United Kingdom.

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October 2019

Defective lung function following influenza virus is due to prolonged, reversible hyaluronan synthesis.

Authors:
Thomas J Bell Oliver J Brand David J Morgan Samira Salek-Ardakani Christopher Jagger Toshifumi Fujimori Lauren Cholewa Viranga Tilakaratna Jörgen Östling Matt Thomas Anthony J Day Robert J Snelgrove Tracy Hussell

Matrix Biol 2019 07 20;80:14-28. Epub 2018 Jun 20.

Manchester Collaborative Centre for Inflammation Research, University of Manchester, UK. Electronic address:

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July 2019

Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation.

Authors:
Alice Pasini Oliver J Brand Gisli Jenkins Alan J Knox Linhua Pang

Biochim Biophys Acta Gene Regul Mech 2018 May 17;1861(5):463-472. Epub 2018 Mar 17.

Division of Respiratory Medicine, University of Nottingham School of Medicine, City Hospital, Nottingham NG5 1PB, United Kingdom. Electronic address:

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May 2018

Interplay between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis.

Authors:
William R Coward Oliver J Brand Alice Pasini Gisli Jenkins Alan J Knox Linhua Pang

Am J Respir Cell Mol Biol 2018 04;58(4):449-460

1 Division of Respiratory Medicine and.

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April 2018

Transforming Growth Factor-β and Interleukin-1β Signaling Pathways Converge on the Chemokine CCL20 Promoter.

Authors:
Oliver J Brand Sangeeta Somanath Catherine Moermans Haruhiko Yanagisawa Mitsuo Hashimoto Stephanie Cambier Jennifer Markovics Andrew J Bondesson Arthur Hill David Jablons Paul Wolters Jianlong Lou James D Marks Jody L Baron Stephen L Nishimura

J Biol Chem 2015 Jun 27;290(23):14717-28. Epub 2015 Apr 27.

From the Departments of Pathology,

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June 2015

Selective targeting of TGF-β activation to treat fibroinflammatory airway disease.

Authors:
Shunsuke Minagawa Jianlong Lou Robert I Seed Anthony Cormier Shenping Wu Yifan Cheng Lynne Murray Ping Tsui Jane Connor Ronald Herbst Cedric Govaerts Tyren Barker Stephanie Cambier Haruhiko Yanagisawa Amanda Goodsell Mitsuo Hashimoto Oliver J Brand Ran Cheng Royce Ma Kate J McKnelly Weihua Wen Arthur Hill David Jablons Paul Wolters Hideya Kitamura Jun Araya Andrea J Barczak David J Erle Louis F Reichardt James D Marks Jody L Baron Stephen L Nishimura

Sci Transl Med 2014 Jun;6(241):241ra79

Department of Pathology, University of California, San Francisco, San Francisco, CA 94110, USA.

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June 2014

Skewed X chromosome inactivation and female preponderance in autoimmune thyroid disease: an association study and meta-analysis.

Authors:
Matthew J Simmonds Fotini K Kavvoura Oliver J Brand Paul R Newby Laura E Jackson Chantal E Hargreaves Jayne A Franklyn Stephen C L Gough

J Clin Endocrinol Metab 2014 Jan 20;99(1):E127-31. Epub 2013 Dec 20.

Oxford Centre for Diabetes, Endocrinology, and Metabolism (M.J.S., F.K.K., O.J.B., S.C.L.G.) and Oxford National Institute for Health Research Biomedical Research Centre (F.K.K., S.C.L.G.), Churchill Hospital, Headington, Oxford OX3 7LJ, United Kingdom; and Centre for Endocrinology, Diabetes, and Metabolism (P.R.N., L.E.J., C.E.H., J.A.F.), School of Clinical and Experimental Medicine, College of Medical and Dental Science, Institute of Biomedical Research, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.

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January 2014

Skewing of female X-chromosome inactivation: an epigenetic risk factor for kidney transplantation outcome.

Authors:
Matthew J Simmonds David Benavente Oliver J Brand Jason Moore Simon Ball Charles J Ferro David Briggs Stephen C L Gough Richard J Borrows

Transplantation 2013 Mar;95(5):e25-8

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March 2013

Donor ABCB1 variant associates with increased risk for kidney allograft failure.

Authors:
Jason Moore Amy Jayne McKnight Bernd Döhler Matthew J Simmonds Aisling E Courtney Oliver J Brand David Briggs Simon Ball Paul Cockwell Christopher C Patterson Alexander P Maxwell Stephen C L Gough Gerhard Opelz Richard Borrows

J Am Soc Nephrol 2012 Nov 11;23(11):1891-9. Epub 2012 Oct 11.

Department of Nephrology and Kidney Transplantation, Queen Elizabeth Hospital, Birmingham, B15 2WB, United Kingdom.

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November 2012

Seven newly identified loci for autoimmune thyroid disease.

Authors:
Jason D Cooper Matthew J Simmonds Neil M Walker Oliver Burren Oliver J Brand Hui Guo Chris Wallace Helen Stevens Gillian Coleman Jayne A Franklyn John A Todd Stephen C L Gough

Hum Mol Genet 2012 Dec 24;21(23):5202-8. Epub 2012 Aug 24.

Department of Medical Genetics, Cambridge Institute for Medical Research, Juvenile Diabetes Research Foundation/ Wellcome Trust Diabetes and Inflammation Laboratory, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK.

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December 2012

Immunogenetic mechanisms leading to thyroid autoimmunity: recent advances in identifying susceptibility genes and regions.

Authors:
Oliver J Brand Stephen C L Gough

Curr Genomics 2011 Dec;12(8):526-41

Oxford Centre for Diabetes Endocrinology and Metabolism (OCDEM), Oxford, UK.

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December 2011

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry.

Authors:
Karen A Hunt Deborah J Smyth Tobias Balschun Maria Ban Vanisha Mistry Tariq Ahmad Vidya Anand Jeffrey C Barrett Leena Bhaw-Rosun Nicholas A Bockett Oliver J Brand Elisabeth Brouwer Patrick Concannon Jason D Cooper Kerith-Rae M Dias Cleo C van Diemen Patrick C Dubois Sarah Edkins Regina Fölster-Holst Karin Fransen David N Glass Graham A R Heap Sylvia Hofmann Tom W J Huizinga Sarah Hunt Cordelia Langford James Lee John Mansfield Maria Giovanna Marrosu Christopher G Mathew Charles A Mein Joachim Müller-Quernheim Sarah Nutland Suna Onengut-Gumuscu Willem Ouwehand Kerra Pearce Natalie J Prescott Marcel D Posthumus Simon Potter Giulio Rosati Jennifer Sambrook Jack Satsangi Stefan Schreiber Corina Shtir Matthew J Simmonds Marc Sudman Susan D Thompson Rene Toes Gosia Trynka Timothy J Vyse Neil M Walker Stephan Weidinger Alexandra Zhernakova Magdalena Zoledziewska Rinse K Weersma Stephen C L Gough Stephen Sawcer Cisca Wijmenga Miles Parkes Francesco Cucca Andre Franke Panos Deloukas Stephen S Rich John A Todd David A van Heel

Nat Genet 2011 Dec 27;44(1):3-5. Epub 2011 Dec 27.

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December 2011

Copy number variation in common disease.

Authors:
Oliver J Brand Stephen C L Gough

Thyroid 2011 Jan;21(1):1-4

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January 2011

Thyroid stimulating hormone receptor (TSHR) intron 1 variants are major risk factors for Graves' disease in three European Caucasian cohorts.

Authors:
Rafał Płoski Oliver J Brand Beata Jurecka-Lubieniecka Maria Franaszczyk Dorota Kula Paweł Krajewski Muhammad A Karamat Matthew J Simmonds Jayne A Franklyn Stephen C L Gough Barbara Jarząb Tomasz Bednarczuk

PLoS One 2010 Nov 25;5(11):e15512. Epub 2010 Nov 25.

Department of Medical Genetics, Medical University of Warsaw, Warsaw, Poland.

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November 2010

Association of Fc receptor-like 5 (FCRL5) with Graves' disease is secondary to the effect of FCRL3.

Authors:
Matthew J Simmonds Oliver J Brand Jeffrey C Barrett Paul R Newby Jayne A Franklyn Stephen C L Gough

Clin Endocrinol (Oxf) 2010 Nov;73(5):654-60

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Headington, Oxford, UK.

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November 2010

Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease.

Authors:
Elaine F Remmers Fulya Cosan Yohei Kirino Michael J Ombrello Neslihan Abaci Colleen Satorius Julie M Le Barbara Yang Benjamin D Korman Aris Cakiris Oznur Aglar Zeliha Emrence Hulya Azakli Duran Ustek Ilknur Tugal-Tutkun Gulsen Akman-Demir Wei Chen Christopher I Amos Michael B Dizon Afet Akdag Kose Gulsevim Azizlerli Burak Erer Oliver J Brand Virginia G Kaklamani Phaedon Kaklamanis Eldad Ben-Chetrit Miles Stanford Farida Fortune Marwen Ghabra William E R Ollier Young-Hun Cho Dongsik Bang John O'Shea Graham R Wallace Massimo Gadina Daniel L Kastner Ahmet Gül

Nat Genet 2010 Aug 11;42(8):698-702. Epub 2010 Jul 11.

National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, USA.

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August 2010

Follow-up of potential novel Graves' disease susceptibility loci, identified in the UK WTCCC genome-wide nonsynonymous SNP study.

Authors:
Paul R Newby Oliver J Pickles Samaresh Mazumdar Oliver J Brand Jaqueline D Carr-Smith Simon H S Pearce Jayne A Franklyn David M Evans Matthew J Simmonds Stephen C L Gough

Eur J Hum Genet 2010 Sep 5;18(9):1021-6. Epub 2010 May 5.

Centre for Endocrinology, Diabetes and Metabolism, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, Institute of Biomedical Research, University of Birmingham, Birmingham, West Midlands, UK.

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September 2010

Association of caveolin-1 gene polymorphism with kidney transplant fibrosis and allograft failure.

Authors:
Jason Moore Amy Jayne McKnight Matthew J Simmonds Aisling E Courtney Rajesh Hanvesakul Oliver J Brand David Briggs Simon Ball Paul Cockwell Christopher C Patterson Alexander P Maxwell Stephen C L Gough Richard Borrows

JAMA 2010 Apr;303(13):1282-7

Department of Nephrology and Transplantation, Renal Institute of Birmingham, University Hospital Birmingham, Birmingham B15 2TH, England.

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April 2010

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Authors:
Nick Craddock Matthew E Hurles Niall Cardin Richard D Pearson Vincent Plagnol Samuel Robson Damjan Vukcevic Chris Barnes Donald F Conrad Eleni Giannoulatou Chris Holmes Jonathan L Marchini Kathy Stirrups Martin D Tobin Louise V Wain Chris Yau Jan Aerts Tariq Ahmad T Daniel Andrews Hazel Arbury Anthony Attwood Adam Auton Stephen G Ball Anthony J Balmforth Jeffrey C Barrett Inês Barroso Anne Barton Amanda J Bennett Sanjeev Bhaskar Katarzyna Blaszczyk John Bowes Oliver J Brand Peter S Braund Francesca Bredin Gerome Breen Morris J Brown Ian N Bruce Jaswinder Bull Oliver S Burren John Burton Jake Byrnes Sian Caesar Chris M Clee Alison J Coffey John M C Connell Jason D Cooper Anna F Dominiczak Kate Downes Hazel E Drummond Darshna Dudakia Andrew Dunham Bernadette Ebbs Diana Eccles Sarah Edkins Cathryn Edwards Anna Elliot Paul Emery David M Evans Gareth Evans Steve Eyre Anne Farmer I Nicol Ferrier Lars Feuk Tomas Fitzgerald Edward Flynn Alistair Forbes Liz Forty Jayne A Franklyn Rachel M Freathy Polly Gibbs Paul Gilbert Omer Gokumen Katherine Gordon-Smith Emma Gray Elaine Green Chris J Groves Detelina Grozeva Rhian Gwilliam Anita Hall Naomi Hammond Matt Hardy Pile Harrison Neelam Hassanali Husam Hebaishi Sarah Hines Anne Hinks Graham A Hitman Lynne Hocking Eleanor Howard Philip Howard Joanna M M Howson Debbie Hughes Sarah Hunt John D Isaacs Mahim Jain Derek P Jewell Toby Johnson Jennifer D Jolley Ian R Jones Lisa A Jones George Kirov Cordelia F Langford Hana Lango-Allen G Mark Lathrop James Lee Kate L Lee Charlie Lees Kevin Lewis Cecilia M Lindgren Meeta Maisuria-Armer Julian Maller John Mansfield Paul Martin Dunecan C O Massey Wendy L McArdle Peter McGuffin Kirsten E McLay Alex Mentzer Michael L Mimmack Ann E Morgan Andrew P Morris Craig Mowat Simon Myers William Newman Elaine R Nimmo Michael C O'Donovan Abiodun Onipinla Ifejinelo Onyiah Nigel R Ovington Michael J Owen Kimmo Palin Kirstie Parnell David Pernet John R B Perry Anne Phillips Dalila Pinto Natalie J Prescott Inga Prokopenko Michael A Quail Suzanne Rafelt Nigel W Rayner Richard Redon David M Reid Renwick Susan M Ring Neil Robertson Ellie Russell David St Clair Jennifer G Sambrook Jeremy D Sanderson Helen Schuilenburg Carol E Scott Richard Scott Sheila Seal Sue Shaw-Hawkins Beverley M Shields Matthew J Simmonds Debbie J Smyth Elilan Somaskantharajah Katarina Spanova Sophia Steer Jonathan Stephens Helen E Stevens Millicent A Stone Zhan Su Deborah P M Symmons John R Thompson Wendy Thomson Mary E Travers Clare Turnbull Armand Valsesia Mark Walker Neil M Walker Chris Wallace Margaret Warren-Perry Nicholas A Watkins John Webster Michael N Weedon Anthony G Wilson Matthew Woodburn B Paul Wordsworth Allan H Young Eleftheria Zeggini Nigel P Carter Timothy M Frayling Charles Lee Gil McVean Patricia B Munroe Aarno Palotie Stephen J Sawcer Stephen W Scherer David P Strachan Chris Tyler-Smith Matthew A Brown Paul R Burton Mark J Caulfield Alastair Compston Martin Farrall Stephen C L Gough Alistair S Hall Andrew T Hattersley Adrian V S Hill Christopher G Mathew Marcus Pembrey Jack Satsangi Michael R Stratton Jane Worthington Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem Ouwehand Miles Parkes Nazneen Rahman John A Todd Nilesh J Samani Peter Donnelly

Nature 2010 Apr;464(7289):713-20

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April 2010

Confirmation of association of chromosome 5q31-33 with United Kingdom Caucasian Graves' disease.

Authors:
Matthew J Simmonds Kadija Yesmin Paul R Newby Oliver J Brand Jayne A Franklyn Stephen C L Gough

Thyroid 2010 Apr;20(4):413-7

Institute of Biomedical Research, University of Birmingham , Edgbaston, Birmingham, UK .

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April 2010

Association of FcGRIIa with Graves' disease: a potential role for dysregulated autoantibody clearance in disease onset/progression.

Authors:
Kadija Yesmin Chantal Hargreaves Paul R Newby Oliver J Brand Joanne M Heward Jayne A Franklyn Stephen C L Gough Matthew J Simmonds

Clin Endocrinol (Oxf) 2010 Jul 10;73(1):119-25. Epub 2010 Feb 10.

Centre for Endocrinology, Diabetes and Metabolism, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, Institute of Biomedical Research, University of Birmingham, Edgbaston, Birmingham, UK.

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July 2010

Association of the thyroid stimulating hormone receptor gene (TSHR) with Graves' disease.

Authors:
Oliver J Brand Jeffrey C Barrett Matthew J Simmonds Paul R Newby Christopher J McCabe Christopher K Bruce Boris Kysela Jackie D Carr-Smith Thomas Brix Penny J Hunt Wilmar M Wiersinga Laszlo Hegedüs John Connell John A H Wass Jayne A Franklyn Anthony P Weetman Joanne M Heward Stephen C L Gough

Hum Mol Genet 2009 May 25;18(9):1704-13. Epub 2009 Feb 25.

Institute of Biomedical Research, University of Birmingham, Edgbaston, West Midlands, UK.

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May 2009

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Authors:
Paul R Burton David G Clayton Lon R Cardon Nick Craddock Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem H Ouwehand Nilesh J Samani John A Todd Peter Donnelly Jeffrey C Barrett Dan Davison Doug Easton David M Evans Hin-Tak Leung Jonathan L Marchini Andrew P Morris Chris C A Spencer Martin D Tobin Antony P Attwood James P Boorman Barbara Cant Ursula Everson Judith M Hussey Jennifer D Jolley Alexandra S Knight Kerstin Koch Elizabeth Meech Sarah Nutland Christopher V Prowse Helen E Stevens Niall C Taylor Graham R Walters Neil M Walker Nicholas A Watkins Thilo Winzer Richard W Jones Wendy L McArdle Susan M Ring David P Strachan Marcus Pembrey Gerome Breen David St Clair Sian Caesar Katharine Gordon-Smith Lisa Jones Christine Fraser Elaine K Green Detelina Grozeva Marian L Hamshere Peter A Holmans Ian R Jones George Kirov Valentina Moskivina Ivan Nikolov Michael C O'Donovan Michael J Owen David A Collier Amanda Elkin Anne Farmer Richard Williamson Peter McGuffin Allan H Young I Nicol Ferrier Stephen G Ball Anthony J Balmforth Jennifer H Barrett Timothy D Bishop Mark M Iles Azhar Maqbool Nadira Yuldasheva Alistair S Hall Peter S Braund Richard J Dixon Massimo Mangino Suzanne Stevens John R Thompson Francesca Bredin Mark Tremelling Miles Parkes Hazel Drummond Charles W Lees Elaine R Nimmo Jack Satsangi Sheila A Fisher Alastair Forbes Cathryn M Lewis Clive M Onnie Natalie J Prescott Jeremy Sanderson Christopher G Matthew Jamie Barbour M Khalid Mohiuddin Catherine E Todhunter John C Mansfield Tariq Ahmad Fraser R Cummings Derek P Jewell John Webster Morris J Brown Mark G Lathrop John Connell Anna Dominiczak Carolina A Braga Marcano Beverley Burke Richard Dobson Johannie Gungadoo Kate L Lee Patricia B Munroe Stephen J Newhouse Abiodun Onipinla Chris Wallace Mingzhan Xue Mark Caulfield Martin Farrall Anne Barton Ian N Bruce Hannah Donovan Steve Eyre Paul D Gilbert Samantha L Hilder Anne M Hinks Sally L John Catherine Potter Alan J Silman Deborah P M Symmons Wendy Thomson Jane Worthington David B Dunger Barry Widmer Timothy M Frayling Rachel M Freathy Hana Lango John R B Perry Beverley M Shields Michael N Weedon Andrew T Hattersley Graham A Hitman Mark Walker Kate S Elliott Christopher J Groves Cecilia M Lindgren Nigel W Rayner Nicolas J Timpson Eleftheria Zeggini Melanie Newport Giorgio Sirugo Emily Lyons Fredrik Vannberg Adrian V S Hill Linda A Bradbury Claire Farrar Jennifer J Pointon Paul Wordsworth Matthew A Brown Jayne A Franklyn Joanne M Heward Matthew J Simmonds Stephen C L Gough Sheila Seal Michael R Stratton Nazneen Rahman Maria Ban An Goris Stephen J Sawcer Alastair Compston David Conway Muminatou Jallow Melanie Newport Giorgio Sirugo Kirk A Rockett Suzannah J Bumpstead Amy Chaney Kate Downes Mohammed J R Ghori Rhian Gwilliam Sarah E Hunt Michael Inouye Andrew Keniry Emma King Ralph McGinnis Simon Potter Rathi Ravindrarajah Pamela Whittaker Claire Widden David Withers Niall J Cardin Dan Davison Teresa Ferreira Joanne Pereira-Gale Ingeleif B Hallgrimsdo'ttir Bryan N Howie Zhan Su Yik Ying Teo Damjan Vukcevic David Bentley Matthew A Brown Alastair Compston Martin Farrall Alistair S Hall Andrew T Hattersley Adrian V S Hill Miles Parkes Marcus Pembrey Michael R Stratton Sarah L Mitchell Paul R Newby Oliver J Brand Jackie Carr-Smith Simon H S Pearce R McGinnis A Keniry P Deloukas John D Reveille Xiaodong Zhou Anne-Marie Sims Alison Dowling Jacqueline Taylor Tracy Doan John C Davis Laurie Savage Michael M Ward Thomas L Learch Michael H Weisman Mathew Brown

Nat Genet 2007 Nov 21;39(11):1329-37. Epub 2007 Oct 21.

Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.

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November 2007

Association of the interleukin-2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs.

Authors:
Oliver J Brand Christopher E Lowe Joanne M Heward Jayne A Franklyn Jason D Cooper John A Todd Stephen C L Gough

Clin Endocrinol (Oxf) 2007 Apr;66(4):508-12

Department of Medicine, Division of Medical Sciences, Institute of Biomedical Research, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.

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April 2007

Association of PTPN22 haplotypes with Graves' disease.

Authors:
Joanne M Heward Oliver J Brand Jeffrey C Barrett Jackie D Carr-Smith Jayne A Franklyn Stephen C Gough

J Clin Endocrinol Metab 2007 Feb 5;92(2):685-90. Epub 2006 Dec 5.

Department of Medicine, Division of Medical Sciences, Institute of Biomedical Research, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.

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February 2007