Publications by authors named "Oliver Fiehn"

100Publications

Pharmacophore hybridisation and nanoscale assembly to discover self-delivering lysosomotropic new-chemical entities for cancer therapy.

Nat Commun 2020 09 15;11(1):4615. Epub 2020 Sep 15.

Department of Biochemistry and Molecular Medicine, UC Davis Comprehensive Cancer Center, University of California Davis, Sacramento, CA, 95817, USA.

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http://dx.doi.org/10.1038/s41467-020-18399-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493904PMC
September 2020

Cadmium-mediated lung injury is exacerbated by the persistence of classically activated macrophages.

J Biol Chem 2020 Sep 11. Epub 2020 Sep 11.

Medicine, University of Alabama at Birmingham, United States.

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http://dx.doi.org/10.1074/jbc.RA120.013632DOI Listing
September 2020

Metabolomics-related nutrient patterns at seroconversion and risk of progression to type 1 diabetes.

Pediatr Diabetes 2020 Jul 20. Epub 2020 Jul 20.

Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

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http://dx.doi.org/10.1111/pedi.13085DOI Listing
July 2020

A lipidome-wide association study of the lipoprotein insulin resistance index.

Lipids Health Dis 2020 Jun 25;19(1):153. Epub 2020 Jun 25.

Department of Epidemiology, University of Alabama at Birmingham, 1665 University Blvd, Birmingham, AL, 35294, USA.

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http://dx.doi.org/10.1186/s12944-020-01321-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318473PMC
June 2020

l-Arginine supplementation in severe asthma.

JCI Insight 2020 Jul 9;5(13). Epub 2020 Jul 9.

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, UCD, Sacramento, California, USA.

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http://dx.doi.org/10.1172/jci.insight.137777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406254PMC
July 2020

Retip: Retention Time Prediction for Compound Annotation in Untargeted Metabolomics.

Anal Chem 2020 06 21;92(11):7515-7522. Epub 2020 May 21.

West Coast Metabolomics Center, UC Davis Genome Center, University of California, Davis, 451 Health Sciences Drive, Davis, California 95616, United States.

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http://dx.doi.org/10.1021/acs.analchem.9b05765DOI Listing
June 2020

Serum triglycerides in Alzheimer disease: Relation to neuroimaging and CSF biomarkers.

Neurology 2020 05 1;94(20):e2088-e2098. Epub 2020 May 1.

From the Department of Radiology and Imaging Sciences (M.M.B., K.N., S.L.R., T.J., A.J.S.), Center for Neuroimaging, Indiana Alzheimer Disease Center (M.M.B., K.N., S.L.R., T.J., A.J.S.), Medical and Molecular Genetics Department (M.M.B., T.J., A.J.S.), and Medical Scientist Training Program (M.M.B.), Indiana University School of Medicine, Indianapolis; Department of Pediatrics (S.B.), University of Arkansas for Medical Sciences, Little Rock; Department of Environmental Medicine and Public Health (D.K.B.), Icahn School of Medicine at Mt Sinai, New York; NIH-West Coast Metabolomics Center (D.K.B., O.F.), University of California, Davis; Rosa & Co LLC (R.B.), San Carlos, CA; Institute of Bioinformatics and Systems Biology (M.A.), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Pathology & Laboratory Medicine (J.Q.T., L.M.S.), University of Pennsylvania, Philadelphia; Department of Radiology (M.W.W.), Center for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center/University of California San Francisco; and Department of Psychiatry and Behavioral Sciences (M.A., P.M.D., R.K.-D.), Duke Institute of Brain Sciences (R.K.-D.), and Department of Medicine (R.K.-D.), Duke University, Durham, NC.

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http://dx.doi.org/10.1212/WNL.0000000000009436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526673PMC
May 2020

Thioproline formation as a driver of formaldehyde toxicity in Escherichia coli.

Biochem J 2020 May;477(9):1745-1757

Department of Horticultural Sciences, University of Florida, Gainesville, FL, U.S.A.

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http://dx.doi.org/10.1042/BCJ20200198DOI Listing
May 2020

The foxtail millet (Setaria italica) terpene synthase gene family.

Plant J 2020 07 3;103(2):781-800. Epub 2020 May 3.

Department of Plant Biology, University of California-Davis, One Shields Avenue, Davis, 95616, CA, USA.

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http://dx.doi.org/10.1111/tpj.14771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497057PMC
July 2020

In-Silico-Generated Library for Sensitive Detection of 2-Dimethylaminoethylamine Derivatized FAHFA Lipids Using High-Resolution Tandem Mass Spectrometry.

Anal Chem 2020 04 31;92(8):5960-5968. Epub 2020 Mar 31.

Department of Chemistry, Wuhan University, Wuhan 430072, PR China.

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http://dx.doi.org/10.1021/acs.analchem.0c00172DOI Listing
April 2020

A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors.

Cell 2020 03;180(5):862-877.e22

Department of Cardiovascular & Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44106, USA; Center for Microbiome & Human Health, Cleveland Clinic, Cleveland, OH 44106, USA; Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH 44106, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402401PMC
March 2020

Abrogation of esophageal carcinoma development in miR-31 knockout rats.

Proc Natl Acad Sci U S A 2020 03 2;117(11):6075-6085. Epub 2020 Mar 2.

Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210;

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http://dx.doi.org/10.1073/pnas.1920333117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084137PMC
March 2020

Adipocyte-Induced FABP4 Expression in Ovarian Cancer Cells Promotes Metastasis and Mediates Carboplatin Resistance.

Cancer Res 2020 04 13;80(8):1748-1761. Epub 2020 Feb 13.

Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-1999DOI Listing
April 2020

Metabolic Control over mTOR-Dependent Diapause-like State.

Dev Cell 2020 Jan;52(2):236-250.e7

Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98109, USA; Department of Bioengineering, University of Washington, Seattle, WA 98195, USA; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2019.12.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204393PMC
January 2020

Erratum: Ismail, I.T.; et al. Inborn Errors of Metabolism in the Era of Untargeted Metabolomics and Lipidomics. 2019, , 242.

Metabolites 2020 Jan 6;10(1). Epub 2020 Jan 6.

NIH West Coast Metabolomics Center, University of California Davis, Davis, CA 95616, USA.

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http://dx.doi.org/10.3390/metabo10010025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022264PMC
January 2020

Gestational Hypoxia and Programing of Lung Metabolism.

Front Physiol 2019 29;10:1453. Epub 2019 Nov 29.

Lawrence D. Longo MD Center for Perinatal Biology, School of Medicine, Loma Linda University, Loma Linda, CA, United States.

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http://dx.doi.org/10.3389/fphys.2019.01453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895135PMC
November 2019

Interaction of Gut Microbiota and High-Sodium, Low-Potassium Diet in Altering Plasma Triglyceride Profiles Revealed by Lipidomics Analysis.

Mol Nutr Food Res 2019 12 28;63(24):e1900752. Epub 2019 Nov 28.

Department of Physiology and Neuroscience, Keck School of Medicine of USC, Los Angeles, CA, 90089, USA.

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http://dx.doi.org/10.1002/mnfr.201900752DOI Listing
December 2019

Inborn Errors of Metabolism in the Era of Untargeted Metabolomics and Lipidomics.

Metabolites 2019 Oct 21;9(10). Epub 2019 Oct 21.

NIH West Coast Metabolomics Center, University of California Davis, Davis, CA 95616, USA.

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http://dx.doi.org/10.3390/metabo9100242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835511PMC
October 2019

Mevalonate Pathway Promiscuity Enables Noncanonical Terpene Production.

ACS Synth Biol 2019 10 2;8(10):2238-2247. Epub 2019 Oct 2.

Department of Energy Joint BioEnergy Institute , 5885 Hollis Street , Emeryville , California 94608 , United States.

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http://dx.doi.org/10.1021/acssynbio.9b00230DOI Listing
October 2019

Serum and urinary metabolomics and outcomes in cirrhosis.

PLoS One 2019 27;14(9):e0223061. Epub 2019 Sep 27.

West Coast Metabolomics Center, University of California, Davis, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0223061PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764675PMC
April 2020

Generating the Blood Exposome Database Using a Comprehensive Text Mining and Database Fusion Approach.

Environ Health Perspect 2019 09 26;127(9):97008. Epub 2019 Sep 26.

National Institutes of Health (NIH) West Coast Metabolomics Center, Genome Center, University of California, Davis, Davis, California, USA.

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http://dx.doi.org/10.1289/EHP4713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794490PMC
September 2019

Sets of coregulated serum lipids are associated with Alzheimer's disease pathophysiology.

Alzheimers Dement (Amst) 2019 Dec 5;11:619-627. Epub 2019 Sep 5.

Department of Psychiatry and Behavioral Sciences, Department of Medicine and the Duke Institute for Brain Sciences, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1016/j.dadm.2019.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732667PMC
December 2019

Rethinking the PDH Bypass and GABA Shunt as Thiamin-Deficiency Workarounds.

Plant Physiol 2019 10 13;181(2):389-393. Epub 2019 Aug 13.

Horticultural Sciences Department, University of Florida, Gainesville, Florida 32611

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http://dx.doi.org/10.1104/pp.19.00857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776870PMC
October 2019

Laboratory Screening Protocol to Identify Novel Oleaginous Yeasts.

Methods Mol Biol 2019 ;1995:33-50

Phaff Yeast Culture Collection, Department of Food Science and Technology, University of California, Davis, Davis, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-9484-7_2DOI Listing
February 2020

Alternative outlets for sustaining photosynthetic electron transport during dark-to-light transitions.

Proc Natl Acad Sci U S A 2019 06 17;116(23):11518-11527. Epub 2019 May 17.

Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1903185116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561286PMC
June 2019

Chronic, Intermittent Microdoses of the Psychedelic ,-Dimethyltryptamine (DMT) Produce Positive Effects on Mood and Anxiety in Rodents.

ACS Chem Neurosci 2019 07 4;10(7):3261-3270. Epub 2019 Mar 4.

Department of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.

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http://dx.doi.org/10.1021/acschemneuro.8b00692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639775PMC
July 2019

Systematic Error Removal Using Random Forest for Normalizing Large-Scale Untargeted Lipidomics Data.

Anal Chem 2019 03 19;91(5):3590-3596. Epub 2019 Feb 19.

West Coast Metabolomics Center, UC Davis Genome Center , University of California, Davis , 451 Health Sciences Drive , Davis , California 95616 , United States.

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http://dx.doi.org/10.1021/acs.analchem.8b05592DOI Listing
March 2019

The metabolite repair enzyme Nit1 is a dual-targeted amidase that disposes of damaged glutathione in .

Biochem J 2019 02 19;476(4):683-697. Epub 2019 Feb 19.

Department of Horticultural Sciences, University of Florida, Gainesville, FL, U.S.A.

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http://dx.doi.org/10.1042/BCJ20180931DOI Listing
February 2019

Rapid LC-MS/MS quantification of cancer related acetylated polyamines in human biofluids.

Talanta 2019 May 26;196:415-419. Epub 2018 Dec 26.

University of California, One Shields Avenue, Davis, CA 95616, USA. Electronic address:

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http://dx.doi.org/10.1016/j.talanta.2018.12.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050201PMC
May 2019

Structure Annotation of All Mass Spectra in Untargeted Metabolomics.

Anal Chem 2019 02 16;91(3):2155-2162. Epub 2019 Jan 16.

West Coast Metabolomics Center , University of California, Davis , Davis , California 95616 , United States.

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http://pubs.acs.org/doi/10.1021/acs.analchem.8b04698
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http://dx.doi.org/10.1021/acs.analchem.8b04698DOI Listing
February 2019

Effects of Gut Bacteria Depletion and High-Na and Low-K Intake on Circulating Levels of Biogenic Amines.

Mol Nutr Food Res 2019 02 12;63(4):e1801184. Epub 2018 Dec 12.

Department of Physiology and Neuroscience, Keck School of Medicine of USC, Los Angeles, CA 90089, USA.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/mnfr.2018011
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http://dx.doi.org/10.1002/mnfr.201801184DOI Listing
February 2019

Generation and quality control of lipidomics data for the alzheimer's disease neuroimaging initiative cohort.

Sci Data 2018 11 20;5:180263. Epub 2018 Nov 20.

NIH-West Coast Metabolomics Center, University of California, Davis, 451 Health Sciences Drive, Davis, California 95616, United States.

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http://dx.doi.org/10.1038/sdata.2018.263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244184PMC
November 2018

Effects of Centella asiatica extract on antioxidant status and liver metabolome of rotenone-treated rats using GC-MS.

Biomed Chromatogr 2019 Feb 17;33(2):e4395. Epub 2018 Oct 17.

Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.

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http://dx.doi.org/10.1002/bmc.4395DOI Listing
February 2019

NAD(P)HX repair deficiency causes central metabolic perturbations in yeast and human cells.

FEBS J 2018 09 27;285(18):3376-3401. Epub 2018 Aug 27.

Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg.

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http://dx.doi.org/10.1111/febs.14631DOI Listing
September 2018

Increasing Compound Identification Rates in Untargeted Lipidomics Research with Liquid Chromatography Drift Time-Ion Mobility Mass Spectrometry.

Anal Chem 2018 09 29;90(18):10758-10764. Epub 2018 Aug 29.

West Coast Metabolomics Center , UC Davis , Davis , California 95616 , United States.

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http://dx.doi.org/10.1021/acs.analchem.8b01527DOI Listing
September 2018

Sex-associated differences in baseline urinary metabolites of healthy adults.

Sci Rep 2018 08 8;8(1):11883. Epub 2018 Aug 8.

Departments of Surgery and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

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http://dx.doi.org/10.1038/s41598-018-29592-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082868PMC
August 2018

Salvage of the 5-deoxyribose byproduct of radical SAM enzymes.

Nat Commun 2018 08 6;9(1):3105. Epub 2018 Aug 6.

Horticultural Sciences Department, University of Florida, Gainesville, FL, 32611, USA.

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http://dx.doi.org/10.1038/s41467-018-05589-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079011PMC
August 2018

Gut microbial and metabolomic profiles after fecal microbiota transplantation in pediatric ulcerative colitis patients.

FEMS Microbiol Ecol 2018 09;94(9)

Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, USA 3315 McGaugh Hall, Irvine, CA, USA 92697.

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http://dx.doi.org/10.1093/femsec/fiy133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454419PMC
September 2018

Reference samples guide variable selection for correlation of wine sensory and volatile profiling data.

Food Chem 2018 Nov 12;267:344-354. Epub 2017 Oct 12.

Department of Viticulture and Enology, University of California, Davis, CA 95616, USA. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2017.10.073DOI Listing
November 2018

Software Tools and Approaches for Compound Identification of LC-MS/MS Data in Metabolomics.

Metabolites 2018 May 10;8(2). Epub 2018 May 10.

NIH West Coast Metabolomics Center, UC Davis Genome Center, University of California, Davis, CA 95616, USA.

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http://dx.doi.org/10.3390/metabo8020031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027441PMC
May 2018

Tracking Polymicrobial Metabolism in Cystic Fibrosis Airways: Metabolism and Physiology Are Influenced by -Derived Metabolites.

mSphere 2018 04 25;3(2). Epub 2018 Apr 25.

Department of Molecular Biology and Biochemistry, University of California, Irvine, California, USA

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http://dx.doi.org/10.1128/mSphere.00151-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917424PMC
April 2018

Diversity of Neuropeptide Cell-Cell Signaling Molecules Generated by Proteolytic Processing Revealed by Neuropeptidomics Mass Spectrometry.

J Am Soc Mass Spectrom 2018 05 17;29(5):807-816. Epub 2018 Apr 17.

West Coast Metabolomics Center, UC Davis Genome Center, University of California Davis, Davis, CA, 95616, USA.

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http://dx.doi.org/10.1007/s13361-018-1914-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946320PMC
May 2018

Integrating bioinformatics approaches for a comprehensive interpretation of metabolomics datasets.

Curr Opin Biotechnol 2018 12 6;54:1-9. Epub 2018 Feb 6.

NIH West Coast Metabolomics Center, University of California Davis, Davis, CA 95616, United States; Biochemistry Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09581669173025
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http://dx.doi.org/10.1016/j.copbio.2018.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358024PMC
December 2018

Obesogenic diets alter metabolism in mice.

PLoS One 2018 11;13(1):e0190632. Epub 2018 Jan 11.

NIH West Coast Metabolomics Center, University of California Davis, Davis, CA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190632PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764261PMC
February 2018

Strategies for dereplication of natural compounds using high-resolution tandem mass spectrometry.

Phytochem Lett 2017 Sep 17;21:313-319. Epub 2016 Nov 17.

West Coast Metabolomics Center, UC Davis, Davis 95616, California, U.S.A.

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http://dx.doi.org/10.1016/j.phytol.2016.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720153PMC
September 2017

Chemical Similarity Enrichment Analysis (ChemRICH) as alternative to biochemical pathway mapping for metabolomic datasets.

Sci Rep 2017 11 6;7(1):14567. Epub 2017 Nov 6.

NIH-West Coast Metabolomics Center, Genome Center University of California, Davis, USA.

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http://dx.doi.org/10.1038/s41598-017-15231-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673929PMC
November 2017

Validating Quantitative Untargeted Lipidomics Across Nine Liquid Chromatography-High-Resolution Mass Spectrometry Platforms.

Anal Chem 2017 11 7;89(22):12360-12368. Epub 2017 Nov 7.

West Coast Metabolomics Center, UC Davis Genome Center, University of California, Davis , Davis, California 95616, United States.

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http://dx.doi.org/10.1021/acs.analchem.7b03404DOI Listing
November 2017

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma.

J Lipid Res 2017 12 6;58(12):2275-2288. Epub 2017 Oct 6.

Lipidomics Core Facility and Department of Pathology, Wayne State University, Detroit, MI.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M079012
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http://dx.doi.org/10.1194/jlr.M079012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711491PMC
December 2017