Publications by authors named "Oliver Distler"

100Publications

Mechanisms of progressive fibrosis in connective tissue disease (CTD)-associated interstitial lung diseases (ILDs).

Ann Rheum Dis 2020 Oct 9. Epub 2020 Oct 9.

Division of Rheumatology and Department of Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/annrheumdis-2020-217230DOI Listing
October 2020

Fibroblast growth factor receptor 3 activates a network of profibrotic signaling pathways to promote fibrosis in systemic sclerosis.

Sci Transl Med 2020 Sep;12(563)

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scitranslmed.aaz5506DOI Listing
September 2020

Intravenous versus oral cyclophosphamide for lung and/or skin fibrosis in systemic sclerosis: an indirect comparison from EUSTAR and randomised controlled trials.

Clin Exp Rheumatol 2020 May-Jun;38 Suppl 125(3):161-168. Epub 2020 Aug 27.

Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Firenze, Italy, and Department of Medicine, Division of Rheumatology, University of California Los Angeles, CA, USA.

View Article

Download full-text PDF

Source
September 2020

Visual assessment of digital ulcers in systemic sclerosis analysed by eye tracking: implications for wound assessment.

Clin Exp Rheumatol 2020 May-Jun;38 Suppl 125(3):137-139. Epub 2020 Aug 27.

Department of Rheumatology, University Hospital Zurich, Switzerland.

View Article

Download full-text PDF

Source
September 2020

Impaired micronutrients and prealbumin in patients with established and very early systemic sclerosis.

Clin Exp Rheumatol 2020 May-Jun;38 Suppl 125(3):120-126. Epub 2020 Jul 29.

Department of Rheumatology, University Hospital Zurich, Switzerland.

View Article

Download full-text PDF

Source
September 2020

The need for a holistic approach for SSc-ILD - achievements and ambiguity in a devastating disease.

Respir Res 2020 Jul 23;21(1):197. Epub 2020 Jul 23.

Center for Interstitial and Rare Lung Diseases, Pneumology, Thoraxklinik, Heidelberg University Hospital and German Center for Lung Research, Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12931-020-01459-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379834PMC
July 2020

Response to: 'Riociguat in systemic sclerosis: a potential for disease modification' by Jain and Dhir.

Ann Rheum Dis 2020 Jul 15. Epub 2020 Jul 15.

Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/annrheumdis-2020-218194DOI Listing
July 2020

The AP1 Transcription Factor Fosl2 Promotes Systemic Autoimmunity and Inflammation by Repressing Treg Development.

Cell Rep 2020 Jun;31(13):107826

Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland; Faculty of Medicine, University of Zurich, Zurich, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2020.107826DOI Listing
June 2020

On the Reliability of Suction Measurements for Skin Characterization.

J Biomech Eng 2020 Jun 30. Epub 2020 Jun 30.

ETH Zurich, Institute for Mechanical Systems, Leonhardstrasse 21, 8092 Zürich, Switzerland; Empa, Swiss Federal Laboratories for Materials Science and Technology, 8600 Dübendorf, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4047661DOI Listing
June 2020

Validation of the suction device Nimble for the assessment of skin fibrosis in systemic sclerosis.

Arthritis Res Ther 2020 06 3;22(1):128. Epub 2020 Jun 3.

Department of Rheumatology, University Hospital Zurich, Gloriastrasse 25, 8091, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13075-020-02214-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268280PMC
June 2020

Pulmonary Hypertension in Adults with Congenital Heart Disease: Real-World Data from the International COMPERA-CHD Registry.

J Clin Med 2020 05 13;9(5). Epub 2020 May 13.

Universitätsklinik Köln- Herzzentrum, Klinik III für Innere Medizin, 50937 Köln, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jcm9051456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290703PMC
May 2020

Evaluation of botulinum toxin A injections for the treatment of refractory chronic digital ulcers in patients with systemic sclerosis.

Clin Exp Rheumatol 2020 May-Jun;38 Suppl 125(3):154-160. Epub 2020 Apr 15.

Centre of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Switzerland.

View Article

Download full-text PDF

Source
September 2020

COVID-19 in a patient with systemic sclerosis treated with tocilizumab for SSc-ILD.

Ann Rheum Dis 2020 05 2;79(5):668-669. Epub 2020 Apr 2.

Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/annrheumdis-2020-217442DOI Listing
May 2020

[Primary Sjögren's Syndrome - News on Diagnostics and Therapy].

Praxis (Bern 1994) 2020 ;109(5):333-339

Klinik für Rheumatologie, Universitätsspital Zürich.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1024/1661-8157/a003442DOI Listing
July 2020

[Systemic Autoimmune Diseases - Challenges for the Daily Practice].

Praxis (Bern 1994) 2020;109(5):323

Klinik für Rheumatologie, Universitätsspital Zürich.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1024/1661-8157/a003440DOI Listing
July 2020

Significant weight loss in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database.

Ann Rheum Dis 2020 08 25;79(8):1123-1125. Epub 2020 Mar 25.

Division of Rheumatology, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/annrheumdis-2020-217035DOI Listing
August 2020

The Challenge of Very Early Systemic Sclerosis: A Combination of Mild and Early Disease?

J Rheumatol 2020 Mar 15. Epub 2020 Mar 15.

E. Blaja, MD, S. Jordan, PhD, C.M. Mihai, MD, PhD, R. Dobrota, MD, PhD, M.O. Becker, MD, B. Maurer, MD, O. Distler, Professor of Rheumatology, MD, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland; M. Matucci-Cerinic, Division of Rheumatology, University of Florence, Florence, Italy. B. Maurer had grant/research support from AbbVie, Protagen, Novartis; congress support from Pfizer, Roche, Actelion, and MSD; and a consultancy relationship with Novartis. In addition, BM has a patent mir-29 for the treatment of systemic sclerosis (SSc) registered. The work of BM is supported by the Prof. Max Cloetta Foundation. O. Distler had a consultancy relationship and/or has received research funding from Actelion, Acceleron Pharma, Amgen, AnaMar, Baecon Discovery, Blade Therapeutics, Bayer, Boehringer Ingelheim, Catenion, CSL Behring, Curzion Pharmaceuticals, Ergonex, Glenmark Pharmaceuticals GSK, Inventiva, Italfarmaco, iQvia, Lilly, medac, Medscape, Mitsubishi Tanabe Pharma, MSD, Novartis, Pfizer, Roche, Target Bio Science, and UCB in the area of potential treatments of scleroderma and its complications. In addition, Prof. Distler has a patent mir-29 for the treatment of SSc issued (US8247389, EP2331143). Address correspondence to Dr. O. Distler, University Hospital Zurich, Department of Rheumatology, Gloriastr. 25, CH-8091 Zurich, Switzerland. Email: Accepted for publication March 6, 2020.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3899/jrheum.190976DOI Listing
March 2020

Safety and effectiveness of abatacept in systemic sclerosis: The EUSTAR experience.

Semin Arthritis Rheum 2020 Feb 3. Epub 2020 Feb 3.

Paris Descartes University, INSERM U1016, Sorbone Paris Cité, Rheumatology A Department, Cochin Hospital, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semarthrit.2019.12.004DOI Listing
February 2020

TGF-β-induced epigenetic deregulation of SOCS3 facilitates STAT3 signaling to promote fibrosis.

J Clin Invest 2020 May;130(5):2347-2363

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI122462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190914PMC
May 2020

Nintedanib for Systemic Sclerosis-Associated Interstitial Lung Disease. Reply.

N Engl J Med 2019 10;381(16):1596-1597

Imperial College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMc1910735DOI Listing
October 2019

Does angiotensin and endothelin receptor blockade have an impact on lung function? An analysis from the EUSTAR database.

Clin Exp Rheumatol 2019 Jul-Aug;37 Suppl 119(4):154-155. Epub 2019 Sep 26.

University Hospital Charité, Rheumatology and Clinical Immunology, Berlin, and University Hospital Schleswig-Holstein, Rheumatology, Lübeck, Germany.

View Article

Download full-text PDF

Source
October 2019

Current and future perspectives on management of systemic sclerosis-associated interstitial lung disease.

Expert Rev Clin Immunol 2019 10 30;15(10):1009-1017. Epub 2019 Sep 30.

National Institute for Health Research Respiratory Clinical Research Facility, Royal Brompton and Harefield NHS Foundation Trust, and Fibrosis Research Group, National Heart and Lung Institute, Imperial College , London , UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/1744666X.2020.1668269DOI Listing
October 2019

Fast track algorithm: How to differentiate a "scleroderma pattern" from a "non-scleroderma pattern".

Autoimmun Rev 2019 Nov 11;18(11):102394. Epub 2019 Sep 11.

Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genoa, IRCCS San Martino Polyclinic Hospital, Genoa, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.autrev.2019.102394DOI Listing
November 2019

Experimental Mouse Model of Bleomycin-Induced Skin Fibrosis.

Curr Protoc Immunol 2019 09;126(1):e88

Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cpim.88DOI Listing
September 2019

Might Nailfold Capillaroscopy Be a "Proxy" for Lung Involvement in Connective Tissue Diseases?

J Rheumatol 2019 09;46(9):1061-1063

Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Institute for Research and Health Care San Martino Polyclinic Hospital, University of Genoa, Genoa, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3899/jrheum.181408DOI Listing
September 2019

Identification and Isolation of Cardiac Fibroblasts From the Adult Mouse Heart Using Two-Color Flow Cytometry.

Front Cardiovasc Med 2019 1;6:105. Epub 2019 Aug 1.

Department of Rheumatology, Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fcvm.2019.00105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686717PMC
August 2019

Regulation of Fibroblast Apoptosis and Proliferation by MicroRNA-125b in Systemic Sclerosis.

Arthritis Rheumatol 2019 12 1;71(12):2068-2080. Epub 2019 Nov 1.

University Hospital Zurich, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/art.41041DOI Listing
December 2019

TET1 is an important transcriptional activator of TNFα expression in macrophages.

PLoS One 2019 19;14(6):e0218551. Epub 2019 Jun 19.

Department of Rheumatology, Center of Experimental Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218551PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583962PMC
February 2020

Nintedanib for Systemic Sclerosis-Associated Interstitial Lung Disease.

N Engl J Med 2019 06 20;380(26):2518-2528. Epub 2019 May 20.

From the Department of Rheumatology, University Hospital Zurich, Zurich (O.D.), and Boehringer Ingelheim (Schweiz), Basel (M. Gahlemann) - both in Switzerland; the Respiratory Institute, Cleveland Clinic, Cleveland (K.B.H.); the Departments of Pulmonary Medicine and Oncology (A.A.) and Allergy and Rheumatology (M.K.), Nippon Medical School Graduate School of Medicine, Tokyo; University of Colorado School of Medicine, Aurora (A.F.); the Division of Rheumatology and Clinical Immunogenetics, University of Texas McGovern Medical School, Houston (M.D.M.); University of Washington, Seattle (G.R.); Boehringer Ingelheim Pharma, Biberach an der Riss (W.S.), Boehringer Ingelheim International, Ingelheim am Rhein (M.A., E.C.-B., S.S., K.T.), and the Department of Sports Medicine, University of Tübingen, Tübingen (K.T.) - all in Germany; Boehringer Ingelheim France, Reims, France (M. Girard); and the National Heart and Lung Institute, Imperial College London, and the National Institute for Health Research Clinical Research Facility, Royal Brompton Hospital, London (T.M.M.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1903076DOI Listing
June 2019

Involvement of the myeloid cell compartment in fibrogenesis and systemic sclerosis.

Nat Rev Rheumatol 2019 05;15(5):288-302

Department of Rheumatology, Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41584-019-0212-zDOI Listing
May 2019

Response to: 'Will SPAR be useful in the usual patients with scleroderma?' by Chattopadhyay .

Ann Rheum Dis 2019 11 10;78(11):e126. Epub 2018 Nov 10.

Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/annrheumdis-2018-214270DOI Listing
November 2019

Targeted therapy of pulmonary arterial hypertension: Updated recommendations from the Cologne Consensus Conference 2018.

Int J Cardiol 2018 Dec 25;272S:37-45. Epub 2018 Aug 25.

German Centre for Lung Research (DZL), Germany; Universities of Giessen and Marburg Lung Center (UGMLC), Gießen, Germany; Department for Pneumology, Kerckhoff Hospital Bad Nauheim, Germany; Department of Medicine, Imperial College, London, UK.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01675273183434
Publisher Site
http://dx.doi.org/10.1016/j.ijcard.2018.08.082DOI Listing
December 2018

Evaluation of Tc-rhAnnexin V-128 SPECT/CT as a diagnostic tool for early stages of interstitial lung disease associated with systemic sclerosis.

Arthritis Res Ther 2018 08 16;20(1):183. Epub 2018 Aug 16.

Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Gloriastrasse 25, 8091, Zurich, Switzerland.

View Article

Download full-text PDF

Source
https://arthritis-research.biomedcentral.com/articles/10.118
Publisher Site
http://dx.doi.org/10.1186/s13075-018-1681-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097327PMC
August 2018

A novel ultra-light suction device for mechanical characterization of skin.

PLoS One 2018 8;13(8):e0201440. Epub 2018 Aug 8.

Institute for Mechanical Systems, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201440PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082559PMC
January 2019

Response to: 'Can we further SPARkle the SPAR model?' by Kavadichanda .

Ann Rheum Dis 2019 09 21;78(9):e94. Epub 2018 Jul 21.

Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/annrheumdis-2018-213962DOI Listing
September 2019

Haematopoietic stem cell transplantation in systemic sclerosis.

RMD Open 2018 17;4(1):e000533. Epub 2018 Jun 17.

Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/rmdopen-2017-000533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045702PMC
June 2018

Gouty arthritis: Can we avoid unnecessary dual-energy CT examinations using prior radiographs?

PLoS One 2018 10;13(7):e0200473. Epub 2018 Jul 10.

Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0200473PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039044PMC
January 2019