Olga Pletnikova

Olga Pletnikova

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Olga Pletnikova

Publications by authors named "Olga Pletnikova"

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A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Authors:
Sven J van der Lee Olivia J Conway Iris Jansen Minerva M Carrasquillo Luca Kleineidam Erik van den Akker Isabel Hernández Kristel R van Eijk Najada Stringa Jason A Chen Anna Zettergren Till F M Andlauer Monica Diez-Fairen Javier Simon-Sanchez Alberto Lleó Henrik Zetterberg Marianne Nygaard Cornelis Blauwendraat Jeanne E Savage Jonas Mengel-From Sonia Moreno-Grau Michael Wagner Juan Fortea Michael J Keogh Kaj Blennow Ingmar Skoog Manuel A Friese Olga Pletnikova Miren Zulaica Carmen Lage Itziar de Rojas Steffi Riedel-Heller Ignacio Illán-Gala Wei Wei Bernard Jeune Adelina Orellana Florian Then Bergh Xue Wang Marc Hulsman Nina Beker Niccolo Tesi Christopher M Morris Begoña Indakoetxea Lyduine E Collij Martin Scherer Estrella Morenas-Rodríguez James W Ironside Bart N M van Berckel Daniel Alcolea Heinz Wiendl Samantha L Strickland Pau Pastor Eloy Rodríguez Rodríguez Bradley F Boeve Ronald C Petersen Tanis J Ferman Jay A van Gerpen Marcel J T Reinders Ryan J Uitti Lluís Tárraga Wolfgang Maier Oriol Dols-Icardo Amit Kawalia Maria Carolina Dalmasso Mercè Boada Uwe K Zettl Natasja M van Schoor Marian Beekman Mariet Allen Eliezer Masliah Adolfo López de Munain Alexander Pantelyat Zbigniew K Wszolek Owen A Ross Dennis W Dickson Neill R Graff-Radford David Knopman Rosa Rademakers Afina W Lemstra Yolande A L Pijnenburg Philip Scheltens Thomas Gasser Patrick F Chinnery Bernhard Hemmer Martijn A Huisman Juan Troncoso Fermin Moreno Ellen A Nohr Thorkild I A Sørensen Peter Heutink Pascual Sánchez-Juan Danielle Posthuma Jordi Clarimón Kaare Christensen Nilüfer Ertekin-Taner Sonja W Scholz Alfredo Ramirez Agustín Ruiz Eline Slagboom Wiesje M van der Flier Henne Holstege

Acta Neuropathol 2019 Aug 27;138(2):237-250. Epub 2019 May 27.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00401-019-02026-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660501PMC
August 2019

p.V363I mutation: A rare cause of corticobasal degeneration.

Neurol Genet 2019 Aug 25;5(4):e347. Epub 2019 Jun 25.

Neurodegenerative Disease Research Unit (S.A., M.S.S., S.W.S.), National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD; Movement Disorders and Memory Unit (M.D.F., P.P.), Department of Neurology, University Hospital Mutua de Terrassa, and Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Barcelona, Spain; Laboratory of Neurogenetics (J.D.), National Institutes on Aging, National Institutes of Health, Bethesda, MD; Neurology Service (L.I.), Hospital Universitari Germans Trias, Pujol, Badalona, Spain; Department of Neurology (A.B., A.P., S.W.S.), Johns Hopkins University Medical Center, Baltimore, MD; Newcastle Institute for Ageing (C.M.M.), Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Neurodegenerative Diseases (C.S., T.G.), Center of Neurology, Hertie-Institute for Clinical Brain Research, University of Tuebingen, and German Center for Neurodegenerative Diseases, Germany; Department of Molecular and Clinical Neuroscience (E.J., H.R.M.), Institute of Neurology, University College London, United Kingdom; Department of Pathology (Neuropathology) (O.P., J.T.), Johns Hopkins University Medical Center, Baltimore, MD; Department of Clinical Neurosciences (H.R.M.), Royal Free Campus UCL, Institute of Neurology, London, United Kingdom; Neurological Tissue Bank (E.G.), University of Barcelona-Hospital Clinic, IDIBAPS, Barcelona, Spain; and Institute of Neurology (E.G.), Medical University of Vienna, Austria.

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http://dx.doi.org/10.1212/NXG.0000000000000347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659135PMC
August 2019

Assessment of APOE in atypical parkinsonism syndromes.

Neurobiol Dis 2019 07 21;127:142-146. Epub 2019 Feb 21.

Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588472PMC
July 2019

Heritability and genetic variance of dementia with Lewy bodies.

Neurobiol Dis 2019 07 3;127:492-501. Epub 2019 Apr 3.

Department of Neurodegenerative Diseases, UCL Institute of Neurology, London, UK; UK Dementia Research Institute (UK DRI) at UCL, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588425PMC
July 2019

Genetic analysis of neurodegenerative diseases in a pathology cohort.

Neurobiol Aging 2019 04 17;76:214.e1-214.e9. Epub 2018 Nov 17.

Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391207PMC
April 2019

A comprehensive screening of copy number variability in dementia with Lewy bodies.

Neurobiol Aging 2019 03 24;75:223.e1-223.e10. Epub 2018 Oct 24.

Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK; UK Dementia Research Institute (UK DRI) at UCL, London, UK; Department of Medical Sciences and Institute of Biomedicine, iBiMED, University of Aveiro, Aveiro, Portugal. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01974580183038
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http://dx.doi.org/10.1016/j.neurobiolaging.2018.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541211PMC
March 2019

Neuropathologic, genetic, and longitudinal cognitive profiles in primary age-related tauopathy (PART) and Alzheimer's disease.

Alzheimers Dement 2019 01 11;15(1):8-16. Epub 2018 Dec 11.

Department of Pathology, Division of Neuropathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.07.215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542566PMC
January 2019

Neurotransmitter Imbalance in the Brain and Alzheimer's Disease Pathology.

J Alzheimers Dis 2019 ;72(1):35-43

Clinical and Translational Neuroscience Unit, Laboratory of Behavioural Neuroscience, National Institute on Aging, Baltimore, MD, USA.

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http://dx.doi.org/10.3233/JAD-190577DOI Listing
January 2019

The spectrum of preclinical Alzheimer's disease pathology and its modulation by ApoE genotype.

Neurobiol Aging 2018 11 19;71:72-80. Epub 2018 Jul 19.

Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.07.007DOI Listing
November 2018

Evidence for brain glucose dysregulation in Alzheimer's disease.

Alzheimers Dement 2018 03 19;14(3):318-329. Epub 2017 Oct 19.

Clinical and Translational Neuroscience Unit, Laboratory of Behavioral Neuroscience, National Institute on Aging (NIA), National Institutes of Health (NIH), Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866736PMC
March 2018

Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis.

Am J Pathol 2018 03 15;188(3):739-756. Epub 2017 Dec 15.

Department of Neuroscience, Huffington Center on Aging, Baylor College of Medicine, Houston, Texas; Department of Neurology and Neurosurgery, Huffington Center on Aging, Baylor College of Medicine, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840490PMC
March 2018

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study.

Lancet Neurol 2018 01 16;17(1):64-74. Epub 2017 Dec 16.

UK Dementia Research Institute, University College London, London, UK; Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK; Department of Medical Sciences and Institute of Biomedicine, iBiMED, University of Aveiro, Aveiro, Portugal. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30400-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805394PMC
January 2018

Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study.

PLoS Med 2018 01 25;15(1):e1002482. Epub 2018 Jan 25.

Clinical and Translational Neuroscience Unit, Laboratory of Behavioral Neuroscience, National Institute on Aging (NIA), National Institutes of Health (NIH), Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1002482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784884PMC
January 2018

Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models.

Oncotarget 2017 Dec 11;8(63):106721-106739. Epub 2017 Oct 11.

Division of Pharmacology, Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Samsung Biomedical Research Institute, Suwon 440-746, Republic of Korea.

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http://dx.doi.org/10.18632/oncotarget.21828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739769PMC
December 2017

Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons.

eNeuro 2016 Jul-Aug;3(4). Epub 2016 Sep 2.

Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205; Adrienne Helis Malvin Medical Research Foundation, New Orleans, Louisiana 70130-2685; Diana Helis Henry Medical Research Foundation, New Orleans, Louisiana 70130-2685; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

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http://dx.doi.org/10.1523/ENEURO.0183-16.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011687PMC
October 2017

C9orf72 Hexanucleotide Repeat Analysis in Cases with Pathologically Confirmed Dementia with Lewy Bodies.

Neurodegener Dis 2016 31;16(5-6):370-2. Epub 2016 May 31.

Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, Bethesda, Md., The Commonwealth Medical College, Scranton, Pa., USA.

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http://dx.doi.org/10.1159/000445872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011449PMC
September 2017

TRIAD3/RNF216 mutations associated with Gordon Holmes syndrome lead to synaptic and cognitive impairments via Arc misregulation.

Aging Cell 2017 04 20;16(2):281-292. Epub 2016 Dec 20.

Signature Program in Neuroscience and Behavioral Disorders, Duke-NUS Medical School Singapore, 8 College Road, Singapore, 169857, Singapore.

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http://dx.doi.org/10.1111/acel.12551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334534PMC
April 2017

Mutant Huntingtin Disrupts the Nuclear Pore Complex.

Neuron 2017 Apr;94(1):93-107.e6

Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.03.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595097PMC
April 2017

Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study.

PLoS Med 2017 Mar 21;14(3):e1002266. Epub 2017 Mar 21.

Clinical and Translational Neuroscience Unit, Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1002266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360226PMC
March 2017

ADORA1 mutations are not a common cause of Parkinson's disease and dementia with Lewy bodies.

Mov Disord 2017 02 17;32(2):298-299. Epub 2016 Dec 17.

Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1002/mds.26886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318291PMC
February 2017

Gait function and locus coeruleus Lewy body pathology in 51 Parkinson's disease patients.

Parkinsonism Relat Disord 2016 12 25;33:102-106. Epub 2016 Sep 25.

Movement Disorders Division, Dept. of Neurology, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Meyer 6-181, Baltimore, MD, 21287, United States; Morris K. Udall Parkinson's Disease Research Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States.

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http://dx.doi.org/10.1016/j.parkreldis.2016.09.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154818PMC
December 2016

Next-generation sequencing reveals substantial genetic contribution to dementia with Lewy bodies.

Neurobiol Dis 2016 Oct 14;94:55-62. Epub 2016 Jun 14.

Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2016.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983488PMC
October 2016

Quantitative Proteomic Analysis Reveals Similarities between Huntington's Disease (HD) and Huntington's Disease-Like 2 (HDL2) Human Brains.

J Proteome Res 2016 09 3;15(9):3266-83. Epub 2016 Aug 3.

Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine , 600 North Wolfe Street, CMSC 8-121, Baltimore, Maryland 21287, United States.

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http://dx.doi.org/10.1021/acs.jproteome.6b00448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555151PMC
September 2016

A rapidly progressive dementia case with pathological diagnosis of FTLD-UPS.

Acta Neuropathol 2016 08 6;132(2):309-11. Epub 2016 Jun 6.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.

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http://dx.doi.org/10.1007/s00401-016-1584-7DOI Listing
August 2016

Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease.

Hum Mol Genet 2016 08 4;25(16):3454-3466. Epub 2016 Jul 4.

Department of Microbiology, Immunology, & Molecular Genetics, University of California Los Angeles, Los Angeles, CA, USA

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http://dx.doi.org/10.1093/hmg/ddw187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179942PMC
August 2016

Lysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity.

PLoS One 2015 2;10(12):e0143854. Epub 2015 Dec 2.

Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0143854PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668030PMC
June 2016

RAN Translation in Huntington Disease.

Neuron 2015 Nov;88(4):667-77

Center for NeuroGenetics, University of Florida, Gainesville, FL 32610, USA; Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL 32610, USA; Department of Neurology, University of Florida, Gainesville, FL 32610, USA; Genetics Institute, University of Florida, Gainesville, FL 32610, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2015.10.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684947PMC
November 2015

Alzheimer Lesions in the Autopsied Brains of People 30 to 50 Years of Age.

Cogn Behav Neurol 2015 Sep;28(3):144-52

*Department of Pathology, Division of Neuropathology §Department of Neurology, Johns Hopkins University School of Medicine †Lieber Institute for Brain Development, Baltimore, Maryland ‡Office of the Chief Medical Examiner, Baltimore, Maryland.

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http://dx.doi.org/10.1097/WNN.0000000000000071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588069PMC
September 2015

TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD.

Science 2015 Aug;349(6248):650-5

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205-2196, USA. Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205-2196, USA.

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http://dx.doi.org/10.1126/science.aab0983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825810PMC
August 2015

PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease.

Neurology 2015 Mar 6;84(10):972-80. Epub 2015 Feb 6.

From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (

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http://www.neurology.org/content/early/2015/02/06/WNL.000000
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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000133
Publisher Site
http://dx.doi.org/10.1212/WNL.0000000000001332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352096PMC
March 2015

α-Synuclein-induced dopaminergic neurodegeneration in a rat model of Parkinson's disease occurs independent of ATP13A2 (PARK9).

Neurobiol Dis 2015 Jan 18;73:229-43. Epub 2014 Oct 18.

Laboratory of Molecular Neurodegenerative Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland; Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI 49503, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2014.10.007DOI Listing
January 2015

The problem of axonal injury in the brains of veterans with histories of blast exposure.

Acta Neuropathol Commun 2014 Nov 25;2:153. Epub 2014 Nov 25.

Department of Pathology, Division of Neuropathology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.

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http://dx.doi.org/10.1186/s40478-014-0153-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260204PMC
November 2014

Hippocampal sclerosis dementia with the C9ORF72 hexanucleotide repeat expansion.

Neurobiol Aging 2014 Oct 18;35(10):2419.e17-21. Epub 2014 Apr 18.

Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01974580140031
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http://dx.doi.org/10.1016/j.neurobiolaging.2014.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087047PMC
October 2014

Conformational specificity of the C4F6 SOD1 antibody; low frequency of reactivity in sporadic ALS cases.

Acta Neuropathol Commun 2014 May 14;2:55. Epub 2014 May 14.

Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, McKnight Brain Institute, University of Florida, Box 100159, Gainesville, FL 32610, USA.

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http://dx.doi.org/10.1186/2051-5960-2-55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035506PMC
May 2014

Mild cognitive impairment and asymptomatic Alzheimer disease subjects: equivalent β-amyloid and tau loads with divergent cognitive outcomes.

J Neuropathol Exp Neurol 2014 Apr;73(4):295-304

From the Departments of Pathology (DI, OP, GR, BC, JT), and Neurology (RO, JT), Johns Hopkins University School of Medicine; and Laboratory of Personality and Cognition, Intramural Research Program, National Institute on Aging, National Institutes of Health (SMR, ABZ, YA), Baltimore, Maryland; and Neuropathology Research, Biomedical Research Institute of New Jersey, Cedar Knolls, New Jersey (DI).

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http://dx.doi.org/10.1097/NEN.0000000000000052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062187PMC
April 2014

RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia.

Proc Natl Acad Sci U S A 2013 Dec 18;110(51):E4968-77. Epub 2013 Nov 18.

Department of Molecular Genetics and Microbiology, Department of Neurology, and Department of Neuroscience, Center for NeuroGenetics, Genetics Institute, College of Medicine, University of Florida, Gainesville, FL 32610.

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http://dx.doi.org/10.1073/pnas.1315438110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870665PMC
December 2013

Feasibility of creating a high-resolution 3D diffusion tensor imaging based atlas of the human brainstem: a case study at 11.7 T.

Neuroimage 2013 Jul 4;74:117-27. Epub 2013 Feb 4.

Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2013.01.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615045PMC
July 2013

Hippocampal sclerosis dementia: An amnesic variant of frontotemporal degeneration.

Dement Neuropsychol 2013 Mar;7(1):83-87

Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867983PMC
http://dx.doi.org/10.1590/s1980-57642013dn70100013DOI Listing
March 2013

Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease.

Mov Disord 2012 Sep 13;27(11):1379-86. Epub 2012 Sep 13.

Division of Neuropathology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1002/mds.25159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3455126PMC
September 2012

Neurodegenerative phenotypes in an A53T α-synuclein transgenic mouse model are independent of LRRK2.

Hum Mol Genet 2012 Jun 21;21(11):2420-31. Epub 2012 Feb 21.

NeuroRegeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/dds057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349422PMC
June 2012

PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity.

Hum Mol Genet 2012 Apr 20;21(8):1725-43. Epub 2011 Dec 20.

Laboratory of Molecular Neurodegenerative Research, School of Life Sciences, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1093/hmg/ddr606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465694PMC
April 2012

Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo.

J Neurosci 2012 Mar;32(10):3301-5

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.5368-11.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548448PMC
March 2012

Identification of novel GDNF isoforms and cis-antisense GDNFOS gene and their regulation in human middle temporal gyrus of Alzheimer disease.

J Biol Chem 2011 Dec 11;286(52):45093-102. Epub 2011 Nov 11.

Neural Protection and Regeneration Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Department of Health and Social Services, Baltimore, Maryland21224, USA.

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http://dx.doi.org/10.1074/jbc.M111.310250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247946PMC
December 2011

Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function.

Proc Natl Acad Sci U S A 2010 Sep 7;107(38):16691-6. Epub 2010 Sep 7.

Neuroregeneration Program, Institute for Cell Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.1006083107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944759PMC
September 2010

ApoE4 disrupts sterol and sphingolipid metabolism in Alzheimer's but not normal brain.

Neurobiol Aging 2009 Apr 20;30(4):591-9. Epub 2007 Sep 20.

Department of Neurology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2007.07.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758772PMC
April 2009

S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease.

Proc Natl Acad Sci U S A 2009 Mar 9;106(12):4900-5. Epub 2009 Mar 9.

Department of Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong.

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http://dx.doi.org/10.1073/pnas.0810595106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660786PMC
March 2009

Effect of infarcts on dementia in the Baltimore longitudinal study of aging.

Ann Neurol 2008 Aug;64(2):168-76

Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/ana.21413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694129PMC
August 2008

Neuronal hypertrophy in asymptomatic Alzheimer disease.

J Neuropathol Exp Neurol 2008 Jun;67(6):578-89

Division of Neuropathology, Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1097/NEN.0b013e3181772794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518071PMC
June 2008

Morphometry of the human substantia nigra in ageing and Parkinson's disease.

Acta Neuropathol 2008 Apr 23;115(4):461-70. Epub 2008 Feb 23.

Neuropathology, Johns Hopkins School of Medicine, Ross Research Building 555, 720 Rutland Avenue, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1007/s00401-008-0352-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2431149PMC
April 2008

A comparison of huntington disease and huntington disease-like 2 neuropathology.

J Neuropathol Exp Neurol 2008 Apr;67(4):366-74

Division of Neurobiology, Department of Psychiatry, John Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1097/NEN.0b013e31816b4aeeDOI Listing
April 2008

Neurexin 3 polymorphisms are associated with alcohol dependence and altered expression of specific isoforms.

Hum Mol Genet 2007 Dec 4;16(23):2880-91. Epub 2007 Sep 4.

Molecular Neurobiology Branch, NIDA-IRP, NIH, DHSS, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1093/hmg/ddm247DOI Listing
December 2007

Resistance to Alzheimer's pathology is associated with nuclear hypertrophy in neurons.

Neurobiol Aging 2007 Oct 28;28(10):1484-92. Epub 2007 Jun 28.

Division of Neuropathology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2007.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694127PMC
October 2007

Abeta deposition is associated with enhanced cortical alpha-synuclein lesions in Lewy body diseases.

Neurobiol Aging 2005 Aug-Sep;26(8):1183-92. Epub 2004 Dec 28.

Department of Pathology (Neuropathology), Johns Hopkins University School of Medicine, Ross Building 558, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2004.10.006DOI Listing
August 2005

Alpha-synuclein lesions in normal aging, Parkinson disease, and Alzheimer disease: evidence from the Baltimore Longitudinal Study of Aging (BLSA).

J Neuropathol Exp Neurol 2005 Feb;64(2):156-62

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2196, USA.

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http://dx.doi.org/10.1093/jnen/64.2.156DOI Listing
February 2005

S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function.

Science 2004 May 22;304(5675):1328-31. Epub 2004 Apr 22.

Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1126/science.1093891DOI Listing
May 2004