Olga Buzovetsky

Olga Buzovetsky

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Olga Buzovetsky

Olga Buzovetsky

Publications by authors named "Olga Buzovetsky"

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14Publications

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Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML.

Authors:
Thomas Oellerich Constanze Schneider Dominique Thomas Kirsten M Knecht Olga Buzovetsky Lars Kaderali Christoph Schliemann Hanibal Bohnenberger Linus Angenendt Wolfgang Hartmann Eva Wardelmann Tamara Rothenburger Sebastian Mohr Sebastian Scheich Federico Comoglio Anne Wilke Philipp Ströbel Hubert Serve Martin Michaelis Nerea Ferreirós Gerd Geisslinger Yong Xiong Oliver T Keppler Jindrich Cinatl

Nat Commun 2019 Aug 2;10(1):3475. Epub 2019 Aug 2.

Institute of Medical Virology, University of Frankfurt, Frankfurt, 60590, Germany.

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http://dx.doi.org/10.1038/s41467-019-11413-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677770PMC
August 2019

A Noncanonical Basic Motif of Epstein-Barr Virus ZEBRA Protein Facilitates Recognition of Methylated DNA, High-Affinity DNA Binding, and Lytic Activation.

Authors:
Erin Weber Olga Buzovetsky Lee Heston Kuan-Ping Yu Kirsten M Knecht Ayman El-Guindy George Miller Yong Xiong

J Virol 2019 Jul 28;93(14). Epub 2019 Jun 28.

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, USA

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http://dx.doi.org/10.1128/JVI.00724-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600195PMC
July 2019

Conformational switches control early maturation of the eukaryotic small ribosomal subunit.

Authors:
Mirjam Hunziker Jonas Barandun Olga Buzovetsky Caitlin Steckler Henrik Molina Sebastian Klinge

Elife 2019 06 17;8. Epub 2019 Jun 17.

Laboratory of Protein and Nucleic Acid Chemistry, The Rockefeller University, New York, United States.

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http://dx.doi.org/10.7554/eLife.45185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579516PMC
June 2019

The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1.

Authors:
Kirsten M Knecht Olga Buzovetsky Constanze Schneider Dominique Thomas Vishok Srikanth Lars Kaderali Florentina Tofoleanu Krystle Reiss Nerea Ferreirós Gerd Geisslinger Victor S Batista Xiaoyun Ji Jindrich Cinatl Oliver T Keppler Yong Xiong

Proc Natl Acad Sci U S A 2018 10 10;115(43):E10022-E10031. Epub 2018 Oct 10.

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520;

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http://dx.doi.org/10.1073/pnas.1805593115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205433PMC
October 2018

SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4 T Cells.

Authors:
Jenna M Antonucci Sun Hee Kim Corine St Gelais Serena Bonifati Tai-Wei Li Olga Buzovetsky Kirsten M Knecht Alice A Duchon Yong Xiong Karin Musier-Forsyth Li Wu

J Virol 2018 08 17;92(15). Epub 2018 Jul 17.

Center for Retrovirus Research, The Ohio State University, Columbus, Ohio, USA

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http://jvi.asm.org/lookup/doi/10.1128/JVI.00292-18
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http://dx.doi.org/10.1128/JVI.00292-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052313PMC
August 2018

Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies.

Authors:
Samantha J Ziegler Chang Liu Mark Landau Olga Buzovetsky Belete A Desimmie Qi Zhao Tomoaki Sasaki Ryan C Burdick Vinay K Pathak Karen S Anderson Yong Xiong

PLoS One 2018 29;13(3):e0195048. Epub 2018 Mar 29.

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0195048PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875850PMC
July 2018

SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways.

Authors:
Shuliang Chen Serena Bonifati Zhihua Qin Corine St Gelais Karthik M Kodigepalli Bradley S Barrett Sun Hee Kim Jenna M Antonucci Katherine J Ladner Olga Buzovetsky Kirsten M Knecht Yong Xiong Jacob S Yount Denis C Guttridge Mario L Santiago Li Wu

Proc Natl Acad Sci U S A 2018 04 2;115(16):E3798-E3807. Epub 2018 Apr 2.

Center for Retrovirus Research, Department of Veterinary Biosciences, Ohio State University, Columbus, OH 43210;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1801213115
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http://dx.doi.org/10.1073/pnas.1801213115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910870PMC
April 2018

A Cyclin-Binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation.

Authors:
Corine St Gelais Sun Hee Kim Victoria V Maksimova Olga Buzovetsky Kirsten M Knecht Caitlin Shepard Baek Kim Yong Xiong Li Wu

J Virol 2018 03 26;92(6). Epub 2018 Feb 26.

Center for Retrovirus Research, Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA

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http://dx.doi.org/10.1128/JVI.01787-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827405PMC
March 2018

The SAM domain of mouse SAMHD1 is critical for its activation and regulation.

Authors:
Olga Buzovetsky Chenxiang Tang Kirsten M Knecht Jenna M Antonucci Li Wu Xiaoyun Ji Yong Xiong

Nat Commun 2018 01 29;9(1):411. Epub 2018 Jan 29.

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA.

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http://dx.doi.org/10.1038/s41467-017-02783-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788916PMC
January 2018

Role of the Pif1-PCNA Complex in Pol δ-Dependent Strand Displacement DNA Synthesis and Break-Induced Replication.

Authors:
Olga Buzovetsky Youngho Kwon Nhung Tuyet Pham Claire Kim Grzegorz Ira Patrick Sung Yong Xiong

Cell Rep 2017 Nov;21(7):1707-1714

Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.10.079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842794PMC
November 2017

Mechanisms of activation and inhibition of Zika virus NS2B-NS3 protease.

Authors:
Xia Chen Kailin Yang Chen Wu Cheng Chen Can Hu Olga Buzovetsky Zefang Wang Xiaoyun Ji Yong Xiong Haitao Yang

Cell Res 2016 11 18;26(11):1260-1263. Epub 2016 Oct 18.

School of Life Sciences, Tianjin University, Tianjin 300072, China.

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http://dx.doi.org/10.1038/cr.2016.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099865PMC
November 2016

Expanding the clinical, allelic, and locus heterogeneity of retinal dystrophies.

Authors:
Nisha Patel Mohammed A Aldahmesh Hisham Alkuraya Shamsa Anazi Hadeel Alsharif Arif O Khan Asma Sunker Saleh Al-Mohsen Emad B Abboud Sawsan R Nowilaty Mohammed Alowain Hamad Al-Zaidan Bandar Al-Saud Ali Alasmari Ghada M H Abdel-Salam Mohamed Abouelhoda Firdous M Abdulwahab Niema Ibrahim Ewa Naim Banan Al-Younes Abeer E AlMostafa Abdulelah AlIssa Mais Hashem Olga Buzovetsky Yong Xiong Dorota Monies Nada Altassan Ranad Shaheen Selwa A F Al-Hazzaa Fowzan S Alkuraya

Genet Med 2016 06 10;18(6):554-62. Epub 2015 Sep 10.

Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia;

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http://dx.doi.org/10.1038/gim.2015.127DOI Listing
June 2016

Promotion of RAD51-Mediated Homologous DNA Pairing by the RAD51AP1-UAF1 Complex.

Authors:
Fengshan Liang Simonne Longerich Adam S Miller Caroline Tang Olga Buzovetsky Yong Xiong David G Maranon Claudia Wiese Gary M Kupfer Patrick Sung

Cell Rep 2016 06 26;15(10):2118-2126. Epub 2016 May 26.

Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247163056
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http://dx.doi.org/10.1016/j.celrep.2016.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381662PMC
June 2016

Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway.

Authors:
Woo Joo Guozhou Xu Nicole S Persky Agata Smogorzewska Derek G Rudge Olga Buzovetsky Stephen J Elledge Nikola P Pavletich

Science 2011 Jul;333(6040):312-6

Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1126/science.1205805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310437PMC
July 2011