Publications by authors named "Olga A Sedelnikova"

31Publications

H2AX phosphorylation in response to DNA double-strand break formation during bystander signalling: effect of microRNA knockdown.

Radiat Prot Dosimetry 2011 Feb 23;143(2-4):264-9. Epub 2010 Dec 23.

Laboratory of Molecular Pharmacology, Center for Cancer Research, NCI, NIH, 9000 Rockville Pike, Bethesda, MD 20892, USA.

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https://academic.oup.com/rpd/article-lookup/doi/10.1093/rpd/
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http://dx.doi.org/10.1093/rpd/ncq470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108274PMC
February 2011

Tumors induce complex DNA damage in distant proliferative tissues in vivo.

Proc Natl Acad Sci U S A 2010 Oct 20;107(42):17992-7. Epub 2010 Sep 20.

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.1008260107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964229PMC
October 2010

microRNAome changes in bystander three-dimensional human tissue models suggest priming of apoptotic pathways.

Carcinogenesis 2010 Oct 19;31(10):1882-8. Epub 2010 Jul 19.

Department of Biological Sciences, University of Lethbridge, 4401 University Drive, Lethbridge, Alberta, T1K 3M4 Canada.

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http://dx.doi.org/10.1093/carcin/bgq119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950932PMC
October 2010

Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells.

Aging (Albany NY) 2009 Feb 4;1(2):212-8. Epub 2009 Feb 4.

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806003PMC
http://dx.doi.org/10.18632/aging.100019DOI Listing
February 2009

Role of oxidatively induced DNA lesions in human pathogenesis.

Mutat Res 2010 Apr-Jun;704(1-3):152-9. Epub 2010 Jan 8.

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, 9000 Rockville Pike, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.mrrev.2009.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074954PMC
August 2010

γ-H2AX as a biomarker of DNA damage induced by ionizing radiation in human peripheral blood lymphocytes and artificial skin.

Adv Space Res 2009 ;43(8):1171-1178

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, D.H.H.S., Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1016/j.asr.2008.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735274PMC
January 2009

H2AX: functional roles and potential applications.

Chromosoma 2009 Dec 26;118(6):683-92. Epub 2009 Aug 26.

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s00412-009-0234-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094848PMC
December 2009

Intercellular communication of cellular stress monitored by gamma-H2AX induction.

Carcinogenesis 2009 Oct 3;30(10):1686-95. Epub 2009 Aug 3.

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20952, USA.

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http://dx.doi.org/10.1093/carcin/bgp192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757548PMC
October 2009

Where did they come from? The origin of endogenous gamma-H2AX foci in tumor cells.

Cell Cycle 2009 Aug 1;8(15):2324. Epub 2009 Aug 1.

National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.4161/cc.8.15.9311DOI Listing
August 2009

Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence.

Epigenetics Chromatin 2008 Nov 3;1(1). Epub 2008 Nov 3.

Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, Rockville Pike, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1186/1756-8935-1-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584625PMC
November 2008

GammaH2AX and cancer.

Nat Rev Cancer 2008 Dec 13;8(12):957-67. Epub 2008 Nov 13.

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/nrc2523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094856PMC
December 2008

Accumulation of oxidatively induced clustered DNA lesions in human tumor tissues.

Mutat Res 2009 Mar 2;674(1-2):131-6. Epub 2008 Oct 2.

Department of Biology, Thomas Harriot College of Arts and Sciences, East Carolina University, Greenville, NC 27858, USA.

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http://dx.doi.org/10.1016/j.mrgentox.2008.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944316PMC
March 2009

Delayed kinetics of DNA double-strand break processing in normal and pathological aging.

Aging Cell 2008 Jan 19;7(1):89-100. Epub 2007 Dec 19.

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://doi.wiley.com/10.1111/j.1474-9726.2007.00354.x
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http://dx.doi.org/10.1111/j.1474-9726.2007.00354.xDOI Listing
January 2008

gamma-H2AX in bystander cells: not just a radiation-triggered event, a cellular response to stress mediated by intercellular communication.

Cell Cycle 2007 Sep 5;6(18):2210-2. Epub 2007 Jul 5.

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20895, USA.

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http://dx.doi.org/10.4161/cc.6.18.4682DOI Listing
September 2007

DNA double-strand breaks form in bystander cells after microbeam irradiation of three-dimensional human tissue models.

Cancer Res 2007 May;67(9):4295-302

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-4442DOI Listing
May 2007

GammaH2AX in cancer cells: a potential biomarker for cancer diagnostics, prediction and recurrence.

Cell Cycle 2006 Dec 15;5(24):2909-13. Epub 2006 Dec 15.

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.4161/cc.5.24.3569DOI Listing
December 2006

The phosphorylation status of PAS-B distinguishes HIF-1alpha from HIF-2alpha in NBS1 repression.

EMBO J 2006 Oct 5;25(20):4784-94. Epub 2006 Oct 5.

Laboratory of Human Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1038/sj.emboj.7601369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618093PMC
October 2006

Techniques for gamma-H2AX detection.

Methods Enzymol 2006 ;409:236-50

Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, USA.

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http://dx.doi.org/10.1016/S0076-6879(05)09014-2DOI Listing
August 2006

DNA damage produced by 125I-triplex-forming oligonucleotides as a measure of their successful delivery into cell nuclei.

Ann N Y Acad Sci 2005 Nov;1058:140-50

Department of Nuclear Medicine, Clinical Center, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1196/annals.1359.022DOI Listing
November 2005

Ionizing radiation induces DNA double-strand breaks in bystander primary human fibroblasts.

Oncogene 2005 Nov;24(49):7257-65

Department of Nuclear Medicine, Clinical Center, NIH, 9000 Rockville Pike, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1038/sj.onc.1208886DOI Listing
November 2005

Assessment of DNA damage produced by 125I-triplex-forming oligonucleotides in cells.

Int J Radiat Biol 2004 Nov-Dec;80(11-12):927-31

NIH/NMD, 10 Center Dr., Room 4D45, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1080/09553000400017648DOI Listing
April 2005

Two-dimensional gel analysis of histones and other H2AX-related methods.

Methods Enzymol 2004 ;375:76-88

Laboratory of Molecular Pharmacology, National Cancer Institute, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1016/s0076-6879(03)75005-8DOI Listing
March 2004

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks.

Nat Cell Biol 2004 Feb;6(2):168-70

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/ncb1095DOI Listing
February 2004

Characteristics of gamma-H2AX foci at DNA double-strand breaks sites.

Biochem Cell Biol 2003 Jun;81(3):123-9

Laboratory of Molecular Pharmacology, National Cancer Institute, National Insitutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1139/o03-042DOI Listing
June 2003

Histone H2AX in DNA damage and repair.

Cancer Biol Ther 2003 May-Jun;2(3):233-5

Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.4161/cbt.2.3.373DOI Listing
December 2003

Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody.

Radiat Res 2002 Oct;158(4):486-92

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1667/0033-7587(2002)158[0486:qdoiid]2.0.co;2DOI Listing
October 2002