Publications by authors named "Ole Gjoerup"

30Publications

Identification and Utilization of Biomarkers to Predict Response to Immune Checkpoint Inhibitors.

AAPS J 2020 Oct 14;22(6):132. Epub 2020 Oct 14.

Foundation Medicine, Inc, Cambridge, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1208/s12248-020-00514-4DOI Listing
October 2020

Characterization of a single chain variable fragment of nivolumab that targets PD-1 and blocks PD-L1 binding.

Protein Expr Purif 2021 Jan 25;177:105766. Epub 2020 Sep 25.

Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA, 02111, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pep.2020.105766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518118PMC
January 2021

Analysis of JC virus DNA replication using a quantitative and high-throughput assay.

Virology 2014 Nov 24;468-470:113-125. Epub 2014 Aug 24.

Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, MA 02111, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.virol.2014.07.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658058PMC
November 2014

Simian virus 40 large T antigen induces IFN-stimulated genes through ATR kinase.

J Immunol 2014 Jun 5;192(12):5933-42. Epub 2014 May 5.

Cancer Virology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1303470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078001PMC
June 2014

Viral interference with DNA repair by targeting of the single-stranded DNA binding protein RPA.

PLoS Pathog 2013 Oct 24;9(10):e1003725. Epub 2013 Oct 24.

Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, United States of America ; Program in Molecular Microbiology, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1003725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812037PMC
October 2013

Replication stress and mitotic dysfunction in cells expressing simian virus 40 large T antigen.

J Virol 2013 Dec 25;87(24):13179-92. Epub 2013 Sep 25.

Molecular Oncology Research Institute, Tufts Medical Center, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.02224-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838287PMC
December 2013

Formation of covalently modified folding intermediates of simian virus 40 Vp1 in large T antigen-expressing cells.

J Virol 2013 May 20;87(9):5053-64. Epub 2013 Feb 20.

Department of Molecular, Cell and Developmental Biology and Molecular Biology Institute, University of California at Los Angeles, Los Angeles, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.00955-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624288PMC
May 2013

Functional connection between Rad51 and PML in homology-directed repair.

PLoS One 2011 5;6(10):e25814. Epub 2011 Oct 5.

Cancer Virology Program, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0025814PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187806PMC
February 2012

DNA damage response signaling triggers nuclear localization of the chicken anemia virus protein Apoptin.

J Virol 2011 Dec 21;85(23):12638-49. Epub 2011 Sep 21.

Goodman Cancer Research Centre, McGill University, Montréal, QC, Canada H3A 1A3.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.05009-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209404PMC
December 2011

Cellular and viral factors regulating Merkel cell polyomavirus replication.

PLoS One 2011 22;6(7):e22468. Epub 2011 Jul 22.

Cancer Virology Program, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022468PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142164PMC
December 2011

Multiple DNA damage signaling and repair pathways deregulated by simian virus 40 large T antigen.

J Virol 2010 Aug 2;84(16):8007-20. Epub 2010 Jun 2.

University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.00334-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916509PMC
August 2010

Update on human polyomaviruses and cancer.

Adv Cancer Res 2010 ;106:1-51

Cancer Virology Program, Hillman Cancer Research Pavilion, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0065-230X(10)06001-XDOI Listing
July 2010

Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding.

J Virol 2009 Jan 15;83(1):117-27. Epub 2008 Oct 15.

Hillman Cancer Center, Research Pavilion Suite 1.8, 5117 Centre Avenue, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.01515-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612341PMC
January 2009

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus.

Proc Natl Acad Sci U S A 2008 Oct 23;105(42):16272-7. Epub 2008 Sep 23.

Molecular Virology Program, University of Pittsburgh Cancer Institute, University of Pittsburgh, 5117 Centre Avenue, Suite 1.8, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0806526105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551627PMC
October 2008

Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner.

Proc Natl Acad Sci U S A 2007 Nov 15;104(48):19011-6. Epub 2007 Nov 15.

Department of Biochemistry, Sackler School of Graduate Biomedical Sciences, School of Medicine, Tufts University, Boston, MA 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0706696104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141899PMC
November 2007

Bub1: escapades in a cellular world.

Cell Cycle 2007 Jul 25;6(14):1699-704. Epub 2007 May 25.

Department of Cancer Biology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.6.14.4493DOI Listing
July 2007

Preparation of monoclonal antibodies against the spindle checkpoint kinase Bub1.

Hybridoma (Larchmt) 2007 Jun;26(3):140-7

Ludwig Institute for Cancer Research, Royal Free and University College School of Medicine, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/hyb.2007.003DOI Listing
June 2007

Surveillance mechanism linking Bub1 loss to the p53 pathway.

Proc Natl Acad Sci U S A 2007 May 8;104(20):8334-9. Epub 2007 May 8.

Molecular Virology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0703164104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895950PMC
May 2007

The p110alpha isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation.

Proc Natl Acad Sci U S A 2006 Oct 23;103(44):16296-300. Epub 2006 Oct 23.

Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://www.pnas.org/cgi/doi/10.1073/pnas.0607899103
Publisher Site
http://dx.doi.org/10.1073/pnas.0607899103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637576PMC
October 2006

Activation of p21-activated kinase 6 by MAP kinase kinase 6 and p38 MAP kinase.

J Biol Chem 2005 Feb 18;280(5):3323-30. Epub 2004 Nov 18.

Cancer Biology Program, Hematology-Oncology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M406701200DOI Listing
February 2005

The serine/threonine kinase cyclin G-associated kinase regulates epidermal growth factor receptor signaling.

Proc Natl Acad Sci U S A 2004 Jul 6;101(28):10296-301. Epub 2004 Jul 6.

Department of Cancer Biology, Dana-Farber Cancer Institute, and Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0403175101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC478566PMC
July 2004

Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1.

Proc Natl Acad Sci U S A 2004 Jan 19;101(4):947-52. Epub 2004 Jan 19.

Ludwig Institute for Cancer Research, Royal Free and University College School of Medicine, Courtauld Building, 91 Riding House Street, London W1W 7BS, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0308006100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC327122PMC
January 2004

Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase.

Cancer Cell 2003 May;3(5):483-95

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s1535-6108(03)00088-6DOI Listing
May 2003