Publications by authors named "Oldřich Motyka"

15 Publications

  • Page 1 of 1

Multivariate assessment of atmospheric deposition studies in Bulgaria based on moss biomonitors: trends between the 2005/2006 and 2015/2016 surveys.

Environ Sci Pollut Res Int 2020 Nov 9;27(31):39330-39342. Epub 2020 Jul 9.

Sector of Neutron Activation Analysis and Applied Research, Division of Nuclear Physics, FLNP, Joint Institute for Nuclear Research, Dubna, Russian Federation, 141980.

This study aims to investigate the changes in atmospheric deposition trends in Bulgaria, studied using the moss biomonitoring technique since 1995. For the first time, a paired (site-wise) comparison was performed after a critical review of the sampling networks and adjusting for location, the distance between the sampling points, and moss species. Data from the 2005/2006 and 2015/2016 moss surveys were chosen as instrumental neutron activation analysis was employed in both to determine the content of 34 elements (Al, As, Ba, Br, Са, Ce, Cl, Со, Cr, Cs, Fe, Hf, I, K, La, Mn, Na, Nd, Ni, Rb, Sb, Sc, Se, Sr, Ta, Tb, Th, Ti, Tm, U, V, W, Yb, Zn). In addition, Cd, Cu, and Pb were determined using complementary analytical methods: inductively coupled plasma atomic emission spectroscopy in 2015/2016 and atomic absorption spectroscopy in 2005/2006. For the subset of 57 routinely sampled locations in Bulgaria, hierarchical clustering on principal components and multiple factor analysis (MFA) were applied to assess the spatial trends in the 10 years elapsed between the surveys, as well as to characterise the origin of the determined elements. Elevation and distance between the sampling points were used as additional variables in the multiple factor analysis plane to ascertain their effect on the overall variance in the datasets. Distribution maps were constructed to illustrate the deposition patterns for the pollutant Pb. The results were consistent with decreased industrial output in the country, increased coal combustion and transport pollution, and construction of roads.
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http://dx.doi.org/10.1007/s11356-020-10005-wDOI Listing
November 2020

Moss biomonitoring and air pollution modelling on a regional scale: delayed reflection of industrial pollution in moss in a heavily polluted region?

Environ Sci Pollut Res Int 2020 Sep 8;27(26):32569-32578. Epub 2020 Jun 8.

Frank Laboratory of Neutron Physics, Joint Institute for Nuclear Research (JINR), Joliot-Curie 6, Dubna, Moscow Region, Russia, 141980.

A passive biomonitoring survey using terrestrial mosses was performed in a heavily polluted industrial region on the border between Czechia and Poland in a regular grid of 41 sampling points. The concentrations of 38 elements were determined in the moss samples, using Neutron Activation Analysis (NAA). Simultaneously, air pollution modelling was performed using the Czech reference methodology Symos'97 for the year of the sampling (2015) and 3 years prior (2012) in order to compare the results of both the approaches and evaluate the credibility of the moss biomonitoring method. The NAA results were transformed according to the principles of compositional data analysis and assessed using hierarchical clustering on principal components. The resulting clusters were compared with the results of air pollution modelling using one-way analysis of variance. The association of determined clusters with the pollution from industrial sources was confirmed only for the results of the 2012 modelling. This validates the complementarity of the air pollution modelling and the moss biomonitoring, ascertains the moss biomonitoring as a valid method for long-term pollution assessment and confirms one of the fundamentals of moss biomonitoring, the reflection of the atmospheric conditions prevailing in the period before the sampling.
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http://dx.doi.org/10.1007/s11356-020-09466-wDOI Listing
September 2020

Metal particles in mucus and hypertrophic tissue of the inferior nasal turbinates from the human upper respiratory tract.

Environ Sci Pollut Res Int 2020 Aug 15;27(22):28146-28154. Epub 2020 May 15.

Center of Advanced Innovation Technologies, VŠB-Technical University of Ostrava, 17. listopadu 15/2172, Poruba, 708 33, Ostrava, Czech Republic.

Mucosal surfaces are the first mechanical barrier preventing the entry of foreign particles into the organism. The study addresses the detection and analysis of metal-based solid particles in cytological mucus samples from the surface of human hypertrophic tissue in the inferior nasal turbinates in patients diagnosed with chronic rhinitis. Solid particles were characterized by scanning electron microscopy and Raman microspectroscopy; all the biological samples were also subjected to vibration magnetometry. Since the upper airways are the first part of the respiratory tract, which is exposed to inhaled particles, it can be assumed that inhaled particles may be partially deposited in this region. Scanning electron microscopy revealed the presence of metal-based solid particles/clusters in the majority of the analysed cytological mucus samples and also in hypertrophic tissues; in all groups, the particles were of submicron size. Raman microspectroscopy detected the presence of particles/clusters based on amorphous carbon, graphite, calcium carbonate, anatase and barite only in the hypertrophic tissue. The obtained results show that the composition of some of the solid particles (i.e. Ba, Zn, Fe and Ti) detected in the mucus from the surface of the hypertrophic tissues resembled the particles found in the hypertrophic tissue itself. It can be assumed that after the capture of the inhaled particles by the mucus, they penetrate into the deeper layers of tissue.
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http://dx.doi.org/10.1007/s11356-020-09156-7DOI Listing
August 2020

Chlorophyll Content in Two Medicinal Plant Species Following Nano-TiO Exposure.

Bull Environ Contam Toxicol 2020 Mar 18;104(3):373-379. Epub 2020 Jan 18.

Frank Laboratory of Neutron Physics, Joint Institute of Nuclear Research, Dubna, Russia.

Chlorophyll content in leaves is a convenient indicator of the physiological state of the plant following exposure to a stressor. In the present study, a pot experiment was carried out using two medicinal plant species - peppermint (Mentha X piperita L.) and common sage (Salvia officinalis L.) to determine the link between the chlorophyll content in the plant leaves and the exposure of the plants to nano-TiO either through the leaves (in suspension) or through the root system (in soil). Following the exposure, the shoots were analysed for the contents of Ti, Al, Ca, K, Mg, Mn, Na and chlorophyll. Significant decrease in chlorophyll content was observed in all but one of the nano-TiO treatments, the differences in the determined element content were mostly species-dependent: Ti exposure was found to be related to the decrease in the chlorophyll and Mn content in both species as well as to the decrease in Mg content in common sage.
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http://dx.doi.org/10.1007/s00128-020-02787-zDOI Listing
March 2020

The role of metabolic syndrome in the induction of chronic pancreatitis after a first attack of acute pancreatitis - multicenter trial.

Vnitr Lek 2020 ;66(8):12-16

Background: Metabolic syndrome is a serious societal problem worldwide. In the Czech Republic more than 30% of the adult population are sufferers. The role of recurrent acute pancreatitis in the induction of chronic pancreatitis, following the socalled „mechanistic definition“ of chronic pancreatitis, has been unequivocally confirmed. However, there are a number of factors that may contribute to the development of chronic pancreatitis. The first aim of the study was to determine whether the metabolic syndrome may affect the development of chronic pancreatitis. The second question we asked ourselves was whether even one acute attack of pancreatitis could be an inductive factor in chronic pancreatitis.

Methods: Based on data obtained retrospectively from a total of 264 people diagnosed with chronic pancreatitis in 4 centers, a total of 59 people (22.3%) diagnosed within 36 months of a first attack of acute pancreatitis was obtained. Etiologies of either genetically induced pancreatitis or autoimmune pancreatitis were excluded. Diagnostics to identify the presence of metabolic syndrome were run on the 59 persons so obtained using the criteria from the socalled „harmonized“ definition of 2009 (obesity, arterial hypertension, hypertriglyceridemia, type 2 diabetes mellitus and a decreased level of HDL cholesterol).

Results: Comparing the findings of the individual components of metabolic syndrome in persons with chronic pancreatitis after a 1st attack of acute pancreatitis with the metabolic syndrome and in persons with chronic pancreatitis after the 1st attack of acute pancreatitis but without metabolic syndrome, a statistically significant difference in obesity was found (82.5% vs. 28.5%), hypertriglyceridemia (82.3% vs 17.8%) and arterial hypertension (70.5% vs 21.4%). The interval during which chronic pancreatitis occurred after acute pancreatitis averaged 12 months (10-14 months) in subjects with metabolic syndrome, whereas in the group without metabolic syndrome the interval was longer, 20 months (16-29 months).

Conclusion: Our results show that even one attack of acute pancreatitis (regardless of etiology) can be an inductive factor in chronic pancreatitis. The presence of metabolic syndrome can accelerate the development of chronic pancreatitis after one has had acute pancreatitis.
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March 2021

Cardiac papillary fibroelastomas: A 10-year single-center surgical experience and long-term echocardiographic follow-up study.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2020 Mar 18;164(1):84-91. Epub 2019 Nov 18.

Department of Cardiac Surgery, University Hospital Ostrava, Ostrava, Czech Republic.

Aims: Limited contemporary data are available on the clinical and echocardiographic outcomes after surgery for cardiac papillary fibroelastoma (CPF). The aim of this study was to review the clinical manifestations, pathological characteristics, surgical management, and prognoses of patients with histologically verified CPF, who underwent surgery at our cardiac surgery center from 2008 to 2018.

Methods And Results: Twelve patients of median age 62 years (28 to 77 years) were treated. Embolic stroke or transient ischemic attack (five patients, 42%) were the only CPF clinical manifestations. Eleven (92%) tumors were localized on the valves, with the aortic valve being the most common tumor site (seven patients; 58%). Multiple factor analysis revealed no independent predictor of CPF-related embolization. Simple shave tumor excision was sufficient in most patients (10 patients, 83%). No operative or tumor-related late mortality during the median follow-up period of 4.7 years (1.1 to 10.2 years) was recorded. Asymptomatic metachronous valve tumor recurrence (in a location different from that of the original tumor) was revealed in two patients (17%) by transesophageal echocardiography (TEE), not detected by transthoracic echocardiography (TTE). One of these two patients underwent repeated surgery for CPF but later suffered a recurrent embolic stroke, due to another tumor recurrence.

Conclusion: CPF can be safely and effectively treated surgically. TEE is superior to the TTE option in CPF post-operative recurrence detection. There is a clear need for a prospective study to determine criteria for embolization risk stratification and optimum management in patients with CPF.
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http://dx.doi.org/10.5507/bp.2019.053DOI Listing
March 2020

Immunohistochemical analysis of retraction pocket pars tensa of tympanic membrane in children.

Int J Pediatr Otorhinolaryngol 2019 Jul 11;122:111-116. Epub 2019 Apr 11.

Department of Pediatrics, University Hospital Brno and Faculty of Medicine, Masaryk University Brno, Brno, Czech Republic.

Aims: Immunohistochemical analysis of retraction pocket pars tensa of tympanic membrane in children. Identification of signs typical for cholesteatoma and support of retraction theory of cholesteatoma.

Study Design: a prospective study analysing 31 surgically removed retraction pockets.

Department: University Hospital, Children's Medical Centre Methods: Retraction pockets processed by a standard process for immunohistochemical analysis. The observed findings were specified using antibodies CD45 LCA (leukocyte common antigen), CD31 (platelet endothelial cell adhesion molecule), D2-40 (marker of lymphatic endothelium), MMP9 (marker of degradation of connective tissue extracellular matrix) and Ki67 (cellular marker of proliferation).

Results: All observed parameters except for MMP9 had a significantly higher incidence in retraction pocket stage III compared to stage II according to Charachon.

Conclusion: We described immunohistochemical signs of retraction pocket pars tensa of tympanic membrane in children resulting in cholesteatoma. All the observed signs occur in the structure of matrix and perimatrix of cholesteatoma. A significantly higher incidence of all observed parameters except from MMP9 was proved in retraction pocket stage III, unlike in stage II. This observation proves the fact that retraction pocket is a progressive disease and is a procholesteatoma stage.
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http://dx.doi.org/10.1016/j.ijporl.2019.04.008DOI Listing
July 2019

Ti and Zn Content in Moss Shoots After Exposure to TiO and ZnO Nanoparticles: Biomonitoring Possibilities.

Bull Environ Contam Toxicol 2019 Feb 17;102(2):218-223. Epub 2019 Jan 17.

Nanotechnology Centre, VŠB-Technical University of Ostrava, 17. listopadu 15/2172, 708 33, Ostrava, Czech Republic.

To assess the uptake of nanoparticles by moss shoots and the possibility of biomonitoring the moss of nanoparticle pollution, two moss species frequently used in biomonitoring surveys [Hylocomium splendens (Hedw.) Schimp. and Pleurozium schreberi (Brid.) Mitt.] were repeatedly exposed to known concentrations of either nano-TiO or nano-ZnO suspensions. The interspecies differences were assessed by exposing both the species to 1 g L nano-ZnO suspension, H. splendens samples were also exposed to either 0.1 g L or 1 g L suspension of nano TiO. The exposed samples were analysed for Zn or Ti content using Inductively Coupled Plasma-Atomic Emission Spectroscopy. Both species showed a similar accumulation pattern, H. splendens being a slightly better accumulator. The washing suggests that Ti successfully penetrated the interior of the gametophyte. Since the relationship between the exposure and accumulation is linear, moss biomonitoring is, hereby, considered to be a viable, novel technique in nanoparticle pollution assessment.
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http://dx.doi.org/10.1007/s00128-019-02544-xDOI Listing
February 2019

Effects of binder choice in converter and blast furnace sludge briquette preparation: Environmental and practical implications.

Waste Manag 2018 Sep 17;79:30-37. Epub 2018 Jul 17.

Nanotechnology Centre, VŠB-Technical University of Ostrava, 17. listopadu 15/2172, 708 33 Ostrava-Poruba, Czech Republic.

Blast furnace and converter sludges are fine-grained waste materials characterized as dangerous waste with a negative impact on the environment. One way of recycling of such materials is briquetting followed by reuse of the material in the blast furnace. In the briquetting process, an important step is the choice of the binder suitable for manufacturing the briquettes with suitable mechanical properties. In this work, the effect of the binder choice (laundry starch UNIPRET, Portland cement) on the reduction of iron oxides in the assessed waste materials during thermal treatment (900, 1000, 1100 °C) is evaluated. Simultaneously, the effect of the binder choice on the amount and composition of the resulting waste gas was evaluated as well as its possible impact on the environment. The performed experiments proved the mutual relationship between the level of iron oxides to metal iron conversion, the binder content and retention temperature. Type of binder also affected the volume of the resulting waste gas. Factor analysis for mixed data (FAMD) proved that the resulting concentrations of the assessed hydrocarbons were correlated (apart from ethyne) and that they are closely associated with the binder applied. Conversely, the concentrations of ethyne, carbon monoxide and carbon dioxide were not associated with the binder but with the retention temperature. FAMD did not show any direct effect of final retention temperature on the amount of the rest of the resulting hydrocarbons. In comparison with the starch-containing briquettes, the cement-containing briquettes were also proved to lead to lower resulting concentrations of PAHs in the waste gas.
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http://dx.doi.org/10.1016/j.wasman.2018.06.051DOI Listing
September 2018

Crohn's disease - genetic factors and progress of the disease.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2018 Jun 18;162(2):139-143. Epub 2018 Jan 18.

Department of Internal Medicine, University Hospital Ostrava, Czech Republic.

Background And Objectives: Crohn's disease is a multifactorial inflammatory disease affecting mainly the gastrointestinal tract. The genetic factors that are involved in the disease include mainly three mutations of the gene NOD2/CARD15 (R702W, G908R, 3020insC). The aim of this study was to determine the relationship between the presence of these variants and disease phenotype.

Material And Methods: 70 patients with Crohn's disease were examined for the presence of the above-mentioned mutations. The researchers used the medical records to retrospectively obtain clinical data and together with the information obtained prospectively according to the protocol they analysed the connection between gene mutations and disease phenotype.

Results: At least one mutation was found in 22 patients with Crohn's disease (32%), four patients were found to have two different mutations (composed heterozygotes - 6%) and six patients (9%) were homozygotes for the 3020insC gene. No significant differences were found between the groups with wild-type form and the mutated form of the NOD2 / CARD15 gene with respect to age at the time of diagnosis, form of the disease or localization according to the Montreal classification.

Conclusion: Mutations of the NOD2 / CARD15 gene did not significantly affect the frequency of reoperations, homozygotes with 3020insC gene mutations, however, represented a high risk group. The phenotype was not related significantly to the presence of the examined mutations.
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http://dx.doi.org/10.5507/bp.2017.058DOI Listing
June 2018

Low intrapatient variability of histomorphological findings in periprosthetic tissues from revised metal/ceramic on polyethylene joint arthroplasties.

J Biomed Mater Res B Appl Biomater 2018 07 16;106(5):2008-2018. Epub 2017 Oct 16.

Department of Pathology, University Hospital Ostrava, Ostrava-Poruba, 708 52, Czech Republic.

The type of tissue response to implant by-products can be determined by examination of periprosthetic tissues. However, little is known about the most suitable location for tissue sampling. The main goal of this study was to evaluate the extent of variability in tissue response in relation to location of tissue sampling, implant fixation, age and sex in total joint arthroplasties with metal-on-polyethylene or ceramic-on-polyethylene bearing pairs. We processed 236 histology slides from 21 patients and focused on the association between the location of tissue samples and histological features. The presence of the synovial hyperplasia showed a significant association with the particular sampling site. A higher density of high endothelial cell venules was seen in the samples from around the joint, and polyethylene particles were more abundant in noncemented TJA but both findings did not show statistically significant association with the sampling site. The results showed a relatively small variance in the tissue response to prosthetic by-products among tissues sampled from the same patient. Our findings indicate that tissue samples retrieved from similar distance from around the TJA during the revision operation show comparable results of histological analysis. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 2008-2018, 2018.
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http://dx.doi.org/10.1002/jbm.b.33990DOI Listing
July 2018

PAH emissions from old and new types of domestic hot water boilers.

Environ Pollut 2017 Jun 26;225:31-39. Epub 2017 Mar 26.

Nanotechnology Centre, VSB-Technical University of Ostrava, 17. listopadu 15/2172, 708 33 Ostrava, Poruba, Czech Republic; Centre Energy Units for Utilization of Non Traditional Energy Sources, VSB-Technical University of Ostrava, 17. listopadu 15/2172, 708 33 Ostrava, Poruba, Czech Republic.

Five different domestic heating boilers (automatic, over-fire, with down-draft combustion and gasification) and three types of fuel (lignite, wood and mixed fuel) were examined in 25 combustion tests and correlated with the emissions of particulate matter (PM), carbon monoxide (CO), total organic carbon (TOC) and 12 polycyclic aromatic hydrocarbons (PAHs with MW = 178-278 g/mol) focusing on particle phase. However, the distribution of 12 PAHs in gas phase was considered as well due to the presence mainly of lighter PAHs in gas phase. The PAHs, as well as the CO and TOC, are the indicators of incomplete combustion, and in this study PAH emission increased significantly with increasing emissions of CO and TOC. The PAHs were mainly detected on PM, their contents were increasing linearly with increasing PM emissions. The highest emission factors of PAHs were measured for boilers of old construction, such as over-fire boiler (5.8-929 mg/kg) and boiler with down-draft combustion (3.1-54.1 mg/kg). Modern types of boilers produced much lower emissions of PAHs, in particular, automatic boiler (0.3-3.3 mg/kg) and gasification boilers (0.2-6.7 mg/kg). In general, the inefficient combustion at reduced output of boilers generated 1.4-17.7 times more emissions of PAHs than the combustion at nominal output of boilers. It is recommended to operate boilers at nominal output with sufficient air supply and to use the proper fuel to minimise PAHs emissions from domestic heating appliances.
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http://dx.doi.org/10.1016/j.envpol.2017.03.034DOI Listing
June 2017

Recycling of blast furnace sludge by briquetting with starch binder: Waste gas from thermal treatment utilizable as a fuel.

Waste Manag 2016 Feb 9;48:471-477. Epub 2015 Dec 9.

VŠB-Technical University of Ostrava, Nanotechnology Centre, 17. listopadu 15/2172, 708 33 Ostrava-Poruba, Czech Republic.

Steel plants generate significant amounts of wastes such as sludge, slag, and dust. Blast furnace sludge is a fine-grained waste characterized as hazardous and affecting the environment negatively. Briquetting is one of the possible ways of recycling of this waste while the formed briquettes serve as a feed material to the blast furnace. Several binders, both organic and inorganic, had been assessed, however, only the solid product had been analysed. The aim of this study was to assess the possibilities of briquetting using commonly available laundry starch as a binder while evaluating the possible utilization of the waste gas originating from the thermal treatment of the briquettes. Briquettes (100g) were formed with the admixture of starch (UNIPRET) and their mechanical properties were analysed. Consequently, they were subjected to thermal treatment of 900, 1000 and 1100°C with retention period of 40min during which was the waste gas collected and its content analysed using gas chromatography. Dependency of the concentration of the compounds forming the waste gas on the temperature used was determined using Principal component analysis (PCA) and correlation matrix. Starch was found to be a very good binder and reduction agent, it was confirmed that metallic iron was formed during the thermal treatment. Approximately 20l of waste gas was obtained from the treatment of one briquette; main compounds were methane and hydrogen rendering the waste gas utilizable as a fuel while the greatest yield was during the lowest temperatures. Preparation of blast furnace sludge briquettes using starch as a binder and their thermal treatment represents a suitable method for recycling of this type of metallurgical waste. Moreover, the composition of the resulting gas is favourable for its use as a fuel.
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http://dx.doi.org/10.1016/j.wasman.2015.11.047DOI Listing
February 2016

Lymphangiogenesis and its correlation with the VEGF expression and the sentinel lymph node in cutaneous melanomas.

Biomed Res Int 2014 25;2014:372979. Epub 2014 Jun 25.

Center of Nanotechnology, VSB-Technical University, Ostrava, Czech Republic.

The aim of the study is to evaluate the density of intratumoral and peritumoral lymphatic vessels in primary cutaneous melanomas and to assess their correlation with the status of sentinel lymph nodes and the VEGF expression in tumor cells and stromal cells. A total of 40 patients were enrolled in the study: the melanomas were radically excised with the extirpation of the sentinel lymph node. The study subjects were divided into two groups: 20 cases with positive and 20 cases with negative sentinel lymph node results. The density of lymphatic vessels was evaluated by the antibody D2-40 and the VEGF expression was investigated in the semiquantitative way. The VEGF expression in melanoma cells and the stromal cells was negative to variable positive at both SLN negative and SLN positive patients in all pT stages. In the group of SLN positive patients, the density of intratumoral lymphatic vessels was low up to moderate, while it was observed to be absent, somewhere on the low level in the group of SLN negative patients. On the other side, the density of peritumoral lymphatic vessels was equally numerous at both SLN negative and SLN positive patients. The lymphatic invasion was found out at 4 SLN positive patients only. The ulceration was chiefly in the group of LN positive patients. The results show that the density of lymphangiogenesis and the intensity of the VEGF expression are considered to be an unreliable predictor of melanoma metastasis to the sentinel lymph node, but the ulceration and the lymphatic invasion can predict the potential for metastasis.
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http://dx.doi.org/10.1155/2014/372979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096056PMC
October 2015

Myocardial revascularisation in patients with severe left ventricular dysfunction. Early and midterm results.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2004 Jul;148(1):55-8

Department of Cardiac Surgery, University Hospital Ostrava, Czech Republic.

Aims: This retrospective study evaluates early and midterm results in patients with severe left ventricular dysfunction.

Technique: Ninety-seven consecutive patients with coronary artery disease and ejection fraction of left ventricle (LVEF) less or equal to 25 % underwent elective coronary artery bypass graft procedure between September 1998 and December 2001. Mean age at operation was 66 (47-86) years. The main symptoms were angina class III-IV Canadian Cardiovascular Society (CCS) in 78 patients (80 %) and dyspnoea class III-IV New York Heart Association (NYHA) in 43 patients (44 %). The major indications for surgery were severe angina, dyspnoea in 90 patients (93 %). Cardiac index (CI), echocardiography (ECHO), planimetry, end-diastolic pressure of left ventricle (LVEDP), end-diastolic diameter of left ventricle (LVEDd) were used to access left ventricular function preoperatively. ECHO was also used to access left ventricular function postoperatively.

Results: Early postoperative (30 days) mortality was 4.1 %. Complications had 25 patients (26 %) postoperatively. Two years survival was 95.7 %. Class III-IV CCS and/or NYHA had 17 patients (17.5 %) two years after surgery. LVEF (assessed by ECHO) improved from 23.1 % preoperatively to 36.0 % postoperatively (p < 0.05).

Conclusion: The study showed that elective myocardial revascularisation in patients with severe left ventricular dysfunction and signs of myocardial viability is not necessarily associated with high operative mortality. It can be performed safely with respectable midterm survival in concordance with left ventricular function improvement, symptom relief and quality of life improvement.
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http://dx.doi.org/10.5507/bp.2004.009DOI Listing
July 2004