Olaf Sommerburg

Effects of Lumacaftor-Ivacaftor on Lung Clearance Index, Magnetic Resonance Imaging and Airway Microbiome in Phe508del Homozygous Patients with Cystic Fibrosis.

Authors:

Simon Y Graeber Sébastien Boutin Mark O Wielpütz Cornelia Joachim Dario L Frey Sabine Wege Olaf Sommerburg Hans-Ulrich Kauczor Mirjam Stahl Alexander H Dalpke Marcus A Mall

Ann Am Thorac Soc 2021 Feb 18. Epub 2021 Feb 18.

Charité Universitätsmedizin Berlin, 14903, Department of Pediatric Pulmonology, Immunology and Critical Care Medicine and Cystic Fibrosis Center, Berlin, Berlin, Germany.

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February 2021

Pancreatitis-Associated Protein in Neonatal Screening for Cystic Fibrosis: Strengths and Weaknesses.

Authors:

Olaf Sommerburg Jutta Hammermann

Int J Neonatal Screen 2020 Mar 30;6(2). Epub 2020 Mar 30.

Pediatric Department, University Hospital of Dresden, Fetscherstr. 74, D-01307 Dresden, Germany.

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March 2020

Relationship between airway dysbiosis, inflammation and lung function in adults with cystic fibrosis.

Authors:

Dario L Frey Sébastien Boutin Susanne A Dittrich Simon Y Graeber Mirjam Stahl Sabine Wege Felix J F Herth Olaf Sommerburg Carsten Schultz Marcus A Mall Alexander H Dalpke

J Cyst Fibros 2021 Jan 8. Epub 2021 Jan 8.

Translational Lung Research Center (TLRC), Heidelberg, Germany; Department of Infectious Diseases, Medical Microbiology and Hygiene, University of Heidelberg, Heidelberg, Germany; Institute of Medical Microbiology and Hygiene, Technische Universität Dresden, Dresden, Germany.

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January 2021

Multicentre feasibility of multiple-breath washout in preschool children with cystic fibrosis and other lung diseases.

ERJ Open Res 2020 Oct 26;6(4). Epub 2020 Oct 26.

Dept of Pediatric Pulmonology, Immunology and Critical Care Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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October 2020

Updated guidance on the management of children with cystic fibrosis transmembrane conductance regulator-related metabolic syndrome/cystic fibrosis screen positive, inconclusive diagnosis (CRMS/CFSPID).

Authors:

Jürg Barben Carlo Castellani Anne Munck Jane C Davies Karin M de Winter-de Groot Silvia Gartner Nataliya Kashirskaya Barry Linnane Sarah J Mayell Susanna McColley Chee Y Ooi Marijke Proesmans Clement L Ren Danieli Salinas Dorota Sands Isabelle Sermet-Gaudelus Olaf Sommerburg Kevin W Southern

J Cyst Fibros 2020 Nov 27. Epub 2020 Nov 27.

Department of Women's and Children's Health, University of Liverpool, UK.

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November 2020

Implementing a tracking system for confirmatory diagnostic results after positive newborn screening for cystic fibrosis-implications for process quality and patient care.

Authors:

Gwendolyn Gramer Inken Brockow Christiane Labitzke Junmin Fang-Hoffmann Andreas Beivers Patrik Feyh Georg F Hoffmann Uta Nennstiel Olaf Sommerburg

Eur J Pediatr 2020 Oct 26. Epub 2020 Oct 26.

Translational Lung Research Center (TLRC), German Lung Research Center (DZL), University of Heidelberg, Heidelberg, Germany.

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October 2020

Pancreatitis-Associated Protein in Neonatal Screening for Cystic Fibrosis: Strengths and Weaknesses.

Authors:

Olaf Sommerburg Jutta Hammermann

Int J Neonatal Screen 2020 Jun 30;6(2):28. Epub 2020 Mar 30.

Pediatric Department, University Hospital of Dresden, Fetscherstr. 74, D-01307 Dresden, Germany;

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June 2020

Rescue of respiratory failure in pulmonary alveolar proteinosis due to pathogenic MARS1 variants.

Authors:

Dominic Lenz Mirjam Stahl Elias Seidl Dominik Schöndorf Heiko Brennenstuhl Florian Gesenhues Tina Heinzmann Thomas Longerich Marisa I Mendes Holger Prokisch Gajja S Salomons Carola Schön Desirée E C Smith Olaf Sommerburg Matias Wagner Jens H Westhoff Karl Reiter Christian Staufner Matthias Griese

Pediatr Pulmonol 2020 11 7;55(11):3057-3066. Epub 2020 Sep 7.

Dr. von Haunersches Kinderspital, University of Munich, German Center for Lung Research (DZL), Munich, Germany.

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November 2020

[Abdominal manifestations in cystic fibrosis : Clinical review].

Authors:

Olaf Sommerburg Jens-Peter Schenk

Radiologe 2020 Sep;60(9):781-790

Sektion für Pädiatrische Radiologie, Klinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.

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September 2020

Echo Time-Dependence of Observed Lung T in Patients With Cystic Fibrosis and Correlation With Clinical Metrics.

Authors:

Simon M F Triphan Mirjam Stahl Bertram J Jobst Olaf Sommerburg Hans-Ulrich Kauczor Jens-Peter Schenk Abdulsattar Alrajab Monika Eichinger Marcus A Mall Mark O Wielpütz

J Magn Reson Imaging 2020 12 2;52(6):1645-1654. Epub 2020 Jul 2.

Department of Diagnostic and Interventional Radiology, University of Heidelberg, Heidelberg, Germany.

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December 2020

The value of chest magnetic resonance imaging compared to chest radiographs with and without additional lung ultrasound in children with complicated pneumonia.

Authors:

Philip Konietzke Jan Mueller Felix Wuennemann Willi L Wagner Jens-Peter Schenk Abdulsattar Alrajab Hans-Ulrich Kauczor Mirjam Stahl Marcus A Mall Mark O Wielpütz Olaf Sommerburg

PLoS One 2020 19;15(3):e0230252. Epub 2020 Mar 19.

Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.

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June 2020

Magnetic Resonance Imaging Detects Chronic Rhinosinusitis in Infants and Preschool Children with Cystic Fibrosis.

Authors:

Olaf Sommerburg Mark O Wielpütz Jan-Philipp Trame Felix Wuennemann Elzbieta Opdazaite Mirjam Stahl Michael U Puderbach Annette Kopp-Schneider Eva Fritzsching Hans-Ulrich Kauczor Ingo Baumann Marcus A Mall Monika Eichinger

Ann Am Thorac Soc 2020 06;17(6):714-723

Translational Lung Research Center, German Lung Research Center.

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June 2020

Risk Factors for Complicated Lymphadenitis Caused by Nontuberculous Mycobacteria in Children.

Emerg Infect Dis 2020 03;26(3):579-586

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March 2020

Ten years of chest MRI for patients with cystic fibrosis : Translation from the bench to clinical routine.

Authors:

Patricia Leutz-Schmidt Monika Eichinger Mirjam Stahl Olaf Sommerburg Jürgen Biederer Hans-Ulrich Kauczor Michael U Puderbach Marcus A Mall Mark O Wielpütz

Radiologe 2019 Dec;59(Suppl 1):10-20

Department of Diagnostic and Interventional Radiology, Subdivision Pulmonary Imaging, University Hospital of Heidelberg, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

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December 2019

Preventive Inhalation of Hypertonic Saline in Infants with Cystic Fibrosis (PRESIS). A Randomized, Double-Blind, Controlled Study.

Authors:

Mirjam Stahl Mark O Wielpütz Isabell Ricklefs Christian Dopfer Sandra Barth Anne Schlegtendal Simon Y Graeber Olaf Sommerburg Gesa Diekmann Johannes Hüsing Cordula Koerner-Rettberg Lutz Nährlich Anna-Maria Dittrich Matthias V Kopp Marcus A Mall

Am J Respir Crit Care Med 2019 05;199(10):1238-1248

1 Department of Translational Pulmonology.

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May 2019

Non-contrast enhanced magnetic resonance imaging detects mosaic signal intensity in early cystic fibrosis lung disease.

Authors:

Patricia Leutz-Schmidt Mirjam Stahl Olaf Sommerburg Monika Eichinger Michael U Puderbach Jens-Peter Schenk Abdulsattar Alrajab Simon M F Triphan Hans-Ulrich Kauczor Marcus A Mall Mark O Wielpütz

Eur J Radiol 2018 Apr 21;101:178-183. Epub 2018 Feb 21.

Department of Diagnostic and Interventional Radiology, University of Heidelberg, Heidelberg, Germany; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at University of Heidelberg, Heidelberg, Germany; Department of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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April 2018

[Newborn Screening on Cystic Fibrosis in Germany: Comparison of the new Screening Protocol with an Alternative Protocol].

Authors:

Olaf Sommerburg Mirjam Stahl Jutta Hammermann Jürgen G Okun Andreas Kulozik Georg Hoffmann Marcus Mall

Klin Padiatr 2017 Mar 25;229(2):59-66. Epub 2017 Apr 25.

Sektion für Pädiatrische Pneumologie & Allergologie und Mukoviszidose-Zentrum, Zentrum für Kinder- und Jugendmedizin, Universitätsklinikum Heidelberg.

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March 2017

Diagnosis of Cystic Fibrosis in Screened Populations.

Authors:

Philip M Farrell Terry B White Michelle S Howenstine Anne Munck Richard B Parad Margaret Rosenfeld Olaf Sommerburg Frank J Accurso Jane C Davies Michael J Rock Don B Sanders Michael Wilschanski Isabelle Sermet-Gaudelus Hannah Blau Silvia Gartner Susanna A McColley

J Pediatr 2017 02;181S:S33-S44.e2

Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL.

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February 2017

The expansion and performance of national newborn screening programmes for cystic fibrosis in Europe.

Authors:

Jürg Barben Carlo Castellani Jeannette Dankert-Roelse Silvia Gartner Nataliya Kashirskaya Barry Linnane Sarah Mayell Anne Munck Dorota Sands Olaf Sommerburg Simon Pybus Victoria Winters Kevin W Southern

J Cyst Fibros 2017 Mar 30;16(2):207-213. Epub 2016 Dec 30.

Institute in the Park, Alder Hey Children's Hospital, University of Liverpool, UK.

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March 2017

Early detection and sensitive monitoring of CF lung disease: Prospects of improved and safer imaging.

Authors:

Marcus A Mall Mirjam Stahl Simon Y Graeber Olaf Sommerburg Hans-Ulrich Kauczor Mark O Wielpütz

Pediatr Pulmonol 2016 Oct;51(S44):S49-S60

Translational Lung Research Center Heidelberg (TLRC), Member of the German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.

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October 2016

Comparison of Lung Clearance Index and Magnetic Resonance Imaging for Assessment of Lung Disease in Children with Cystic Fibrosis.

Authors:

Mirjam Stahl Mark O Wielpütz Simon Y Graeber Cornelia Joachim Olaf Sommerburg Hans-Ulrich Kauczor Michael Puderbach Monika Eichinger Marcus A Mall

Am J Respir Crit Care Med 2017 02;195(3):349-359

1 Department of Translational Pulmonology.

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February 2017

A product of immunoreactive trypsinogen and pancreatitis-associated protein as second-tier strategy in cystic fibrosis newborn screening.

Authors:

Sophia Weidler Konrad H Stopsack Jutta Hammermann Olaf Sommerburg Marcus A Mall Georg F Hoffmann Dirk Kohlmüller Jürgen G Okun Milan Macek Felix Votava Veronika Krulišová Miroslava Balaščaková Veronika Skalická Min Ae Lee-Kirsch Marina Stopsack

J Cyst Fibros 2016 11 22;15(6):752-758. Epub 2016 Jul 22.

Institute of Clinical Chemistry and Laboratory Medicine, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307 Dresden, Germany. Electronic address:

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November 2016

Multiple prevalent fractures in relation to macroscopic bone architecture in patients with cystic fibrosis.

Authors:

Mirjam Stahl Christian Holfelder Carolin Kneppo Meinhard Kieser Christian Kasperk Eckhard Schoenau Olaf Sommerburg Burkhard Tönshoff

J Cyst Fibros 2018 01 18;17(1):114-120. Epub 2016 Jun 18.

Department of Pediatrics I, University Children's Hospital Heidelberg, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany.

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January 2018

Sino nasal inhalation of isotonic versus hypertonic saline (6.0%) in CF patients with chronic rhinosinusitis - Results of a multicenter, prospective, randomized, double-blind, controlled trial.

Authors:

Jochen G Mainz Ulrike Schumacher Katja Schädlich Julia Hentschel Christiane Koitschev Assen Koitschev Joachim Riethmüller Freerk Prenzel Olaf Sommerburg Bärbel Wiedemann Doris Staab Wolfgang Gleiber Rainald Fischer James F Beck Christin Arnold

J Cyst Fibros 2016 11 5;15(6):e57-e66. Epub 2016 Jun 5.

Jena University Hospital, CF Centre, Jena, Germany. Electronic address:

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November 2016

Toward quality improvement in cystic fibrosis newborn screening: Progress and continuing challenges.

Authors:

Philip M Farrell Olaf Sommerburg

J Cyst Fibros 2016 05 10;15(3):267-9. Epub 2016 May 10.

Division of Pediatric Pulmonology & Allergology, University Children's Hospital III & Translational Lung Research Center Heidelberg (TLRC), Member of the German Center for Lung Research (DZL), Im Neuenheimer Feld 350, D-69120 Heidelberg, Germany.

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May 2016

Intestinal Current Measurements Detect Activation of Mutant CFTR in Patients with Cystic Fibrosis with the G551D Mutation Treated with Ivacaftor.

Authors:

Simon Y Graeber Martin J Hug Olaf Sommerburg Stephanie Hirtz Julia Hentschel Andrea Heinzmann Christian Dopfer Angela Schulz Jochen G Mainz Burkhard Tümmler Marcus A Mall

Am J Respir Crit Care Med 2015 Nov;192(10):1252-5

1 University of Heidelberg Heidelberg, Germany.

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November 2015

Five years of experience with biochemical cystic fibrosis newborn screening based on IRT/PAP in Germany.

Authors:

Olaf Sommerburg Jutta Hammermann Martin Lindner Mirjam Stahl Martina Muckenthaler Dirk Kohlmueller Margit Happich Andreas E Kulozik Marina Stopsack Manfred Gahr Georg F Hoffmann Marcus A Mall

Pediatr Pulmonol 2015 Jul 23;50(7):655-64. Epub 2015 Apr 23.

Division of Pediatric Pulmonology & Allergy and Cystic Fibrosis Center, Department of Pediatrics III, University of Heidelberg, Im Neuenheimer Feld 430, D-69120, Heidelberg, Germany.

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July 2015

Supplementation with red palm oil increases β-carotene and vitamin A blood levels in patients with cystic fibrosis.

Authors:

Olaf Sommerburg Silke De Spirt Annett Mattern Cornelia Joachim Claus-Dieter Langhans Kalanithi Nesaretnam Werner Siems Wilhelm Stahl Marcus A Mall

Mediators Inflamm 2015 26;2015:817127. Epub 2015 Jan 26.

Division of Pediatric Pulmonology & Allergy and Cystic Fibrosis Centre, Department of Pediatrics III, Children's Hospital, University of Heidelberg, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany ; Translational Lung Research Centre Heidelberg (TLRC), Member of the German Centre for Lung Research (DZL), Im Neuenheimer Feld 350, 69120 Heidelberg, Germany ; Department of Translational Pulmonology, University of Heidelberg, Im Neuenheimer Feld 350, 69120 Heidelberg, Germany.

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January 2016

Airway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema.

Authors:

Joanna B Trojanek Amanda Cobos-Correa Stefanie Diemer Michael Kormann Susanne C Schubert Zhe Zhou-Suckow Raman Agrawal Julia Duerr Claudius J Wagner Jolanthe Schatterny Stephanie Hirtz Olaf Sommerburg Dominik Hartl Carsten Schultz Marcus A Mall

Am J Respir Cell Mol Biol 2014 Nov;51(5):709-20

1 Department of Translational Pulmonology, and.

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November 2014

Magnetic resonance imaging detects changes in structure and perfusion, and response to therapy in early cystic fibrosis lung disease.

Authors:

Mark O Wielpütz Michael Puderbach Annette Kopp-Schneider Mirjam Stahl Eva Fritzsching Olaf Sommerburg Sebastian Ley Migle Sumkauskaite Jürgen Biederer Hans-Ulrich Kauczor Monika Eichinger Marcus A Mall

Am J Respir Crit Care Med 2014 Apr;189(8):956-65

1 Department of Diagnostic and Interventional Radiology.

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April 2014

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