Publications by authors named "Olaf Heidenreich"

53Publications

t(8;21) Acute Myeloid Leukemia as a Paradigm for the Understanding of Leukemogenesis at the Level of Gene Regulation and Chromatin Programming.

Cells 2020 12 13;9(12). Epub 2020 Dec 13.

Princess Máxima Centrum for Pediatric Oncology, Heidelberglaan 25, 3584CS Utrecht, The Netherlands.

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December 2020

The RUNX1/RUNX1T1 network: translating insights into therapeutic options.

Exp Hematol 2020 Nov 17. Epub 2020 Nov 17.

Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands. Electronic address:

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November 2020

Epidemiology and biology of relapse after stem cell transplantation.

Bone Marrow Transplant 2018 11 18;53(11):1379-1389. Epub 2018 Apr 18.

Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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November 2018

Dormancy Stems the Tide of Chemotherapy.

Cancer Cell 2016 Dec;30(6):825-826

Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Level 6, Herschel Building, Brewery Lane, Newcastle upon Tyne NE1 7RU, UK. Electronic address:

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December 2016

The ability to cross the blood-cerebrospinal fluid barrier is a generic property of acute lymphoblastic leukemia blasts.

Blood 2016 Apr 11;127(16):1998-2006. Epub 2016 Feb 11.

Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary, and Life Sciences, University of Glasgow, Glasgow, United Kingdom; and Department of Paediatric Haematology, Royal Hospital for Children, Glasgow, United Kingdom.

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April 2016

Gene Silencing by RNAi in Mammalian Cells.

Curr Protoc Mol Biol 2015 Jul 1;111:26.2.1-26.2.17. Epub 2015 Jul 1.

Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.

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July 2015

CD19: A multifunctional immunological target molecule and its implications for Blineage acute lymphoblastic leukemia.

Pediatr Blood Cancer 2015 Jul 8;62(7):1144-8. Epub 2015 Mar 8.

Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, UK.

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July 2015

Development of a preclinical orthotopic xenograft model of ewing sarcoma and other human malignant bone disease using advanced in vivo imaging.

PLoS One 2014 7;9(1):e85128. Epub 2014 Jan 7.

Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom ; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.

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September 2014

Determination of key structure-activity relationships in siRNA delivery with a mixed micelle system.

J Control Release 2013 Dec 18;172(3):939-45. Epub 2013 Oct 18.

Chemical Nanoscience Laboratory, School of Chemistry, Newcastle University, Newcastle upon Tyne, UK.

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December 2013

Molecular parameters of siRNA--cell penetrating peptide nanocomplexes for efficient cellular delivery.

ACS Nano 2013 May 30;7(5):3797-807. Epub 2013 Apr 30.

Department of Biochemistry, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen 6525 GA, The Netherlands.

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May 2013

Acute B lymphoblastic leukaemia-propagating cells are present at high frequency in diverse lymphoblast populations.

EMBO Mol Med 2013 01 11;5(1):38-51. Epub 2012 Dec 11.

Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.

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January 2013

AML1/ETO proteins control POU4F1/BRN3A expression and function in t(8;21) acute myeloid leukemia.

Cancer Res 2010 May 11;70(10):3985-95. Epub 2010 May 11.

Cancer Research UK Medical Oncology Unit, Barts and the London School of Medicine and Dentistry, University of London, London, United Kingdom.

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May 2010

Targeted delivery of SiRNA to CD33-positive tumor cells with liposomal carrier systems.

J Control Release 2010 Jun 22;144(2):251-8. Epub 2010 Feb 22.

Institut für Zellbiologie und Immunologie, Universität Stuttgart, Allmandring 31, 70569 Stuttgart, Germany.

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June 2010

Serum response factor depletion affects the proliferation of the hepatocellular carcinoma cells HepG2 and JHH6.

Biochimie 2010 May 6;92(5):455-63. Epub 2010 Feb 6.

Department of Medical, Technological and Translational Sciences, University Hospital of Cattinara, Trieste, Italy.

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May 2010

Proliferation of human primary vascular smooth muscle cells depends on serum response factor.

Eur J Cell Biol 2010 Feb-Mar;89(2-3):216-24. Epub 2010 Jan 22.

Department of Molecular Biology, Interfaculty Institute for Cell Biology, Eberhard Karls University of Tübingen, Germany.

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June 2010

A Drosophila model identifies calpains as modulators of the human leukemogenic fusion protein AML1-ETO.

Proc Natl Acad Sci U S A 2009 Jul 6;106(29):12043-8. Epub 2009 Jul 6.

Unité Mixte de Recherche 5547, Centre National de Recherche Scientifique, Centre de Biologie du Developpement, Universite de Toulouse, Bat4R3, 1118 route de Narbonne, 31062 Toulouse, France.

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July 2009

Targeting oncogenes with siRNAs.

Authors:
Olaf Heidenreich

Methods Mol Biol 2009 ;487:221-42

Newcastle University, Northern Institute for Cancer Research, Medical School, Newcastle upon Tyne, UK.

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April 2009

Graft protection in bypass surgery: siRNA-mediated silencing of adhesion molecules.

Oligonucleotides 2009 Mar;19(1):15-21

Department of Thoracic, Cardiac, and Vascular Surgery, Tübingen University Hospital, Tübingen, Germany.

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March 2009

Transcriptional upregulation of p21/WAF/Cip1 in myeloid leukemic blasts expressing AML1-ETO.

Haematologica 2008 Nov 11;93(11):1728-33. Epub 2008 Sep 11.

Department of Medicine, Division Hematology/Oncology, University of Freiburg Medical Center, Hugstetter Str. 55, D-79106 Freiburg, Germany.

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November 2008

Gene silencing by RNAi in mammalian cells.

Curr Protoc Mol Biol 2003 May;Chapter 26:Unit 26.2

Ribopharma AG, Kulmbach, Germany.

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May 2003

Inhibition of adhesion molecule expression on human venous endothelial cells by non-viral siRNA transfection.

J Cell Mol Med 2007 Jan-Feb;11(1):139-47

Department of Thoracic, Cardiac and Vascular Surgery, Tuebingen University Hospital, Tuebingen, Germany.

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May 2007

Targeting leukemic fusion proteins with small interfering RNAs: recent advances and therapeutic potentials.

Acta Pharmacol Sin 2006 Mar;27(3):273-81

Department of Molecular Biology, Interfaculty Institute for Cell Biology, Eberhard Karls University Tuebingen, Auf der Morgenstelle 15, 72076 Tuebingen, Germany.

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March 2006

Suppression of ICAM-1 in human venous endothelial cells by small interfering RNAs.

Eur J Cardiothorac Surg 2005 Dec 4;28(6):816-20. Epub 2005 Nov 4.

Department of Thoracic, Cardiac and Vascular Surgery, Tuebingen University Hospital, Hoppe-Seyler-Strasse 3, 72076 Tuebingen, Germany.

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December 2005

Targeting MLL-AF4 with short interfering RNAs inhibits clonogenicity and engraftment of t(4;11)-positive human leukemic cells.

Blood 2005 Nov 26;106(10):3559-66. Epub 2005 Jul 26.

Department of Molecular Biology, Interfaculty Institute for Cell Biology, Eberhard Karls University of Tuebingen, Germany.

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November 2005

RNA interference as a potential tool in the treatment of leukaemia.

Expert Opin Biol Ther 2004 Dec;4(12):1921-9

Dr von Haunersches Kinderspital der Universität München, Abteilung Onkologie und Hämatologie, Germany.

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December 2004

Oncogene suppression by small interfering RNAs.

Authors:
Olaf Heidenreich

Curr Pharm Biotechnol 2004 Aug;5(4):349-54

Department of Molecular Biology, Institute for Cell Biology, Faculty of Biology, Eberhard-Karls University of Tübingen, 72076 Tübingen, Germany.

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August 2004

The apparent uptake of fluorescently labeled siRNAs by electroporated cells depends on the fluorochrome.

Oligonucleotides 2003 ;13(5):375-80

Cancer Research U.K. Medical Oncology Laboratory, Medical College of St. Bartholomew's Hospital, London, U.K.

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April 2004

Specific inhibition of bcr-abl gene expression by small interfering RNA.

Blood 2003 Feb 26;101(4):1566-9. Epub 2002 Sep 26.

Department of Hematology and Oncology, Hannover Medical School, Germany.

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February 2003

Serum response factor is crucial for actin cytoskeletal organization and focal adhesion assembly in embryonic stem cells.

J Cell Biol 2002 Feb 11;156(4):737-50. Epub 2002 Feb 11.

Interfakultäres Institut für Zellbiologie, Abteilung Molekularbiologie, Universität Tübingen, 72076 Tübingen, Germany.

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February 2002