Olaf H Klungel

Olaf H Klungel

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Olaf H Klungel

Publications by authors named "Olaf H Klungel"

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Accuracy of budget impact estimations and impact on patient access: a hepatitis C case study.

Eur J Health Econ 2019 Aug 5;20(6):857-867. Epub 2019 Apr 5.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584CG, Utrecht, The Netherlands.

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http://link.springer.com/10.1007/s10198-019-01048-z
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http://dx.doi.org/10.1007/s10198-019-01048-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652171PMC
August 2019

Risk of myocardial infarction associated with non-steroidal anti-inflammatory drugs: Impact of additional confounding control for variables collected from self-reported data.

J Clin Pharm Ther 2019 Aug 7;44(4):623-631. Epub 2019 Apr 7.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/jcpt.12836DOI Listing
August 2019

Amiodarone use and the risk of acute pancreatitis: Influence of different exposure definitions.

Pharmacoepidemiol Drug Saf 2019 Aug 2. Epub 2019 Aug 2.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/pds.4851DOI Listing
August 2019

Risk of Nephrotic Syndrome for Non-Steroidal Anti-Inflammatory Drug Users.

Clin J Am Soc Nephrol 2019 Aug 15. Epub 2019 Aug 15.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.2215/CJN.14331218DOI Listing
August 2019

Subsequent Event Risk in Individuals With Established Coronary Heart Disease.

Authors:
Riyaz S Patel Vinicius Tragante Amand F Schmidt Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behloui Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Marie-Pierre Dubé Line Dufresne Niclas Eriksson Luisa Foco Markus Scholz Crystel M Gijsberts Charlotte Glinge Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Salma Kotti Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica Van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Lawien Al Ali Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Thomas Engstrøm Natalie Fitzpatrick Kim Fox Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Christopher Newton-Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Eric H Boersma Peter Bogaty Michiel L Bots Hermann Brenner Jasper J Brugts Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Nicolas Danchin Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Diederick E Grobbee Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Reza Jabbari Julie A Johnson J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm B K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Anna Niemcunowicz-Janica Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Agneta Siegbahn Tabassome Simon Juha Sinisalo J Gustav Smith John A Spertus Steen Stender Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jean-Claude Tardif Jurriën M Ten Berg Jacob Tfelt-Hansen George Thanassoulis Joachim Thiery Christian Torp-Pedersen Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Peter E Weeke Pim Van der Harst Chim C Lang Naveed Sattar Vicky A Cameron Jeffrey L Anderson James M Brophy Guillaume Pare Benjamin D Horne Winfried März Lars Wallentin Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 Apr 21;12(4):e002470. Epub 2019 Mar 21.

Institute of Health Informatics (N.F., A. Timmis, H.H., F.W.A.), Faculty of Population Health Science, University College London, United Kingdom.

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http://dx.doi.org/10.1161/CIRCGEN.119.002470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629546PMC
April 2019

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.

Authors:
Riyaz S Patel Amand F Schmidt Vinicius Tragante Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Marie-Pierre Dubé Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behlouli Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Line Dufresne Niclas Eriksson Luisa Foco Crystel M Gijsberts Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Natalie Fitzpatrick Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Chris Newton Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Peter Bogaty Gert J de Borst Hermann Brenner Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Julie A Johnson Pim A de Jong J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm Bakhtawar K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Witold Pepinski Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Markus Scholz Agneta Siegbahn Juha Sinisalo J Gustav Smith John A Spertus Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jurriën M Ten Berg George Thanassoulis Joachim Thiery Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Pim Van der Harst Jean-Claude Tardif Naveed Sattar Chim C Lang Guillaume Pare James M Brophy Jeffrey L Anderson Winfried März Lars Wallentin Vicky A Cameron Benjamin D Horne Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 Apr 21;12(4):e002471. Epub 2019 Mar 21.

Institute of Cardiovascular Science, Faculty of Population Health Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A.).

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http://dx.doi.org/10.1161/CIRCGEN.119.002471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625876PMC
April 2019

Cyclo-oxygenase selectivity and chemical groups of nonsteroidal anti-inflammatory drugs and the frequency of reporting hypersensitivity reactions: a case/noncase study in VigiBase.

Fundam Clin Pharmacol 2019 Mar 12. Epub 2019 Mar 12.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, PO Box 80082, 3508 TB, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/fcp.12463DOI Listing
March 2019

Postauthorization Changes to Specific Obligations of Conditionally Authorized Medicines in the European Union: A Retrospective Cohort Study.

Clin Pharmacol Ther 2019 Feb 12;105(2):426-435. Epub 2018 Aug 12.

Innovation Studies, Copernicus Institute of Sustainable Development, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/cpt.1169DOI Listing
February 2019

Non-steroidal anti-inflammatory drugs and the risk of out-of-hospital cardiac arrest: a case-control study.

Europace 2019 Jan;21(1):99-105

Department of Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, DD, the Netherlands.

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http://dx.doi.org/10.1093/europace/euy180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321960PMC
January 2019

How pharmacoepidemiology networks can manage distributed analyses to improve replicability and transparency and minimize bias.

Pharmacoepidemiol Drug Saf 2019 Jan 15. Epub 2019 Jan 15.

Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Canada.

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http://doi.wiley.com/10.1002/pds.4722
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http://dx.doi.org/10.1002/pds.4722DOI Listing
January 2019

Using a single noninferiority margin or preserved fraction for an entire pharmacological class was found to be inappropriate.

J Clin Epidemiol 2018 Dec 25;104:15-23. Epub 2018 Aug 25.

Professor of Pharmacoepidemiologic Methods, Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands; and Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jclinepi.2018.07.004DOI Listing
December 2018

Challenges in Advanced Therapy Medicinal Product Development: A Survey among Companies in Europe.

Mol Ther Methods Clin Dev 2018 Dec 11;11:121-130. Epub 2018 Oct 11.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584 CG Utrecht, the Netherland.

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https://linkinghub.elsevier.com/retrieve/pii/S23290501183009
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http://dx.doi.org/10.1016/j.omtm.2018.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234262PMC
December 2018

Medications Recommended for Secondary Prevention After First Acute Coronary Syndrome: Effectiveness of Treatment Combinations in a Real-Life Setting.

Clin Pharmacol Ther 2018 06 28;103(6):1038-1046. Epub 2017 Sep 28.

University of Bordeaux, INSERM, Bordeaux Population Health Research Center, Team Pharmacoepidemiology, Bordeaux, France.

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http://dx.doi.org/10.1002/cpt.864DOI Listing
June 2018

Pattern of risks of rheumatoid arthritis among patients using statins: A cohort study with the clinical practice research datalink.

PLoS One 2018 23;13(2):e0193297. Epub 2018 Feb 23.

Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Faculty of Sciences, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193297PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825093PMC
May 2018

The impact of age and sex on the reporting of cough and angioedema with renin-angiotensin system inhibitors: a case/noncase study in VigiBase.

Fundam Clin Pharmacol 2017 Dec 5;31(6):676-684. Epub 2017 Sep 5.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, PO Box 80 082, 3508 TB, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/fcp.12313DOI Listing
December 2017

The impact of serum potassium-influencing antihypertensive drugs on the risk of out-of-hospital cardiac arrest: A case-control study.

Br J Clin Pharmacol 2017 Nov 16;83(11):2541-2548. Epub 2017 Aug 16.

Department of Cardiology, Heart Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1111/bcp.13356
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http://dx.doi.org/10.1111/bcp.13356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651316PMC
November 2017

Gastrointestinal toxicity among patients taking selective COX-2 inhibitors or conventional NSAIDs, alone or combined with proton pump inhibitors: a case-control study.

Pharmacoepidemiol Drug Saf 2017 Oct 31;26(10):1141-1148. Epub 2017 Mar 31.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute of Pharmaceutical Sciences, The Netherlands.

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http://dx.doi.org/10.1002/pds.4183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655916PMC
October 2017

More Dose-dependent Side Effects with Mercaptopurine over Azathioprine in IBD Treatment Due to Relatively Higher Dosing.

Inflamm Bowel Dis 2017 10;23(10):1873-1881

Departments of *Gastroenterology, †Human Genetics, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands; ‡Department of Clinical Pharmacy, Pharmacology and Toxicology, Zuyderland Medical Center, Sittard-Geleen, the Netherlands; §Department for Health Evidence, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands; ‖Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht University, Utrecht, the Netherlands; ¶Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, the Netherlands; and **Department of Clinical Pharmacy, Máxima Medical Center, Veldhoven, the Netherlands.

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http://dx.doi.org/10.1097/MIB.0000000000001163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598908PMC
October 2017

Pattern of risks of systemic lupus erythematosus among statin users: a population-based cohort study.

Ann Rheum Dis 2017 Oct 6;76(10):1723-1730. Epub 2017 Jul 6.

School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2016-210936DOI Listing
October 2017

Quantification of the risk of liver injury associated with flucloxacillin: a UK population-based cohort study.

J Antimicrob Chemother 2017 09;72(9):2636-2646

Department of Non-communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.

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http://dx.doi.org/10.1093/jac/dkx183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890755PMC
September 2017

Defining the noninferiority margin and analysing noninferiority: An overview.

Br J Clin Pharmacol 2017 08 6;83(8):1636-1642. Epub 2017 Apr 6.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, P.O.Box 80082, 3508, TB, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/bcp.13280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510081PMC
August 2017

Patterns of antiplatelet drug use after a first myocardial infarction during a 10-year period.

Br J Clin Pharmacol 2017 03 24;83(3):632-641. Epub 2016 Oct 24.

Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands.

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http://dx.doi.org/10.1111/bcp.13139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306486PMC
March 2017

Methods of defining the non-inferiority margin in randomized, double-blind controlled trials: a systematic review.

Trials 2017 03 7;18(1):107. Epub 2017 Mar 7.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, PO Box 80082, 3408 TB, Utrecht, The Netherlands.

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http://dx.doi.org/10.1186/s13063-017-1859-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341347PMC
March 2017

Assessment of channeling bias among initiators of glucose-lowering drugs: A UK cohort study.

Clin Epidemiol 2017 18;9:19-30. Epub 2017 Jan 18.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, the Netherlands.

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https://www.dovepress.com/assessment-of-channeling-bias-amon
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http://dx.doi.org/10.2147/CLEP.S124054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261549PMC
January 2017

A systematic literature review on the efficacy-effectiveness gap: comparison of randomized controlled trials and observational studies of glucose-lowering drugs.

Clin Epidemiol 2017 23;9:41-51. Epub 2017 Jan 23.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.2147/CLEP.S121991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271378PMC
January 2017

Risk patterns in drug safety study using relative times by accelerated failure time models when proportional hazards assumption is questionable: an illustrative case study of cancer risk of patients on glucose-lowering therapies.

Pharm Stat 2015 Sep-Oct;14(5):382-94. Epub 2015 Jun 30.

Department of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, P.O. Box 80082, 3508, TB, The Netherlands.

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http://doi.wiley.com/10.1002/pst.1697
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http://dx.doi.org/10.1002/pst.1697DOI Listing
September 2016

Optimising case detection within UK electronic health records: use of multiple linked databases for detecting liver injury.

BMJ Open 2016 09 2;6(9):e012102. Epub 2016 Sep 2.

Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

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http://dx.doi.org/10.1136/bmjopen-2016-012102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020862PMC
September 2016

Best (but oft-forgotten) practices: propensity score methods in clinical nutrition research.

Am J Clin Nutr 2016 08 13;104(2):247-58. Epub 2016 Jul 13.

Utrecht Institute for Pharmaceutical Sciences, Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University Utrecht, Netherlands; and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands

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http://dx.doi.org/10.3945/ajcn.115.125914DOI Listing
August 2016

Methods to control for unmeasured confounding in pharmacoepidemiology: an overview.

Int J Clin Pharm 2016 Jun 18;38(3):714-23. Epub 2016 Apr 18.

Division of Pharmacoepidemiology and Clinical Pharmacology, University of Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s11096-016-0299-0DOI Listing
June 2016

The IMI PROTECT project: purpose, organizational structure, and procedures.

Pharmacoepidemiol Drug Saf 2016 Mar;25 Suppl 1:5-10

Utrecht Institute for Pharmaceutical Sciences (UIPS), Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, the Netherlands.

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http://dx.doi.org/10.1002/pds.3933DOI Listing
March 2016

Case-only designs for studying the association of antidepressants and hip or femur fracture.

Pharmacoepidemiol Drug Saf 2016 Mar;25 Suppl 1:103-13

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/pds.3850DOI Listing
March 2016

Methodological comparison of marginal structural model, time-varying Cox regression, and propensity score methods: the example of antidepressant use and the risk of hip fracture.

Pharmacoepidemiol Drug Saf 2016 Mar;25 Suppl 1:114-21

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1002/pds.3864DOI Listing
March 2016

Instrumental variables analysis using multiple databases: an example of antidepressant use and risk of hip fracture.

Pharmacoepidemiol Drug Saf 2016 Mar;25 Suppl 1:122-31

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands.

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http://doi.wiley.com/10.1002/pds.3863
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http://dx.doi.org/10.1002/pds.3863DOI Listing
March 2016

Evaluating different physician's prescribing preference based instrumental variables in two primary care databases: a study of inhaled long-acting beta2-agonist use and the risk of myocardial infarction.

Pharmacoepidemiol Drug Saf 2016 Mar;25 Suppl 1:132-41

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/pds.3860DOI Listing
March 2016

Adjusting for Confounding in Early Postlaunch Settings: Going Beyond Logistic Regression Models.

Epidemiology 2016 Jan;27(1):133-42

From the aJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands; bDivision of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands; cDepartment of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands; and dInstitute of Cardiovascular Science, Faculty of Population Health, University College London, London, United Kingdom.

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http://dx.doi.org/10.1097/EDE.0000000000000388DOI Listing
January 2016

Unmeasured confounding in pharmacoepidemiology.

Ann Epidemiol 2016 Jan 7;26(1):85-6. Epub 2015 Nov 7.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.annepidem.2015.10.007DOI Listing
January 2016

Identification of Patients With Variants in TPMT and Dose Reduction Reduces Hematologic Events During Thiopurine Treatment of Inflammatory Bowel Disease.

Gastroenterology 2015 Oct 11;149(4):907-17.e7. Epub 2015 Jun 11.

Department of Human Genetics, Donders Centre for Neuroscience, Radboud university medical center, Nijmegen, The Netherlands; Department of Psychiatry, Donders Centre for Neuroscience, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1053/j.gastro.2015.06.002DOI Listing
October 2015

Comparative Performance of ATRIA, CHADS2, and CHA2DS2-VASc Risk Scores Predicting Stroke in Patients With Atrial Fibrillation: Results From a National Primary Care Database.

J Am Coll Cardiol 2015 Oct;66(17):1851-9

Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands; Department of Health eResearch, University of Manchester, Manchester, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2015.08.033DOI Listing
October 2015

Left truncation results in substantial bias of the relation between time-dependent exposures and adverse events.

Ann Epidemiol 2015 Aug 1;25(8):590-6. Epub 2015 Apr 1.

Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.annepidem.2015.03.019DOI Listing
August 2015

Performance of prior event rate ratio adjustment method in pharmacoepidemiology: a simulation study.

Pharmacoepidemiol Drug Saf 2015 May 20;24(5):468-77. Epub 2014 Nov 20.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1002/pds.3724DOI Listing
May 2015

Bayesian methods including nonrandomized study data increased the efficiency of postlaunch RCTs.

J Clin Epidemiol 2015 Apr 28;68(4):387-96. Epub 2014 Nov 28.

Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Universiteitsweg 100, P.O. Box 85500, 3508 GA Utrecht, The Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Universiteitsweg 99, P.O. Box 80082, 3508 TB Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.jclinepi.2014.11.015DOI Listing
April 2015

Reporting of covariate selection and balance assessment in propensity score analysis is suboptimal: a systematic review.

J Clin Epidemiol 2015 Feb 26;68(2):112-21. Epub 2014 Nov 26.

Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, the Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jclinepi.2014.08.011DOI Listing
February 2015

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.

Authors:
Daniel I Swerdlow David Preiss Karoline B Kuchenbaecker Michael V Holmes Jorgen E L Engmann Tina Shah Reecha Sofat Stefan Stender Paul C D Johnson Robert A Scott Maarten Leusink Niek Verweij Stephen J Sharp Yiran Guo Claudia Giambartolomei Christina Chung Anne Peasey Antoinette Amuzu KaWah Li Jutta Palmen Philip Howard Jackie A Cooper Fotios Drenos Yun R Li Gordon Lowe John Gallacher Marlene C W Stewart Ioanna Tzoulaki Sarah G Buxbaum Daphne L van der A Nita G Forouhi N Charlotte Onland-Moret Yvonne T van der Schouw Renate B Schnabel Jaroslav A Hubacek Ruzena Kubinova Migle Baceviciene Abdonas Tamosiunas Andrzej Pajak Roman Topor-Madry Urszula Stepaniak Sofia Malyutina Damiano Baldassarre Bengt Sennblad Elena Tremoli Ulf de Faire Fabrizio Veglia Ian Ford J Wouter Jukema Rudi G J Westendorp Gert Jan de Borst Pim A de Jong Ale Algra Wilko Spiering Anke H Maitland-van der Zee Olaf H Klungel Anthonius de Boer Pieter A Doevendans Charles B Eaton Jennifer G Robinson David Duggan John Kjekshus John R Downs Antonio M Gotto Anthony C Keech Roberto Marchioli Gianni Tognoni Peter S Sever Neil R Poulter David D Waters Terje R Pedersen Pierre Amarenco Haruo Nakamura John J V McMurray James D Lewsey Daniel I Chasman Paul M Ridker Aldo P Maggioni Luigi Tavazzi Kausik K Ray Sreenivasa Rao Kondapally Seshasai JoAnn E Manson Jackie F Price Peter H Whincup Richard W Morris Debbie A Lawlor George Davey Smith Yoav Ben-Shlomo Pamela J Schreiner Myriam Fornage David S Siscovick Mary Cushman Meena Kumari Nick J Wareham W M Monique Verschuren Susan Redline Sanjay R Patel John C Whittaker Anders Hamsten Joseph A Delaney Caroline Dale Tom R Gaunt Andrew Wong Diana Kuh Rebecca Hardy Sekar Kathiresan Berta A Castillo Pim van der Harst Eric J Brunner Anne Tybjaerg-Hansen Michael G Marmot Ronald M Krauss Michael Tsai Josef Coresh Ronald C Hoogeveen Bruce M Psaty Leslie A Lange Hakon Hakonarson Frank Dudbridge Steve E Humphries Philippa J Talmud Mika Kivimäki Nicholas J Timpson Claudia Langenberg Folkert W Asselbergs Mikhail Voevoda Martin Bobak Hynek Pikhart James G Wilson Alex P Reiner Brendan J Keating Aroon D Hingorani Naveed Sattar

Lancet 2015 Jan 24;385(9965):351-61. Epub 2014 Sep 24.

BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1016/S0140-6736(14)61183-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322187PMC
January 2015

Sources of heterogeneity in case-control studies on associations between statins, ACE-inhibitors, and proton pump inhibitors and risk of pneumonia.

Eur J Epidemiol 2014 Oct 26;29(10):767-75. Epub 2014 Aug 26.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, PO Box 80082, 3508 TB, Utrecht, The Netherlands,

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http://dx.doi.org/10.1007/s10654-014-9941-0DOI Listing
October 2014

Concurrent use of statins and hormone therapy and risk of venous thromboembolism in postmenopausal women: a population-based case-control study.

Menopause 2014 Sep;21(9):1023-6

From the 1McGill Pharmacoepidemiology Research Unit, Departments of Epidemiology and Biostatistics and Medicine, Jewish General Hospital, McGill University, Montreal, QC, Canada; 2Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands; and 3Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1097/GME.0000000000000279DOI Listing
September 2014

Quantitative falsification of instrumental variables assumption using balance measures.

Epidemiology 2014 Sep;25(5):770-2

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands Department of Mathematical Psychology, Catholic University of Leuven, Leuven, Belgium Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands,

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http://dx.doi.org/10.1097/EDE.0000000000000152DOI Listing
September 2014

Statin use and markers of immunity in the Doetinchem cohort study.

PLoS One 2013 16;8(10):e77587. Epub 2013 Oct 16.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands ; Department of Toxicogenomics, Maastricht University Medical Centre, Maastricht, The Netherlands ; Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Faculty of Sciences, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077587PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797719PMC
August 2014

Propensity score balance measures in pharmacoepidemiology: a simulation study.

Pharmacoepidemiol Drug Saf 2014 Aug 29;23(8):802-11. Epub 2014 Jan 29.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/pds.3574DOI Listing
August 2014

Regulatory scientific advice on non-inferiority drug trials.

PLoS One 2013 5;8(9):e74818. Epub 2013 Sep 5.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, The Netherlands ; Medicines Evaluation Board, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074818PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764030PMC
July 2014

Exploring interaction effects in small samples increases rates of false-positive and false-negative findings: results from a systematic review and simulation study.

J Clin Epidemiol 2014 Jul 24;67(7):821-9. Epub 2014 Apr 24.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, P.O. Box 85500, 3508 GA Utrecht, The Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, P.O. Box 80082, 3508 TB Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.jclinepi.2014.02.008DOI Listing
July 2014

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.

Authors:
Michael V Holmes Caroline E Dale Luisa Zuccolo Richard J Silverwood Yiran Guo Zheng Ye David Prieto-Merino Abbas Dehghan Stella Trompet Andrew Wong Alana Cavadino Dagmar Drogan Sandosh Padmanabhan Shanshan Li Ajay Yesupriya Maarten Leusink Johan Sundstrom Jaroslav A Hubacek Hynek Pikhart Daniel I Swerdlow Andrie G Panayiotou Svetlana A Borinskaya Chris Finan Sonia Shah Karoline B Kuchenbaecker Tina Shah Jorgen Engmann Lasse Folkersen Per Eriksson Fulvio Ricceri Olle Melander Carlotta Sacerdote Dale M Gamble Sruti Rayaprolu Owen A Ross Stela McLachlan Olga Vikhireva Ivonne Sluijs Robert A Scott Vera Adamkova Leon Flicker Frank M van Bockxmeer Christine Power Pedro Marques-Vidal Tom Meade Michael G Marmot Jose M Ferro Sofia Paulos-Pinheiro Steve E Humphries Philippa J Talmud Irene Mateo Leach Niek Verweij Allan Linneberg Tea Skaaby Pieter A Doevendans Maarten J Cramer Pim van der Harst Olaf H Klungel Nicole F Dowling Anna F Dominiczak Meena Kumari Andrew N Nicolaides Cornelia Weikert Heiner Boeing Shah Ebrahim Tom R Gaunt Jackie F Price Lars Lannfelt Anne Peasey Ruzena Kubinova Andrzej Pajak Sofia Malyutina Mikhail I Voevoda Abdonas Tamosiunas Anke H Maitland-van der Zee Paul E Norman Graeme J Hankey Manuela M Bergmann Albert Hofman Oscar H Franco Jackie Cooper Jutta Palmen Wilko Spiering Pim A de Jong Diana Kuh Rebecca Hardy Andre G Uitterlinden M Arfan Ikram Ian Ford Elina Hyppönen Osvaldo P Almeida Nicholas J Wareham Kay-Tee Khaw Anders Hamsten Lise Lotte N Husemoen Anne Tjønneland Janne S Tolstrup Eric Rimm Joline W J Beulens W M Monique Verschuren N Charlotte Onland-Moret Marten H Hofker S Goya Wannamethee Peter H Whincup Richard Morris Astrid M Vicente Hugh Watkins Martin Farrall J Wouter Jukema James Meschia L Adrienne Cupples Stephen J Sharp Myriam Fornage Charles Kooperberg Andrea Z LaCroix James Y Dai Matthew B Lanktree David S Siscovick Eric Jorgenson Bonnie Spring Josef Coresh Yun R Li Sarah G Buxbaum Pamela J Schreiner R Curtis Ellison Michael Y Tsai Sanjay R Patel Susan Redline Andrew D Johnson Ron C Hoogeveen Hakon Hakonarson Jerome I Rotter Eric Boerwinkle Paul I W de Bakker Mika Kivimaki Folkert W Asselbergs Naveed Sattar Debbie A Lawlor John Whittaker George Davey Smith Kenneth Mukamal Bruce M Psaty James G Wilson Leslie A Lange Ajna Hamidovic Aroon D Hingorani Børge G Nordestgaard Martin Bobak David A Leon Claudia Langenberg Tom M Palmer Alex P Reiner Brendan J Keating Frank Dudbridge Juan P Casas

BMJ 2014 Jul 10;349:g4164. Epub 2014 Jul 10.

Genetic Epidemiology Group, Institute of Cardiovascular Science, Department of Epidemiology and Public Health, University College London, UK Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091648PMC
http://dx.doi.org/10.1136/bmj.g4164DOI Listing
July 2014

Propensity score methods and unobserved covariate imbalance: comments on "squeezing the balloon".

Health Serv Res 2014 Jun 24;49(3):1074-82. Epub 2014 Jan 24.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/1475-6773.12152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231586PMC
June 2014

Justification of exclusion criteria was underreported in a review of cardiovascular trials.

J Clin Epidemiol 2014 Jun 5;67(6):635-44. Epub 2014 Mar 5.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6.131, P.O. Box 85500, 3508 GA Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.jclinepi.2013.12.005DOI Listing
June 2014

Bridging differences in outcomes of pharmacoepidemiological studies: design and first results of the PROTECT project.

Curr Clin Pharmacol 2014 May;9(2):130-8

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, P.O. Box 80082 3508 TB Utrecht, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083447PMC
May 2014

Antiepileptic drug use in seven electronic health record databases in Europe: a methodologic comparison.

Epilepsia 2014 May 27;55(5):666-73. Epub 2014 Feb 27.

Division of Pharmacoepidemiology & Clinical Pharmacology, Faculty of Science, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/epi.12557DOI Listing
May 2014

Development of predictive genetic tests for improving the safety of new medicines: the utilization of routinely collected electronic health records.

Drug Discov Today 2014 Apr 14;19(4):361-6. Epub 2013 Nov 14.

Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK; Department of Pharmacoepidemiology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, The Netherlands; Clinical Practice Research Datalink (CPRD), Medicines and Healthcare Products Regulatory Agency, London, UK.

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http://dx.doi.org/10.1016/j.drudis.2013.11.003DOI Listing
April 2014

Pharmacogenomics of oral antiplatelet drugs.

Pharmacogenomics 2014 Mar;15(4):509-28

Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.2217/pgs.14.16DOI Listing
March 2014

Performance of instrumental variable methods in cohort and nested case-control studies: a simulation study.

Pharmacoepidemiol Drug Saf 2014 Feb 5;23(2):165-77. Epub 2013 Dec 5.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1002/pds.3555DOI Listing
February 2014

The SLCO1B1 c.521T>C polymorphism is associated with dose decrease or switching during statin therapy in the Rotterdam Study.

Pharmacogenet Genomics 2014 Jan;24(1):43-51

Departments of aEpidemiology bInternal Medicine, Erasmus Medical Center, Rotterdam cDrug Safety Unit, The Health Care Inspectorate dDepartment of Hospital Pharmacy, Pharmacy Foundation of The Hague Hospitals - HAGA eNetherlands Consortium of Healthy Aging, The Hague fDepartment of Pharmacoepidemiology & Clinical Pharmacotherapy, Utrecht University, Utrecht gDepartment of Clinical Pharmacy, St Antonius Hospital Nieuwegein, Nieuwegein hDepartment of Hospital Pharmacy, Pharmacy Foundation of Haarlem Hospitals, Haarlem, The Netherlands iDepartment of Molecular Genetics, Pharmacogenetics and Hormone Research, Bicêtre Hospital, Paris, France.

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http://dx.doi.org/10.1097/FPC.0000000000000018DOI Listing
January 2014

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.

Authors:
Michael V Holmes Tabassome Simon Holly J Exeter Lasse Folkersen Folkert W Asselbergs Montse Guardiola Jackie A Cooper Jutta Palmen Jaroslav A Hubacek Kathryn F Carruthers Benjamin D Horne Kimberly D Brunisholz Jessica L Mega Erik P A van Iperen Mingyao Li Maarten Leusink Stella Trompet Jeffrey J W Verschuren G Kees Hovingh Abbas Dehghan Christopher P Nelson Salma Kotti Nicolas Danchin Markus Scholz Christiane L Haase Dietrich Rothenbacher Daniel I Swerdlow Karoline B Kuchenbaecker Eleonora Staines-Urias Anuj Goel Ferdinand van 't Hooft Karl Gertow Ulf de Faire Andrie G Panayiotou Elena Tremoli Damiano Baldassarre Fabrizio Veglia Lesca M Holdt Frank Beutner Ron T Gansevoort Gerjan J Navis Irene Mateo Leach Lutz P Breitling Hermann Brenner Joachim Thiery Dhayana Dallmeier Anders Franco-Cereceda Jolanda M A Boer Jeffrey W Stephens Marten H Hofker Alain Tedgui Albert Hofman André G Uitterlinden Vera Adamkova Jan Pitha N Charlotte Onland-Moret Maarten J Cramer Hendrik M Nathoe Wilko Spiering Olaf H Klungel Meena Kumari Peter H Whincup David A Morrow Peter S Braund Alistair S Hall Anders G Olsson Pieter A Doevendans Mieke D Trip Martin D Tobin Anders Hamsten Hugh Watkins Wolfgang Koenig Andrew N Nicolaides Daniel Teupser Ian N M Day John F Carlquist Tom R Gaunt Ian Ford Naveed Sattar Sotirios Tsimikas Gregory G Schwartz Debbie A Lawlor Richard W Morris Manjinder S Sandhu Rudolf Poledne Anke H Maitland-van der Zee Kay-Tee Khaw Brendan J Keating Pim van der Harst Jackie F Price Shamir R Mehta Salim Yusuf Jaqueline C M Witteman Oscar H Franco J Wouter Jukema Peter de Knijff Anne Tybjaerg-Hansen Daniel J Rader Martin Farrall Nilesh J Samani Mika Kivimaki Keith A A Fox Steve E Humphries Jeffrey L Anderson S Matthijs Boekholdt Tom M Palmer Per Eriksson Guillaume Paré Aroon D Hingorani Marc S Sabatine Ziad Mallat Juan P Casas Philippa J Talmud

J Am Coll Cardiol 2013 Nov 31;62(21):1966-1976. Epub 2013 Jul 31.

Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.jacc.2013.06.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826105PMC
November 2013

Robust association of the LPA locus with low-density lipoprotein cholesterol lowering response to statin treatment in a meta-analysis of 30 467 individuals from both randomized control trials and observational studies and association with coronary artery disease outcome during statin treatment.

Pharmacogenet Genomics 2013 Oct;23(10):518-25

aMedical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee bWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK cDivision of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University dDepartment of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1097/FPC.0b013e3283642fd6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110714PMC
October 2013

Should non-inferiority drug trials be banned altogether?

Drug Discov Today 2013 Jun 14;18(11-12):601-4. Epub 2013 Jan 14.

Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences UIPS, Utrecht University, PO Box 80082, 3508TB Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.drudis.2013.01.003DOI Listing
June 2013

Differences in interaction and subgroup-specific effects were observed between randomized and nonrandomized studies in three empirical examples.

J Clin Epidemiol 2013 Jun 16;66(6):599-607. Epub 2013 Mar 16.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.jclinepi.2012.08.008DOI Listing
June 2013

Phase IV non-inferiority trials and additional claims of benefit.

BMC Med Res Methodol 2013 May 30;13:70. Epub 2013 May 30.

Julius Center for Health Sciences and Primary Care, Utrecht University Medical Center, Utrecht, The Netherlands.

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http://dx.doi.org/10.1186/1471-2288-13-70DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679839PMC
May 2013

Time-dependent propensity score and collider-stratification bias: an example of beta2-agonist use and the risk of coronary heart disease.

Eur J Epidemiol 2013 Apr 25;28(4):291-9. Epub 2013 Jan 25.

Department of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands.

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http://link.springer.com/10.1007/s10654-013-9766-2
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http://dx.doi.org/10.1007/s10654-013-9766-2DOI Listing
April 2013

Adjustment for continuous confounders: an example of how to prevent residual confounding.

CMAJ 2013 Mar 11;185(5):401-6. Epub 2013 Feb 11.

Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands.

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http://dx.doi.org/10.1503/cmaj.120592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602256PMC
March 2013

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.

Authors:
Benjamin F Voight Gina M Peloso Marju Orho-Melander Ruth Frikke-Schmidt Maja Barbalic Majken K Jensen George Hindy Hilma Hólm Eric L Ding Toby Johnson Heribert Schunkert Nilesh J Samani Robert Clarke Jemma C Hopewell John F Thompson Mingyao Li Gudmar Thorleifsson Christopher Newton-Cheh Kiran Musunuru James P Pirruccello Danish Saleheen Li Chen Alexandre F R Stewart Arne Schillert Unnur Thorsteinsdottir Gudmundur Thorgeirsson Sonia Anand James C Engert Thomas Morgan John Spertus Monika Stoll Klaus Berger Nicola Martinelli Domenico Girelli Pascal P McKeown Christopher C Patterson Stephen E Epstein Joseph Devaney Mary-Susan Burnett Vincent Mooser Samuli Ripatti Ida Surakka Markku S Nieminen Juha Sinisalo Marja-Liisa Lokki Markus Perola Aki Havulinna Ulf de Faire Bruna Gigante Erik Ingelsson Tanja Zeller Philipp Wild Paul I W de Bakker Olaf H Klungel Anke-Hilse Maitland-van der Zee Bas J M Peters Anthonius de Boer Diederick E Grobbee Pieter W Kamphuisen Vera H M Deneer Clara C Elbers N Charlotte Onland-Moret Marten H Hofker Cisca Wijmenga W M Monique Verschuren Jolanda M A Boer Yvonne T van der Schouw Asif Rasheed Philippe Frossard Serkalem Demissie Cristen Willer Ron Do Jose M Ordovas Gonçalo R Abecasis Michael Boehnke Karen L Mohlke Mark J Daly Candace Guiducci Noël P Burtt Aarti Surti Elena Gonzalez Shaun Purcell Stacey Gabriel Jaume Marrugat John Peden Jeanette Erdmann Patrick Diemert Christina Willenborg Inke R König Marcus Fischer Christian Hengstenberg Andreas Ziegler Ian Buysschaert Diether Lambrechts Frans Van de Werf Keith A Fox Nour Eddine El Mokhtari Diana Rubin Jürgen Schrezenmeir Stefan Schreiber Arne Schäfer John Danesh Stefan Blankenberg Robert Roberts Ruth McPherson Hugh Watkins Alistair S Hall Kim Overvad Eric Rimm Eric Boerwinkle Anne Tybjaerg-Hansen L Adrienne Cupples Muredach P Reilly Olle Melander Pier M Mannucci Diego Ardissino David Siscovick Roberto Elosua Kari Stefansson Christopher J O'Donnell Veikko Salomaa Daniel J Rader Leena Peltonen Stephen M Schwartz David Altshuler Sekar Kathiresan

Lancet 2012 Aug 17;380(9841):572-80. Epub 2012 May 17.

Department of Pharmacology, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/S0140-6736(12)60312-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419820PMC
August 2012

Angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and the risk of developing rheumatoid arthritis in antihypertensive drug users.

Pharmacoepidemiol Drug Saf 2012 Aug 6;21(8):835-43. Epub 2012 Jun 6.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.

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http://dx.doi.org/10.1002/pds.3291DOI Listing
August 2012

Effects of n-3 fatty acids on major cardiovascular events in statin users and non-users with a history of myocardial infarction.

Eur Heart J 2012 Jul 1;33(13):1582-8. Epub 2012 Feb 1.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/eurheartj/ehr499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388014PMC
July 2012

Potential of adaptive clinical trial designs in pharmacogenetic research.

Pharmacogenomics 2012 Apr;13(5):571-8

Julius Center for Health Sciences & Primary Care, University Medical Center Utrecht, The Netherlands.

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http://dx.doi.org/10.2217/pgs.12.10DOI Listing
April 2012

Statins accelerate the onset of collagen type II-induced arthritis in mice.

Arthritis Res Ther 2012 Apr 26;14(2):R90. Epub 2012 Apr 26.

Laboratory for Health Protection Research, National Institute for Public Health and the Environment, Antonie van Leeuwenhoeklaan 9, PO Box 1, 3720 BA Bilthoven, The Netherlands.

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http://dx.doi.org/10.1186/ar3814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446464PMC
April 2012

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.

Authors:
Richa Saxena Clara C Elbers Yiran Guo Inga Peter Tom R Gaunt Jessica L Mega Matthew B Lanktree Archana Tare Berta Almoguera Castillo Yun R Li Toby Johnson Marcel Bruinenberg Diane Gilbert-Diamond Ramakrishnan Rajagopalan Benjamin F Voight Ashok Balasubramanyam John Barnard Florianne Bauer Jens Baumert Tushar Bhangale Bernhard O Böhm Peter S Braund Paul R Burton Hareesh R Chandrupatla Robert Clarke Rhonda M Cooper-DeHoff Errol D Crook George Davey-Smith Ian N Day Anthonius de Boer Mark C H de Groot Fotios Drenos Jane Ferguson Caroline S Fox Clement E Furlong Quince Gibson Christian Gieger Lisa A Gilhuijs-Pederson Joseph T Glessner Anuj Goel Yan Gong Struan F A Grant Diederick E Grobbee Claire Hastie Steve E Humphries Cecilia E Kim Mika Kivimaki Marcus Kleber Christa Meisinger Meena Kumari Taimour Y Langaee Debbie A Lawlor Mingyao Li Maximilian T Lobmeyer Anke-Hilse Maitland-van der Zee Matthijs F L Meijs Cliona M Molony David A Morrow Gurunathan Murugesan Solomon K Musani Christopher P Nelson Stephen J Newhouse Jeffery R O'Connell Sandosh Padmanabhan Jutta Palmen Sanjey R Patel Carl J Pepine Mary Pettinger Thomas S Price Suzanne Rafelt Jane Ranchalis Asif Rasheed Elisabeth Rosenthal Ingo Ruczinski Sonia Shah Haiqing Shen Günther Silbernagel Erin N Smith Annemieke W M Spijkerman Alice Stanton Michael W Steffes Barbara Thorand Mieke Trip Pim van der Harst Daphne L van der A Erik P A van Iperen Jessica van Setten Jana V van Vliet-Ostaptchouk Niek Verweij Bruce H R Wolffenbuttel Taylor Young M Hadi Zafarmand Joseph M Zmuda Michael Boehnke David Altshuler Mark McCarthy W H Linda Kao James S Pankow Thomas P Cappola Peter Sever Neil Poulter Mark Caulfield Anna Dominiczak Denis C Shields Deepak L Bhatt Deepak Bhatt Li Zhang Sean P Curtis John Danesh Juan P Casas Yvonne T van der Schouw N Charlotte Onland-Moret Pieter A Doevendans Gerald W Dorn Martin Farrall Garret A FitzGerald Anders Hamsten Robert Hegele Aroon D Hingorani Marten H Hofker Gordon S Huggins Thomas Illig Gail P Jarvik Julie A Johnson Olaf H Klungel William C Knowler Wolfgang Koenig Winfried März James B Meigs Olle Melander Patricia B Munroe Braxton D Mitchell Susan J Bielinski Daniel J Rader Muredach P Reilly Stephen S Rich Jerome I Rotter Danish Saleheen Nilesh J Samani Eric E Schadt Alan R Shuldiner Roy Silverstein Kandice Kottke-Marchant Philippa J Talmud Hugh Watkins Folkert W Asselbergs Folkert Asselbergs Paul I W de Bakker Jeanne McCaffery Cisca Wijmenga Marc S Sabatine James G Wilson Alex Reiner Donald W Bowden Hakon Hakonarson David S Siscovick Brendan J Keating

Am J Hum Genet 2012 Mar 9;90(3):410-25. Epub 2012 Feb 9.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, 02114, USA.

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http://dx.doi.org/10.1016/j.ajhg.2011.12.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309185PMC
March 2012

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.

Authors:
Daniel I Swerdlow Michael V Holmes Karoline B Kuchenbaecker Jorgen E L Engmann Tina Shah Reecha Sofat Yiran Guo Christina Chung Anne Peasey Roman Pfister Simon P Mooijaart Helen A Ireland Maarten Leusink Claudia Langenberg Ka Wah Li Jutta Palmen Philip Howard Jackie A Cooper Fotios Drenos John Hardy Michael A Nalls Yun Rose Li Gordon Lowe Marlene Stewart Suzette J Bielinski Julian Peto Nicholas J Timpson John Gallacher Malcolm Dunlop Richard Houlston Ian Tomlinson Ioanna Tzoulaki Jian'an Luan Jolanda M A Boer Nita G Forouhi N Charlotte Onland-Moret Yvonne T van der Schouw Renate B Schnabel Jaroslav A Hubacek Ruzena Kubinova Migle Baceviciene Abdonas Tamosiunas Andrzej Pajak Roman Topor-Madry Sofia Malyutina Damiano Baldassarre Bengt Sennblad Elena Tremoli Ulf de Faire Luigi Ferrucci Stefania Bandenelli Toshiko Tanaka James F Meschia Andrew Singleton Gerjan Navis Irene Mateo Leach Stephan J L Bakker Ron T Gansevoort Ian Ford Stephen E Epstein Mary Susan Burnett Joe M Devaney J Wouter Jukema Rudi G J Westendorp Gert Jan de Borst Yolanda van der Graaf Pim A de Jong Anke-Hilse Mailand-van der Zee Olaf H Klungel Anthonius de Boer Pieter A Doevendans Jeffrey W Stephens Charles B Eaton Jennifer G Robinson JoAnn E Manson F Gerry Fowkes Timonthy M Frayling Jackie F Price Peter H Whincup Richard W Morris Debbie A Lawlor George Davey Smith Yoav Ben-Shlomo Susan Redline Leslie A Lange Meena Kumari Nick J Wareham W M Monique Verschuren Emelia J Benjamin John C Whittaker Anders Hamsten Frank Dudbridge J A Chris Delaney Andrew Wong Diana Kuh Rebecca Hardy Berta Almoguera Castillo John J Connolly Pim van der Harst Eric J Brunner Michael G Marmot Christina L Wassel Steve E Humphries Philippa J Talmud Mika Kivimaki Folkert W Asselbergs Mikhail Voevoda Martin Bobak Hynek Pikhart James G Wilson Hakon Hakonarson Alex P Reiner Brendan J Keating Naveed Sattar Aroon D Hingorani Juan Pablo Casas

Lancet 2012 Mar 14;379(9822):1214-24. Epub 2012 Mar 14.

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http://dx.doi.org/10.1016/S0140-6736(12)60110-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316968PMC
March 2012

Association between statin use and lupus-like syndrome using spontaneous reports.

Semin Arthritis Rheum 2011 Dec 24;41(3):373-81. Epub 2011 Aug 24.

Laboratory for Health Protection Research, National Institute for Public Health and Environment, Bilthoven, Netherlands.

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http://dx.doi.org/10.1016/j.semarthrit.2011.06.002DOI Listing
December 2011

Balance measures for propensity score methods: a clinical example on beta-agonist use and the risk of myocardial infarction.

Pharmacoepidemiol Drug Saf 2011 Nov 23;20(11):1130-7. Epub 2011 Sep 23.

Department of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/pds.2251DOI Listing
November 2011

Pharmacogenetics in randomized controlled trials: considerations for trial design.

Pharmacogenomics 2011 Oct;12(10):1485-92

Julius Center for Health Sciences & Primary Care, University Medical Center Utrecht, Stratenum 6.131, Utrecht, The Netherlands.

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https://www.futuremedicine.com/doi/10.2217/pgs.11.95
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http://dx.doi.org/10.2217/pgs.11.95DOI Listing
October 2011

Modelling approach to simulate reductions in LDL cholesterol levels after combined intake of statins and phytosterols/-stanols in humans.

Lipids Health Dis 2011 Oct 21;10:187. Epub 2011 Oct 21.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, P.O. Box 80082, 3508 TB Utrecht, The Netherlands.

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http://www.springerlink.com/index/J83PM466TL4118L7.pdf
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http://lipidworld.biomedcentral.com/articles/10.1186/1476-51
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http://dx.doi.org/10.1186/1476-511X-10-187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229468PMC
October 2011

Functional foods and dietary supplements: products at the interface between pharma and nutrition.

Eur J Pharmacol 2011 Sep 27;668 Suppl 1:S2-9. Epub 2011 Jul 27.

National Institute for Public Health and the Environment (RIVM), PO Box 1, 3720 BA Bilthoven, The Netherlands.

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http://dx.doi.org/10.1016/j.ejphar.2011.07.008DOI Listing
September 2011

Costs and health effects of adding functional foods containing phytosterols/-stanols to statin therapy in the prevention of cardiovascular disease.

Eur J Pharmacol 2011 Sep 27;668 Suppl 1:S91-100. Epub 2011 Jul 27.

National Institute for Public Health and the Environment (RIVM), PO Box 1, 3720 BA Bilthoven, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00142999110077
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http://dx.doi.org/10.1016/j.ejphar.2011.05.081DOI Listing
September 2011