Ola Hansson

Ola Hansson

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Ola Hansson

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Turning Vice into Virtue: Using Batch-Effects to Detect Errors in Large Genomic Data Sets.

Authors:
Fabrizio Mafessoni Rashmi B Prasad Leif Groop Ola Hansson Kay Prüfer

Genome Biol Evol 2018 10 1;10(10):2697-2708. Epub 2018 Oct 1.

Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

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https://academic.oup.com/gbe/article/10/10/2697/5094764
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http://dx.doi.org/10.1093/gbe/evy199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185451PMC
October 2018

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.

Authors:
Viktoria Gusarova Colm O'Dushlaine Tanya M Teslovich Peter N Benotti Tooraj Mirshahi Omri Gottesman Cristopher V Van Hout Michael F Murray Anubha Mahajan Jonas B Nielsen Lars Fritsche Anders Berg Wulff Daniel F Gudbjartsson Marketa Sjögren Connor A Emdin Robert A Scott Wen-Jane Lee Aeron Small Lydia C Kwee Om Prakash Dwivedi Rashmi B Prasad Shannon Bruse Alexander E Lopez John Penn Anthony Marcketta Joseph B Leader Christopher D Still H Lester Kirchner Uyenlinh L Mirshahi Amr H Wardeh Cassandra M Hartle Lukas Habegger Samantha N Fetterolf Teresa Tusie-Luna Andrew P Morris Hilma Holm Valgerdur Steinthorsdottir Patrick Sulem Unnur Thorsteinsdottir Jerome I Rotter Lee-Ming Chuang Scott Damrauer David Birtwell Chad M Brummett Amit V Khera Pradeep Natarajan Marju Orho-Melander Jason Flannick Luca A Lotta Cristen J Willer Oddgeir L Holmen Marylyn D Ritchie David H Ledbetter Andrew J Murphy Ingrid B Borecki Jeffrey G Reid John D Overton Ola Hansson Leif Groop Svati H Shah William E Kraus Daniel J Rader Yii-Der I Chen Kristian Hveem Nicholas J Wareham Sekar Kathiresan Olle Melander Kari Stefansson Børge G Nordestgaard Anne Tybjærg-Hansen Goncalo R Abecasis David Altshuler Jose C Florez Michael Boehnke Mark I McCarthy George D Yancopoulos David J Carey Alan R Shuldiner Aris Baras Frederick E Dewey Jesper Gromada

Nat Commun 2018 06 13;9(1):2252. Epub 2018 Jun 13.

Regeneron Pharmaceuticals, Tarrytown, 10591, NY, USA.

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http://dx.doi.org/10.1038/s41467-018-04611-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997992PMC
June 2018

Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables.

Authors:
Emma Ahlqvist Petter Storm Annemari Käräjämäki Mats Martinell Mozhgan Dorkhan Annelie Carlsson Petter Vikman Rashmi B Prasad Dina Mansour Aly Peter Almgren Ylva Wessman Nael Shaat Peter Spégel Hindrik Mulder Eero Lindholm Olle Melander Ola Hansson Ulf Malmqvist Åke Lernmark Kaj Lahti Tom Forsén Tiinamaija Tuomi Anders H Rosengren Leif Groop

Lancet Diabetes Endocrinol 2018 05 5;6(5):361-369. Epub 2018 Mar 5.

Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden; Finnish Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(18)30051-2DOI Listing
May 2018

N-methylnicotinamide is a signalling molecule produced in skeletal muscle coordinating energy metabolism.

Authors:
Kristoffer Ström David Morales-Alamo Filip Ottosson Anna Edlund Line Hjort Sine W Jörgensen Peter Almgren Yuedan Zhou Marcos Martin-Rincon Carl Ekman Alberto Pérez-López Ola Ekström Ismael Perez-Suarez Markus Mattiasson Pedro de Pablos-Velasco Nikolay Oskolkov Emma Ahlqvist Nils Wierup Lena Eliasson Allan Vaag Leif Groop Karin G Stenkula Céline Fernandez Jose A L Calbet Hans-Christer Holmberg Ola Hansson

Sci Rep 2018 02 14;8(1):3016. Epub 2018 Feb 14.

Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1038/s41598-018-21099-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813101PMC
February 2018

Glucose-Induced Changes in Gene Expression in Human Pancreatic Islets: Causes or Consequences of Chronic Hyperglycemia.

Authors:
Emilia Ottosson-Laakso Ulrika Krus Petter Storm Rashmi B Prasad Nikolay Oskolkov Emma Ahlqvist João Fadista Ola Hansson Leif Groop Petter Vikman

Diabetes 2017 12 7;66(12):3013-3028. Epub 2017 Sep 7.

Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.2337/db17-0311DOI Listing
December 2017

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

Authors:
Sara M Willems Daniel J Wright Felix R Day Katerina Trajanoska Peter K Joshi John A Morris Amy M Matteini Fleur C Garton Niels Grarup Nikolay Oskolkov Anbupalam Thalamuthu Massimo Mangino Jun Liu Ayse Demirkan Monkol Lek Liwen Xu Guan Wang Christopher Oldmeadow Kyle J Gaulton Luca A Lotta Eri Miyamoto-Mikami Manuel A Rivas Tom White Po-Ru Loh Mette Aadahl Najaf Amin John R Attia Krista Austin Beben Benyamin Søren Brage Yu-Ching Cheng Paweł Cięszczyk Wim Derave Karl-Fredrik Eriksson Nir Eynon Allan Linneberg Alejandro Lucia Myosotis Massidda Braxton D Mitchell Motohiko Miyachi Haruka Murakami Sandosh Padmanabhan Ashutosh Pandey Ioannis Papadimitriou Deepak K Rajpal Craig Sale Theresia M Schnurr Francesco Sessa Nick Shrine Martin D Tobin Ian Varley Louise V Wain Naomi R Wray Cecilia M Lindgren Daniel G MacArthur Dawn M Waterworth Mark I McCarthy Oluf Pedersen Kay-Tee Khaw Douglas P Kiel Yannis Pitsiladis Noriyuki Fuku Paul W Franks Kathryn N North Cornelia M van Duijn Karen A Mather Torben Hansen Ola Hansson Tim Spector Joanne M Murabito J Brent Richards Fernando Rivadeneira Claudia Langenberg John R B Perry Nick J Wareham Robert A Scott

Nat Commun 2017 07 12;8:16015. Epub 2017 Jul 12.

MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1038/ncomms16015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510175PMC
July 2017

No Additional Benefits of Block- Over Evenly-Distributed High-Intensity Interval Training within a Polarized Microcycle.

Authors:
Kerry McGawley Elisabeth Juudas Zuzanna Kazior Kristoffer Ström Eva Blomstrand Ola Hansson Hans-Christer Holmberg

Front Physiol 2017 13;8:413. Epub 2017 Jun 13.

Department of Health Sciences, Swedish Winter Sports Research Centre, Mid Sweden UniversityÖstersund, Sweden.

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http://dx.doi.org/10.3389/fphys.2017.00413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468439PMC
June 2017

LoFtool: a gene intolerance score based on loss-of-function variants in 60 706 individuals.

Authors:
João Fadista Nikolay Oskolkov Ola Hansson Leif Groop

Bioinformatics 2017 02;33(4):471-474

Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, Sweden and.

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http://dx.doi.org/10.1093/bioinformatics/btv602DOI Listing
February 2017

Salt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals: implications for insulin signalling and glucose uptake in human adipocytes.

Authors:
Johanna Säll Annie M L Pettersson Christel Björk Emma Henriksson Sebastian Wasserstrom Wilhelm Linder Yuedan Zhou Ola Hansson Daniel P Andersson Mikael Ekelund Eva Degerman Karin G Stenkula Jurga Laurencikiene Olga Göransson

Diabetologia 2017 02 2;60(2):314-323. Epub 2016 Nov 2.

Protein Phosphorylation Research Group, Department of Experimental Medical Science, Lund University, BMC C11, Klinikgatan 28, 22242, Lund, Sweden.

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http://dx.doi.org/10.1007/s00125-016-4141-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518086PMC
February 2017

CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.

Authors:
Mia Abels Matteo Riva Hedvig Bennet Emma Ahlqvist Oleg Dyachok Vini Nagaraj Liliya Shcherbina Rikard G Fred Wenny Poon Maria Sörhede-Winzell Joao Fadista Andreas Lindqvist Lena Kask Ramasri Sathanoori Marloes Dekker-Nitert Michael J Kuhar Bo Ahrén Claes B Wollheim Ola Hansson Anders Tengholm Malin Fex Erik Renström Leif Groop Valeriya Lyssenko Nils Wierup

Diabetologia 2016 09 23;59(9):1928-37. Epub 2016 Jun 23.

Lund University Diabetes Centre, Skåne University Hospital, Lund and Malmö, Sweden.

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http://dx.doi.org/10.1007/s00125-016-4020-6DOI Listing
September 2016

Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes.

Authors:
Rashmi B Prasad Anna Lessmark Peter Almgren Györgyi Kovacs Ola Hansson Nikolay Oskolkov Marta Vitai Claes Ladenvall Peter Kovacs Joao Fadista Michael Lachmann Yuedan Zhou Emily Sonestedt Wenny Poon Claes B Wollheim Marju Orho-Melander Michael Stumvoll Tiinamaija Tuomi Svante Pääbo Laszlo Koranyi Leif Groop

Diabetologia 2016 08 7;59(8):1702-13. Epub 2016 May 7.

Lund University Diabetes Centre, Department of Clinical Sciences, Lund University CRC, Skåne University Hospital Malmö, SE-205 02, Malmö, Sweden.

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http://dx.doi.org/10.1007/s00125-016-3973-9DOI Listing
August 2016

HMGB1 binds to the rs7903146 locus in TCF7L2 in human pancreatic islets.

Authors:
Yuedan Zhou Nikolay Oskolkov Liliya Shcherbina Joyce Ratti Kian-Hong Kock Jing Su Brian Martin Malin Zackrisson Oskolkova Olga Göransson Julie Bacon Weimin Li Saskia Bucciarelli Corrado Cilio Alvis Brazma Bradley Thatcher Johan Rung Nils Wierup Erik Renström Leif Groop Ola Hansson

Mol Cell Endocrinol 2016 07 1;430:138-45. Epub 2016 Feb 1.

Department of Clinical Sciences, CRC, Lund University, Malmö, 20502, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2016.01.027DOI Listing
July 2016

Myocardin Family Members Drive Formation of Caveolae.

Authors:
Katarzyna K Krawczyk Ingrid Yao Mattisson Mari Ekman Nikolay Oskolkov Rebecka Grantinge Dorota Kotowska Björn Olde Ola Hansson Sebastian Albinsson Joseph M Miano Catarina Rippe Karl Swärd

PLoS One 2015 5;10(8):e0133931. Epub 2015 Aug 5.

Department of Experimental Medical Science, BMC D12, Lund University, Lund, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0133931PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526231PMC
May 2016

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene.

Authors:
Joshua W Knowles Weijia Xie Zhongyang Zhang Indumathi Chennamsetty Themistocles L Assimes Jussi Paananen Ola Hansson James Pankow Mark O Goodarzi Ivan Carcamo-Orive Andrew P Morris Yii-Der I Chen Ville-Petteri Mäkinen Andrea Ganna Anubha Mahajan Xiuqing Guo Fahim Abbasi Danielle M Greenawalt Pek Lum Cliona Molony Lars Lind Cecilia Lindgren Leslie J Raffel Philip S Tsao Eric E Schadt Jerome I Rotter Alan Sinaiko Gerald Reaven Xia Yang Chao A Hsiung Leif Groop Heather J Cordell Markku Laakso Ke Hao Erik Ingelsson Timothy M Frayling Michael N Weedon Mark Walker Thomas Quertermous

J Clin Invest 2016 Jan 4;126(1):403. Epub 2016 Jan 4.

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http://dx.doi.org/10.1172/JCI85921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701558PMC
January 2016

A novel atlas of gene expression in human skeletal muscle reveals molecular changes associated with aging.

Authors:
Jing Su Carl Ekman Nikolay Oskolkov Leo Lahti Kristoffer Ström Alvis Brazma Leif Groop Johan Rung Ola Hansson

Skelet Muscle 2015 9;5:35. Epub 2015 Oct 9.

Lund University Diabetes Center, Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital Malmö, Lund University, Malmö, 20502 Sweden.

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http://www.skeletalmusclejournal.com/content/5/1/35
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http://dx.doi.org/10.1186/s13395-015-0059-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600214PMC
October 2015

Photocoagulation of human retinal pigment epithelium in vitro: unravelling the effects on ARPE-19 by transcriptomics and proteomics.

Authors:
Poya Tababat-Khani Carolina de la Torre Francesc Canals Hedvig Bennet Rafael Simo Cristina Hernandez Malin Fex Carl-David Agardh Ola Hansson Elisabet Agardh

Acta Ophthalmol 2015 Jun 21;93(4):348-54. Epub 2015 Jan 21.

Unit on Vascular Diabetic Complications, Department of Clinical Sciences, Lund University Diabetes Center, Malmö, Sweden.

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http://dx.doi.org/10.1111/aos.12649DOI Listing
June 2015

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene.

Authors:
Joshua W Knowles Weijia Xie Zhongyang Zhang Indumathi Chennamsetty Indumathi Chennemsetty Themistocles L Assimes Jussi Paananen Ola Hansson James Pankow Mark O Goodarzi Ivan Carcamo-Orive Andrew P Morris Yii-Der I Chen Ville-Petteri Mäkinen Andrea Ganna Anubha Mahajan Xiuqing Guo Fahim Abbasi Danielle M Greenawalt Pek Lum Cliona Molony Lars Lind Cecilia Lindgren Leslie J Raffel Philip S Tsao Eric E Schadt Jerome I Rotter Alan Sinaiko Gerald Reaven Xia Yang Chao A Hsiung Leif Groop Heather J Cordell Markku Laakso Ke Hao Erik Ingelsson Timothy M Frayling Michael N Weedon Mark Walker Thomas Quertermous

J Clin Invest 2015 Apr 23;125(4):1739-51. Epub 2015 Mar 23.

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http://dx.doi.org/10.1172/JCI74692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409020PMC
April 2015

TCF7L2 is a master regulator of insulin production and processing.

Authors:
Yuedan Zhou Soo-Young Park Jing Su Kathleen Bailey Emilia Ottosson-Laakso Liliya Shcherbina Nikolay Oskolkov Enming Zhang Thomas Thevenin João Fadista Hedvig Bennet Petter Vikman Nils Wierup Malin Fex Johan Rung Claes Wollheim Marcelo Nobrega Erik Renström Leif Groop Ola Hansson

Hum Mol Genet 2014 Dec 11;23(24):6419-31. Epub 2014 Jul 11.

Department of Clinical Sciences, CRC, Lund University, Malmö 20502, Sweden,

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddu359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240194PMC
December 2014

Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.

Authors:
João Fadista Petter Vikman Emilia Ottosson Laakso Inês Guerra Mollet Jonathan Lou Esguerra Jalal Taneera Petter Storm Peter Osmark Claes Ladenvall Rashmi B Prasad Karin B Hansson Francesca Finotello Kristina Uvebrant Jones K Ofori Barbara Di Camillo Ulrika Krus Corrado M Cilio Ola Hansson Lena Eliasson Anders H Rosengren Erik Renström Claes B Wollheim Leif Groop

Proc Natl Acad Sci U S A 2014 Sep 8;111(38):13924-9. Epub 2014 Sep 8.

Lund University Diabetes Centre, Department of Clinical Sciences, Skåne University Hospital Malmö, Lund University, 20502 Malmö, Sweden;

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http://dx.doi.org/10.1073/pnas.1402665111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183326PMC
September 2014

Exceptional evolutionary divergence of human muscle and brain metabolomes parallels human cognitive and physical uniqueness.

Authors:
Katarzyna Bozek Yuning Wei Zheng Yan Xiling Liu Jieyi Xiong Masahiro Sugimoto Masaru Tomita Svante Pääbo Raik Pieszek Chet C Sherwood Patrick R Hof John J Ely Dirk Steinhauser Lothar Willmitzer Jens Bangsbo Ola Hansson Josep Call Patrick Giavalisco Philipp Khaitovich

PLoS Biol 2014 May 27;12(5):e1001871. Epub 2014 May 27.

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai, China; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

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http://dx.doi.org/10.1371/journal.pbio.1001871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035273PMC
May 2014

A central role for GRB10 in regulation of islet function in man.

Authors:
Inga Prokopenko Wenny Poon Reedik Mägi Rashmi Prasad B S Albert Salehi Peter Almgren Peter Osmark Nabila Bouatia-Naji Nils Wierup Tove Fall Alena Stančáková Adam Barker Vasiliki Lagou Clive Osmond Weijia Xie Jari Lahti Anne U Jackson Yu-Ching Cheng Jie Liu Jeffrey R O'Connell Paul A Blomstedt Joao Fadista Sami Alkayyali Tasnim Dayeh Emma Ahlqvist Jalal Taneera Cecile Lecoeur Ashish Kumar Ola Hansson Karin Hansson Benjamin F Voight Hyun Min Kang Claire Levy-Marchal Vincent Vatin Aarno Palotie Ann-Christine Syvänen Andrea Mari Michael N Weedon Ruth J F Loos Ken K Ong Peter Nilsson Bo Isomaa Tiinamaija Tuomi Nicholas J Wareham Michael Stumvoll Elisabeth Widen Timo A Lakka Claudia Langenberg Anke Tönjes Rainer Rauramaa Johanna Kuusisto Timothy M Frayling Philippe Froguel Mark Walker Johan G Eriksson Charlotte Ling Peter Kovacs Erik Ingelsson Mark I McCarthy Alan R Shuldiner Kristi D Silver Markku Laakso Leif Groop Valeriya Lyssenko

PLoS Genet 2014 Apr 3;10(4):e1004235. Epub 2014 Apr 3.

Department of Clinical Science, Diabetes & Endocrinology, Lund University Diabetes Centre, Malmö, Sweden; Steno Diabetes Center A/S, Gentofte, Denmark.

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http://dx.doi.org/10.1371/journal.pgen.1004235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974640PMC
April 2014

Expression of phosphofructokinase in skeletal muscle is influenced by genetic variation and associated with insulin sensitivity.

Authors:
Sarah Keildson Joao Fadista Claes Ladenvall Åsa K Hedman Targ Elgzyri Kerrin S Small Elin Grundberg Alexandra C Nica Daniel Glass J Brent Richards Amy Barrett James Nisbet Hou-Feng Zheng Tina Rönn Kristoffer Ström Karl-Fredrik Eriksson Inga Prokopenko Timothy D Spector Emmanouil T Dermitzakis Panos Deloukas Mark I McCarthy Johan Rung Leif Groop Paul W Franks Cecilia M Lindgren Ola Hansson

Diabetes 2014 Mar 4;63(3):1154-65. Epub 2013 Dec 4.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.

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http://dx.doi.org/10.2337/db13-1301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931395PMC
March 2014

Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms.

Authors:
Melina Claussnitzer Simon N Dankel Bernward Klocke Harald Grallert Viktoria Glunk Tea Berulava Heekyoung Lee Nikolay Oskolkov Joao Fadista Kerstin Ehlers Simone Wahl Christoph Hoffmann Kun Qian Tina Rönn Helene Riess Martina Müller-Nurasyid Nancy Bretschneider Timm Schroeder Thomas Skurk Bernhard Horsthemke Derek Spieler Martin Klingenspor Martin Seifert Michael J Kern Niklas Mejhert Ingrid Dahlman Ola Hansson Stefanie M Hauck Matthias Blüher Peter Arner Leif Groop Thomas Illig Karsten Suhre Yi-Hsiang Hsu Gunnar Mellgren Hans Hauner Helmut Laumen

Cell 2014 Jan;156(1-2):343-58

Chair of Nutritional Medicine, Technische Universität München, Else Kröner-Fresenius-Center for Nutritional Medicine, 85350 Freising-Weihenstephan, Germany; Nutritional Medicine Unit, ZIEL-Research Center for Nutrition and Food Sciences, Technische Universität München, 85350 Freising-Weihenstephan, Germany; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany; Clinical Cooperation Group Nutrigenomics and Type 2 Diabetes, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany and Technische Universität München, 85350 Freising-Weihenstephan, Germany; Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg 85764, Germany. Electronic address:

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http://www.cell.com/cms/attachment/2021778258/2041667086/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S009286741301535
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http://dx.doi.org/10.1016/j.cell.2013.10.058DOI Listing
January 2014

Link between GIP and osteopontin in adipose tissue and insulin resistance.

Authors:
Emma Ahlqvist Peter Osmark Tiina Kuulasmaa Kasper Pilgaard Bilal Omar Charlotte Brøns Olga Kotova Anna V Zetterqvist Alena Stancáková Anna Jonsson Ola Hansson Johanna Kuusisto Timothy J Kieffer Tiinamaija Tuomi Bo Isomaa Sten Madsbad Maria F Gomez Pernille Poulsen Markku Laakso Eva Degerman Jussi Pihlajamäki Nils Wierup Allan Vaag Leif Groop Valeriya Lyssenko

Diabetes 2013 Jun 24;62(6):2088-94. Epub 2013 Jan 24.

Department of Clinical Sciences, Diabetes, and Endocrinology, University Hospital Malmö, Lund University, Malmö, Sweden.

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http://diabetes.diabetesjournals.org/content/62/6/2088.full.
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http://diabetes.diabetesjournals.org/content/early/2013/01/1
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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/db12-09
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http://dx.doi.org/10.2337/db12-0976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661641PMC
June 2013

PP038. Renal ETK/BMX activation decreased in preeclampsia.

Authors:
Helena Strevens Dag Wide-Swensson Ola Hansson Olle Melander

Pregnancy Hypertens 2013 Apr 6;3(2):80. Epub 2013 Jun 6.

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http://dx.doi.org/10.1016/j.preghy.2013.04.065DOI Listing
April 2013

Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes.

Authors:
Marloes Dekker Nitert Tasnim Dayeh Peter Volkov Targ Elgzyri Elin Hall Emma Nilsson Beatrice T Yang Stefan Lang Hemang Parikh Ylva Wessman Holger Weishaupt Joanne Attema Mia Abels Nils Wierup Peter Almgren Per-Anders Jansson Tina Rönn Ola Hansson Karl-Fredrik Eriksson Leif Groop Charlotte Ling

Diabetes 2012 Dec 1;61(12):3322-32. Epub 2012 Oct 1.

Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, CRC, Scania University Hospital, Malmö, Sweden.

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http://dx.doi.org/10.2337/db11-1653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501844PMC
December 2012

The triglyceride content in skeletal muscle is associated with hepatic but not peripheral insulin resistance in elderly twins.

Authors:
Louise Groth Grunnet Esa Laurila Ola Hansson Peter Almgren Leif Groop Charlotte Brøns Pernille Poulsen Allan Vaag

J Clin Endocrinol Metab 2012 Dec 9;97(12):4571-7. Epub 2012 Oct 9.

Department of Endocrinology, Diabetes, and Metabolism, Rigshospitalet, Tagensvej 20, 2200 Copenhagen, Denmark.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2012-2061DOI Listing
December 2012

Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.

Authors:
Taman Mahdi Sonja Hänzelmann Albert Salehi Sarheed J Muhammed Thomas M Reinbothe Yunzhao Tang Annika S Axelsson Yuedan Zhou Xingjun Jing Peter Almgren Ulrika Krus Jalal Taneera Anna M Blom Valeriya Lyssenko Jonathan Lou S Esguerra Ola Hansson Lena Eliasson Jonathan Derry Enming Zhang Claes B Wollheim Leif Groop Erik Renström Anders H Rosengren

Cell Metab 2012 Nov;16(5):625-33

Lund University Diabetes Centre, Lund University, 20502 Malmö, Sweden.

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http://dx.doi.org/10.1016/j.cmet.2012.10.009DOI Listing
November 2012

HTR1A a novel type 1 diabetes susceptibility gene on chromosome 5p13-q13.

Authors:
Samina Asad Pernilla Nikamo Alexandra Gyllenberg Hedvig Bennet Ola Hansson Nils Wierup Annelie Carlsson Gun Forsander Sten-Anders Ivarsson Helena Larsson Åke Lernmark Bengt Lindblad Johnny Ludvigsson Claude Marcus Kjersti S Rønningen Jan Nerup Flemming Pociot Holger Luthman Malin Fex Ingrid Kockum

PLoS One 2012 1;7(5):e35439. Epub 2012 May 1.

Neuroimmunology Unit, Department of Clinical Neurosciences, Karolinska Institutet, Stockholm, Sweden.

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https://www.diva-portal.org/smash/get/diva2:544401/FULLTEXT0
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http://dx.plos.org/10.1371/journal.pone.0035439
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035439PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341376PMC
September 2012

A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.

Authors:
Jalal Taneera Stefan Lang Amitabh Sharma Joao Fadista Yuedan Zhou Emma Ahlqvist Anna Jonsson Valeriya Lyssenko Petter Vikman Ola Hansson Hemang Parikh Olle Korsgren Arvind Soni Ulrika Krus Enming Zhang Xing-Jun Jing Jonathan L S Esguerra Claes B Wollheim Albert Salehi Anders Rosengren Erik Renström Leif Groop

Cell Metab 2012 Jul;16(1):122-34

Lund University Diabetes Center, Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital Malmö, Lund University, Malmö 20502, Sweden.

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http://dx.doi.org/10.1016/j.cmet.2012.06.006DOI Listing
July 2012

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

Authors:
Alisa K Manning Marie-France Hivert Robert A Scott Jonna L Grimsby Nabila Bouatia-Naji Han Chen Denis Rybin Ching-Ti Liu Lawrence F Bielak Inga Prokopenko Najaf Amin Daniel Barnes Gemma Cadby Jouke-Jan Hottenga Erik Ingelsson Anne U Jackson Toby Johnson Stavroula Kanoni Claes Ladenvall Vasiliki Lagou Jari Lahti Cecile Lecoeur Yongmei Liu Maria Teresa Martinez-Larrad May E Montasser Pau Navarro John R B Perry Laura J Rasmussen-Torvik Perttu Salo Naveed Sattar Dmitry Shungin Rona J Strawbridge Toshiko Tanaka Cornelia M van Duijn Ping An Mariza de Andrade Jeanette S Andrews Thor Aspelund Mustafa Atalay Yurii Aulchenko Beverley Balkau Stefania Bandinelli Jacques S Beckmann John P Beilby Claire Bellis Richard N Bergman John Blangero Mladen Boban Michael Boehnke Eric Boerwinkle Lori L Bonnycastle Dorret I Boomsma Ingrid B Borecki Yvonne Böttcher Claude Bouchard Eric Brunner Danijela Budimir Harry Campbell Olga Carlson Peter S Chines Robert Clarke Francis S Collins Arturo Corbatón-Anchuelo David Couper Ulf de Faire George V Dedoussis Panos Deloukas Maria Dimitriou Josephine M Egan Gudny Eiriksdottir Michael R Erdos Johan G Eriksson Elodie Eury Luigi Ferrucci Ian Ford Nita G Forouhi Caroline S Fox Maria Grazia Franzosi Paul W Franks Timothy M Frayling Philippe Froguel Pilar Galan Eco de Geus Bruna Gigante Nicole L Glazer Anuj Goel Leif Groop Vilmundur Gudnason Göran Hallmans Anders Hamsten Ola Hansson Tamara B Harris Caroline Hayward Simon Heath Serge Hercberg Andrew A Hicks Aroon Hingorani Albert Hofman Jennie Hui Joseph Hung Marjo-Riitta Jarvelin Min A Jhun Paul C D Johnson J Wouter Jukema Antti Jula W H Kao Jaakko Kaprio Sharon L R Kardia Sirkka Keinanen-Kiukaanniemi Mika Kivimaki Ivana Kolcic Peter Kovacs Meena Kumari Johanna Kuusisto Kirsten Ohm Kyvik Markku Laakso Timo Lakka Lars Lannfelt G Mark Lathrop Lenore J Launer Karin Leander Guo Li Lars Lind Jaana Lindstrom Stéphane Lobbens Ruth J F Loos Jian'an Luan Valeriya Lyssenko Reedik Mägi Patrik K E Magnusson Michael Marmot Pierre Meneton Karen L Mohlke Vincent Mooser Mario A Morken Iva Miljkovic Narisu Narisu Jeff O'Connell Ken K Ong Ben A Oostra Lyle J Palmer Aarno Palotie James S Pankow John F Peden Nancy L Pedersen Marina Pehlic Leena Peltonen Brenda Penninx Marijana Pericic Markus Perola Louis Perusse Patricia A Peyser Ozren Polasek Peter P Pramstaller Michael A Province Katri Räikkönen Rainer Rauramaa Emil Rehnberg Ken Rice Jerome I Rotter Igor Rudan Aimo Ruokonen Timo Saaristo Maria Sabater-Lleal Veikko Salomaa David B Savage Richa Saxena Peter Schwarz Udo Seedorf Bengt Sennblad Manuel Serrano-Rios Alan R Shuldiner Eric J G Sijbrands David S Siscovick Johannes H Smit Kerrin S Small Nicholas L Smith Albert Vernon Smith Alena Stančáková Kathleen Stirrups Michael Stumvoll Yan V Sun Amy J Swift Anke Tönjes Jaakko Tuomilehto Stella Trompet Andre G Uitterlinden Matti Uusitupa Max Vikström Veronique Vitart Marie-Claude Vohl Benjamin F Voight Peter Vollenweider Gerard Waeber Dawn M Waterworth Hugh Watkins Eleanor Wheeler Elisabeth Widen Sarah H Wild Sara M Willems Gonneke Willemsen James F Wilson Jacqueline C M Witteman Alan F Wright Hanieh Yaghootkar Diana Zelenika Tatijana Zemunik Lina Zgaga Nicholas J Wareham Mark I McCarthy Ines Barroso Richard M Watanabe Jose C Florez Josée Dupuis James B Meigs Claudia Langenberg

Nat Genet 2012 May 13;44(6):659-69. Epub 2012 May 13.

Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.2274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613127PMC
May 2012

Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway.

Authors:
Yuedan Zhou Enming Zhang Christine Berggreen Xingjun Jing Peter Osmark Stefan Lang Corrado M Cilio Olga Göransson Leif Groop Erik Renström Ola Hansson

Hum Mol Genet 2012 Jan 30;21(1):196-207. Epub 2011 Sep 30.

Department of Clinical Sciences, CRC, Lund University, Malmö 20502, Sweden.

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http://dx.doi.org/10.1093/hmg/ddr454DOI Listing
January 2012

Pleiotropic effects of GIP on islet function involve osteopontin.

Authors:
Valeriya Lyssenko Lena Eliasson Olga Kotova Kasper Pilgaard Nils Wierup Albert Salehi Anna Wendt Anna Jonsson Yang Z De Marinis Lisa M Berglund Jalal Taneera Alexander Balhuizen Ola Hansson Peter Osmark Pontus Dunér Charlotte Brøns Alena Stancáková Johanna Kuusisto Marco Bugliani Richa Saxena Emma Ahlqvist Timothy J Kieffer Tiinamaija Tuomi Bo Isomaa Olle Melander Emily Sonestedt Marju Orho-Melander Peter Nilsson Sara Bonetti Riccardo Bonadonna Roberto Miccoli Stefano Delprato Piero Marchetti Sten Madsbad Pernille Poulsen Allan Vaag Markku Laakso Maria F Gomez Leif Groop

Diabetes 2011 Sep 1;60(9):2424-33. Epub 2011 Aug 1.

Diabetes and Endocrinology, Department of Clinical Sciences, University Hospital Malmö, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.2337/db10-1532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161325PMC
September 2011

The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes.

Authors:
Anders H Olsson Tina Rönn Tarq Elgzyri Ola Hansson Karl-Fredrik Eriksson Leif Groop Allan Vaag Pernille Poulsen Charlotte Ling

Mol Genet Metab 2011 Jul 21;103(3):275-81. Epub 2011 Mar 21.

Lund University, Department of Clinical Sciences Malmö, Lund University Diabetes Centre, Scania University Hospital, Malmö, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S109671921100093
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http://dx.doi.org/10.1016/j.ymgme.2011.03.017DOI Listing
July 2011

Running with regulation.

Authors:
Ola Hansson

J Appl Physiol (1985) 2011 Jan 11;110(1):13-4. Epub 2010 Nov 11.

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http://www.physiology.org/doi/10.1152/japplphysiol.01327.201
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http://dx.doi.org/10.1152/japplphysiol.01327.2010DOI Listing
January 2011

Relation between cycling exercise capacity, fiber-type composition, and lower extremity muscle strength and muscle endurance.

Authors:
Asa B Segerström Anna M Holmbäck Ola Hansson Targ Elgzyri Karl-Fredrik Eriksson Karin Ringsberg Leif Groop Per Wollmer Ola Thorsson

J Strength Cond Res 2011 Jan;25(1):16-22

Department of Health Sciences, Division of Physiotherapy, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1519/JSC.0b013e31820238c5DOI Listing
January 2011

Molecular function of TCF7L2: Consequences of TCF7L2 splicing for molecular function and risk for type 2 diabetes.

Authors:
Ola Hansson Yuedan Zhou Erik Renström Peter Osmark

Curr Diab Rep 2010 Dec;10(6):444-51

Department of Clinical Sciences, CRC, Malmö University Hospital, Lund University, Malmö, Sweden.

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http://link.springer.com/10.1007/s11892-010-0149-8
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http://dx.doi.org/10.1007/s11892-010-0149-8DOI Listing
December 2010

Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes.

Authors:
Anders H Rosengren Ramunas Jokubka Damon Tojjar Charlotte Granhall Ola Hansson Dai-Qing Li Vini Nagaraj Thomas M Reinbothe Jonatan Tuncel Lena Eliasson Leif Groop Patrik Rorsman Albert Salehi Valeriya Lyssenko Holger Luthman Erik Renström

Science 2010 Jan 19;327(5962):217-20. Epub 2009 Nov 19.

Lund University Diabetes Centre, Malmö, SE-20502 Malmö, Sweden.

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http://dx.doi.org/10.1126/science.1176827DOI Listing
January 2010

Tissue-specific alternative splicing of TCF7L2.

Authors:
Ludmila Prokunina-Olsson Cullan Welch Ola Hansson Neeta Adhikari Laura J Scott Nicolle Usher Maurine Tong Andrew Sprau Amy Swift Lori L Bonnycastle Michael R Erdos Zhi He Richa Saxena Brennan Harmon Olga Kotova Eric P Hoffman David Altshuler Leif Groop Michael Boehnke Francis S Collins Jennifer L Hall

Hum Mol Genet 2009 Oct 14;18(20):3795-804. Epub 2009 Jul 14.

Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/hmg/ddp321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748888PMC
October 2009

Hormone-sensitive lipase (HSL) is also a retinyl ester hydrolase: evidence from mice lacking HSL.

Authors:
Kristoffer Ström Thomas E Gundersen Ola Hansson Stéphanie Lucas Céline Fernandez Rune Blomhoff Cecilia Holm

FASEB J 2009 Jul 26;23(7):2307-16. Epub 2009 Feb 26.

Division of Diabetes, Metabolism and Endocrinology, Department of Experimental Medical Science, Lund University, BMC C11, SE-221 84 Lund, Sweden.

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http://www.fasebj.org/content/early/2009/02/26/fj.08-120923.
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http://www.fasebj.org/cgi/doi/10.1096/fj.08-120923
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http://dx.doi.org/10.1096/fj.08-120923DOI Listing
July 2009

Hormone-sensitive lipase is necessary for normal mobilization of lipids during submaximal exercise.

Authors:
Céline Fernandez Ola Hansson Pernilla Nevsten Cecilia Holm Cecilia Klint

Am J Physiol Endocrinol Metab 2008 Jul 20;295(1):E179-86. Epub 2008 May 20.

Department of Experimental Medical Science, Lund University, BMC C11, SE-221 84 Lund, Sweden.

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http://dx.doi.org/10.1152/ajpendo.00282.2007DOI Listing
July 2008

Proteomic studies in animal models of diabetes.

Authors:
Svante Resjö Karin Berger Malin Fex Ola Hansson

Proteomics Clin Appl 2008 May 9;2(5):654-69. Epub 2008 Apr 9.

Department of Experimental Medical Science, Lund University, BMC C11, Lund, Sweden.

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http://dx.doi.org/10.1002/prca.200780030DOI Listing
May 2008

Attainment of brown adipocyte features in white adipocytes of hormone-sensitive lipase null mice.

Authors:
Kristoffer Ström Ola Hansson Stéphanie Lucas Pernilla Nevsten Céline Fernandez Cecilia Klint Sofia Movérare-Skrtic Frank Sundler Claes Ohlsson Cecilia Holm

PLoS One 2008 Mar 12;3(3):e1793. Epub 2008 Mar 12.

Department of Experimental Medical Science, Lund University, Lund, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0001793PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258419PMC
March 2008

Inflammatory response in white adipose tissue in the non-obese hormone-sensitive lipase null mouse model.

Authors:
Ola Hansson Kristoffer Ström Nuray Güner Nils Wierup Frank Sundler Peter Höglund Cecilia Holm

J Proteome Res 2006 Jul;5(7):1701-10

Department of Experimental Medical Science, Lund University, BMC C11, SE-221 84 Lund, Sweden.

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http://pubs.acs.org/doi/abs/10.1021/pr060101h
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http://dx.doi.org/10.1021/pr060101hDOI Listing
July 2006

Transcriptome and proteome analysis of soleus muscle of hormone-sensitive lipase-null mice.

Authors:
Ola Hansson Morten Donsmark Charlotte Ling Pernilla Nevsten Mikael Danfelter Jesper L Andersen Henrik Galbo Cecilia Holm

J Lipid Res 2005 Dec 30;46(12):2614-23. Epub 2005 Sep 30.

Department of Experimental Medical Science, Lund University, Lund, Sweden.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M500028-JLR200
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http://dx.doi.org/10.1194/jlr.M500028-JLR200DOI Listing
December 2005

[Serotonin syndrome--several cases of this often overlooked diagnosis].

Authors:
Jonas Höjer Mark Personne Ann-Sofi Skagius Ola Hansson

Tidsskr Nor Laegeforen 2002 Jun;122(17):1660-3

Giftinformationscentralen SE-171 76 Stockholm.

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June 2002

[Serotonin syndrome. Several cases of this often overlooked diagnosis].

Authors:
Jonas Höjer Mark Personne Ann-Sofi Skagius Ola Hansson

Lakartidningen 2002 May;99(18):2054-5, 2058-60

Giftinformationscentralen, Stockholm.

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May 2002