Oksana Palyha

Oksana Palyha

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Oksana Palyha

Oksana Palyha

Publications by authors named "Oksana Palyha"

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Discovery and Pharmacology of a Novel Class of Diacylglycerol Acyltransferase 2 Inhibitors.

J Med Chem 2015 Dec 20;58(23):9345-53. Epub 2015 Nov 20.

Department of Discovery Chemistry, ‡Chemistry Modeling, and Informatics, §In Vitro Pharmacology, ∥In Vivo Pharmacology, ⊥Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, #Basic Pharmaceutical Sciences, and ○Atherosclerosis, Merck & Co., Inc. , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.

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http://dx.doi.org/10.1021/acs.jmedchem.5b01345DOI Listing
December 2015

Utilizing HaloTag Technology to Track the Fate of PCSK9 from Intracellular vs. Extracellular Sources.

Curr Chem Genomics 2012 20;6:38-47. Epub 2012 Sep 20.

Department of Atherosclerosis, Merck Research Laboratories, Rahway, NJ 07065, USA.

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http://dx.doi.org/10.2174/1875397301206010038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480691PMC
November 2012

Discovery of a new role of human resistin in hepatocyte low-density lipoprotein receptor suppression mediated in part by proprotein convertase subtilisin/kexin type 9.

J Am Coll Cardiol 2012 May;59(19):1697-705

Department of Medicine, Thrombosis and Atherosclerosis Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, McMaster University, Hamilton, Ontario, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S073510971200635
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http://dx.doi.org/10.1016/j.jacc.2011.11.064DOI Listing
May 2012

Pyridinesulfonylureas and pyridinesulfonamides as selective bombesin receptor subtype-3 (BRS-3) agonists.

Bioorg Med Chem Lett 2011 Apr 25;21(7):2040-3. Epub 2011 Feb 25.

Department of Medicinal Chemistry, Merck Research Laboratories, Rahway, NJ 07065, USA.

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http://dx.doi.org/10.1016/j.bmcl.2011.02.011DOI Listing
April 2011

4-Aminoquinoline melanin-concentrating hormone 1-receptor (MCH1R) antagonists.

Bioorg Med Chem Lett 2006 Oct 17;16(20):5275-9. Epub 2006 Aug 17.

Department of Medicinal Chemistry, Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065-0900, USA.

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http://dx.doi.org/10.1016/j.bmcl.2006.08.008DOI Listing
October 2006