Okezie I Aruoma

Okezie I Aruoma

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Okezie I Aruoma

Okezie I Aruoma

Publications by authors named "Okezie I Aruoma"

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68Publications

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Fermented papaya preparation modulates the progression of N-methyl-N-nitrosourea induced hepatocellular carcinoma in Balb/c mice.

Life Sci 2016 Apr 12;151:330-338. Epub 2016 Mar 12.

ANDI Centre of Excellence for Biomedical and Biomaterials Research, MSIRI Building, Faculty of Science, University of Mauritius, Réduit, Mauritius. Electronic address:

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April 2016

Oxidative stress in aging.

Oxid Med Cell Longev 2014 6;2014:876834. Epub 2014 Apr 6.

Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran 1417614411, Iran.

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December 2014

Diabetes as a risk factor to cancer: functional role of fermented papaya preparation as phytonutraceutical adjunct in the treatment of diabetes and cancer.

Mutat Res 2014 Oct 24;768:60-8. Epub 2014 Apr 24.

ANDI Center for Biomedical and Biomaterials Research, University of Mauritius, MSIRI Building, Réduit, Mauritius. Electronic address:

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October 2014

Cancer risks and perspectives: molecular mechanisms.

Mutat Res 2014 Oct;768:1-5

SSR Medical College, Mauritius.

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October 2014

Mechanistic perspectives on cancer chemoprevention/chemotherapeutic effects of thymoquinone.

Mutat Res 2014 Oct 27;768:22-34. Epub 2014 May 27.

College of Pharmacy, Keimyung University, Daegu 704 701, Republic of Korea. Electronic address:

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October 2014

Effectiveness of green tea in a randomized human cohort: relevance to diabetes and its complications.

Biomed Res Int 2013 12;2013:412379. Epub 2013 Sep 12.

ANDI Centre of Excellence for Biomedical and Biomaterials Research and Department of Biosciences University of Mauritius, Réduit, Mauritius.

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June 2014

Relationship between fermented papaya preparation supplementation, erythrocyte integrity and antioxidant status in pre-diabetics.

Food Chem Toxicol 2014 Mar 5;65:12-7. Epub 2013 Dec 5.

School of Pharmacy, American University of Health Sciences, Signal Hill, CA 90755, USA. Electronic address:

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March 2014

Effect of Aegle marmelos leaf extract on N-methyl N-nitrosourea-induced hepatocarcinogensis in Balb/c mice.

Pharm Biol 2013 Oct 16;51(10):1272-81. Epub 2013 Jul 16.

School of Biotechnology, Faculty of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

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October 2013

The effect of black tea on risk factors of cardiovascular disease in a normal population.

Prev Med 2012 May 16;54 Suppl:S98-102. Epub 2011 Dec 16.

ANDI Centre of Excellence for Biomedical and Biomaterials Research, CBBR Building, MSIRI, University of Mauritius, Réduit, Republic of Mauritius.

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May 2012

Effects of a short term supplementation of a fermented papaya preparation on biomarkers of diabetes mellitus in a randomized Mauritian population.

Prev Med 2012 May 11;54 Suppl:S90-7. Epub 2012 Feb 11.

ANDI Centre of Excellence for Biomedical and Biomaterials Research and Department of Biosciences University of Mauritius, Réduit, Republic of Mauritius.

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May 2012

Functional benefits of citrus fruits in the management of diabetes.

Prev Med 2012 May 25;54 Suppl:S12-6. Epub 2012 Feb 25.

School of Biomedical Sciences and School of Pharmacy, American University of Health Sciences, Signal Hill, CA 90755, USA.

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May 2012

Functional benefits of ergothioneine and fruit- and vegetable-derived nutraceuticals: overview of the supplemental issue contents.

Prev Med 2012 May;54 Suppl:S4-8

School of Pharmacy and Biomedical Sciences, American University of Health Sciences, Signal Hill, CA 90755, USA.

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May 2012

The effect of ergothioneine on clastogenic potential and mutagenic activity: genotoxicity evaluation.

Int J Toxicol 2011 Aug 19;30(4):405-9. Epub 2011 Jul 19.

Natural and Medicine Products Research, AIBMR Life Sciences, Puyallup, WA 98373, USA.

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August 2011

Targeting specific cell signaling transduction pathways by dietary and medicinal phytochemicals in cancer chemoprevention.

Toxicology 2010 Dec 20;278(2):229-41. Epub 2009 Oct 20.

Department of Health Sciences, Faculty of Science, University of Mauritius, Réduit, Mauritius.

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December 2010

The future of biomarkers.

Toxicology 2010 Dec 1;278(2):161-4. Epub 2010 Oct 1.

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December 2010

Effect of an antioxidant functional food beverage on exercise-induced oxidative stress: a long-term and large-scale clinical intervention study.

Toxicology 2010 Nov 24;278(1):101-11. Epub 2009 Oct 24.

Department of Physiology & Pharmacology, Campus M. Unamuno, University of Salamanca, E-37007 Salamanca, Spain.

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November 2010

Bioactive phenolics and antioxidant propensity of flavedo extracts of Mauritian citrus fruits: potential prophylactic ingredients for functional foods application.

Toxicology 2010 Nov 25;278(1):75-87. Epub 2010 Jan 25.

Department of Agricultural and Food Science, Faculty of Agriculture, University of Mauritius, Réduit, Mauritius.

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November 2010

Applications and bioefficacy of the functional food supplement fermented papaya preparation.

Toxicology 2010 Nov 24;278(1):6-16. Epub 2010 Sep 24.

Department of Pharmaceutical and Biomedical Sciences, Touro College of Pharmacy, New York, NY, USA.

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November 2010

Functional nutraceuticals.

Authors:
Okezie I Aruoma

Toxicology 2010 Nov 29;278(1):2-5. Epub 2010 Sep 29.

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November 2010

Aspects of antioxidant foods and supplements in health and disease.

Nutr Rev 2009 May;67 Suppl 1:S140-4

Department of Biochemistry and Molecular Biology, Universidad San Pablo - CEU, Madrid, Spain.

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May 2009

Modulation of experimental osteoporosis in rats by the antioxidant beverage effective microorganism-X (EM-X).

Biomed Pharmacother 2009 Feb 16;63(2):114-9. Epub 2008 Apr 16.

EM Research Organization, 468 Kawasaki Uruma City, Okinawa 904-2203, Japan.

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February 2009

Acute and chronic effects of intravitreally injected beta-amyloid on the neurotransmitter system in the retina.

Toxicology 2009 Feb 19;256(1-2):92-100. Epub 2008 Nov 19.

Department of Pharmaceutical and Biomedical Sciences, Touro College of Pharmacy, New York, NY 10027, USA.

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February 2009

Induction of apoptosis in MCF-7 and MDA-MB-231 breast cancer cells by Oligonol is mediated by Bcl-2 family regulation and MEK/ERK signaling.

Eur J Cancer Prev 2007 Aug;16(4):342-7

Laboratory of Stem Cell and Tumor Biology, Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University, Seoul, Korea.

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August 2007

Modulation of infection-induced inflammation and locomotive deficit and longevity in senescence-accelerated mice-prone (SAMP8) model by the oligomerized polyphenol Oligonol.

Biomed Pharmacother 2007 Aug 12;61(7):427-34. Epub 2007 Jun 12.

Amino Up Chemical Company, 363-32 Shin-ei, Kiyota-ku, Sapporo, 004-0839, Japan.

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August 2007

Short-term supplementation with plant extracts rich in flavonoids protect nigrostriatal dopaminergic neurons in a rat model of Parkinson's disease.

J Am Coll Nutr 2007 Aug;26(4):341-9

Department of Cellular and Molecular Neuroscience, Division of Neuroscience and Mental Health, Faculty of Medicine, Imperial College, Charing Cross Campus, St. Dunstan's Road, London W6 8RP, United Kingdom.

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August 2007

The influence of active hexose correlated compound (AHCC) on cisplatin-evoked chemotherapeutic and side effects in tumor-bearing mice.

Toxicol Appl Pharmacol 2007 Jul 20;222(2):152-8. Epub 2007 Apr 20.

Amino Up Chemical Company, 363-32 Shin-ei, Kiyota-ku, Sapporo 004-0839, Japan.

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July 2007

Free radicals in biology and medicine: from inflammation to biotechnology.

Biofactors 2006 ;27(1-4):1-3

Faculty of Health and Social Care, London South Bank University, 103 Borough Road, London, UK.

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March 2007

Chemopreventive actions of polyphenolic compounds in cancer.

Biofactors 2006 ;27(1-4):19-35

Department of Biosciences, Faculty of Science, University of Mauritius, Réduit, Republic of Mauritius.

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March 2007

Reversal of the TPA-induced inhibition of gap junctional intercellular communication by Chaga mushroom (Inonotus obliquus) extracts: effects on MAP kinases.

Biofactors 2006 ;27(1-4):147-55

Laboratory of Stem Cell and Tumor Biology, Department of Veterinary Public Health, College of Veterinary Medicine and BK 21 Program for Veterinary Science, Seoul National University, Sillim 9-dong, Gwanak-gu, Seoul 151-742, South Korea.

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March 2007

Activity of the dietary antioxidant ergothioneine in a virus gene-based assay for inhibitors of HIV transcription.

Biofactors 2006 ;27(1-4):157-65

Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, GA 30602, USA.

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March 2007

Evaluation of the safety and toxicity of the oligomerized polyphenol Oligonol.

Food Chem Toxicol 2007 Mar 16;45(3):378-87. Epub 2006 Sep 16.

Amino Up Chemical Company, 363-32 Shin-Ei, Sapporo, Japan.

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March 2007

Effects of the histone deacetylases inhibitors sodium butyrate and trichostatin A on the inhibition of gap junctional intercellular communication by H2O2- and 12-O-tetradecanoylphorbol-13-acetate in rat liver epithelial cells.

Cancer Lett 2006 Sep 5;241(2):301-8. Epub 2005 Dec 5.

Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University, San 56-1, Sillim-dong, Gwanakgu, Seoul 151-742, South Korea.

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September 2006

Comparative efficacy of oligonol, catechin and (-)-epigallocatechin 3-O-gallate in modulating the potassium bromate-induced renal toxicity in rats.

Toxicology 2006 Sep 7;226(2-3):181-7. Epub 2006 Jul 7.

Amino Up Chemical Co. Ltd., High Tech Hill Shin-ei, 363-32 Shin-ei, Kiyota, Sapporo 004-0839, Japan.

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September 2006

Characterization of the phenolic constituents in Mauritian endemic plants as determinants of their antioxidant activities in vitro.

J Plant Physiol 2006 Jul 25;163(8):787-99. Epub 2006 Jan 25.

Department of Biosciences, Faculty of Science, University of Mauritius, Réduit, Republic of Mauritius.

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July 2006

The impact of food regulation on the food supply chain.

Authors:
Okezie I Aruoma

Toxicology 2006 Apr 17;221(1):119-27. Epub 2006 Feb 17.

Faculty of Health and Social Care, London South Bank University, 103 Borough Road, London SE1 0AA, United Kingdom.

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April 2006

Modulation of hydrogen peroxide-induced DNA damage, MAPKs activation and cell death in PC12 by ergothioneine.

Clin Nutr 2006 Feb 28;25(1):135-45. Epub 2005 Nov 28.

Dip. Scienze dell'Uomo e dell'Ambiente, Università di Pisa, Sezione di Genetica Via S. Giuseppe 22, 56126 Pisa, Italy.

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February 2006

Molecular mechanisms of the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced inverted U-shaped dose responsiveness in anchorage independent growth and cell proliferation of human breast epithelial cells with stem cell characteristics.

Mutat Res 2005 Nov 26;579(1-2):189-99. Epub 2005 Jul 26.

Laboratory of Stem Cell and Tumor Biology, Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University, San 56-1 Sillim-Dong, Kwanak-Gu, Seoul 151-742, Republic of Korea.

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November 2005

Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease.

Free Radic Res 2005 Oct;39(10):1119-25

Imperial College London, Charing Cross Hospital, Faculty of Medicine, Department of Cellular and Molecular Neuroscience, Fulham Palace Road, London, W6 8RF, UK.

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October 2005

Evaluation of the toxicity and safety of the antioxidant beverage effective microorganisms-X (EM-X) in animal models.

Environ Toxicol Pharmacol 2005 Sep;20(2):313-20

EM Research Organization, 468 Kawasaki Uruma City Okinawa 904-2203, Japan.

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September 2005

L-ergothioneine modulates oxidative damage in the kidney and liver of rats in vivo: studies upon the profile of polyunsaturated fatty acids.

Clin Nutr 2004 Apr;23(2):183-93

Dipartimento di Biologia Sperimentale, Sezione Patologia Sperimentale, Università degli Studi di Cagliari, Cittadella Universitaria SS 554, 09042 Monserrato, Cagliari, Italy.

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April 2004

Uric acid and allantoin levels in Down syndrome: antioxidant and oxidative stress mechanisms?

Clin Chim Acta 2004 Mar;341(1-2):139-46

Institute of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Comenius University, Sasinkova 2, 813 72 Bratislava, Slovak Republic.

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March 2004

Ergothioneine rescues PC12 cells from beta-amyloid-induced apoptotic death.

Free Radic Biol Med 2004 Feb;36(3):288-99

Laboratory of Biochemistry and Molecular Toxicology, College of Pharmacy, Seoul National University, Seoul 151-742, South Korea.

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February 2004

Neuroprotection by bioactive components in medicinal and food plant extracts.

Mutat Res 2003 Nov;544(2-3):203-15

Department of Neuroinflammation, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College London, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK.

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November 2003

Effects of the phenolic contents of Mauritian endemic plant extracts on promoter activities of antioxidant enzymes.

Free Radic Res 2003 Nov;37(11):1215-24

Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.

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November 2003

Methodological considerations for characterizing potential antioxidant actions of bioactive components in plant foods.

Authors:
Okezie I Aruoma

Mutat Res 2003 Feb-Mar;523-524:9-20

Department of Neuroinflammation, Faculty of Medicine, Division of Neuroinflammation and Psychological Medicine, Imperial College London, Charing Cross Hospital Campus, Fulham Palace Road, London W6 8RF, UK.

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April 2003

Ergothioneine inhibits oxidative stress- and TNF-alpha-induced NF-kappa B activation and interleukin-8 release in alveolar epithelial cells.

Biochem Biophys Res Commun 2003 Mar;302(4):860-4

ELEGI and Colt Research Laboratory, Respiratory Medicine Unit, Wilkie Building, University of Edinburgh, Medical School, Teviot Place, Edinburgh EH8 9AG, UK.

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March 2003

The antioxidant cocktail, effective microorganism X (EM-X), protects retinal neurons in rats against N-methyl-D-aspartate excitotoxicity in vivo.

Free Radic Res 2003 Jan;37(1):91-7

Department of Neuroinflammation, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Charing Cross Hospital Campus, Fulham Palace Road, London W6 8RF, UK.

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January 2003

Assessment of the ability of the antioxidant cocktail-derived from fermentation of plants with effective microorganisms (EM-X) to modulate oxidative damage in the kidney and liver of rats in vivo: studies upon the profile of poly- and mono-unsaturated fatty acids.

Toxicol Lett 2002 Oct;135(3):209-17

Division of Neuroscience and Psychological Medicine, Department of Neuroinflammation, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Charing Cross Hospital Campus, Fulham Palace Road, London W6 8RF, UK.

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October 2002

The antioxidant cocktail effective microorganism X (EM-X) inhibits oxidant-induced interleukin-8 release and the peroxidation of phospholipids in vitro.

Biochem Biophys Res Commun 2002 Sep;296(5):1148-51

Dipartimento di Biologia Sperimentale, Sez. Patologia Sperimentale, Università degli Studi di Cagliari, Cittadella Universitaria SS 554, 09042 Monserrato, Cagliari, Italy.

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September 2002

Ergothioneine treatment protects neurons against N-methyl-D-aspartate excitotoxicity in an in vivo rat retinal model.

Neurosci Lett 2002 Aug;328(1):55-9

Department of Neuroinflammation, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK.

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August 2002

Antioxidant activities of phenolic, proanthocyanidin, and flavonoid components in extracts of Cassia fistula.

J Agric Food Chem 2002 Aug;50(18):5042-7

Department of Biological Sciences, Faculty of Science, University of Mauritius, Réduit, United Kingdom.

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August 2002