Ofir Cohen

Ofir Cohen

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Ofir Cohen

Ofir Cohen

Publications by authors named "Ofir Cohen"

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A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma.

Cancer Res 2019 May 28;79(9):2352-2366. Epub 2019 Feb 28.

Cancer Program, The Broad Institute of M.I.T. and Harvard, Cambridge, Massachusetts.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-2711DOI Listing
May 2019

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.

Cancer Cell 2018 12 21;34(6):939-953.e9. Epub 2018 Nov 21.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; Center for Cancer Evolution, Dana-Farber Cancer Institute, Boston, MA 02215, USA; The Eli and Edythe L Broad Institute of MIT and Harvard, Cambridge, MA 02139, USA; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Ludwig Center at Harvard, Boston, MA 02215, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15356108183048
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http://dx.doi.org/10.1016/j.ccell.2018.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310147PMC
December 2018

Real time quantitative analysis of lipid storage and lipolysis pathways by confocal spectral imaging of intracellular micropolarity.

Biochim Biophys Acta Mol Cell Biol Lipids 2018 07 11;1863(7):783-793. Epub 2018 Apr 11.

Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel.

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http://dx.doi.org/10.1016/j.bbalip.2018.04.004DOI Listing
July 2018

Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations.

Cancer Cell 2018 02;33(2):173-186.e5

Center for Functional Cancer Epigenetics, Dana Farber Cancer Institute, Boston, MA 02210, USA; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02210, USA; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02210, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813700PMC
February 2018

Comparative transcriptomics across the prokaryotic tree of life.

Nucleic Acids Res 2016 Jul 6;44(W1):W46-53. Epub 2016 May 6.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel

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http://dx.doi.org/10.1093/nar/gkw394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987935PMC
July 2016

Hormetic and regulatory effects of lipid peroxidation mediators in pancreatic beta cells.

Mol Aspects Med 2016 06 21;49:49-77. Epub 2016 Mar 21.

Department of Pharmacology, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2016.03.001DOI Listing
June 2016

Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.

Cell Rep 2016 Apr 14;15(4):857-865. Epub 2016 Apr 14.

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.03.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850357PMC
April 2016

Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires.

Nat Genet 2016 Feb 11;48(2):167-75. Epub 2016 Jan 11.

Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050043PMC
http://dx.doi.org/10.1038/ng.3481DOI Listing
February 2016

Beta cell response to nutrient overload involves phospholipid remodelling and lipid peroxidation.

Diabetologia 2015 Jun 26;58(6):1333-43. Epub 2015 Mar 26.

Department of Pharmacology, Institute for Drug Research, Faculty of Medicine, The Hebrew University, Jerusalem, 9112102, Israel.

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http://link.springer.com/content/pdf/10.1007/s00125-015-3566
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http://link.springer.com/10.1007/s00125-015-3566-z
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http://dx.doi.org/10.1007/s00125-015-3566-zDOI Listing
June 2015

Indel reliability in indel-based phylogenetic inference.

Genome Biol Evol 2014 Nov 18;6(12):3199-209. Epub 2014 Nov 18.

Department of Zoology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, Israel

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http://dx.doi.org/10.1093/gbe/evu252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986452PMC
November 2014

CoPAP: Coevolution of presence-absence patterns.

Nucleic Acids Res 2013 Jul 8;41(Web Server issue):W232-7. Epub 2013 Jun 8.

Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv 69978, Israel.

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http://dx.doi.org/10.1093/nar/gkt471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692100PMC
July 2013

Uncovering the co-evolutionary network among prokaryotic genes.

Bioinformatics 2012 Sep;28(18):i389-i394

Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1093/bioinformatics/bts396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436823PMC
September 2012

FastML: a web server for probabilistic reconstruction of ancestral sequences.

Nucleic Acids Res 2012 Jul 31;40(Web Server issue):W580-4. Epub 2012 May 31.

Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, 69978 Tel Aviv, Israel.

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http://dx.doi.org/10.1093/nar/gks498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394241PMC
July 2012

Inference of gain and loss events from phyletic patterns using stochastic mapping and maximum parsimony--a simulation study.

Genome Biol Evol 2011 4;3:1265-75. Epub 2011 Oct 4.

Department of Cell Research and Immunology, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1093/gbe/evr101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215202PMC
February 2012

The complexity hypothesis revisited: connectivity rather than function constitutes a barrier to horizontal gene transfer.

Mol Biol Evol 2011 Apr 13;28(4):1481-9. Epub 2010 Dec 13.

Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1093/molbev/msq333DOI Listing
April 2011

GLOOME: gain loss mapping engine.

Bioinformatics 2010 Nov 27;26(22):2914-5. Epub 2010 Sep 27.

Department of Cell Research and Immunology, Tel-Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1093/bioinformatics/btq549DOI Listing
November 2010

Inference and characterization of horizontally transferred gene families using stochastic mapping.

Mol Biol Evol 2010 Mar 6;27(3):703-13. Epub 2009 Oct 6.

Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1093/molbev/msp240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822287PMC
March 2010

Large-scale parsimony analysis of metazoan indels in protein-coding genes.

Mol Biol Evol 2010 Feb 28;27(2):441-51. Epub 2009 Oct 28.

Department of Zoology, Tel-Aviv University, Israel.

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http://dx.doi.org/10.1093/molbev/msp263DOI Listing
February 2010

A likelihood framework to analyse phyletic patterns.

Philos Trans R Soc Lond B Biol Sci 2008 Dec;363(1512):3903-11

Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1098/rstb.2008.0177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607420PMC
December 2008