Ofer Isakov

Ofer Isakov

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Ofer Isakov

Ofer Isakov

Publications by authors named "Ofer Isakov"

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Resection Versus Observation of Small Asymptomatic Nonfunctioning Pancreatic Neuroendocrine Tumors.

J Gastrointest Surg 2019 Jun 13. Epub 2019 Jun 13.

Unit of Liver Surgery Department of Surgery, Tel-Aviv Medical Center, Tel Aviv, Israel.

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http://dx.doi.org/10.1007/s11605-019-04285-yDOI Listing
June 2019

Prediction of Success in External Cephalic Version for Breech Presentation at Term.

Obstet Gynecol 2019 May;133(5):857-866

Department of Internal Medicine "T," Sourasky Medical Center, and the Department of Obstetrics and Gynecology, Lis Maternity Hospital, Sourasky Medical Center, Tel Aviv, Israel.

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http://dx.doi.org/10.1097/AOG.0000000000003196DOI Listing
May 2019

Variant in Central Centrifugal Cicatricial Alopecia.

N Engl J Med 2019 02 13;380(9):833-841. Epub 2019 Feb 13.

From the Department of Dermatology (L.M., O.S., A.P., M.P., E.W., L.S., V.B., J.M., E.S.) and the Institute of Pathology (A.G.), Tel Aviv Medical Center, the Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine (L.M., A.P., J.M., E.S.), and the Department of Cell and Developmental Biology (O.I., T.R., N.S.), Tel Aviv University, Tel Aviv, and the Schulich Faculty of Chemistry, Technion, Haifa (N.A.) - all in Israel; the Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany (M.-T.R., R.C.B.); L'Unité Différenciation Epitheliale et Autoimmunité Rhumatoïde (UDEAR), INSERM, Université Paul Sabatier, Université de Toulouse Midi-Pyrénées, Toulouse, France (M.-C.M., M.S.); the Department of Dermatology, Wake Forest Baptist Medical Center, Winston-Salem, NC (L.U., A.M.); and the Dermatology Department, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa (N.C.D).

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http://www.nejm.org/doi/10.1056/NEJMoa1816614
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http://dx.doi.org/10.1056/NEJMoa1816614DOI Listing
February 2019

Genotype-Serotype Interactions Shed Light on Genetic Components of Inflammatory Bowel Diseases.

Inflamm Bowel Dis 2019 01;25(2):336-344

IBD Center, Department of Gastroenterology and Liver Diseases.

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http://dx.doi.org/10.1093/ibd/izy231DOI Listing
January 2019

Neoadjuvant FOLFIRINOX for locally advanced and borderline resectable pancreatic cancer: An intention to treat analysis.

Eur J Surg Oncol 2018 10 2;44(10):1619-1623. Epub 2018 Aug 2.

Department of Surgery at the Tel-Aviv Medical Center, Sackler School of Medicine, The Nicholas and Elizabeth Cathedra of Experimental Surgery, Tel Aviv University, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.ejso.2018.07.057DOI Listing
October 2018

Exhaustive non-synonymous variants functionality prediction enables high resolution characterization of the neurofibromin architecture.

EBioMedicine 2018 Oct 28;36:508-516. Epub 2018 Sep 28.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Gilbert Israeli Neurofibromatosis Center, Tel-Aviv Medical Center, Tel-Aviv, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.09.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197713PMC
October 2018

Machine Learning-Based Gene Prioritization Identifies Novel Candidate Risk Genes for Inflammatory Bowel Disease.

Inflamm Bowel Dis 2017 09;23(9):1516-1523

*Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; †Department of Gastroenterology and Liver Diseases, IBD Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; and ‡Genetic Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

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http://dx.doi.org/10.1097/MIB.0000000000001222DOI Listing
September 2017

Epidermolytic Ichthyosis Sine Epidermolysis.

Am J Dermatopathol 2017 Jun;39(6):440-444

*Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; †Department of Human Molecular Genetics & Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; ‡Department of Dermatology, Kirov State Medical Academy, Kirov, Russia; §Department of Pathology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; ¶Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; ‖INSERM UMR 1163, Imagine Institute, University Paris Descartes Sorbonne Cité, Paris, France; **Department of Genetics, Necker hospital for sick children, APHP, Paris, France; ††Department of Dermatology and Allergology, Ludwig-Maximilian-University, Munich, Germany; and Departments of ‡‡Pathology, §§Dermatology, and ¶¶Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL.

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http://dx.doi.org/10.1097/DAD.0000000000000674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489912PMC
June 2017

X-linked elliptocytosis with impaired growth is related to mutated AMMECR1.

Gene 2017 Mar 9;606:47-52. Epub 2017 Jan 9.

Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2017.01.001DOI Listing
March 2017

Calpain 12 Function Revealed through the Study of an Atypical Case of Autosomal Recessive Congenital Ichthyosis.

J Invest Dermatol 2017 02 18;137(2):385-393. Epub 2016 Oct 18.

Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.07.043DOI Listing
February 2017

Whole-exome sequencing in individuals with multiple cardiovascular risk factors and normal coronary arteries.

Coron Artery Dis 2016 Jun;27(4):257-66

aDepartment of Cardiology, Tel-Aviv Medical Center, Sackler Faculty of Medicine bSusanne Levy Gertner Oncogenetics Unit, Danek Gertner Institute of Genetics, Chaim Sheba Medical Center, Sackler Faculty of Medicine cSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

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http://dx.doi.org/10.1097/MCA.0000000000000357DOI Listing
June 2016

Influence of population diversity on neurovirulence potential of plaque purified L-Zagreb variants.

Vaccine 2016 Apr 21;34(20):2383-9. Epub 2016 Mar 21.

Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2016.03.033DOI Listing
April 2016

Actionable clinical decisions based on comprehensive genomic evaluation in asymptomatic adults.

Mol Genet Genomic Med 2015 Sep 6;3(5):433-9. Epub 2015 May 6.

Faculty of Medicine, Tel Aviv University Tel Aviv, 69978, Israel.

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http://dx.doi.org/10.1002/mgg3.154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585451PMC
September 2015

Deep sequencing analysis of viral infection and evolution allows rapid and detailed characterization of viral mutant spectrum.

Bioinformatics 2015 Jul 19;31(13):2141-50. Epub 2015 Feb 19.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel, Institut Pasteur, Viral Populations and Pathogenesis, CNRS URA 3015, Paris, France and Department of Statistics and Operations Research, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1093/bioinformatics/btv101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481840PMC
July 2015

Rare genetic variants in Tunisian Jewish patients suffering from age-related macular degeneration.

J Med Genet 2015 Jul 18;52(7):484-92. Epub 2015 May 18.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Danek Gartener Institute of Human Genetics, Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1136/jmedgenet-2015-103130DOI Listing
July 2015

Mutations in coronavirus nonstructural protein 10 decrease virus replication fidelity.

J Virol 2015 Jun 8;89(12):6418-26. Epub 2015 Apr 8.

Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee, USA The Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee, USA Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee, USA

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http://dx.doi.org/10.1128/JVI.00110-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474304PMC
June 2015

Sequencing your genome: your future is here, but are you sure you want to know it?

Genet Res (Camb) 2014 ;96:e006

Faculty of Medicine,Tel Aviv University,Tel Aviv 69978,Israel.

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http://dx.doi.org/10.1017/S0016672314000093DOI Listing
April 2015

MicroRNA-mediated regulation of p21 and TASK1 cellular restriction factors enhances HIV-1 infection.

J Cell Sci 2015 Apr 25;128(8):1607-16. Epub 2015 Feb 25.

Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel

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http://dx.doi.org/10.1242/jcs.167817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406127PMC
April 2015

Crowdfunding effort identifies the causative mutation in a patient with nystagmus, microcephaly, dystonia and hypomyelination.

J Genet Genomics 2015 Feb 10;42(2):79-81. Epub 2015 Jan 10.

Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.jgg.2014.12.004DOI Listing
February 2015

Emergence and transmission of arbovirus evolutionary intermediates with epidemic potential.

Cell Host Microbe 2014 Jun;15(6):706-16

Viral Populations and Pathogenesis Unit, Institut Pasteur, Centre National de la Recherche Scientifique UMR 3569, 28 rue du Dr Roux, 75724 Paris Cedex 15, France. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2014.05.008DOI Listing
June 2014

Next-generation sequencing of small RNAs from inner ear sensory epithelium identifies microRNAs and defines regulatory pathways.

BMC Genomics 2014 Jun 18;15:484. Epub 2014 Jun 18.

Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1186/1471-2164-15-484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073505PMC
June 2014

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

Authors:
Catherine A Brownstein Alan H Beggs Nils Homer Barry Merriman Timothy W Yu Katherine C Flannery Elizabeth T DeChene Meghan C Towne Sarah K Savage Emily N Price Ingrid A Holm Lovelace J Luquette Elaine Lyon Joseph Majzoub Peter Neupert David McCallie Peter Szolovits Huntington F Willard Nancy J Mendelsohn Renee Temme Richard S Finkel Sabrina W Yum Livija Medne Shamil R Sunyaev Ivan Adzhubey Christopher A Cassa Paul I W de Bakker Hatice Duzkale Piotr Dworzyński William Fairbrother Laurent Francioli Birgit H Funke Monica A Giovanni Robert E Handsaker Kasper Lage Matthew S Lebo Monkol Lek Ignaty Leshchiner Daniel G MacArthur Heather M McLaughlin Michael F Murray Tune H Pers Paz P Polak Soumya Raychaudhuri Heidi L Rehm Rachel Soemedi Nathan O Stitziel Sara Vestecka Jochen Supper Claudia Gugenmus Bernward Klocke Alexander Hahn Max Schubach Mortiz Menzel Saskia Biskup Peter Freisinger Mario Deng Martin Braun Sven Perner Richard J H Smith Janeen L Andorf Jian Huang Kelli Ryckman Val C Sheffield Edwin M Stone Thomas Bair E Ann Black-Ziegelbein Terry A Braun Benjamin Darbro Adam P DeLuca Diana L Kolbe Todd E Scheetz Aiden E Shearer Rama Sompallae Kai Wang Alexander G Bassuk Erik Edens Katherine Mathews Steven A Moore Oleg A Shchelochkov Pamela Trapane Aaron Bossler Colleen A Campbell Jonathan W Heusel Anne Kwitek Tara Maga Karin Panzer Thomas Wassink Douglas Van Daele Hela Azaiez Kevin Booth Nic Meyer Michael M Segal Marc S Williams Gerard Tromp Peter White Donald Corsmeier Sara Fitzgerald-Butt Gail Herman Devon Lamb-Thrush Kim L McBride David Newsom Christopher R Pierson Alexander T Rakowsky Aleš Maver Luca Lovrečić Anja Palandačić Borut Peterlin Ali Torkamani Anna Wedell Mikael Huss Andrey Alexeyenko Jessica M Lindvall Måns Magnusson Daniel Nilsson Henrik Stranneheim Fulya Taylan Christian Gilissen Alexander Hoischen Bregje van Bon Helger Yntema Marcel Nelen Weidong Zhang Jason Sager Lu Zhang Kathryn Blair Deniz Kural Michael Cariaso Greg G Lennon Asif Javed Saloni Agrawal Pauline C Ng Komal S Sandhu Shuba Krishna Vamsi Veeramachaneni Ofer Isakov Eran Halperin Eitan Friedman Noam Shomron Gustavo Glusman Jared C Roach Juan Caballero Hannah C Cox Denise Mauldin Seth A Ament Lee Rowen Daniel R Richards F Anthony San Lucas Manuel L Gonzalez-Garay C Thomas Caskey Yu Bai Ying Huang Fang Fang Yan Zhang Zhengyuan Wang Jorge Barrera Juan M Garcia-Lobo Domingo González-Lamuño Javier Llorca Maria C Rodriguez Ignacio Varela Martin G Reese Francisco M De La Vega Edward Kiruluta Michele Cargill Reece K Hart Jon M Sorenson Gholson J Lyon David A Stevenson Bruce E Bray Barry M Moore Karen Eilbeck Mark Yandell Hongyu Zhao Lin Hou Xiaowei Chen Xiting Yan Mengjie Chen Cong Li Can Yang Murat Gunel Peining Li Yong Kong Austin C Alexander Zayed I Albertyn Kym M Boycott Dennis E Bulman Paul M K Gordon A Micheil Innes Bartha M Knoppers Jacek Majewski Christian R Marshall Jillian S Parboosingh Sarah L Sawyer Mark E Samuels Jeremy Schwartzentruber Isaac S Kohane David M Margulies

Genome Biol 2014 Mar 25;15(3):R53. Epub 2014 Mar 25.

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http://dx.doi.org/10.1186/gb-2014-15-3-r53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073084PMC
March 2014

Exome sequencing analysis: a guide to disease variant detection.

Methods Mol Biol 2013 ;1038:137-58

Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1007/978-1-62703-514-9_8DOI Listing
February 2014

MicroRNA editing facilitates immune elimination of HCMV infected cells.

PLoS Pathog 2014 Feb 27;10(2):e1003963. Epub 2014 Feb 27.

The Lautenberg Center for General and Tumor Immunology, The BioMedical Research Institute Israel Canada of the Faculty of Medicine, The Hebrew University Hadassah Medical School, Jerusalem, Israel.

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http://dx.doi.org/10.1371/journal.ppat.1003963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937316PMC
February 2014

Cole Disease Results from Mutations in ENPP1.

Am J Hum Genet 2013 Oct 26;93(4):752-7. Epub 2013 Sep 26.

Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv 642395, Israel; Department of Human Molecular Genetics & Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel.

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http://dx.doi.org/10.1016/j.ajhg.2013.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791268PMC
October 2013

Missense mutation in the MEN1 gene discovered through whole exome sequencing co-segregates with familial hyperparathyroidism.

Genet Res (Camb) 2013 Aug;95(4):114-20

Department of Cell and Developmental Biology, The Sackler School of Medicine, Tel Aviv University, Tel-Aviv, Israel.

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https://www.cambridge.org/core/services/aop-cambridge-core/c
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http://dx.doi.org/10.1017/S0016672313000141DOI Listing
August 2013

Analysis of insertion-deletion from deep-sequencing data: software evaluation for optimal detection.

Brief Bioinform 2013 Jan 24;14(1):46-55. Epub 2012 Mar 24.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1093/bib/bbs013DOI Listing
January 2013

Vaccinia virus infection suppresses the cell microRNA machinery.

Arch Virol 2012 Sep 7;157(9):1719-27. Epub 2012 Jun 7.

Department of Virology and Molecular Genetics, Faculty of Health Sciences, Ben Gurion University of the Negev, 84105 Beer Sheva, Israel.

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http://dx.doi.org/10.1007/s00705-012-1366-zDOI Listing
September 2012

The microRNA Transcriptome of Human Cytomegalovirus (HCMV).

Open Virol J 2012 11;6:38-48. Epub 2012 Apr 11.

Department of Virology and Molecular Genetics, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 84105, Israel.

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http://dx.doi.org/10.2174/1874357901206010038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377890PMC
August 2012

Novel insight into the non-coding repertoire through deep sequencing analysis.

Nucleic Acids Res 2012 Jun 9;40(11):e86. Epub 2012 Mar 9.

Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1093/nar/gks228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367215PMC
June 2012

miRviewer: a multispecies microRNA homologous viewer.

BMC Res Notes 2012 Feb 13;5:92. Epub 2012 Feb 13.

Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1186/1756-0500-5-92DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292992PMC
February 2012

Pathogen detection using short-RNA deep sequencing subtraction and assembly.

Bioinformatics 2011 Aug 11;27(15):2027-30. Epub 2011 Jun 11.

Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1093/bioinformatics/btr349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137223PMC
August 2011