Oded Kleifeld

Oded Kleifeld

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Oded Kleifeld

Oded Kleifeld

Publications by authors named "Oded Kleifeld"

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Remodeling Membrane Binding by Mono-Ubiquitylation.

Biomolecules 2019 07 31;9(8). Epub 2019 Jul 31.

School of Neurobiology, Biochemistry and Biophysics, The George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.3390/biom9080325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723200PMC
July 2019

Integration of Two In-depth Quantitative Proteomics Approaches Determines the Kallikrein-related Peptidase 7 (KLK7) Degradome in Ovarian Cancer Cell Secretome.

Mol Cell Proteomics 2019 05 31;18(5):818-836. Epub 2019 Jan 31.

From the ‡Queensland University of Technology (QUT), Institute of Health and Biomedical Innovation (IHBI) and School of Biomedical Sciences at the Translational Research Institute, 37 Kent Street, Woolloongabba, Queensland, 4102, Australia;

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http://dx.doi.org/10.1074/mcp.RA118.001304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495248PMC
May 2019

Preassembled GPCR signaling complexes mediate distinct cellular responses to ultralow ligand concentrations.

Sci Signal 2018 10 9;11(551). Epub 2018 Oct 9.

Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1126/scisignal.aan1188DOI Listing
October 2018

Identification of Novel Acinetobacter baumannii Type VI Secretion System Antibacterial Effector and Immunity Pairs.

Infect Immun 2018 08 23;86(8). Epub 2018 Jul 23.

Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Australia

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http://dx.doi.org/10.1128/IAI.00297-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056853PMC
August 2018

Biodosimetric transcriptional and proteomic changes are conserved in irradiated human tissue.

Radiat Environ Biophys 2018 Aug 30;57(3):241-249. Epub 2018 May 30.

Tumor Suppression Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1007/s00411-018-0746-5DOI Listing
August 2018

Cleavage of the leptin receptor by matrix metalloproteinase-2 promotes leptin resistance and obesity in mice.

Sci Transl Med 2018 08;10(455)

Department of Bioengineering, Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1126/scitranslmed.aah6324DOI Listing
August 2018

Exploring the oncoproteomic response of human prostate cancer to therapeutic radiation using data-independent acquisition (DIA) mass spectrometry.

Prostate 2018 06 9;78(8):563-575. Epub 2018 Mar 9.

Division of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1002/pros.23500DOI Listing
June 2018

Activity-Based Probes Developed by Applying a Sequential Dehydroalanine Formation Strategy to Expressed Proteins Reveal a Potential α-Globin-Modulating Deubiquitinase.

Angew Chem Int Ed Engl 2018 05 14;57(20):5645-5649. Epub 2018 Apr 14.

Schulich Faculty of Chemistry, Technion Israel Institute of Technology, Haifa, 3200008, Israel.

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http://doi.wiley.com/10.1002/anie.201800032
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http://dx.doi.org/10.1002/anie.201800032DOI Listing
May 2018

Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis.

PLoS Pathog 2018 03 30;14(3):e1006945. Epub 2018 Mar 30.

Biomedicine Discovery Institute and Department of Biochemistry & Molecular Biology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1371/journal.ppat.1006945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877877PMC
March 2018

Studying Protein Ubiquitylation in Yeast.

Methods Mol Biol 2016 ;1449:117-42

Institut Jacques Monod, UMR 7592 CNRS/Univ. Paris Diderot, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1007/978-1-4939-3756-1_5DOI Listing
January 2018

Structure-function analyses of a pertussis-like toxin from pathogenic reveal a distinct mechanism of inhibition of trimeric G-proteins.

J Biol Chem 2017 09 29;292(36):15143-15158. Epub 2017 Jun 29.

the Department of Animal, Plant and Soil Science and Centre for AgriBioscience, La Trobe University, Bundoora, Victoria 3086, Australia

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http://dx.doi.org/10.1074/jbc.M117.796094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592689PMC
September 2017

Clinical and Pharmacological Investigation of Myotoxicity in Sri Lankan Russell's Viper (Daboia russelii) Envenoming.

PLoS Negl Trop Dis 2016 12 2;10(12):e0005172. Epub 2016 Dec 2.

Monash Venom Group, Department of Pharmacology, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1371/journal.pntd.0005172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135039PMC
December 2016

Synthetic Uncleavable Ubiquitinated Proteins Dissect Proteasome Deubiquitination and Degradation, and Highlight Distinctive Fate of Tetraubiquitin.

J Am Chem Soc 2016 12 6;138(49):16004-16015. Epub 2016 Dec 6.

Schulich Faculty of Chemistry, Technion-Israel Institute of Technology , 3200008 Haifa, Israel.

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http://dx.doi.org/10.1021/jacs.6b09611DOI Listing
December 2016

Physicochemical properties that control protein aggregation also determine whether a protein is retained or released from necrotic cells.

Open Biol 2016 11;6(11)

Australian Centre for Blood Diseases, Alfred Medical Research and Education Precinct (AMREP), Monash University, Melbourne, Victoria 3004, Australia.

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http://dx.doi.org/10.1098/rsob.160098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133435PMC
November 2016

Structure of ubiquitylated-Rpn10 provides insight into its autoregulation mechanism.

Nat Commun 2016 10 4;7:12960. Epub 2016 Oct 4.

Department of Biochemistry and Molecular Biology and the Institute of Structural Biology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1038/ncomms12960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059453PMC
October 2016

Changes in protein abundance are observed in bacterial isolates from a natural host.

Front Cell Infect Microbiol 2015 14;5:71. Epub 2015 Oct 14.

Monash Biomedical Proteomics Facility, Department of Biochemistry and Molecular Biology, Monash University Clayton, VIC, Australia.

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http://dx.doi.org/10.3389/fcimb.2015.00071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604328PMC
June 2016

The RNA-Binding Chaperone Hfq Is an Important Global Regulator of Gene Expression in Pasteurella multocida and Plays a Crucial Role in Production of a Number of Virulence Factors, Including Hyaluronic Acid Capsule.

Infect Immun 2016 05 22;84(5):1361-1370. Epub 2016 Apr 22.

Department of Microbiology, Infection and Immunity Program, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia

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http://dx.doi.org/10.1128/IAI.00122-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862696PMC
May 2016

Conformational changes during pore formation by the perforin-related protein pleurotolysin.

PLoS Biol 2015 Feb 5;13(2):e1002049. Epub 2015 Feb 5.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, Australia; The ARC Centre of Excellence in Advanced Molecular Imaging, Monash University, Melbourne, Australia; Department of Microbiology, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1371/journal.pbio.1002049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318580PMC
February 2015

Proteomic characterization of a natural host-pathogen interaction: repertoire of in vivo expressed bacterial and host surface-associated proteins.

J Proteome Res 2015 Jan 30;14(1):120-32. Epub 2014 Oct 30.

Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, ‡Department of Microbiology, §Department of Biochemistry and Molecular Biology, Monash University , Clayton, Victoria 3800, Australia.

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http://pubs.acs.org/doi/10.1021/pr5010086
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http://dx.doi.org/10.1021/pr5010086DOI Listing
January 2015

LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification.

Nat Methods 2015 Jan 24;12(1):55-8. Epub 2014 Nov 24.

1] Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada. [2] Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada. [3] Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/nmeth.3177DOI Listing
January 2015

Granzyme B promotes cytotoxic lymphocyte transmigration via basement membrane remodeling.

Immunity 2014 Dec 28;41(6):960-72. Epub 2014 Nov 28.

Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.11.012DOI Listing
December 2014

Oxidation of an exposed methionine instigates the aggregation of glyceraldehyde-3-phosphate dehydrogenase.

J Biol Chem 2014 Sep 1;289(39):26922-36. Epub 2014 Aug 1.

From the Australian Centre for Blood Diseases, Monash University, Melbourne 3004, Victoria, Australia and

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http://dx.doi.org/10.1074/jbc.M114.570275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175333PMC
September 2014

Structural and mechanistic insight into alkane hydroxylation by Pseudomonas putida AlkB.

Biochem J 2014 Jun;460(2):283-93

§School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1042/BJ20131648DOI Listing
June 2014

Reversible 26S proteasome disassembly upon mitochondrial stress.

Cell Rep 2014 Jun 22;7(5):1371-1380. Epub 2014 May 22.

Department of Biology, Technion-Israel Institute of Technology, Haifa 32000, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.04.030DOI Listing
June 2014

Recognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome system.

Mol Cell Proteomics 2012 Dec 26;11(12):1595-611. Epub 2012 Oct 26.

Department of Chemistry and Biochemistry, Center for Biomolecular Structure and Organization, University of Maryland, College Park, MD 20742, USA.

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http://dx.doi.org/10.1074/mcp.M112.022467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518131PMC
December 2012

Synthetic biology approach to reconstituting the ubiquitylation cascade in bacteria.

EMBO J 2012 Jan 11;31(2):378-90. Epub 2011 Nov 11.

Department of Biochemistry and Molecular Biology, The Institute for Structural Biology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1038/emboj.2011.397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261559PMC
January 2012

Identification of proteolytic products and natural protein N-termini by Terminal Amine Isotopic Labeling of Substrates (TAILS).

Methods Mol Biol 2011 ;753:273-87

Department of Pathology and Laboratory Medecine, Centre for Blood Research, University of British Columbia, Vancouver, BC, Canada.

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http://link.springer.com/content/pdf/10.1007/978-1-61779-148
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http://link.springer.com/10.1007/978-1-61779-148-2_18
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http://dx.doi.org/10.1007/978-1-61779-148-2_18DOI Listing
September 2011

Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates.

Nat Protoc 2011 Sep 22;6(10):1578-611. Epub 2011 Sep 22.

Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/nprot.2011.382DOI Listing
September 2011

Nuclear import of an intact preassembled proteasome particle.

Mol Biol Cell 2011 Mar 2;22(6):880-91. Epub 2011 Feb 2.

Department of Biology, Technion-Israel Institute of Technology, Haifa 32000, Israel.

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http://dx.doi.org/10.1091/mbc.E10-07-0595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057711PMC
March 2011

Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products.

Nat Biotechnol 2010 Mar 7;28(3):281-8. Epub 2010 Mar 7.

Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/nbt.1611DOI Listing
March 2010

Nonconformity in ubiquitin compliance.

EMBO J 2009 Jul;28(13):1825-7

Department of Biology, Technion-Israel Institute of Technology, Haifa, Israel.

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http://dx.doi.org/10.1038/emboj.2009.132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711179PMC
July 2009

Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy.

Nat Rev Cancer 2006 03;6(3):227-39

University of British Columbia Centre for Blood Research, CBCRA Program in Breast Cancer Metastasis, Department of Oral Biological & Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z3.

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http://dx.doi.org/10.1038/nrc1821DOI Listing
March 2006

Structural basis for potent slow binding inhibition of human matrix metalloproteinase-2 (MMP-2).

J Biol Chem 2003 Jul 4;278(29):27009-15. Epub 2003 Apr 4.

Department of Structural Biology, The Weizmann Institute of Science, Rehovot, 76100, Israel.

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http://www.jbc.org/content/278/29/27009.full.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M301139200
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http://dx.doi.org/10.1074/jbc.M301139200DOI Listing
July 2003

The conserved Glu-60 residue in Thermoanaerobacter brockii alcohol dehydrogenase is not essential for catalysis.

Protein Sci 2003 Mar;12(3):468-79

Department of Structural Biology, The Weizmann Institute of Science, Rehovot 76100, Israel.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2312447PMC
http://dx.doi.org/10.1110/ps.0221603DOI Listing
March 2003

Active site electronic structure and dynamics during metalloenzyme catalysis.

Nat Struct Biol 2003 Feb;10(2):98-103

Department of Structural Biology, The Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1038/nsb889DOI Listing
February 2003