Publications by authors named "Nuria Morral"

20Publications

Impact of silencing hepatic SREBP-1 on insulin signaling.

PLoS One 2018 3;13(5):e0196704. Epub 2018 May 3.

Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196704PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933792PMC
August 2018

Gene therapy for inherited retinal and optic nerve degenerations.

Expert Opin Biol Ther 2018 01 23;18(1):37-49. Epub 2017 Oct 23.

a Department of Ophthalmology , Indiana University School of Medicine , Indianapolis , IN , USA.

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http://dx.doi.org/10.1080/14712598.2018.1389886DOI Listing
January 2018

Gene therapy for age-related macular degeneration.

Expert Opin Biol Ther 2017 10 20;17(10):1235-1244. Epub 2017 Jul 20.

a Department of Ophthalmology , Indiana University School of Medicine , Indianapolis , IN , USA.

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http://dx.doi.org/10.1080/14712598.2017.1356817DOI Listing
October 2017

Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice.

J Biol Chem 2017 06 8;292(25):10455-10464. Epub 2017 May 8.

From the Departments of Biochemistry and Molecular Biology and

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http://dx.doi.org/10.1074/jbc.M117.786525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481557PMC
June 2017

Gene targets of mouse miR-709: regulation of distinct pools.

Sci Rep 2016 Jan 8;6:18958. Epub 2016 Jan 8.

Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.

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http://www.nature.com/articles/srep18958
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http://dx.doi.org/10.1038/srep18958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705522PMC
January 2016

Enhancing hepatic mitochondrial fatty acid oxidation stimulates eating in food-deprived mice.

Am J Physiol Regul Integr Comp Physiol 2015 Jan 26;308(2):R131-7. Epub 2014 Nov 26.

Department of Medical and Molecular Genetics, and Center for Diabetes Research, Indiana University School of Medicine, Indianapolis, Indiana

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http://dx.doi.org/10.1152/ajpregu.00279.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297862PMC
January 2015

Vector and helper genome rearrangements occur during production of helper-dependent adenoviral vectors.

Hum Gene Ther Methods 2013 Feb;24(1):1-10

Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://www.liebertpub.com/doi/10.1089/hgtb.2012.198
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http://dx.doi.org/10.1089/hgtb.2012.198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015077PMC
February 2013

shRNA-induced interferon-stimulated gene analysis.

Methods Mol Biol 2012 ;820:163-77

Department of Medical and Molecular Genetics, and Center for Diabetes Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1007/978-1-61779-439-1_10DOI Listing
March 2012

Constitutive expression of short hairpin RNA in vivo triggers buildup of mature hairpin molecules.

Hum Gene Ther 2011 Dec 4;22(12):1483-97. Epub 2011 Oct 4.

Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1089/hum.2010.234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237692PMC
December 2011

Comparative nucleic acid transfection efficacy in primary hepatocytes for gene silencing and functional studies.

BMC Res Notes 2011 Jan 18;4. Epub 2011 Jan 18.

Department of Medical and Molecular Genetics, Indiana University School of Medicine, 975 West Walnut St, IB130, Indianapolis, Indiana 46202, USA.

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http://dx.doi.org/10.1186/1756-0500-4-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033823PMC
January 2011

Accurate single-day titration of adenovirus vectors based on equivalence of protein VII nuclear dots and infectious particles.

J Virol Methods 2009 Aug 3;159(2):251-8. Epub 2009 May 3.

Department of Microbiology, University of Virginia Health System, P.O. Box 800734, Charlottesville, VA 22908-0734, USA.

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http://dx.doi.org/10.1016/j.jviromet.2009.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774845PMC
August 2009

Robust hepatic gene silencing for functional studies using helper-dependent adenoviral vectors.

Hum Gene Ther 2009 Jan;20(1):87-94

Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1089/hum.2008.081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855247PMC
January 2009

Helper-dependent adenovirus-mediated short hairpin RNA expression in the liver activates the interferon response.

J Biol Chem 2008 Jan 19;283(4):2120-8. Epub 2007 Nov 19.

Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

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http://www.jbc.org/content/283/4/2120.full.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M704178200
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http://dx.doi.org/10.1074/jbc.M704178200DOI Listing
January 2008

Transcription releases protein VII from adenovirus chromatin.

Virology 2007 Dec 20;369(2):411-22. Epub 2007 Sep 20.

Department of Microbiology, University of Virginia Health System, PO Box 800734, Charlottesville, VA 22908-0734, USA.

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http://dx.doi.org/10.1016/j.virol.2007.08.012DOI Listing
December 2007

Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the liver.

J Lipid Res 2007 Jul 21;48(7):1499-510. Epub 2007 Apr 21.

Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1194/jlr.M700090-JLR200DOI Listing
July 2007

Novel targets and therapeutic strategies for type 2 diabetes.

Authors:
Núria Morral

Trends Endocrinol Metab 2003 May-Jun;14(4):169-75

Carl C. Icahn Center for Gene Therapy and Molecular Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/s1043-2760(03)00031-6DOI Listing
January 2004

Adenovirus-mediated expression of glucokinase in the liver as an adjuvant treatment for type 1 diabetes.

Hum Gene Ther 2002 Sep;13(13):1561-70

Carl C. Icahn Institute for Gene Therapy and Molecular Medicine, Mount Sinai School of Medicine, New York, NY 10029-6574, USA.

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http://dx.doi.org/10.1089/10430340260201653DOI Listing
September 2002

Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons.

Hum Gene Ther 2002 Jan;13(1):143-54

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1089/10430340152712692DOI Listing
January 2002

Basal insulin gene expression significantly improves conventional insulin therapy in type 1 diabetic rats.

Diabetes 2002 Jan;51(1):130-8

Carl C. Icahn Institute for Gene Therapy and Molecular Medicine, Mount Sinai School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.2337/diabetes.51.1.130DOI Listing
January 2002