Nunilo Cremades

Nunilo Cremades

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Nunilo Cremades

Nunilo Cremades

Publications by authors named "Nunilo Cremades"

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Preparation of α-Synuclein Amyloid Assemblies for Toxicity Experiments.

Methods Mol Biol 2018 ;1779:45-60

Institute for Biocomputation and Physics of Complex Systems (BIFI)-Joint Unit BIFI-IQFR (CSIC), University of Zaragoza, Zaragoza 50018, Spain.

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http://dx.doi.org/10.1007/978-1-4939-7816-8_4DOI Listing
July 2019

Defining α-synuclein species responsible for Parkinson's disease phenotypes in mice.

J Biol Chem 2019 Jul 29;294(27):10392-10406. Epub 2019 May 29.

From the Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, Alabama 35294,

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http://dx.doi.org/10.1074/jbc.RA119.007743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615698PMC
July 2019

The contribution of biophysical and structural studies of protein self-assembly to the design of therapeutic strategies for amyloid diseases.

Neurobiol Dis 2018 Jan 12;109(Pt B):178-190. Epub 2017 Jul 12.

Department of Chemistry, Centre for Misfolding Diseases, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S09699961173016
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http://dx.doi.org/10.1016/j.nbd.2017.07.009DOI Listing
January 2018

Inhibition of α-Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α-Synuclein Species.

Biochemistry 2017 03 23;56(9):1177-1180. Epub 2017 Feb 23.

Biocomputation and Complex Systems Physics Institute (BIFI)-Joint Unit BIFI-IQFR (CSIC), University of Zaragoza , 50018 Zaragoza, Spain.

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http://dx.doi.org/10.1021/acs.biochem.6b01178DOI Listing
March 2017

Cell surface localised Hsp70 is a cancer specific regulator of clathrin-independent endocytosis.

FEBS Lett 2015 Sep 6;589(19 Pt B):2747-53. Epub 2015 Aug 6.

Center for Advanced Bioanalysis GmbH, Linz, Austria; Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2015.07.037DOI Listing
September 2015

Insights in the (un)structural organization of Bacillus pasteurii UreG, an intrinsically disordered GTPase enzyme.

Mol Biosyst 2012 Jan 16;8(1):220-8. Epub 2011 Sep 16.

Laboratory of Bioinorganic Chemistry, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1039/c1mb05227fDOI Listing
January 2012

Discovery of specific flavodoxin inhibitors as potential therapeutic agents against Helicobacter pylori infection.

ACS Chem Biol 2009 Nov;4(11):928-38

Departamento de Bioquimica y Biologia Molecular y Celular, Facultad de Ciencias, Universidad de Zaragoza, Spain.

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http://dx.doi.org/10.1021/cb900166qDOI Listing
November 2009

Conformational stability of Helicobacter pylori flavodoxin: fit to function at pH 5.

J Biol Chem 2008 Feb 11;283(5):2883-95. Epub 2007 Nov 11.

Biocomputation and Complex Systems Physics Institute, Departamento de Bioquímica y Biología Molecular y Celular, Facultad de Ciencias, Universidad de Zaragosa, Zaragosa, Spain.

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http://dx.doi.org/10.1074/jbc.M705677200DOI Listing
February 2008

The flavodoxin from Helicobacter pylori: structural determinants of thermostability and FMN cofactor binding.

Biochemistry 2008 Jan 21;47(2):627-39. Epub 2007 Dec 21.

Biocomputation and Complex Systems Physics Institute, Universidad de Zaragoza, 50009-Zaragoza, Spain.

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http://dx.doi.org/10.1021/bi701365eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2531135PMC
January 2008

Common conformational changes in flavodoxins induced by FMN and anion binding: the structure of Helicobacter pylori apoflavodoxin.

Proteins 2007 Nov;69(3):581-94

Biocomputation and Complex Systems Physics Institute (BiFi), Universidad de Zaragoza, Unidad Asociada al IQFR-CSIC, Zaragoza, Spain.

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http://doi.wiley.com/10.1002/prot.21410
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http://dx.doi.org/10.1002/prot.21410DOI Listing
November 2007

Antiparasitic drug nitazoxanide inhibits the pyruvate oxidoreductases of Helicobacter pylori, selected anaerobic bacteria and parasites, and Campylobacter jejuni.

Antimicrob Agents Chemother 2007 Mar 11;51(3):868-76. Epub 2006 Dec 11.

Division of Infectious Diseases and International Health, 409 Lane Road, University of Virginia Health Systems, Charlottesville, VA 22908-1340, USA.

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http://aac.asm.org/cgi/doi/10.1128/AAC.01159-06
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http://dx.doi.org/10.1128/AAC.01159-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1803158PMC
March 2007

The native-state ensemble of proteins provides clues for folding, misfolding and function.

Trends Biochem Sci 2006 Sep 25;31(9):494-6. Epub 2006 Jul 25.

Department of Biochemistry and BIFI, University of Zaragoza, Zaragoza 50009, Spain.

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http://dx.doi.org/10.1016/j.tibs.2006.07.001DOI Listing
September 2006

Filling small, empty protein cavities: structural and energetic consequences.

J Mol Biol 2006 May 10;358(3):701-12. Epub 2006 Mar 10.

Departamento de Bioquímica y Biología Molecular y Celular, Facultad de Ciencias, Universidad de Zaragoza, 50009 Zaragoza, Spain.

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http://dx.doi.org/10.1016/j.jmb.2006.02.060DOI Listing
May 2006

Towards a new therapeutic target: Helicobacter pylori flavodoxin.

Biophys Chem 2005 Apr 7;115(2-3):267-76. Epub 2005 Jan 7.

Biocomputation and Complex Systems Physics Institute, Spain.

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http://dx.doi.org/10.1016/j.bpc.2004.12.045DOI Listing
April 2005