Publications by authors named "Nordin Haji Lajis"

16Publications

SRJ09, a promising anticancer drug lead: Elucidation of mechanisms of antiproliferative and apoptogenic effects and assessment of in vivo antitumor efficacy.

Pharmacol Res 2016 05 3;107:66-78. Epub 2016 Mar 3.

Pharmacotherapeutics Unit, Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia; Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor, Malaysia. Electronic address:

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May 2016

SRJ23, a new semisynthetic andrographolide derivative: in vitro growth inhibition and mechanisms of cell cycle arrest and apoptosis in prostate cancer cells.

Cell Biol Toxicol 2014 Oct 29;30(5):269-88. Epub 2014 Jul 29.

Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.

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October 2014

In vitro 3D colon tumor penetrability of SRJ09, a new anti-cancer andrographolide analog.

Invest New Drugs 2014 Oct 31;32(5):806-14. Epub 2014 May 31.

Pharmacotherapeutics Unit, Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.

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October 2014

Synthesis and effects of pyrazolines and isoxazoles on the phagocytic chemotaxis and release of reactive oxygen species by zymosan stimulated human neutrophils.

Med Chem 2013 Dec;9(8):1091-8

Drug and Herbal Research Center, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia.

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December 2013

BDMC33, A curcumin derivative suppresses inflammatory responses in macrophage-like cellular system: role of inhibition in NF-κB and MAPK signaling pathways.

Int J Mol Sci 2012 6;13(3):2985-3008. Epub 2012 Mar 6.

Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia; E-Mail:

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September 2015

Effects of diarylpentanoid analogues of curcumin on chemiluminescence and chemotactic activities of phagocytes.

J Pharm Pharmacol 2012 Mar 16;64(3):404-12. Epub 2011 Dec 16.

Drug and Herbal Research Center, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

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March 2012

Cardamonin from Alpinia rafflesiana inhibits inflammatory responses in IFN-γ/LPS-stimulated BV2 microglia via NF-κB signalling pathway.

Int Immunopharmacol 2012 Apr 3;12(4):657-65. Epub 2012 Feb 3.

Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor DE, Malaysia.

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April 2012

A curcumin derivative, 2,6-bis(2,5-dimethoxybenzylidene)-cyclohexanone (BDMC33) attenuates prostaglandin E2 synthesis via selective suppression of cyclooxygenase-2 in IFN-γ/LPS-stimulated macrophages.

Molecules 2011 Nov 23;16(11):9728-38. Epub 2011 Nov 23.

Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.

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November 2011

Derivatives of pheophorbide-a and pheophorbide-b from photocytotoxic Piper penangense extract.

Chem Biodivers 2011 Mar;8(3):494-502

Cancer Research Initiatives Foundation, Sime Darby Medical Center, 47500 Subang Jaya, Selangor Darul Ehsan, Malaysia.

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March 2011

Docking and 3D-QSAR modeling of cyclin-dependent kinase 5/p25 inhibitors.

J Mol Model 2011 May 5;17(5):1149-61. Epub 2010 Aug 5.

Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.

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May 2011

Chemopreventive properties of phytosterols and maslinic acid extracted from Coleus tuberosus in inhibiting the expression of EBV early-antigen in Raji cells.

Chem Biodivers 2010 May;7(5):1267-75

Department of Science, Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Jalan Genting Kelang, Setapak, 53300 Kuala Lumpur, Malaysia.

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May 2010

Naturally occurring labdane diterpene and benzofuran from Globba pendula.

Nat Prod Commun 2009 Aug;4(8):1031-6

Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.

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August 2009

Synthesis and biological evaluation of curcumin-like diarylpentanoid analogues for anti-inflammatory, antioxidant and anti-tyrosinase activities.

Eur J Med Chem 2009 Aug 26;44(8):3195-200. Epub 2009 Mar 26.

Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, UPM Serdang, Selangor, Malaysia.

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August 2009

Semisynthesis and in vitro anticancer activities of andrographolide analogues.

Phytochemistry 2007 Mar 17;68(6):904-12. Epub 2007 Jan 17.

Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.

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March 2007

Semisynthesis and cytotoxic activities of andrographolide analogues.

J Enzyme Inhib Med Chem 2006 Apr;21(2):145-55

Clinical Pharmacology Laboratory, Division of Medical Sciences, National Cancer Centre, 11 Hospital Drive, 169610, Singapore.

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April 2006