Norbert Vey

Norbert Vey

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Norbert Vey

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Myelodysplastic Syndromes: How to Recognize Risk and Avoid Acute Myeloid Leukemia Transformation.

Curr Oncol Rep 2020 Jan 23;22(1). Epub 2020 Jan 23.

Aix-Marseille Univ, Inserm, CNRS, CRCM, Institut Paoli-Calmettes, 232 Bvd Sainte Marguerite, 13009, Marseille, France.

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http://dx.doi.org/10.1007/s11912-020-0869-0DOI Listing
January 2020

How should we diagnose and treat blastic plasmacytoid dendritic cell neoplasm patients?

Authors:
Francine Garnache-Ottou Chrystelle Vidal Sabeha Biichlé Florian Renosi Eve Poret Maïder Pagadoy Maxime Desmarets Anne Roggy Estelle Seilles Lou Soret Françoise Schillinger Sandrine Puyraimond Tony Petrella Claude Preudhomme Christophe Roumier Elisabeth A MacIntyre Véronique Harrivel Yohan Desbrosses Bérengère Gruson Franck Geneviève Sylvain Thepot Yuriy Drebit Thibaut Leguay François-Xavier Gros Nicolas Lechevalier Pascale Saussoy Véronique Salaun Edouard Cornet Zehaira Benseddik Richard Veyrat-Masson Orianne Wagner-Ballon Célia Salanoubat Marc Maynadié Julien Guy Denis Caillot Marie-Christine Jacob Jean-Yves Cahn Rémy Gressin Johann Rose Bruno Quesnel Estelle Guerin Franck Trimoreau Jean Feuillard Marie-Pierre Gourin Adriana Plesa Lucile Baseggio Isabelle Arnoux Norbert Vey Didier Blaise Romaric Lacroix Christine Arnoulet Blandine Benet Véronique Dorvaux Caroline Bret Bernard Drenou Agathe Debliquis Véronique Latger-Cannard Caroline Bonmati Marie-Christine Bene Pierre Peterlin Michel Ticchioni Pierre-Simon Rohrlich Anne Arnaud Stefan Wickenhauser Valérie Bardet Sabine Brechignac Benjamin Papoular Victoria Raggueneau Jacques Vargaftig Rémi Letestu Daniel Lusina Thorsten Braun Vincent Foissaud Jérôme Tamburini Hind Bennani Nicolas Freynet Catherine Cordonnier Magali Le Garff-Tavernier Nathalie Jacques Karim Maloum Damien Roos-Weil Didier Bouscary Vahid Asnafi Ludovic Lhermitte Felipe Suarez Etienne Lengline Frédéric Féger Giorgia Battipaglia Mohamad Mohty Sabrina Bouyer Ouda Ghoual Elodie Dindinaud Caroline Basle Mathieu Puyade Carinne Lafon Thierry Fest Mikael Roussel Xavier Cahu Elsa Bera Sylvie Daliphard Fabrice Jardin Lydia Campos Françoise Solly Denis Guyotat Anne-Cécile Galoisy Alice Eischen Caroline Mayeur-Rousse Blandine Guffroy Christian Recher Marie Loosveld Alice Garnier Vincent Barlogis Maria Alessandra Rosenthal Sophie Brun Nathalie Contentin Sébastien Maury Mary Callanan Christine Lefebvre Natacha Maillard Patricia Okamba Christophe Ferrand Olivier Adotevi Philippe Saas Fanny Angelot-Delettre Delphine Binda Eric Deconinck

Blood Adv 2019 Dec;3(24):4238-4251

University of Bourgogne Franche-Comté, INSERM, Établissement Français du Sang Bourgogne/Franche-Comté, Unite Mixte de Recherche (UMR) 1098, RIGHT (Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique), Besançon, France.

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http://dx.doi.org/10.1182/bloodadvances.2019000647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929390PMC
December 2019

Alternative Effective and Safe Induction Regimens for Newly Diagnosed Acute Myeloid Leukemia in Patients With Cardiac Contraindication to Anthracyclines.

Clin Lymphoma Myeloma Leuk 2019 Nov 26. Epub 2019 Nov 26.

CHU of Nice, Hematology Department, Cote D'Azur University, Nice Sophia Antipolis University, Nice, France; INSERM U1065, Mediterranean Center of Molecular Medecine, Cote D'Azur University, Nice, France. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2019.11.016DOI Listing
November 2019

Risk of Hematologic Malignant Neoplasms after Postoperative Treatment of Breast Cancer.

Cancers (Basel) 2019 Sep 29;11(10). Epub 2019 Sep 29.

EPI-PHARE (French National Agency for Medicines and Health Products Safety (ANSM) and French National Health Insurance (CNAM)), 143 Boulevard Anatole, 93200 Saint-Denis, France.

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http://dx.doi.org/10.3390/cancers11101463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827362PMC
September 2019

Mutation patterns in essential thrombocythemia, polycythemia vera and secondary myelofibrosis.

Leuk Lymphoma 2019 May 2;60(5):1289-1293. Epub 2019 Jan 2.

a Laboratoire d'Oncologie Prédictive , Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille , Inserm U1068 CNRS UMR 7258 , Marseille , France.

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http://dx.doi.org/10.1080/10428194.2018.1522437DOI Listing
May 2019

Clinical outcome of FLAG-IDA chemotherapy sequential with Flu-Bu3 conditioning regimen in patients with refractory AML: a parallel study from Shanghai Institute of Hematology and Institut Paoli-Calmettes.

Bone Marrow Transplant 2019 03 6;54(3):458-464. Epub 2018 Aug 6.

Shanghai Institute of Hematology, Department of Hematology, Blood and Marrow Transplantation Center, Collaborative Innovation Center of Hematology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, 18F/OPD Bldg 197 Rui Jin Road II, 200025, Shanghai, China.

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http://dx.doi.org/10.1038/s41409-018-0283-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462832PMC
March 2019

Evaluation of the Incidence of Hematologic Malignant Neoplasms Among Breast Cancer Survivors in France.

JAMA Netw Open 2019 01 4;2(1):e187147. Epub 2019 Jan 4.

Health Product Epidemiology Department, French National Agency for Medicines and Health Products Safety, Saint-Denis, France.

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http://dx.doi.org/10.1001/jamanetworkopen.2018.7147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484549PMC
January 2019

JAM-C Expression as a Biomarker to Predict Outcome of Patients with Acute Myeloid Leukemia-Response.

Cancer Res 2018 11 17;78(21):6342-6343. Epub 2018 Oct 17.

Aix-Marseille Univ, Inserm, CNRS, Institut Paoli-Calmettes, CRCM, Marseille, France.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-18-0834DOI Listing
November 2018

Critically ill allogenic HSCT patients in the intensive care unit: a systematic review and meta-analysis of prognostic factors of mortality.

Bone Marrow Transplant 2018 10 27;53(10):1233-1241. Epub 2018 Apr 27.

GRRR-OH-Groupe de Recherche en Réanimation Respiratoire en Onco-Hématologie, Paris, France.

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http://dx.doi.org/10.1038/s41409-018-0181-xDOI Listing
October 2018

Association between health literacy, communication and psychological distress among myelodysplastic syndromes patients.

Leuk Res 2018 10 5;73:44-50. Epub 2018 Sep 5.

Aix-Marseille Univ, APHM, INSERM, IRD, SESSTIM, "Cancer, Biomedicine & Society" Group, Hop Timone, BIOSTIC, Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2018.08.020DOI Listing
October 2018

Blurring lines between treatment intensity and patient fitness in elderly people with AML.

Authors:
Norbert Vey

Lancet Haematol 2018 09 13;5(9):e383-e384. Epub 2018 Aug 13.

Haematology Department, Institut Paoli-Calmettes, CRCM, Marseille 13009, France; Aix-Marseille University, Inserm, CNRS, Marseille, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23523026183013
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http://dx.doi.org/10.1016/S2352-3026(18)30136-4DOI Listing
September 2018

Improved Survival by Adding Lomustine to Conventional Chemotherapy for Elderly Patients With AML Without Unfavorable Cytogenetics: Results of the LAM-SA 2007 FILO Trial.

J Clin Oncol 2018 Sep 27:JCO2018787366. Epub 2018 Sep 27.

Arnaud Pigneux and Pierre-Yves Dumas, Bordeaux University Hospital, Bordeaux University, INSERM 1035; Louis-Rachid Salmi, Ariane Mineur, and Julien Asselineau, Bordeaux University Hospital, Bordeaux; Marie C. Béné, and Jacques Delaunay, Nantes University Hospital, Nantes; Caroline Bonmati, Nancy University Hospital, Nancy; Romain Guièze, Clermont-Ferrand University Hospital, Clermont Ferrand; Isabelle Luquet, Eric Delabesse, and Christian Récher, Toulouse University Hospital, Toulouse; Pascale Cornillet-Lefebvre, Reims University Hospital, Reims; Jean-Christophe Ianotto, Brest University Hospital, Brest; Mario Ojeda-Uribe, Mulhouse Regional Hospital, Mulhouse; Mathilde Hunault and Norbert Ifrah, Angers University Hospital and INSERM U 892/CNRS 6299, Angers; Anne Banos, Cote Basque General Hospital, Bayonne; Luc Matthieu Fornecker, Strasbourg University Hospital, Strasbourg; Marc Bernard, Rennes University Hospital, Rennes; Eric Jourdan, Nîmes University Hospital, Nîmes; Norbert Vey, Institut Paoli Calmettes, Marseilles; Hacene Zerazhi, Avignon General Hospital, Avignon; Yosr Hishri, Montpellier University Hospital, Montpellier; Roselyne Delepine, Tours University Hospital, Tours; and Jean-Yves Cahn, Grenoble University Hospital, Grenoble, France.

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http://dx.doi.org/10.1200/JCO.2018.78.7366DOI Listing
September 2018

Intensified Therapy of Acute Lymphoblastic Leukemia in Adults: Report of the Randomized GRAALL-2005 Clinical Trial.

J Clin Oncol 2018 08 4;36(24):2514-2523. Epub 2018 Jun 4.

Françoise Huguet, Eric Delabesse, Institut Universitaire du Cancer, Toulouse; Sylvie Chevret, Nicolas Boissel, Hervé Dombret, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP); Université Paris Diderot; Agnès Buzyn, Vahid Asnafi, Elizabeth Macintyre, Hôpital Necker, AP-HP; Université Paris Descartes, Paris; Thibaut Leguay, Centre Hospitalier Universitaire, Pessac; Xavier Thomas, Véronique Lhéritier, Hôpital Lyon-Sud, Pierre Bénite; Martine Escoffre-Barbe, Centre Hospitalier Universitaire, Rennes; Patrice Chevallier, Marie C. Béné, Centre Hospitalier Universitaire, Nantes; Mathilde Hunault, Norbert Ifrah, Centre Hospitalier Universitaire, Angers; Norbert Vey, Institut Paoli-Calmettes, Marseille; Caroline Bonmati, Centre Hospitalier Universitaire, Nancy; Stéphane Lepretre, Centre Henri Becquerel, Rouen; Jean-Pierre Marolleau, Centre Hospitalier Universitaire, Amiens; Philippe Rousselot, Centre Hospitalier, Versailles; Jean-Yves Cahn, Centre Hospitalier Universitaire Grenoble-Alpes, La Tronche, France; Thomas Pabst, Inselspital; Swiss Group for Clinical Cancer Research, Bern; and Yves Chalandon, Swiss Group for Clinical Cancer Research, Bern; Hôpital Universitaire, Geneva, Switzerland.

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http://dx.doi.org/10.1200/JCO.2017.76.8192DOI Listing
August 2018

Early preemptive ICU admission for newly diagnosed high-risk acute myeloid leukemia patients.

Leuk Res 2018 05 28;68:29-31. Epub 2018 Feb 28.

Polyvalent Intensive Care Unit, Department of Anesthesiology and Critical Care, Institut Paoli Calmettes, Marseille, France; GRRR-OH (Groupe de Recherche en Réanimation Respiratoire du patient d'Onco-Hématologie), France(1). Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2018.02.015DOI Listing
May 2018

T-cell-replete haploidentical transplantation in acute myeloid leukemia.

Exp Hematol 2018 02 17;58:5-16. Epub 2017 Nov 17.

Department of Hematology, Institut Paoli-Calmettes, Marseille, France; Aix-Marseille University UM 105, Marseille, France; Centre de Recherche en Cancérologie de Marseille, Inserm, U1068, CNRS UMR 7258, Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2017.11.001DOI Listing
February 2018

Targeting apoptosis in acute myeloid leukaemia.

Br J Cancer 2017 Oct 24;117(8):1089-1098. Epub 2017 Aug 24.

Department of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.

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http://dx.doi.org/10.1038/bjc.2017.281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674101PMC
October 2017

Phase 1 dose-escalation study of oral abexinostat for the treatment of patients with relapsed/refractory higher-risk myelodysplastic syndromes, acute myeloid leukemia, or acute lymphoblastic leukemia.

Leuk Lymphoma 2017 08 2;58(8):1880-1886. Epub 2016 Dec 2.

h Service d'Hématologie , Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole , Toulouse , France.

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http://dx.doi.org/10.1080/10428194.2016.1263843DOI Listing
August 2017

Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents.

J Clin Oncol 2017 May 28;35(14):1591-1597. Epub 2017 Mar 28.

Sophie Park, Centre Hospitalier Universitaire (CHU) Grenoble Alpes, Université Grenoble Alpes, Grenoble; Jean-François Hamel and Sylvain Thépot, CHU d'Angers; Sylvain Thépot, Université d'Angers, Institut National de la Santé et de la Recherche Médicale, Unité 1232, and LabEx IGO, Angers; Andrea Toma, CHU Henri Mondor, Assistance Publique Hôpitaux de Paris (AP-HP), Université Paris-Est Créteil; Rosa Sapena and Pierre Fenaux, CHU Saint Louis, AP-HP, Université Paris X; François Dreyfus, CHU Cochin, AP-HP, Université Paris V, Paris; Charikleia Kelaidi, CHU Avicenne, Avicenne; Odile Beyne-Rauzy, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse; Aspasia Stamatoullas, Centre Henri Becquerel, Rouen; Agnès Guerci-Bresler, CHU Nancy, Nancy; Dominique Bordessoule, CHU Dupuytren, Limoges; Pascale Cony-Makhoul, Centre Hospitalier Annecy Genevois, Epagny Metz-Tessy; Stéphane Cheze, CHU de Caen, Caen; Eric Wattel, Centre Hospitalier Lyon-Sud, Pierre Bénite, Lyon; Christian Rose, Université Catholique de Lille, Lille; Norbert Vey, Institut Paoli-Calmettes Marseille, Marseille, France; Maria Diez Campelo, Hospital Universitario de Salamanca, Salamanca; Teresa Bernal, Hospital Central de Asturias, Oviedo; Fernando Ramos, Hospital de León, León; Marisa Calabuig, Hospital Clínico de Valencia; Guillermo F. Sanz, Hospital Universitario y Politecnico La Fe, Valencia, Spain; Valeria Santini and Alessandro Sanna, Azienda Ospedaliero Universitaria (AOU) Careggi and University of Florence, Florence; Enrico Balleari, Istituto di Ricovero e Cura a Carattere Scientifico AOU San Martino di Genova, Genova; Daniela Gioia, Azienda Ospedaliera SS Antonio e Biagio e Cesare Arrigo, Alessandria; Dario Ferrero, Università degli Studi di Torino; Gianluca Gaidano, Amedeo Avogadro University of Eastern Piedmont, Torino; Giovanni Cametti, Ospedale Maggiore di Chieri, Chieri; Fabrizio Pane, Università Federico II, Napoli, Italy; Mikkael A. Sekeres and Jaime Fensterl, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH; Rami Komrokji, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David P. Steensma, Dana-Farber Cancer Institute, Boston, MA; Gail J. Roboz, Weill Medical College of Cornell University, New York, NY; Jennifer Kaivers and Ulrich Germing, University of Düsseldorf, Düsseldorf; Katharina Götze and Catharina Müller-Thomas, Universität München, München, Germany; and Ioannis Kotsianidis, Democritus University of Thrace, University Hospital of Alexandroupolis, Alexandroupolis, Greece.

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http://dx.doi.org/10.1200/JCO.2016.71.3271DOI Listing
May 2017

Treatment of Post-transplant Relapse of FLT3-ITD Mutated AML Using 5-Azacytidine and Sorafenib Bitherapy.

Clin Lymphoma Myeloma Leuk 2017 04 11;17(4):241-242. Epub 2017 Jan 11.

Hematology Department, Institut Paoli-Calmettes, Marseille, France; Aix Marseille Université, Marseille, France.

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http://dx.doi.org/10.1016/j.clml.2016.10.002DOI Listing
April 2017

Randomized Phase II Study of Clofarabine-Based Consolidation for Younger Adults With Acute Myeloid Leukemia in First Remission.

J Clin Oncol 2017 Apr 21;35(11):1223-1230. Epub 2017 Feb 21.

Xavier Thomas, Lyon-Sud University Hospital, Pierre Bénite; Stéphane de Botton, Gustave-Roussy Cancer Institute, Villejuif; Sylvie Chevret, Emmanuel Raffoux, and Hervé Dombret, Paris Saint-Louis University Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), University Paris Diderot; Olivier Hermine, Paris Necker University Hospital, AP-HP, University Paris Descartes; Karine Celli-Lebras, Acute Leukemia French Association Coordination Office, Paris Saint-Louis University Hospital, Paris; Denis Caillot, Dijon University Hospital, Dijon; Emilie Lemasle, Henri-Becquerel Cancer Center, Rouen; Jean-Pierre Marolleau, Amiens University Hospital, Amiens; Céline Berthon, Claude Huriez University Hospital; Claude Preudhomme, University of Lille, Claude Huriez University Hospital, Institut National de la Santé et de la Recherche Médicale UMR-S 1172, Jean-Pierre Aubert Research Institute, Lille; Arnaud Pigneux, Bordeaux Haut-Leveque University Hospital, Pessac; Norbert Vey, Paoli-Calmette Cancer Institute, Marseille; Oumedaly Reman, George-Clémenceau University Hospital, Caen; Marc Simon, Valenciennes Hospital, Valenciennes; Christian Recher, Toulouse Cancer University Institute, Toulouse; Jean-Yves Cahn, Grenoble University Hospital, Grenoble; Sylvie Castaigne and Christine Terré, Versailles University Hospital, Versailles-Saint Quentin University, Le Chesnay; and Norbert Ifrah, Angers University Hospital, Angers, France.

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http://dx.doi.org/10.1200/JCO.2016.70.4551DOI Listing
April 2017

Kinetics of Cytotoxic Lymphocytes Reconstitution after Induction Chemotherapy in Elderly AML Patients Reveals Progressive Recovery of Normal Phenotypic and Functional Features in NK Cells.

Front Immunol 2017 2;8:64. Epub 2017 Feb 2.

Plateforme d'Immunomonitoring en Cancérologie de Marseille, Institut Paoli-Calmettes, Marseille, France; Centre de Recherche en Cancérologie de Marseille, INSERM U1068, Institut Paoli-Calmettes, Aix-Marseille Université, UM105, CNRS, UMR7258, Marseille, France.

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http://dx.doi.org/10.3389/fimmu.2017.00064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288405PMC
February 2017

Postinduction Minimal Residual Disease Predicts Outcome and Benefit From Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia With NPM1 Mutation: A Study by the Acute Leukemia French Association Group.

J Clin Oncol 2017 Jan 14;35(2):185-193. Epub 2016 Nov 14.

Marie Balsat, Xavier Thomas, and Sandrine Hayette, Centre Hospitalier Lyon Sud, Pierre Benite; Aline Renneville, Alice Marceau, Olivier Nibourel, Céline Rodriguez, and Claude Preudhomme, CHRU of Lille; Aline Renneville, Alice Marceau, Olivier Nibourel, and Claude Preudhomme, Cancer Research Institute of Lille and Université Lille; and Céline Berthon, Claude Huriez Hospital, Lille; Stéphane de Botton, Institut Gustave Roussy, Villejuif; Denis Caillot, Dijon University Hospital, Dijon; Emilie Lemasle, Henri-Becquerel Center, Rouen; Jean-Pierre Marolleau, Amiens University Hospital, Amiens; Emmanuel Raffoux, Hervé Dombret, Jean-Michel Cayuela, Marie Magdeleine Coudé, Karine Celli-Lebras, and Nicolas Boissel, Hôpital Saint-Louis, AP-HP; Emmanuel Raffoux, Herve Dombret, and Nicolas Boissel, University 7 Paris Diderot; and Thorsten Braun, Hôpital Avicennes, AP-HP, Paris; Arnaud Pigneux, Haut-Leveque Hospital, Pessac; Norbert Vey, Paoli-Calmette Institute, Marseille; and Christine Terre, Hôpital de Versailles, Le Chesnay, France.

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http://dx.doi.org/10.1200/JCO.2016.67.1875DOI Listing
January 2017

Therapy-related acute myeloid leukemia following treatment of lymphoid malignancies.

Oncotarget 2016 Dec;7(52):85937-85947

Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France.

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http://dx.doi.org/10.18632/oncotarget.13262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349887PMC
December 2016

Predicting outcome of patients with myelodysplastic syndromes after failure of azacitidine: validation of the North American MDS consortium scoring system.

Haematologica 2016 10;101(10):e427-e428

Groupe Francophone des myélodysplasies, Hopital Saint Louis, Paris, France Service Hematologie 2, Institut Paoli-Calmettes, Marseille, France.

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http://dx.doi.org/10.3324/haematol.2016.150714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046667PMC
October 2016

Lost in translation? Ten years of development of histone deacetylase inhibitors in acute myeloid leukemia and myelodysplastic syndromes.

Expert Opin Investig Drugs 2016 ;25(3):307-17

b Department of Internal Medicine, Section of Hematology , Yale University School of Medicine , New Haven , CT , USA.

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http://dx.doi.org/10.1517/13543784.2016.1146251DOI Listing
September 2016

Epigenetically centered evolution in an example of myeloid malignancy.

Am J Hematol 2016 09 4;91(9):E361-2. Epub 2016 Jul 4.

Centre de Recherche en Cancérologie de Marseille, Laboratoire D'Oncologie Moléculaire, UMR1068 Inserm, Institut Paoli-Calmettes, CNRS UMR725, Marseille, France.

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http://dx.doi.org/10.1002/ajh.24450DOI Listing
September 2016

Randomized Phase III Study of Lenalidomide Versus Placebo in RBC Transfusion-Dependent Patients With Lower-Risk Non-del(5q) Myelodysplastic Syndromes and Ineligible for or Refractory to Erythropoiesis-Stimulating Agents.

J Clin Oncol 2016 09 27;34(25):2988-96. Epub 2016 Jun 27.

Valeria Santini, University of Florence, Florence, Italy; Antonio Almeida, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal; Aristoteles Giagounidis and Stefanie Gröpper, Marien Hospital Düsseldorf; Norbert Gattermann, Heinrich-Heine-Universität, Düsseldorf; Uwe Platzbecker, Technical University Dresden, Dresden, Germany; Anna Jonasova, Charles University General Hospital, Prague, Czech Republic; Norbert Vey, Centre Régional de Lutte Contre le Cancer, Marseille; Pierre Fenaux, Université Paris, Paris, France; Francis Séguy and Albert Hoenekopp, Celgene International, Boudry, Switzerland; Ghulam J. Mufti, King's College Hospital, London, United Kingdom; Rena Buckstein, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Moshe Mittelman and Ron Ram, Tel Aviv University; Ofer Shpilberg, Assuta Medical Center, Tel Aviv, Israel; Consuelo del Cañizo, Hospital Universitario de Salamanca, Salamanca; Alberto Risueño, Celgene Institute for Translational Research Europe, Seville, Spain; Keiya Ozawa, The University of Tokyo, Tokyo, Japan; Kyle J. MacBeth, Celgene Corporation, San Francisco, CA; and Jianhua Zhong and C.L. Beach, Celgene Corporation, Summit, NJ.

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http://dx.doi.org/10.1200/JCO.2015.66.0118DOI Listing
September 2016

Rituximab in B-Lineage Adult Acute Lymphoblastic Leukemia.

N Engl J Med 2016 Sep;375(11):1044-53

From the Département d'Hématologie, Hôpital Henri Mondor, Assistance Publique-Hôpitaux de Paris (AP-HP), Institut Mondor de Recherche Biomédicale (équipe 21), Université Paris Est, Creteil (S.M.), Service de Biostatistique (S.C.) and Département d'Hématologie (N.B., K.B., H.D.), Hôpital Saint-Louis, AP-HP, Institut Universitaire d'Hématologie, Université Paris Diderot, Paris, Département d'Hématologie (X.T.) and Group for Research on Adult Acute Lymphoblastic Leukemia Coordination Office (V.L.), Hospices Civils de Lyon, Hôpital Lyon Sud, Pierre-Bénite, Département d'Hématologie, Centre Hospitalier Universitaire (CHU) Haut-Lévêque, Pessac (T.L.), Département d'Hématologie, Institut Universitaire du Cancer, Toulouse (F.H.), Département d'Hématologie Clinique, CHU Hôtel Dieu (P.C.), and Service d'Hématologie Biologique, CHU (M.C.B.), Nantes, Département d'Hématologie, CHU, Angers (M.H., N.I.), Département d'Hématologie, CHU, Rennes (M.E.-B.), Département d'Hématologie, Institut Paoli-Calmettes, Marseille (N.V.), Département d'Hématologie, Centre Hospitalier de Dunkerque, Dunkirk (J.-M.P.), Département d'Hématologie, Hôpital Avicenne, AP-HP, Université Paris Nord, Bobigny (T.B.), Département d'Hématologie, CHU, Université Picardie Jules Verne, Amiens ( J.-P.M.), and Département d'Hématologie, CHU, Grenoble ( J.-Y.C.) - all in France; and the Klinik für Hämatologie, Universitätsspital, Basel (D.H.), Swiss Group for Clinical Cancer Research, Bern (D.H., U.H., Y.C.), Klinik für Onkologie-Hämatologie, Kantonsspital St. Gallen, St. Gallen (U.H.), and Division of Hematology, Department of Medical Specialties, University Hospital and University of Geneva, Geneva (Y.C.) - all in Switzerland.

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http://dx.doi.org/10.1056/NEJMoa1605085DOI Listing
September 2016

Awareness of acute myeloid leukaemia risk induced by diagnosis of a myelodysplastic syndrome.

Leuk Res 2016 07 4;46:79-84. Epub 2016 May 4.

Aix-Marseille Université, Inserm, IRD, UMR912, SESSTIM, "Cancers, Biomedicine & Society" group, Marseille F-13273 France; APHM, Timone Hospital, Public Health Department (BioSTIC), Marseille F-13385, France. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2016.05.001DOI Listing
July 2016

Frequency and Dynamics of Leukemia-Initiating Cells during Short-term Ex Vivo Culture Informs Outcomes in Acute Myeloid Leukemia Patients.

Cancer Res 2016 04 9;76(8):2082-6. Epub 2016 Mar 9.

Cancer Research UK, London Research Institute, The Francis Crick Institute, London, United Kingdom. Haematopoeitic Stem Cell Laboratory, The Francis Crick Institute, London, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2063DOI Listing
April 2016

Bromodomain inhibitor OTX015 in patients with acute leukaemia: a dose-escalation, phase 1 study.

Lancet Haematol 2016 Apr 18;3(4):e186-95. Epub 2016 Mar 18.

Hôpital Saint Louis, Assistance Publique-Hôpitaux de Paris, Paris, France; EA-3518, Institut Universitaire d'Hématologie, Université Paris Diderot, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/S2352-3026(15)00247-1DOI Listing
April 2016

BTN3A molecules considerably improve Vγ9Vδ2T cells-based immunotherapy in acute myeloid leukemia.

Oncoimmunology 2016 25;5(10):e1146843. Epub 2016 Apr 25.

Inserm, U1068, Centre de Recherche en Cancérologie de Marseille (CRCM), Immunity & Cancer, Institut Paoli-Calmettes, Aix-Marseille Université UM 105, CNRS UMR 7258, Marseilles, France; Inserm, U1068, CRCM, TrGET Plateforme d'Essais Précliniques, Institut Paoli-Calmettes, Aix-Marseille Université UM 105, CNRS UMR 7258, Marseilles, France; Aix-Marseille Univ, Marseilles, France.

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http://dx.doi.org/10.1080/2162402X.2016.1146843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087298PMC
April 2016

Haploidentical T Cell-Replete Transplantation with Post-Transplantation Cyclophosphamide for Patients in or above the Sixth Decade of Age Compared with Allogeneic Hematopoietic Stem Cell Transplantation from an Human Leukocyte Antigen-Matched Related or Unrelated Donor.

Biol Blood Marrow Transplant 2016 Jan 1;22(1):119-24. Epub 2015 Sep 1.

Transplant and Cellular Therapy Unit, Institut Paoli Calmettes, Marseille, France; Hematology Department, Institut Paoli Calmettes, Marseille, France; Transplant unit, Department of Hemato-oncology, Humanitas Cancer Center, Milano, Italy.

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http://dx.doi.org/10.1016/j.bbmt.2015.08.029DOI Listing
January 2016

Increased NK Cell Maturation in Patients with Acute Myeloid Leukemia.

Front Immunol 2015 6;6:564. Epub 2015 Nov 6.

Centre de Cancérologie de Marseille, Team Immunity and Cancer, INSERM, U1068, Institut Paoli-Calmettes, Aix-Marseille Université, UM 105, CNRS, UMR7258 , Marseille , France ; Centre de Cancérologie de Marseille, Systems Biology Platform, INSERM, U1068, Institut Paoli-Calmettes, Aix-Marseille Université, UM 105, CNRS, UMR7258 , Marseille , France.

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http://dx.doi.org/10.3389/fimmu.2015.00564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635854PMC
November 2015

Question prompt list responds to information needs of myelodysplastic syndromes patients and caregivers.

Leuk Res 2015 Jun 26;39(6):599-605. Epub 2015 Mar 26.

Institut Paoli-Calmettes, Marseille F-13273, France; Aix-Marseille Université, Inserm, CNRS, UM105, CRCM, Marseille, F-13273, France.

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http://dx.doi.org/10.1016/j.leukres.2015.03.011DOI Listing
June 2015

Comparison of 60 or 90 mg/m(2) of daunorubicin in induction therapy for acute myeloid leukemia with intermediate or unfavorable cytogenetics.

Am J Hematol 2015 Feb 19;90(2):E29-30. Epub 2014 Nov 19.

Hematology Department, Institut Paoli Calmettes, Marseille, France; Aix-Marseille University, Medecine Faculty, Marseille, France.

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http://dx.doi.org/10.1002/ajh.23884DOI Listing
February 2015

Prognostic significance of myelodysplasia-related changes according to the WHO classification among ELN-intermediate-risk AML patients.

Am J Hematol 2015 Jan 18;90(1):E22-4. Epub 2014 Oct 18.

Hematology Department, Institut Paoli Calmettes, Marseille, France; Aix-Marseille University, Marseille, France.

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http://dx.doi.org/10.1002/ajh.23850DOI Listing
January 2015

Reduced-toxicity conditioning prior to allogeneic stem cell transplantation improves outcome in patients with myeloid malignancies.

Haematologica 2014 Nov 1;99(11):1762-8. Epub 2014 Aug 1.

Département d'Hématologie, Institut Paoli Calmettes, Marseille, France Aix-Marseille University, Marseille, France Centre de Recherche en Cancérologie de Marseille (CRCM), Marseille, France

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http://dx.doi.org/10.3324/haematol.2014.105981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222478PMC
November 2014

Poor outcome with nonmyeloablative conditioning regimen before cord blood transplantation for patients with high-risk acute myeloid leukemia compared with matched related or unrelated donor transplantation.

Biol Blood Marrow Transplant 2014 Oct 14;20(10):1560-5. Epub 2014 Jun 14.

Hematology Department, Transplantation Program, Institut Paoli Calmettes, Marseille, France; Aix-Marseille Université, Marseille, France; Inserm UMR 1068/Centre de Recherche en Cancérologie de Marseille, Marseille, France.

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http://dx.doi.org/10.1016/j.bbmt.2014.06.006DOI Listing
October 2014

Gene mutations differently impact the prognosis of the myelodysplastic and myeloproliferative classes of chronic myelomonocytic leukemia.

Am J Hematol 2014 Jun 10;89(6):604-9. Epub 2014 Apr 10.

Centre de Recherche en Cancérologie de Marseille, Aix-Marseille University, Marseille, France; Laboratoire d'Oncologie Moléculaire, UMR1068 Inserm, CNRS UMR7258, Aix-Marseille University, Marseille, France; Institut Paoli-Calmettes, Aix-Marseille University, Marseille, France.

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http://doi.wiley.com/10.1002/ajh.23702
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http://dx.doi.org/10.1002/ajh.23702DOI Listing
June 2014

Cancer-Induced Alterations of NK-Mediated Target Recognition: Current and Investigational Pharmacological Strategies Aiming at Restoring NK-Mediated Anti-Tumor Activity.

Front Immunol 2014 24;5:122. Epub 2014 Mar 24.

Centre de Cancérologie de Marseille, INSERM, U1068, Institut Paoli-Calmettes, Aix-Marseille Université, UM 105, CNRS, UMR7258 , Marseille , France ; Centre de Cancérologie de Marseille, Plateforme d'Immunomonitoring en Cancérologie, INSERM, U1068, Institut Paoli-Calmettes, Aix-Marseille Université, UM 105, CNRS, UMR7258 , Marseille , France.

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http://dx.doi.org/10.3389/fimmu.2014.00122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970020PMC
June 2014

International randomized phase III study of elacytarabine versus investigator choice in patients with relapsed/refractory acute myeloid leukemia.

J Clin Oncol 2014 Jun 19;32(18):1919-26. Epub 2014 May 19.

Gail J. Roboz, Weill Cornell Medical College and the New York Presbyterian Hospital; Todd Rosenblat, Columbia University Medical Center, New York, NY; Martha Arellano, Winship Cancer Institute at Emory University; Scott R. Solomon, The Blood and Marrow Transplant Group of Georgia, Atlanta, GA; Jessica K. Altman, Francis J. Giles, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL; Casey O'Connell, University of Southern California Norris Comprehensive Cancer Center and Hospital, Los Angeles, CA; Marco Gobbi, Azienda Ospedaliera Universitaria San Martino, University of Genoa, Genoa, Italy; Pau Montesinos, Hospital Universitario y Politécnico La Fé, Valencia, Spain; Arnaud Pigneux, Centre Hospitalier Universitaire de Bordeaux Hôpital Haut-Lévêque, Pessac; Norbert Vey, L'Institut Paoli-Calmettes, Marseilles, France; Robert Hills, Cardiff University School of Medicine, Cardiff, United Kingdom; Tove Flem Jacobsen, Athos Gianella-Borradori, Øivind Foss, and Sylvia Vetrhus, Clavis Pharma ASA, Oslo, Norway.

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http://dx.doi.org/10.1200/JCO.2013.52.8562DOI Listing
June 2014

Preferences of older adults with cancer for involvement in decision-making about research participation.

J Am Geriatr Soc 2014 Jun;62(6):1191-3

Aix Marseille Université, Inserm, IRD, UM 62 SESSTIM, Marseille, France; Assistance Publique - Hôspitaux de Marseille, Hôpital de la Timone, BiosTIC, Marseille, France.

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http://dx.doi.org/10.1111/jgs.12820DOI Listing
June 2014

Antithymocyte globulin in reduced-intensity conditioning regimen allows a high disease-free survival exempt of long-term chronic graft-versus-host disease.

Biol Blood Marrow Transplant 2014 Mar 4;20(3):370-4. Epub 2013 Dec 4.

Hematology Department, Transplantation Program, Institut Paoli Calmettes, Marseille, France; Aix-Marseille Université, Marseille, France; Centre de Recherche en Cancérologie de Marseille (CRCM), Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2013.11.030DOI Listing
March 2014

[Myelodysplastic syndromes].

Rev Prat 2013 Dec;63(10):1445-50

Université Aix-Marseille et institut Paoli-Calmettes, 232, bd Sainte-Marguerite, 13009 Marseille, France.

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December 2013