Publications by authors named "Norbert Galldiks"

100Publications

Photopenic Defects in Gliomas With Amino-Acid PET and Relative Prognostic Value: A Multicentric 11C-Methionine and 18F-FDOPA PET Experience.

Clin Nucl Med 2020 Aug 15. Epub 2020 Aug 15.

From the Department of Nuclear Medicine and Nancyclotep Imaging Platform, Université de Lorraine.

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http://dx.doi.org/10.1097/RLU.0000000000003240DOI Listing
August 2020

Imaging findings following regorafenib in malignant gliomas: FET PET adds valuable information to anatomical MRI.

Neurooncol Adv 2019 May-Dec;1(1):vdz038. Epub 2019 Oct 20.

Institute of Neuroscience and Medicine (INM-3, -4), Research Center Juelich, Juelich, Germany.

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http://dx.doi.org/10.1093/noajnl/vdz038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212846PMC
October 2019

Highlights of the inaugural ten - the launch of Neuro-Oncology Advances.

Neurooncol Adv 2019 May-Dec;1(1):vdz016. Epub 2019 Aug 28.

Division of Neurosurgery, University Health Network and MacFeeters-Hamilton Neuro-Oncology Program, Princess Margaret Hospital, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1093/noajnl/vdz016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212904PMC
August 2019

Imaging challenges following newer treatment options: are companion diagnostics required in neurooncology?

Expert Rev Mol Diagn 2020 Jul 30;20(7):651-652. Epub 2020 Jun 30.

Institute of Neuroscience and Medicine (INM-3, -4), Research Center Juelich , Juelich, Germany.

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http://dx.doi.org/10.1080/14737159.2020.1782191DOI Listing
July 2020

Role of the default mode resting-state network for cognitive functioning in malignant glioma patients following multimodal treatment.

Neuroimage Clin 2020 26;27:102287. Epub 2020 May 26.

Institute of Neuroscience and Medicine (INM-1, -3, -4), Research Center Juelich, Wilhelm-Johnen-Str., 52428 Juelich, Germany; Department of Nuclear Medicine, University Hospital Aachen, RWTH Aachen University, Pauwelsstr. 30, 52074 Aachen, Germany.

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http://dx.doi.org/10.1016/j.nicl.2020.102287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298724PMC
May 2020

Radiomics in neuro-oncology: Basics, workflow, and applications.

Methods 2020 Jun 6. Epub 2020 Jun 6.

Institute of Neuroscience and Medicine (INM-3, -4, -11), Research Center Juelich, Wilhelm-Johnen-Str., 52428 Juelich, Germany; Center of Integrated Oncology (CIO), Universities of Aachen, Bonn, Cologne and Duesseldorf, Kerpener Str. 62, 50937 Cologne, Germany; Department of Nuclear Medicine and Comprehensive Diagnostic Center Aachen (CDCA), RWTH Aachen University, Pauwelsstr. 30, 52074 Aachen, Germany; JARA - BRAIN - Translational Medicine, Aachen, Germany.

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http://dx.doi.org/10.1016/j.ymeth.2020.06.003DOI Listing
June 2020

Applications of radiomics and machine learning for radiotherapy of malignant brain tumors.

Strahlenther Onkol 2020 Oct 11;196(10):856-867. Epub 2020 May 11.

Institute of Neuroscience and Medicine (INM-3, -4), Research Center Juelich, Wilhelm-Johnen-Straße, 52428, Juelich, Germany.

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http://dx.doi.org/10.1007/s00066-020-01626-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498494PMC
October 2020

Effect of Zolpidem in the Aftermath of Traumatic Brain Injury: An MEG Study.

Case Rep Neurol Med 2020 20;2020:8597062. Epub 2020 Mar 20.

Institute of Neuroscience and Medicine (INM-4), Medical Imaging Physics, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.

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http://dx.doi.org/10.1155/2020/8597062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109561PMC
March 2020

MRI Follow-up of Astrocytoma: Automated Coregistration and Color-Coding of FLAIR Sequences Improves Diagnostic Accuracy With Comparable Reading Time.

J Magn Reson Imaging 2020 Oct 4;52(4):1197-1206. Epub 2020 Apr 4.

Institute for Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1002/jmri.27136DOI Listing
October 2020

Current Landscape and Emerging Fields of PET Imaging in Patients with Brain Tumors.

Molecules 2020 Mar 24;25(6). Epub 2020 Mar 24.

Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener St. 62, 50937 Cologne, Germany.

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http://dx.doi.org/10.3390/molecules25061471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146177PMC
March 2020

PET/MRI Radiomics in Patients With Brain Metastases.

Front Neurol 2020 7;11. Epub 2020 Feb 7.

Institute of Neuroscience and Medicine (INM-3/-4/-11), Research Center Juelich, Jülich, Germany.

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http://dx.doi.org/10.3389/fneur.2020.00001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020230PMC
February 2020

Current trends in the use of O-(2-[F]fluoroethyl)-L-tyrosine ([F]FET) in neurooncology.

Nucl Med Biol 2020 Feb 19. Epub 2020 Feb 19.

Institute of Neuroscience and Medicine (INM-3, INM-4, INM-5), Forschungszentrum Juelich, Juelich, Germany; Dept. of Nuclear Medicine, RWTH University Hospital, Aachen, Germany; Juelich-Aachen Research Alliance (JARA) - Section JARA-Brain, Germany; Center of Integrated Oncology (CIO), University of Aachen, Bonn, Cologne and Duesseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nucmedbio.2020.02.006DOI Listing
February 2020

Leptomeningeal Carcinomatosis in a Patient with Pancreatic Cancer Responding to Nab-Paclitaxel plus Gemcitabine.

Case Rep Oncol 2020 Jan-Apr;13(1):35-42. Epub 2020 Jan 21.

Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1159/000504697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011711PMC
January 2020

Flare Phenomenon in -(2-F-Fluoroethyl)-l-Tyrosine PET After Resection of Gliomas.

J Nucl Med 2020 Sep 31;61(9):1294-1299. Epub 2020 Jan 31.

Institute of Neuroscience and Medicine (INM-3, INM-4, and INM-5), Forschungszentrum Jülich, Jülich, Germany

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http://dx.doi.org/10.2967/jnumed.119.238568DOI Listing
September 2020

Combined FET PET/ADC mapping: improved imaging of glioma infiltration?

Neuro Oncol 2020 03;22(3):313-314

Institute of Neuroscience and Medicine, Research Center Juelich,Juelich, Germany.

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http://dx.doi.org/10.1093/neuonc/noz236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058440PMC
March 2020

Molecular imaging and advanced MRI findings following immunotherapy in patients with brain tumors.

Expert Rev Anticancer Ther 2020 01 23;20(1):9-15. Epub 2019 Dec 23.

Institute of Neuroscience and Medicine (INM-3, -4), Research Center Juelich, Jülich, Germany.

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http://dx.doi.org/10.1080/14737140.2020.1705788DOI Listing
January 2020

Advantages and limitations of amino acid PET for tracking therapy response in glioma patients.

Expert Rev Neurother 2020 02 18;20(2):137-146. Epub 2019 Dec 18.

Institute of Neuroscience and Medicine (INM-3, INM-4), Forschungszentrum Juelich, Juelich, Germany.

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http://dx.doi.org/10.1080/14737175.2020.1704256DOI Listing
February 2020

F-FET PET Imaging in Differentiating Glioma Progression from Treatment-Related Changes: A Single-Center Experience.

J Nucl Med 2020 04 13;61(4):505-511. Epub 2019 Sep 13.

Institute of Neuroscience and Medicine (INM-3 and INM-4), Research Center Juelich, Juelich, Germany.

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http://dx.doi.org/10.2967/jnumed.119.234757DOI Listing
April 2020

Comment on "Hypometabolic gliomas on FET-PET-is there an inverted U-curve for survival?"

Neuro Oncol 2019 12;21(12):1612-1613

Department of Nuclear Medicine, University Hospital, Ludwig Maximilians University of Munich, Munich, Germany.

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http://dx.doi.org/10.1093/neuonc/noz173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917398PMC
December 2019

Dynamic FET PET Imaging of a "Butterfly" IDH-Wildtype Anaplastic Astrocytoma.

Clin Nucl Med 2019 Oct;44(10):e581-e582

Institute of Neuroscience and Medicine, Research Center Jülich, Jülich, Germany.

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http://dx.doi.org/10.1097/RLU.0000000000002740DOI Listing
October 2019

Differentiation of treatment-related changes from tumour progression: a direct comparison between dynamic FET PET and ADC values obtained from DWI MRI.

Eur J Nucl Med Mol Imaging 2019 Aug 15;46(9):1889-1901. Epub 2019 Jun 15.

Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1007/s00259-019-04384-7DOI Listing
August 2019

Current status of PET imaging in neuro-oncology.

Neurooncol Adv 2019 May-Dec;1(1):vdz010. Epub 2019 May 28.

Department of Nuclear Medicine, University Hospital Aachen, Aachen, Germany.

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http://dx.doi.org/10.1093/noajnl/vdz010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324052PMC
May 2019

Comparison of [F]Fluoroethyltyrosine PET and Sodium MRI in Cerebral Gliomas: a Pilot Study.

Mol Imaging Biol 2020 02;22(1):198-207

Institute of Neuroscience and Medicine (3, 4, 5, 11), Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.

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http://dx.doi.org/10.1007/s11307-019-01349-yDOI Listing
February 2020

Magnetic Resonance Imaging Reveals a Pronounced Treatment Response of a Isocitrate Dehydrogenase- and B-Raf Proto-Oncogene-Wildtype Epithelioid Glioblastoma.

World Neurosurg 2019 Jul 8;127:213-215. Epub 2019 Apr 8.

Department of Neurology, Faculty of Medicine and University Hospital Cologne, Cologne, Germany; Institute of Neuroscience and Medicine (INM-3), Forschungszentrum Juelich, Juelich, Germany; Center of Integrated Oncology (CIO), University of Cologne, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.wneu.2019.04.025DOI Listing
July 2019

Combined Amino Acid Positron Emission Tomography and Advanced Magnetic Resonance Imaging in Glioma Patients.

Cancers (Basel) 2019 Jan 29;11(2). Epub 2019 Jan 29.

Institute of Neuroscience and Medicine (INM-3, -4, -5, -11), Forschungszentrum Juelich, 52425 Juelich, Germany.

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http://dx.doi.org/10.3390/cancers11020153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406895PMC
January 2019

Monitoring Treatment Response to Erlotinib in EGFR-mutated Non-small-cell Lung Cancer Brain Metastases Using Serial O-(2-[F]fluoroethyl)-L-tyrosine PET.

Clin Lung Cancer 2019 03 5;20(2):e148-e151. Epub 2018 Nov 5.

Lung Cancer Group Cologne, Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany; Center for Integrated Oncology Köln, Bonn, Germany; Network Genomic Medicine (NGM) Lung Cancer, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2018.10.011DOI Listing
March 2019

FET PET reveals considerable spatial differences in tumour burden compared to conventional MRI in newly diagnosed glioblastoma.

Eur J Nucl Med Mol Imaging 2019 03 16;46(3):591-602. Epub 2018 Oct 16.

Institute of Neuroscience and Medicine (INM-3, -4, -5), Forschungszentrum Juelich, 52425, Juelich, Germany.

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http://dx.doi.org/10.1007/s00259-018-4188-8DOI Listing
March 2019

Extracranial Metastases of a Cerebral Glioblastoma: A Case Report and Review of the Literature.

Case Rep Oncol 2018 May-Aug;11(2):591-600. Epub 2018 Aug 28.

Department of Neurology, University of Cologne, Cologne, Germany.

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https://www.karger.com/Article/FullText/492111
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http://dx.doi.org/10.1159/000492111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167720PMC
August 2018

Combined FET PET/MRI radiomics differentiates radiation injury from recurrent brain metastasis.

Neuroimage Clin 2018 19;20:537-542. Epub 2018 Aug 19.

Inst. of Neuroscience and Medicine (INM-3, -4, -5), Forschungszentrum Juelich, Juelich, Germany; Dept. of Neurology, University of Cologne, Cologne, Germany; Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Cologne, Germany.

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http://dx.doi.org/10.1016/j.nicl.2018.08.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118093PMC
January 2019

FET PET in Primary Central Nervous System Vasculitis.

Clin Nucl Med 2018 Sep;43(9):e322-e323

Stereotactic and Functional Neurosurgery, University Hospital Cologne, Cologne.

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http://dx.doi.org/10.1097/RLU.0000000000002197DOI Listing
September 2018

Correlation of Dynamic O-(2-[F]Fluoroethyl)-L-Tyrosine Positron Emission Tomography, Conventional Magnetic Resonance Imaging, and Whole-Brain Histopathology in a Pretreated Glioblastoma: A Postmortem Study.

World Neurosurg 2018 Nov 2;119:e653-e660. Epub 2018 Aug 2.

Institute of Neuroscience and Medicine (INM-1, -3, -4, -11), Forschungszentrum Juelich, Juelich, Germany; Department of Nuclear Medicine, University Hospital RWTH Aachen, Aachen, Germany.

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http://dx.doi.org/10.1016/j.wneu.2018.07.232DOI Listing
November 2018

Update on amino acid PET of brain tumours.

Curr Opin Neurol 2018 08;31(4):354-361

Institute of Neuroscience and Medicine (INM-3, INM-4) Forschungszentrum Jülich, Jülich.

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http://dx.doi.org/10.1097/WCO.0000000000000574DOI Listing
August 2018

The Treatment of Gliomas in Adulthood.

Dtsch Arztebl Int 2018 05;115(20-21):356-364

Joint last authors; Center for Neurosurgery, Department of Neurosurgery, University Hospital Cologne; Center for Neurosurgery, Department of Stereotactic and Functional Neurosurgery, University Hospital Cologne; Center for Neurosurgery, Department of Stereotactic and Functional Neurosurgery, former Department of Radiotherapy and Radiooncology, University Hospital Cologne; Center for Neurosurgery, Department of Neurosurgery, University Hospital Cologne; Department of Neurology, University Hospital Cologne; Institute of Neuroscience and Medicine (INM-3), Forschungszentrum Jülich; Center for Neurosurgery, Department of Neurosurgery, University Hospital Cologne.

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http://dx.doi.org/10.3238/arztebl.2018.0356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172648PMC
May 2018

Investigational PET tracers for high-grade gliomas.

Q J Nucl Med Mol Imaging 2018 Sep 4;62(3):281-294. Epub 2018 Jun 4.

Department of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA -

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http://dx.doi.org/10.23736/S1824-4785.18.03105-9DOI Listing
September 2018

Radiomics derived from amino-acid PET and conventional MRI in patients with high-grade gliomas.

Q J Nucl Med Mol Imaging 2018 Sep 4;62(3):272-280. Epub 2018 Jun 4.

Institute of Neuroscience and Medicine (INM-3, -4), Forschungszentrum Juelich, Juelich, Germany.

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http://dx.doi.org/10.23736/S1824-4785.18.03095-9DOI Listing
September 2018

Influence of Dexamethasone on O-(2-[F]-Fluoroethyl)-L-Tyrosine Uptake in the Human Brain and Quantification of Tumor Uptake.

Mol Imaging Biol 2019 02;21(1):168-174

Institute of Neuroscience and Medicine (INM-3, INM-4; INM-5; INM-11), Forschungszentrum Jülich, 52425, Jülich, Germany.

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http://dx.doi.org/10.1007/s11307-018-1221-zDOI Listing
February 2019

Neuroimaging in patients with high-grade gliomas.

Authors:
Norbert Galldiks

Q J Nucl Med Mol Imaging 2018 09 16;62(3):221-224. Epub 2018 May 16.

Department of Neurology, University of Cologne, Cologne, Germany -

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http://dx.doi.org/10.23736/S1824-4785.18.03102-3DOI Listing
September 2018

Functional magnetic resonance imaging in glioma patients: from clinical applications to future perspectives.

Q J Nucl Med Mol Imaging 2018 Sep 14;62(3):295-302. Epub 2018 May 14.

Department of Neurology, University of Cologne, Cologne, Germany.

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https://www.minervamedica.it/index2.php?show=R39Y2018N03A029
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http://dx.doi.org/10.23736/S1824-4785.18.03101-1DOI Listing
September 2018

The role of amino-acid PET in the light of the new WHO classification 2016 for brain tumors.

Q J Nucl Med Mol Imaging 2018 Sep 26;62(3):267-271. Epub 2018 Apr 26.

Department of Neurology, University Hospital Cologne, Cologne, Germany.

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https://www.minervamedica.it/index2.php?show=R39Y2018N03A026
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http://dx.doi.org/10.23736/S1824-4785.18.03090-XDOI Listing
September 2018

Investigation of cis-4-[F]Fluoro-D-Proline Uptake in Human Brain Tumors After Multimodal Treatment.

Mol Imaging Biol 2018 12;20(6):1035-1043

Institute of Neuroscience and Medicine (INM-3, -4, -5), Forschungszentrum Jülich, 52425, Jülich, Germany.

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http://dx.doi.org/10.1007/s11307-018-1197-8DOI Listing
December 2018

Comparison of O-(2-F-Fluoroethyl)-L-Tyrosine Positron Emission Tomography and Perfusion-Weighted Magnetic Resonance Imaging in the Diagnosis of Patients with Progressive and Recurrent Glioma: A Hybrid Positron Emission Tomography/Magnetic Resonance Study.

World Neurosurg 2018 May 3;113:e727-e737. Epub 2018 Mar 3.

Institute of Neuroscience and Medicine (INM-3, -4), Forschungszentrum Jülich, Jülich, Germany; Department of Nuclear Medicine, RWTH Aachen University Hospital, Aachen, Germany; Section JARA-Brain, Jülich-Aachen Research Alliance (JARA), Jülich, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183041
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http://dx.doi.org/10.1016/j.wneu.2018.02.139DOI Listing
May 2018

Evaluation of factors influencing F-FET uptake in the brain.

Neuroimage Clin 2018 8;17:491-497. Epub 2017 Nov 8.

Institute of Neuroscience and Medicine (INM-1, -3, -4, -7), Forschungszentrum Jülich, Jülich, Germany.

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http://dx.doi.org/10.1016/j.nicl.2017.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684535PMC
June 2018

AIDS-Related Central Nervous System Toxoplasmosis With Increased 18F-Fluoroethyl-L-Tyrosine Amino Acid PET Uptake Due to LAT1/2 Expression of Inflammatory Cells.

Clin Nucl Med 2017 Dec;42(12):e506-e508

From the *Department of Neurology 1, NeuroMed Campus, Kepler University Hospital, Linz, Austria; †Department of Neurology, ‡Wilhelm Sander Neurooncology Unit, and Departments of §Neuropathology and ∥Nuclear Medicine, University of Regensburg Medical School, Regensburg; ¶Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich; **Department of Neurology, University of Cologne, Cologne; ††Center of Integrated Oncology, Universities of Cologne and Bonn, Cologne; and ‡‡Department of Nuclear Medicine, University of Aachen, Aachen, Germany.

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http://dx.doi.org/10.1097/RLU.0000000000001873DOI Listing
December 2017

Static and dynamic F-FET PET for the characterization of gliomas defined by IDH and 1p/19q status.

Eur J Nucl Med Mol Imaging 2018 03 17;45(3):443-451. Epub 2017 Oct 17.

Institute of Neuroscience and Medicine (INM-3, INM-4, INM-5), Forschungszentrum Jülich, Jülich, Germany.

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http://dx.doi.org/10.1007/s00259-017-3846-6DOI Listing
March 2018

Pseudoprogression after glioma therapy: an update.

Expert Rev Neurother 2017 Nov 7;17(11):1109-1115. Epub 2017 Sep 7.

b Institute of Neuroscience and Medicine , Forschungszentrum Jülich , Jülich , Germany.

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http://dx.doi.org/10.1080/14737175.2017.1375405DOI Listing
November 2017

Positron emission tomography imaging in diffuse intrinsic pontine glioma.

Ann Transl Med 2017 Aug;5(15):312

Institute of Neuroscience and Medicine (INM-3, 4), Research Center Juelich, Juelich, Germany.

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http://dx.doi.org/10.21037/atm.2017.05.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555994PMC
August 2017

Comparison of F-FET PET and perfusion-weighted MRI for glioma grading: a hybrid PET/MR study.

Eur J Nucl Med Mol Imaging 2017 Dec 22;44(13):2257-2265. Epub 2017 Aug 22.

Institute of Neuroscience and Medicine (INM-3, -4), Forschungszentrum Jülich, D-52425, Jülich, Germany.

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http://dx.doi.org/10.1007/s00259-017-3812-3DOI Listing
December 2017

Amino acid PET and MR perfusion imaging in brain tumours.

Clin Transl Imaging 2017 13;5(3):209-223. Epub 2017 Mar 13.

Institute of Neuroscience and Medicine (INM-3, INM-4), Forschungszentrum Jülich, Jülich, Germany.

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http://dx.doi.org/10.1007/s40336-017-0225-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487907PMC
March 2017

Feasibility, Risk Profile and Diagnostic Yield of Stereotactic Biopsy in Children and Young Adults with Brain Lesions.

Klin Padiatr 2017 May 30;229(3):133-141. Epub 2017 May 30.

Department of Stereotaxy and Functional Neurosurgery, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1055/s-0043-101908DOI Listing
May 2017

Imaging of amino acid transport in brain tumours: Positron emission tomography with O-(2-[F]fluoroethyl)-L-tyrosine (FET).

Methods 2017 11 24;130:124-134. Epub 2017 May 24.

Institute of Neuroscience and Medicine (INM-3, INM-4, INM-5), Forschungszentrum Juelich, Juelich, Germany; Dept. of Neurology, University of Cologne, Cologne, Germany; Centre of Integrated Oncology (CIO), University of Cologne, Cologne, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S10462023163031
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http://dx.doi.org/10.1016/j.ymeth.2017.05.019DOI Listing
November 2017

Diagnostic challenges in meningioma.

Neuro Oncol 2017 Nov;19(12):1588-1598

University Medical Center, Neurology, and Neurooncology, German Cancer Research Center and German Consortium for Translational Cancer Research, Heidelberg, Germany; Medical University Innsbruck, Department of Neurology, Innsbruck, Austria; Institute of Neuroscience and Medicine, Research Center Jülich, Jülich, Germany; Department of Neurology, University of Cologne, Cologne, Germany; Center of Integrated Oncology, Universities of Cologne and Bonn, Cologne, Germany; University Medical Center, Neuroradiology, Heidelberg, Germany; University Medical Center, Neuropathology, Heidelberg, Germany; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1093/neuonc/nox101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716093PMC
November 2017

Advances in neuro-oncology imaging.

Nat Rev Neurol 2017 May 7;13(5):279-289. Epub 2017 Apr 7.

Institute of Neuroscience and Medicine (INM-3, INM-4) Forschungszentrum Jülich, Wilhelm-Johnen-Strasse, D-52425 Jülich, Germany.

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http://dx.doi.org/10.1038/nrneurol.2017.44DOI Listing
May 2017

Amino acid PET in neuro-oncology: applications in the clinic.

Expert Rev Anticancer Ther 2017 05 11;17(5):395-397. Epub 2017 Mar 11.

b Institute of Neuroscience and Medicine, Research Center Jülich , Jülich , Germany.

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http://dx.doi.org/10.1080/14737140.2017.1302799DOI Listing
May 2017

O-(2-18F-fluoroethyl)-L-tyrosine PET for evaluation of brain metastasis recurrence after radiotherapy: an effectiveness and cost-effectiveness analysis.

Neuro Oncol 2017 Sep;19(9):1271-1278

Department of Nuclear Medicine, University of Aachen, Aachen, Germany; Institute for Health Economics and Clinical Epidemiology, University of Cologne, Cologne, Germany; Department of Conservative Dentistry, Periodontology and Preventive Dentistry, University of Aachen, Aachen, Germany; Department of Neurology, University of Cologne, Cologne, Germany; Institute for Neuroscience and Medicine, Research Center Juelich, Juelich, Germany; Department of Neuroradiology University of Aachen, Aachen, Germany; Department of Radiation Oncology, University of Cologne, Cologne, Germany; Department of Radiology, University of Bonn, Bonn, Germany; Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Germany.

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http://dx.doi.org/10.1093/neuonc/now310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570232PMC
September 2017

Influence of Bevacizumab on Blood-Brain Barrier Permeability and -(2-F-Fluoroethyl)-l-Tyrosine Uptake in Rat Gliomas.

J Nucl Med 2017 05 2;58(5):700-705. Epub 2017 Feb 2.

Institute of Neuroscience and Medicine (INM-3, INM-4, INM-5, INM-11), Forschungszentrum Jülich, Jülich, Germany

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http://dx.doi.org/10.2967/jnumed.116.187047DOI Listing
May 2017

The use of amino acid PET and conventional MRI for monitoring of brain tumor therapy.

Neuroimage Clin 2017 18;13:386-394. Epub 2016 Dec 18.

Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany; Dept. of Nuclear Medicine, University of Aachen, Aachen, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S22131582163025
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http://dx.doi.org/10.1016/j.nicl.2016.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226808PMC
November 2017

Influence of blood-brain barrier permeability on O-(2-F-fluoroethyl)-L-tyrosine uptake in rat gliomas.

Eur J Nucl Med Mol Imaging 2017 Mar 9;44(3):408-416. Epub 2016 Sep 9.

Forschungszentrum Jülich, Institute of Neuroscience and Medicine, D-52425, Jülich, Germany.

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http://dx.doi.org/10.1007/s00259-016-3508-0DOI Listing
March 2017

Dynamic O-(2-[18F]fluoroethyl)-L-tyrosine PET imaging for the detection of checkpoint inhibitor-related pseudoprogression in melanoma brain metastases.

Neuro Oncol 2016 10 2;18(10):1462-4. Epub 2016 Sep 2.

Division of Clinical Neurooncology, Department of Neurology, University of Bonn Medical Center, Bonn, Germany (S.K., M.G., U.H.); Stem Cell Pathologies Group, Institute of Reconstructive Neurobiology, Bonn, Germany (S.K., L.R, B.S., M.G.); Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Germany (S.K., N.G., M.S., U.H., M.G.); Department of Neurology, University of Cologne, Cologne, Germany (N.G.), Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany (N.G., K-J.L.); Department of Dermatology, University of Cologne, Cologne, Germany (M.S.); Neuroradiology, Department of Radiology, University of Bonn Medical Center, Bonn, Germany (E.H.); Laboratory of Experimental Dermatology, Department of Dermatology and Allergy, University of Bonn Medical Center, Bonn, Germany (J.L.); Department of Nuclear Medicine, University of Bonn Medical Center, Bonn, Germany (R.A.B.); Dept. of Nuclear Medicine, University of Aachen, Aachen, Germany (K-J.L.); DKFZ-Division of Translational Oncology / Neurooncology, German Cancer Consortium (DKTK) & University Hospital Essen, Essen, Germany (B.S.); Clinical Cooperation Unit Neurooncology, MediClin Robert Janker Klinik, Bonn, Germany (M.G.)

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http://dx.doi.org/10.1093/neuonc/now154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035529PMC
October 2016

Amino Acid PET - An Imaging Option to Identify Treatment Response, Posttherapeutic Effects, and Tumor Recurrence?

Front Neurol 2016 28;7:120. Epub 2016 Jul 28.

Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany; Department of Nuclear Medicine, University of Aachen, Aachen, Germany.

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http://dx.doi.org/10.3389/fneur.2016.00120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963389PMC
August 2016

Suspected new-onset autoimmune temporal lobe epilepsy with amygdala enlargement.

Epilepsia 2016 09 15;57(9):1485-94. Epub 2016 Jul 15.

Department of Epileptology, University of Bonn, Bonn, Germany.

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http://dx.doi.org/10.1111/epi.13471DOI Listing
September 2016

Long-term analysis of the NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with PCV or temozolomide.

Neuro Oncol 2016 11 1;18(11):1529-1537. Epub 2016 Jul 1.

Department of Neurology Clinic, University of Heidelberg, Heidelberg, Germany (W.W., A.W., M.P., B.W.); Clinical Cooperation Unit (CCU Neurooncology), German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany (W.W., B.W.); Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland (P.R., C.H., M.W.); Department of Neuropathology, Hannover Medical School, Hannover, Germany (C.H.); Department of Neurology, Regensburg University, Regensburg, Germany (P.H.); Department of Neurosurgery Clinic, Hannover Medical School, Hannover, Germany (M.N.); Department of Neurosurgery Clinic, Charité, Berlin, Germany (F.S., P.V.); Department of Neurosurgery, Heinrich Heine University, Düsseldorf, Germany (M.C.S.); Department of Neurology Clinic, Essen Medical Center, Essen, Germany (S.K.); Department of Neurosurgery Clinic, Saarland University, Homburg, Germany (R.K.); Department of Neurosurgery Clinic, University of Göttingen, Göttingen, Germany (F.S.); Department of Neurosurgery Clinic, University of Erlangen, Erlangen, Germany (I.E.); Department of Neurosurgery Clinic, University of Jena, Jena, Germany (R.K.); Department of Neurology Clinic, Cologne University, Cologne, Germany (N.G.); Department of Neurology Clinic, TU Munich, Munich, Germany (F.S.-G.); Department of Neuropathology, University of Heidelberg, Heidelberg, Germany (A.v.D.); CCU Neuropathology, (C.H., A.v.D.); CCU Brain Tumor Immunology, DKFZ, all Heidelberg, Germany (M.P.); Department of Neuropathology, Heinrich Heine University, Düsseldorf, Germany (G.R.); DKTK partner site Essen/Düsseldorf, Düsseldorf, Germany (G.R.), Department of General Neurology, Tübingen, Germany (W.W., A.W., F.S.-G., M.P., M.W.), Department of Radiation Oncology, Tübingen, Germany (M.B.), Department of Medical Biometry, University Hospital Tübingen, Tübingen, Germany (C.M.).

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http://dx.doi.org/10.1093/neuonc/now133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063521PMC
November 2016

Letter to the Editor: "Comparing the Volume of Brain Metastases in F-18-FET-PET and MRI".

World Neurosurg 2016 05;89:722

Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany; Department of Neurology, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1016/j.wneu.2015.10.084DOI Listing
May 2016

Response Assessment in Neuro-Oncology working group and European Association for Neuro-Oncology recommendations for the clinical use of PET imaging in gliomas.

Neuro Oncol 2016 09 21;18(9):1199-208. Epub 2016 Apr 21.

Department of Nuclear Medicine, Ludwig-Maximilians-University Munich, Munich, Germany (N.L.A.); Department of Neurology, University Hospital Zurich, Zurich, Switzerland (M.W.); Department of Neurosurgery, Ludwig-Maximilians-University Munich, Munich, Germany (B.S., J.C.T.); Institute of Neuroscience and Medicine, Research Center Juelich, Juelich, Germany (N.G.); Department of Neurology, University of Cologne, Cologne, Germany (N.G.); Department of Neuro-Oncology, University of Turin, Turin, Italy (R.S.); Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan (M.M.K.); Division of Nuclear Medicine and Clinical Molecular Imaging, Department of Radiology, University of Tübingen, Tübingen, Germany (C.l.F.); Radiological Sciences, University of California Los Angeles, Los Angeles, California (W.P.); Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark (I.L.); Department of Nuclear Medicine, Clínica Universidad de Navarra, University of Navarra, Pamplona, Spain (J.A.); Department of Neurology, University of Washington, Seattle, Washington (M.C.); Department of Neurological Surgery, Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, Ohio (M.A.V.); Department of Radiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California (B.M.E.)

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http://dx.doi.org/10.1093/neuonc/now058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999003PMC
September 2016

Late Pseudoprogression in Glioblastoma: Diagnostic Value of Dynamic O-(2-[18F]fluoroethyl)-L-Tyrosine PET.

Clin Cancer Res 2016 05 16;22(9):2190-6. Epub 2015 Dec 16.

Division of Clinical Neurooncology, Department of Neurology, University of Bonn Medical Centre, Bonn, Germany. Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Bonn, Germany.

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http://clincancerres.aacrjournals.org/content/early/2016/02/
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-15-1334DOI Listing
May 2016

Amino acid positron emission tomography to monitor chemotherapy response and predict seizure control and progression-free survival in WHO grade II gliomas.

Neuro Oncol 2016 05 17;18(5):744-51. Epub 2015 Nov 17.

Department of Neurology and Brain Tumor Center, Cantonal Hospital, Aarau, Switzerland (U.R.); Institute for Pharmacology and Toxicology, ETH and University of Zürich, Zürich, Switzerland (M.T.W.); Neuroscience Center, ETH and University of Zürich, Zürich, Switzerland (M.T.W.); Department of Neurology, Medical University, Innsbruck, Austria (M.N.); Department of Neuro-Oncology, University Hospital, Torino, Italy (R.R., R.S.); Department of Neurology, University Hospital, Switzerland (P.R., M.W.); Department of Oncology, University Hospital, Zürich, Switzerland (S.H.); Department of Neurology, University Hospital, Cologne, Germany, and Research Center, Jülich, Germany (N.G.); Medicina Nucleare, Istituto Nazionale dei Tumori, Milano, Italy (F.C.).

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http://dx.doi.org/10.1093/neuonc/nov282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827046PMC
May 2016

From the clinician's point of view - What is the status quo of positron emission tomography in patients with brain tumors?

Neuro Oncol 2015 Nov 30;17(11):1434-44. Epub 2015 Jun 30.

Department of Neurology, University of Cologne, Cologne, Germany (N.G.); Research Center Jülich, Institute of Neuroscience and Medicine, Jülich, Germany (N.G., K.-J.L.); Center of Integrated Oncology (CIO), University of Cologne, Cologne, Germany (N.G.); Department of Nuclear Medicine, University of Aachen, Germany (K.-J.L.); Department of Radiological Sciences, David Geffen School of Medicine at UCLA., Los Angeles (W.B.P.).

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http://dx.doi.org/10.1093/neuonc/nov118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648307PMC
November 2015