Nora Hunter

Nora Hunter

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Nora Hunter

Nora Hunter

Publications by authors named "Nora Hunter"

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BSE infectivity survives burial for five years with only limited spread.

Arch Virol 2019 Apr 24;164(4):1135-1145. Epub 2019 Feb 24.

The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, Scotland, UK.

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http://dx.doi.org/10.1007/s00705-019-04154-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420460PMC
April 2019

Archival search for historical atypical scrapie in sheep reveals evidence for mixed infections.

J Gen Virol 2015 Oct 14;96(10):3165-78. Epub 2015 Aug 14.

1​ The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.

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http://dx.doi.org/10.1099/jgv.0.000234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410109PMC
October 2015

Evidence in sheep for pre-natal transmission of scrapie to lambs from infected mothers.

PLoS One 2013 18;8(11):e79433. Epub 2013 Nov 18.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079433PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832582PMC
July 2014

Structural effects of PrP polymorphisms on intra- and interspecies prion transmission.

Proc Natl Acad Sci U S A 2014 Jul 17;111(30):11169-74. Epub 2014 Jul 17.

Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky, Lexington, KY 40506;Prion Research Center and Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523;

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http://dx.doi.org/10.1073/pnas.1404739111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121815PMC
July 2014

Presence of subclinical infection in gene-targeted human prion protein transgenic mice exposed to atypical bovine spongiform encephalopathy.

J Gen Virol 2013 Dec 17;94(Pt 12):2819-27. Epub 2013 Sep 17.

Neurobiology Division, Roslin Institute and R(D)SVS, University of Edinburgh, Roslin, Midlothian, UK.

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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.052738-0DOI Listing
December 2013

Epigenetic dominance of prion conformers.

PLoS Pathog 2013 Oct 31;9(10):e1003692. Epub 2013 Oct 31.

Prion Research Center (PRC) and Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America ; Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky, Lexington, Kentucky, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1003692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814339PMC
October 2013

Characterization of an unusual transmissible spongiform encephalopathy in goat by transmission in knock-in transgenic mice.

J Gen Virol 2013 Aug 29;94(Pt 8):1922-32. Epub 2013 May 29.

Neurobiology Division, The Roslin Institute and R(D)SVS, University of Edinburgh, Roslin, Midlothian EH25 9RG, UK.

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http://dx.doi.org/10.1099/vir.0.051706-0DOI Listing
August 2013

Susceptibility of young sheep to oral infection with bovine spongiform encephalopathy decreases significantly after weaning.

J Virol 2012 Nov 22;86(21):11856-62. Epub 2012 Aug 22.

Neurobiology Division, The Roslin Institute and R(D)SVS, University of Edinburgh, Roslin, Midlothian, United Kingdom.

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http://dx.doi.org/10.1128/JVI.01573-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486293PMC
November 2012

Characterization of conformation-dependent prion protein epitopes.

J Biol Chem 2012 Oct 4;287(44):37219-32. Epub 2012 Sep 4.

Prion Research Center, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado 80523, USA.

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http://dx.doi.org/10.1074/jbc.M112.395921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481321PMC
October 2012

Differentiating ovine BSE from CH1641 scrapie by serial protein misfolding cyclic amplification.

Mol Biotechnol 2012 Jul;51(3):233-9

School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, College Road, Sutton Bonington, Leicestershire LE12 5RD, UK.

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http://link.springer.com/10.1007/s12033-011-9460-0
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http://dx.doi.org/10.1007/s12033-011-9460-0DOI Listing
July 2012

Transcriptional profiling of peripheral lymphoid tissue reveals genes and networks linked to SSBP/1 scrapie pathology in sheep.

Vet Microbiol 2011 Dec 26;153(3-4):218-28. Epub 2011 May 26.

The Roslin Institute & R(D)SVS, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.

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http://dx.doi.org/10.1016/j.vetmic.2011.05.036DOI Listing
December 2011

Increased susceptibility of human-PrP transgenic mice to bovine spongiform encephalopathy infection following passage in sheep.

J Virol 2011 Feb 17;85(3):1174-81. Epub 2010 Nov 17.

Neuropathogenesis Division, The Roslin Institute and R(D)SVS, University of Edinburgh, Roslin, Midlothian EH25 9PS, United Kingdom.

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http://dx.doi.org/10.1128/JVI.01578-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020518PMC
February 2011

Gene expression analysis in distinct regions of the central nervous system during the development of SSBP/1 sheep scrapie.

Vet Microbiol 2011 Jan 9;147(1-2):42-8. Epub 2010 Jun 9.

Division of Infection & Immunity, The Roslin Institute & R(D)SVS, University of Edinburgh, Summerhall, Edinburgh EH9 1QH, UK.

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http://dx.doi.org/10.1016/j.vetmic.2010.05.043DOI Listing
January 2011

Identification of adjacent binding sites for the YY1 and E4BP4 transcription factors in the ovine PrP (Prion) gene promoter.

J Biol Chem 2009 Mar 7;284(11):6716-24. Epub 2009 Jan 7.

Roslin Institute and R(D)SVS, Neuropathogenesis Division, University of Edinburgh, Roslin, Midlothian EH25 9PS, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M807065200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652306PMC
March 2009

Atypical scrapie in sheep from a UK research flock which is free from classical scrapie.

BMC Vet Res 2009 Feb 10;5. Epub 2009 Feb 10.

Animal Services Unit, Veterinary Laboratories Agency, Woodham Lane, New Haw, Addlestone, Surrey, KT15 3NB, UK.

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http://dx.doi.org/10.1186/1746-6148-5-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649067PMC
February 2009

Prion diseases are efficiently transmitted by blood transfusion in sheep.

Blood 2008 Dec 22;112(12):4739-45. Epub 2008 Jul 22.

Neuropathogenesis Division, Roslin Institute, Compton, United Kingdom.

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http://dx.doi.org/10.1182/blood-2008-04-152520DOI Listing
December 2008

Scrapie: uncertainties, biology and molecular approaches.

Authors:
Nora Hunter

Biochim Biophys Acta 2007 Jun 5;1772(6):619-28. Epub 2007 May 5.

Neuropathogenesis Unit, Roslin Institute, West Mains Road, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1016/j.bbadis.2007.04.007DOI Listing
June 2007

Quantification of Peyer's patches in Cheviot sheep for future scrapie pathogenesis studies.

Vet Immunol Immunopathol 2007 Apr 2;116(3-4):163-71. Epub 2007 Feb 2.

Centre for Infectious Diseases, University of Edinburgh, Ashworth Laboratories, King's Buildings, West Mains Road, Edinburgh EH9 3JF, Scotland, UK.

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http://dx.doi.org/10.1016/j.vetimm.2007.01.017DOI Listing
April 2007

Ovine prion protein variant A(136)R(154)L(168)Q(171) increases resistance to experimental challenge with bovine spongiform encephalopathy agent.

J Gen Virol 2006 Dec;87(Pt 12):3741-5

Institute for Animal Health (IAH), Neuropathogenesis Unit, West Mains Road, Edinburgh EH9 3JF, UK.

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http://dx.doi.org/10.1099/vir.0.82083-0DOI Listing
December 2006

The neuropathologic phenotype of experimental ovine BSE is maintained after blood transfusion.

Blood 2006 Jul 28;108(2):745-8. Epub 2006 Mar 28.

Veterinary Laboratories Agency (VLA-Lasswade), Pentlands Science Park, Bush Loan, Midlothian, UK.

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http://dx.doi.org/10.1182/blood-2005-12-5156DOI Listing
July 2006

Role of lymph-borne cells in the early stages of scrapie agent dissemination from the skin.

Vet Immunol Immunopathol 2006 Feb 16;109(3-4):267-78. Epub 2005 Sep 16.

Division of Veterinary Biomedical Sciences, R(D)SVS, University of Edinburgh, Summerhall, Edinburgh EH9 1QH, UK.

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http://dx.doi.org/10.1016/j.vetimm.2005.08.021DOI Listing
February 2006

Genotype-level variation in lifetime breeding success, litter size and survival of sheep in scrapie-affected flocks.

J Gen Virol 2005 Apr;86(Pt 4):1229-38

Centre for Tropical Veterinary Medicine (CTVM), Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Roslin, Midlothian EH25 9RG, UK.

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http://dx.doi.org/10.1099/vir.0.80277-0DOI Listing
April 2005

Phenotype of disease-associated PrP accumulation in the brain of bovine spongiform encephalopathy experimentally infected sheep.

J Gen Virol 2005 Mar;86(Pt 3):827-38

Veterinary Laboratories Agency (VLA-Lasswade), Pentlands Science Park, Bush Loan, Penicuik, Midlothian EH26 0PZ, UK.

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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.80299-0DOI Listing
March 2005

Immunohistochemical characteristics of disease-associated PrP are not altered by host genotype or route of inoculation following infection of sheep with bovine spongiform encephalopathy.

J Gen Virol 2005 Mar;86(Pt 3):839-48

Veterinary Laboratories Agency (VLA-Lasswade), Pentlands Science Park, Bush Loan, Penicuik, Midlothian EH26 0PZ, UK.

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http://dx.doi.org/10.1099/vir.0.80364-0DOI Listing
March 2005

Architecture of secondary lymphoid tissue in sheep experimentally challenged with scrapie.

Immunology 2004 Feb;111(2):230-6

Centre for Veterinary Science, Department of Clinical Veterinary Medicine, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/j.0019-2805.2003.01789.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782407PMC
February 2004

Scrapie and experimental BSE in sheep.

Authors:
Nora Hunter

Br Med Bull 2003 ;66:171-83

Neuropathogenesis Unit, Institute for Animal Health, Edinburgh, UK.

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http://dx.doi.org/10.1093/bmb/66.1.171DOI Listing
November 2003

Prion diseases: BSE in sheep bred for resistance to infection.

Nature 2003 May;423(6939):498

Institute for Animal Health, Compton, Newbury, Berkshire RG20 7NN, UK.

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http://www.nature.com/articles/423498a
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http://dx.doi.org/10.1038/423498aDOI Listing
May 2003

BSE - a wolf in sheep's clothing?

Trends Microbiol 2002 Dec;10(12):563-70

Institute for Animal Health, Compton Laboratory, Newbury, Berkshire, UK RG20 7NN.

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http://dx.doi.org/10.1016/s0966-842x(02)02477-0DOI Listing
December 2002

Transmission of prion diseases by blood transfusion.

J Gen Virol 2002 Nov;83(Pt 11):2897-905

Institute for Animal Health, Neuropathogenesis Unit, West Mains Road, Edinburgh EH9 3JF, UK.

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http://dx.doi.org/10.1099/0022-1317-83-11-2897DOI Listing
November 2002

Patterns of cytokine gene expression of naïve and memory T lymphocytes in vivo.

Vet Immunol Immunopathol 2002 Sep;87(3-4):261-4

Laboratory for Clinical and Molecular Virology, The University of Edinburgh, Summerhall, Edinburgh EH9 1QH, UK.

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http://dx.doi.org/10.1016/s0165-2427(02)00050-8DOI Listing
September 2002

Laboratory studies of bovine spongiform encephalopathy.

Authors:
Nora Hunter

Lancet 2002 Aug;360(9331):488-9

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http://dx.doi.org/10.1016/S0140-6736(02)09648-4DOI Listing
August 2002