Noor Kalsheker

Noor Kalsheker

UNVERIFIED PROFILE

Are you Noor Kalsheker?   Register this Author

Register author
Noor Kalsheker

Noor Kalsheker

Publications by authors named "Noor Kalsheker"

Are you Noor Kalsheker?   Register this Author

47Publications

857Reads

10Profile Views

Next generation sequencing of CLU, PICALM and CR1: pitfalls and potential solutions.

Int J Mol Epidemiol Genet 2012 15;3(4):262-75. Epub 2012 Nov 15.

Human Genetics, School of Molecular Medical Sciences, Queens Medical Centre, University of Nottingham Nottingham, UK.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508540PMC
December 2012

Cognitive phenotypes in Alzheimer's disease and genetic variants in ACE and IDE.

Neurobiol Aging 2012 Jul 12;33(7):1486.e1-2. Epub 2011 Jan 12.

Cerebral Function Unit, Salford Royal NHS Foundation Trust, Salford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2010.11.003DOI Listing
July 2012

Investigating statistical epistasis in complex disorders.

J Alzheimers Dis 2011 ;25(4):635-44

Human Genetics, School of Molecular Medical Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-2011-110197DOI Listing
November 2011

Matrix metalloproteinase-12 (MMP-12) SNP affects MMP activity, lung macrophage infiltration and protects against emphysema in COPD.

Thorax 2011 Nov 5;66(11):970-6. Epub 2011 Jul 5.

Division of Therapeutics and Molecular Medicine and NIHR Respiratory Biomedical Research Unit, Queens Medical Centre, University of Nottingham, D Floor, South Block, Queen's Medical Centre, Nottingham NG7 2UH, UK.

View Article

Download full-text PDF

Source
http://thorax.bmj.com/cgi/doi/10.1136/thx.2011.159087
Publisher Site
http://dx.doi.org/10.1136/thx.2011.159087DOI Listing
November 2011

Analysis of Genome-Wide Association Study (GWAS) data looking for replicating signals in Alzheimer's disease (AD).

Int J Mol Epidemiol Genet 2010 15;1(1):53-66. Epub 2009 Nov 15.

Division of Clinical Chemistry, Institute of Genetics, School of Molecular Medical Sciences, Queen's Medical Centre, University of Nottingham Nottingham, NG7 2UH, UK.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076755PMC
July 2011

Deletion of Serpina1a, a murine α1-antitrypsin ortholog, results in embryonic lethality.

Exp Lung Res 2011 Jun 16;37(5):291-300. Epub 2011 May 16.

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/01902148.2011.554599DOI Listing
June 2011

Using Fisher's method with PLINK 'LD clumped' output to compare SNP effects across Genome-wide Association Study (GWAS) datasets.

Int J Mol Epidemiol Genet 2011 Jan 25;2(1):30-5. Epub 2010 Nov 25.

Human Genetics, School of Molecular Medical Sciences, Queens Medical Centre, University of Nottingham Nottingham NG7 2UH, UK.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077236PMC
January 2011

A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with alpha1-antitrypsin deficiency.

Hepatology 2010 Sep;52(3):1078-88

Department of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/Medical Research Council Building, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.23760DOI Listing
September 2010

PSEN1 polymorphisms alter the rate of cognitive decline in sporadic Alzheimer's disease patients.

Neurobiol Aging 2009 Dec 9;30(12):1992-9. Epub 2008 Apr 9.

Division of Clinical Chemistry, Institute of Genetics, Queen's Medical Centre, University of Nottingham, NG7 2UH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2008.02.013DOI Listing
December 2009

The alpha-1-antitrypsin gene promoter in human A549 lung derived cells, and a novel transcription initiation site.

Int J Biochem Cell Biol 2009 May 28;41(5):1157-64. Epub 2008 Oct 28.

School of Molecular Medical Sciences, Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham NG7 2UH, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biocel.2008.10.020DOI Listing
May 2009

A study of three candidate genes for pre-eclampsia in a Sinhalese population from Sri Lanka.

J Obstet Gynaecol Res 2009 Apr;35(2):234-42

Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
April 2009

The new genetics and chronic obstructive pulmonary disease.

COPD 2008 Aug;5(4):257-64

Division of Clinical Chemistry, Molecular Medical Sciences Institute of Genetics, Queens Medical Centre, University of Nottingham, Nottingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15412550802237556DOI Listing
August 2008

Alpha1-antitrypsin deficiency: current perspective on research, diagnosis, and management.

Int J Chron Obstruct Pulmon Dis 2006 ;1(2):151-60

Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706616PMC
February 2008

A polymorphism of the alpha1-antitrypsin gene represents a risk factor for liver disease.

Hepatology 2008 Jan;47(1):127-32

Institute of Genetics, University of Nottingham, Nottingham, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.21979DOI Listing
January 2008

Regulatory region single nucleotide polymorphisms of the apolipoprotein E gene and the rate of cognitive decline in Alzheimer's disease.

Hum Mol Genet 2007 Sep 5;16(18):2199-208. Epub 2007 Jul 5.

Division of Clinical Chemistry, Queen's Medical Centre, University of Nottingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddm171DOI Listing
September 2007

SERPINA3 (aka alpha-1-antichymotrypsin).

Front Biosci 2007 May 1;12:2821-35. Epub 2007 May 1.

The University of Nottingham, Division of Clinical Chemistry, Molecular Medical Sciences, Institute of Genetics, University Hospital, Queen's Medical Centre, Nottingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2741/2275DOI Listing
May 2007

The hydroxy-methyl-glutaryl CoA reductase promoter polymorphism is associated with Alzheimer's risk and cognitive deterioration.

Neurosci Lett 2007 Apr 25;416(1):66-70. Epub 2007 Jan 25.

Department of Experimental Pathology, School of Medicine University of Bologna, Via San Giacomo 14, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neulet.2007.01.046DOI Listing
April 2007

Effects of Alzheimer's peptide and alpha1-antichymotrypsin on astrocyte gene expression.

Neurobiol Aging 2007 Jan 20;28(1):51-61. Epub 2005 Dec 20.

Institute of Genetics, School of Molecular Medical Sciences, University of Nottingham, Nottingham NG7 2UH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2005.10.017DOI Listing
January 2007

Altered transmission of maternal angiotensin II receptor haplotypes in fetal growth restriction.

Hum Mutat 2006 Feb;27(2):138-44

Division of Clinical Chemistry, Institute of Genetics, School of Molecular Medical Sciences, University Hospital, Nottingham, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.20265DOI Listing
February 2006

Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease.

Hum Mutat 2006 Jan;27(1):103-9

Division of Clinical Chemistry, Molecular Medical Sciences, Institute of Genetics, University Hospital, Queens Medical Centre, University of Nottingham, Nottingham, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.20275DOI Listing
January 2006

A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer's disease.

Neurobiol Aging 2005 Apr;26(4):449-53

Department of Experimental Pathology, School of Medicine, University of Bologna, Via S. Giacomo 14, 40126 Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2004.05.001DOI Listing
April 2005

Haplotypes of the alpha-1 antitrypsin gene in healthy controls and Z deficiency patients.

Hum Mutat 2004 Dec;24(6):535-6

Division of Clinical Chemistry, Institute of Genetics, University of Nottingham, Nottingham, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.9294DOI Listing
December 2004

Allele-specific overexpression in astrocytes of an Alzheimer's disease associated alpha-1-antichymotrypsin promoter polymorphism.

Brain Res Mol Brain Res 2004 Nov;131(1-2):88-92

Division of Clinical Chemistry, Institute of Genetics, Queens' Medical Centre, University of Nottingham, Nottingham, NG7 2UH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molbrainres.2004.08.012DOI Listing
November 2004

Haplotypes of the angiotensin II receptor genes AGTR1 and AGTR2 in women with normotensive pregnancy and women with preeclampsia.

Hum Mutat 2004 Jul;24(1):14-20

Clinical Chemistry, Institute of Genetics, School of Molecular Medical Sciences, University of Nottingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.20050DOI Listing
July 2004

Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer's disease.

Int J Biochem Cell Biol 2003 Nov;35(11):1505-35

Division of Clinical Chemistry, Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK.

View Article

Download full-text PDF

Source
November 2003

Serpins: structure, function and molecular evolution.

Int J Biochem Cell Biol 2003 Nov;35(11):1536-47

Division of Clinical Chemistry, Institute of Genetics, Queen's Medical Centre, University of Nottingham, NG7 2UH Nottingham, UK.

View Article

Download full-text PDF

Source
November 2003

House dust mite Der p 1 downregulates defenses of the lung by inactivating elastase inhibitors.

Am J Respir Cell Mol Biol 2003 Sep 10;29(3 Pt 1):381-9. Epub 2003 Apr 10.

School of Pharmaceutical Sciences, University of Nottingham, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1165/rcmb.2003-0060OCDOI Listing
September 2003

Oncostatin M induced alpha1-antitrypsin (AAT) gene expression in Hep G2 cells is mediated by a 3' enhancer.

Biochem J 2002 Jul;365(Pt 2):555-60

Division of Clinical Chemistry, School of Clinical Laboratory Sciences, Queen's Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BJ20011312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1222683PMC
July 2002

Gene regulation of the serine proteinase inhibitors alpha1-antitrypsin and alpha1-antichymotrypsin.

Biochem Soc Trans 2002 Apr;30(2):93-8

Division of Clinical Chemistry, School of Clinical Laboratory Sciences, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH, U.K.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/DOI Listing
April 2002