Noemi Cowan

Noemi Cowan

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Noemi Cowan

Noemi Cowan

Publications by authors named "Noemi Cowan"

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Exposure of Heligmosomoides polygyrus and Trichuris muris to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate in vitro and in vivo to elucidate the pathway of drug entry into these gastrointestinal nematodes.

Int J Parasitol Drugs Drug Resist 2017 08 24;7(2):159-173. Epub 2017 Mar 24.

Department of Medical Parasitology and Infection Biology Swiss Tropical and Public Health Institute, P.O. Box, CH-4002 Basel, Switzerland; University of Basel, P.O. Box, CH-4003 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ijpddr.2017.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377441PMC
August 2017

Approved oncology drugs lack in vivo activity against Trichuris muris despite in vitro activity.

Parasitol Res 2016 Nov 8;115(11):4443-4446. Epub 2016 Aug 8.

Swiss Tropical and Public Health Institute, P.O. Box CH-4002, Basel, Switzerland.

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http://dx.doi.org/10.1007/s00436-016-5225-9DOI Listing
November 2016

In Vitro and In Vivo Drug Interaction Study of Two Lead Combinations, Oxantel Pamoate plus Albendazole and Albendazole plus Mebendazole, for the Treatment of Soil-Transmitted Helminthiasis.

Antimicrob Agents Chemother 2016 10 23;60(10):6127-33. Epub 2016 Sep 23.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland

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http://dx.doi.org/10.1128/AAC.01217-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038309PMC
October 2016

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

Bimodal X-ray and Infrared Imaging of an Organometallic Derivative of Praziquantel in Schistosoma mansoni.

Chembiochem 2016 06 28;17(11):1004-7. Epub 2016 Apr 28.

École Normale Supérieure, PSL Research University, Département de Chimie, 24 rue Lhomond, 75005, Paris, France.

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http://dx.doi.org/10.1002/cbic.201500688DOI Listing
June 2016

Elucidation of the in vitro and in vivo activities of bridged 1,2,4-trioxolanes, bridged 1,2,4,5-tetraoxanes, tricyclic monoperoxides, silyl peroxides, and hydroxylamine derivatives against Schistosoma mansoni.

Bioorg Med Chem 2015 Aug 14;23(16):5175-81. Epub 2015 Feb 14.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, PO Box, CH-4002 Basel, Switzerland; University of Basel, PO Box, CH-4003 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2015.02.010DOI Listing
August 2015

Repurposing of anticancer drugs: in vitro and in vivo activities against Schistosoma mansoni.

Parasit Vectors 2015 Aug 13;8:417. Epub 2015 Aug 13.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, P.O. Box, CH-4002, Basel, Switzerland.

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http://dx.doi.org/10.1186/s13071-015-1023-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533769PMC
August 2015

Activities of N,N'-Diarylurea MMV665852 analogs against Schistosoma mansoni.

Antimicrob Agents Chemother 2015 Apr 12;59(4):1935-41. Epub 2015 Jan 12.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland

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http://dx.doi.org/10.1128/AAC.04463-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356791PMC
April 2015

Orally active antischistosomal early leads identified from the open access malaria box.

PLoS Negl Trop Dis 2014 9;8(1):e2610. Epub 2014 Jan 9.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland ; University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1371/journal.pntd.0002610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886923PMC
September 2014

Activity of praziquantel enantiomers and main metabolites against Schistosoma mansoni.

Antimicrob Agents Chemother 2014 Sep 30;58(9):5466-72. Epub 2014 Jun 30.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland

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http://dx.doi.org/10.1128/AAC.02741-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135865PMC
September 2014