Noelle Frey

Noelle Frey

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Noelle Frey

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Chimeric antigen receptor T cells for acute lymphoblastic leukemia.

Authors:
Noelle V Frey

Am J Hematol 2019 May 22;94(S1):S24-S27. Epub 2019 Mar 22.

Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/ajh.25442DOI Listing
May 2019

Cytokine Release Syndrome with Chimeric Antigen Receptor T Cell Therapy.

Biol Blood Marrow Transplant 2019 04 23;25(4):e123-e127. Epub 2018 Dec 23.

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1016/j.bbmt.2018.12.756DOI Listing
April 2019

Tocilizumab for the treatment of severe steroid-refractory acute graft-versus-host disease of the lower gastrointestinal tract.

Bone Marrow Transplant 2019 02 24;54(2):212-217. Epub 2018 May 24.

Blood and Marrow Transplantation Program, Abramson Cancer Center and the Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

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http://www.nature.com/articles/s41409-018-0236-z
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http://dx.doi.org/10.1038/s41409-018-0236-zDOI Listing
February 2019

Early positron emission tomography/computed tomography as a predictor of response after CTL019 chimeric antigen receptor -T-cell therapy in B-cell non-Hodgkin lymphomas.

Cytotherapy 2018 12 29;20(12):1415-1418. Epub 2018 Oct 29.

Lymphoma Program at the Abramson Cancer Center and the Division of Hematology-Oncology Perelman School of Medicine, University of Pennsylvania, Pennsylvania, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S14653249183063
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http://dx.doi.org/10.1016/j.jcyt.2018.10.003DOI Listing
December 2018

Higher Donor Apheresis Blood Volumes Are Associated with Reduced Relapse Risk and Improved Survival in Reduced-Intensity Allogeneic Transplantations with Unrelated Donors.

Biol Blood Marrow Transplant 2018 06 2;24(6):1203-1208. Epub 2018 Feb 2.

Blood and Marrow Transplantation Program and Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2018.01.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993582PMC
June 2018

Grading of cytokine release syndrome associated with the CAR T cell therapy tisagenlecleucel.

J Hematol Oncol 2018 03 2;11(1):35. Epub 2018 Mar 2.

Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1186/s13045-018-0571-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833070PMC
March 2018

Cytokine release syndrome: Who is at risk and how to treat.

Authors:
Noelle Frey

Best Pract Res Clin Haematol 2017 12 22;30(4):336-340. Epub 2017 Sep 22.

Blood and Marrow Transplantation, University of Pennsylvania Medical Center, United States. Electronic address:

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http://dx.doi.org/10.1016/j.beha.2017.09.002DOI Listing
December 2017

The what, when and how of CAR T cell therapy for ALL.

Authors:
Noelle Frey

Best Pract Res Clin Haematol 2017 09 3;30(3):275-281. Epub 2017 Aug 3.

Hospital of the University of Pennsylvania Philadelphia, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.beha.2017.07.009DOI Listing
September 2017

The promise of chimeric antigen receptor T cells (CARTs) in leukaemia.

Br J Haematol 2017 04 15;177(1):13-26. Epub 2016 Dec 15.

Department of Hematology-Oncology, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/bjh.14475DOI Listing
April 2017

Cytokine Release Syndrome After Chimeric Antigen Receptor T Cell Therapy for Acute Lymphoblastic Leukemia.

Crit Care Med 2017 Feb;45(2):e124-e131

1Division of Critical Care Medicine, Department of Anesthesia and Critical Care, The Children's Hospital of Philadelphia and The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 2Division of Oncology, Department of Pediatrics, The Children's Hospital of Philadelphia and The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 3Center for Cellular Immunotherapies, Department of Pathology and Laboratory Medicine, The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 4Department of Biostatistics and Epidemiology, The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 5Division of Hematology-Oncology, Department of Medicine, Abramson Cancer Center, The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1097/CCM.0000000000002053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452983PMC
February 2017

Cytokine release syndrome with novel therapeutics for acute lymphoblastic leukemia.

Hematology Am Soc Hematol Educ Program 2016 Dec;2016(1):567-572

Abramson Cancer Center, Hospital of the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1182/asheducation-2016.1.567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142489PMC
December 2016

Evaluating the skin in patients undergoing chimeric antigen receptor modified T-cell therapy.

J Am Acad Dermatol 2016 Nov;75(5):1054-1057

Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2016.06.062DOI Listing
November 2016

The cytological features of CAR(T) cells.

Br J Haematol 2016 11 9;175(3):366. Epub 2016 Sep 9.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, University of Pennsylvania, Philadelphia, PA, 19104.

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http://dx.doi.org/10.1111/bjh.14286DOI Listing
November 2016

The Promise of Chimeric Antigen Receptor T-Cell Therapy.

Oncology (Williston Park) 2016 10;30(10):880-8, 890

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October 2016

Nelarabine, cyclosphosphamide and etoposide for adults with relapsed T-cell acute lymphoblastic leukaemia and lymphoma.

Br J Haematol 2016 07 25;174(2):332-4. Epub 2015 Sep 25.

Abramson Cancer Center and the Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/bjh.13771DOI Listing
July 2016

Autologous stem cell transplantation in first complete remission may not extend progression-free survival in patients with peripheral T cell lymphomas.

Am J Hematol 2016 07 24;91(7):672-6. Epub 2016 Apr 24.

Abramson Cancer Center and the Division of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/ajh.24372DOI Listing
July 2016

Measuring IL-6 and sIL-6R in serum from patients treated with tocilizumab and/or siltuximab following CAR T cell therapy.

J Immunol Methods 2016 07 3;434:1-8. Epub 2016 Apr 3.

University of Pennsylvania, Department of Pathology and Laboratory Medicine, Product Development & Correlative Sciences Laboratory, Abramson Cancer Center of the University of Pennsylvania, Philadelphia, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jim.2016.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490247PMC
July 2016

Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia.

Cancer Discov 2016 06 13;6(6):664-79. Epub 2016 Apr 13.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Department of Pediatrics, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. Abramson Cancer Center, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. Department of Pathology and Laboratory Medicine, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/2159-8290.CD-16-0040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448406PMC
June 2016

CAR T Cell Therapy in Acute Lymphoblastic Leukemia and Potential for Chronic Lymphocytic Leukemia.

Curr Treat Options Oncol 2016 06;17(6):28

Division of Oncology, The Children's Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, 3012 CTRB, 3501 Civic Center Blvd., Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s11864-016-0406-4DOI Listing
June 2016

CAR T-cells merge into the fast lane of cancer care.

Am J Hematol 2016 Jan;91(1):146-50

Division of Hematology Oncology, University of Pennsylvania, 3400 Civic Center Boulevard, PCAM 2 West Pavilion, Philadelphia, Pennsylvania, 19104.

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http://dx.doi.org/10.1002/ajh.24238DOI Listing
January 2016

Implementation of an Advanced Practice Provider Service on an Allogeneic Stem Cell Transplant Unit: Impact on Patient Outcomes.

Biol Blood Marrow Transplant 2015 Sep 29;21(9):1692-8. Epub 2015 May 29.

Division of General Internal Medicine, University of Pennsylvania and Center for Health Equity Research and Promotion, Philadelphia VA Medical Center, Division of General Internal Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1016/j.bbmt.2015.05.021DOI Listing
September 2015

Outpatient Autologous Stem Cell Transplantation for Patients With Myeloma.

Clin Lymphoma Myeloma Leuk 2015 Sep 6;15(9):536-40. Epub 2015 Jun 6.

Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2015.05.006DOI Listing
September 2015

Erythrodermic Leukemia Cutis in a Patient With Pre-B-Cell Acute Lymphoblastic Leukemia.

Am J Dermatopathol 2015 Aug;37(8):650-2

*Stanford Dermatopathology Service, Department of Pathology, Stanford Medical Center, Stanford, CA; †Department of Dermatology, University of Iowa, Iowa City, IA; ‡Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA; §Division of Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA; and ¶Department of Pathology, Hospital of the University of Pennsylvania, Philadelphia, PA.

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http://pdfs.journals.lww.com/amjdermatopathology/2015/08000/
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/DAD.0000000000000240DOI Listing
August 2015

How I treat adults with relapsed or refractory Philadelphia chromosome-negative acute lymphoblastic leukemia.

Blood 2015 Jul 12;126(5):589-96. Epub 2015 May 12.

Hematology-Oncology Division, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-09-55
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http://dx.doi.org/10.1182/blood-2014-09-551937DOI Listing
July 2015

Voriconazole-induced periostitis after allogeneic stem cell transplantation.

Am J Hematol 2015 Jun 29;90(6):574-5. Epub 2015 Apr 29.

Division of Hematology Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/ajh.23977DOI Listing
June 2015

Early donor chimerism levels predict relapse and survival after allogeneic stem cell transplantation with reduced-intensity conditioning.

Biol Blood Marrow Transplant 2014 Nov 10;20(11):1758-66. Epub 2014 Jul 10.

Abramson Cancer Center and the Division of Hematology & Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1016/j.bbmt.2014.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194246PMC
November 2014

Chimeric antigen receptor T cells for sustained remissions in leukemia.

N Engl J Med 2014 Oct;371(16):1507-17

From the Division of Oncology, Children's Hospital of Philadelphia (S.L.M., R.A., D.M.B., N.J.B., S.R.R., D.T.T., S.A.G.), the Departments of Pediatrics (S.L.M., R.A., D.M.B., N.J.B., S.R.R., D.T.T., S.A.G.), Biostatistics and Epidemiology (P.A.S., R.A.), and Pathology and Laboratory Medicine (J.J.M., B.L.L., C.H.J., S.A.G.), the Division of Hematology-Oncology (N.F., D.L.P.), and Abramson Cancer Center (N.F., A.C., V.E.G., Z.Z., S.F.L., Y.D.M., J.J.M., B.L.L., C.H.J., D.L.P., S.A.G.), Perelman School of Medicine, University of Pennsylvania - all in Philadelphia; and Novartis Pharmaceuticals, East Hanover, NJ (A.S.).

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http://dx.doi.org/10.1056/NEJMoa1407222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267531PMC
October 2014

Eltrombopag-associated hyperpigmentation.

JAMA Dermatol 2013 Sep;149(9):1112-5

Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1001/jamadermatol.2013.5107DOI Listing
September 2013

Eltrombopag and serum of a different hue.

Arch Pathol Lab Med 2013 Sep;137(9):1175

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http://dx.doi.org/10.5858/arpa.2012-0716-LEDOI Listing
September 2013

Receipt of maintenance therapy is most predictive of survival in older acute lymphoblastic leukemia patients treated with intensive induction chemotherapy regimens.

Am J Hematol 2013 Aug 5;88(8):657-60. Epub 2013 Jun 5.

Division of Hematology/Oncology, Abramson Cancer Center, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1002/ajh.23468DOI Listing
August 2013

Characteristics and outcome of acute myeloid leukemia in patients with a prior history of autoimmune disease.

Leuk Lymphoma 2013 Jun 19;54(6):1235-41. Epub 2013 Feb 19.

Abramson Cancer Center, Division of Hematology/Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.3109/10428194.2012.736982DOI Listing
June 2013

Spontaneous subcapsular splenic hematoma associated with filgrastim in a patient undergoing allogeneic hematopoietic stem cell transplantation.

Ann Pharmacother 2013 May 12;47(5):e22. Epub 2013 Apr 12.

Pharmacy Department, Hospital of University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1345/aph.1S005DOI Listing
May 2013

Functional unresponsiveness and replicative senescence of myeloid leukemia antigen-specific CD8+ T cells after allogeneic stem cell transplantation.

Clin Cancer Res 2009 Aug 14;15(15):4944-53. Epub 2009 Jul 14.

Abramson Family Cancer Research Institute, Abramson Cancer Center, Department of Pathology and Laboratory Medicine, Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-3332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722844PMC
August 2009

Graft-versus-host disease after donor leukocyte infusions: presentation and management.

Best Pract Res Clin Haematol 2008 Jun;21(2):205-22

Division of Hematology-Oncology and Abramson Cancer Center, University of Pennsylvania Medical Center, 16 Penn Tower, 3400 ISpruce St, Philadelphia PA 19106, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S152169260800008
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504712PMC
http://dx.doi.org/10.1016/j.beha.2008.02.007DOI Listing
June 2008

The management of posttransplant lymphoproliferative disorder.

Med Oncol 2007 ;24(2):125-36

University of Pennsylvania Cancer Center, 16 Penn Tower, 3400 Spruce Street, Philadelphia, PA 19104, USA.

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December 2007

Primary lymphomas of the cervix and uterus: the University of Pennsylvania's experience and a review of the literature.

Leuk Lymphoma 2006 Sep;47(9):1894-901

Abramson Cancer Center of the Hospital of the University of Pennsylvania, 3400 Spruce, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1080/10428190600687653DOI Listing
September 2006