Publications by authors named "Noel Chan"

91Publications

Direct oral anticoagulants: evidence and unresolved issues.

Lancet 2020 Nov;396(10264):1767-1776

Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada; Population Health Research Institute, Hamilton, ON, Canada; Hamilton General Hospital and McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1016/S0140-6736(20)32439-9DOI Listing
November 2020

Current Challenges in Diagnosis of Venous Thromboembolism.

J Clin Med 2020 Oct 29;9(11). Epub 2020 Oct 29.

Thrombosis and Atherosclerosis Research Institute, Hamilton, ON L8L 2X2, Canada.

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http://dx.doi.org/10.3390/jcm9113509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693569PMC
October 2020

Peripheral Oxygen Saturation in Older Persons Wearing Nonmedical Face Masks in Community Settings.

JAMA 2020 Oct 30. Epub 2020 Oct 30.

Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1001/jama.2020.21905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600049PMC
October 2020

Comparison of Peripapillary Vessel Density of Acute Nonarteritic Anterior Ischemic Optic Neuropathy and Other Optic Neuropathies With Disc Swelling Using Optical Coherence Tomography Angiography: A Pilot Study.

J Neuroophthalmol 2020 Oct 26. Epub 2020 Oct 26.

Hong Kong Eye Hospital (JCC, JKHL, CKMC), Hong Kong, China; Department of Ophthalmology and Visual Sciences (JCC, NCYC, CYC, JKHL, CKMC), the Chinese University of Hong Kong, Hong Kong, China; and Department of Ophthalmology and Visual Sciences (NCYC), the Prince of Wales Hospital and Alice Ho Miu Ling Nethersole Hospital, Hong Kong, China.

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http://dx.doi.org/10.1097/WNO.0000000000001106DOI Listing
October 2020

Recent advances in understanding, diagnosing and treating venous thrombosis.

F1000Res 2020 6;9. Epub 2020 Oct 6.

Thrombosis and Atherosclerosis Research Institute and McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.12688/f1000research.27115.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539078PMC
October 2020

Prevention of Venous Thromboembolism in 2020 and Beyond.

J Clin Med 2020 Aug 1;9(8). Epub 2020 Aug 1.

Division of Hematology and Thromboembolism, Department of Medicine, McMaster University, Hamilton, ON L8N 3Z5, Canada.

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http://dx.doi.org/10.3390/jcm9082467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465935PMC
August 2020

Rivaroxaban for the prevention of major adverse cardiovascular events in patients with coronary or peripheral artery disease.

Future Cardiol 2020 Jul 7. Epub 2020 Jul 7.

Population Health Research Institute, Hamilton, ON, L8L 2X2, Canada.

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http://dx.doi.org/10.2217/fca-2020-0068DOI Listing
July 2020

Efficacy and safety of selective laser trabeculoplasty and pattern scanning laser trabeculoplasty: a randomised clinical trial.

Br J Ophthalmol 2020 Jun 30. Epub 2020 Jun 30.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong

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http://dx.doi.org/10.1136/bjophthalmol-2020-316178DOI Listing
June 2020

A National Canadian Survey of Antithrombotic Therapy After Urgent and Emergent Limb Revascularization.

Can J Cardiol 2020 Jun 22. Epub 2020 Jun 22.

Population Health Research Institute, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.cjca.2020.06.008DOI Listing
June 2020

Refining Risk Prediction for Recurrent Venous Thromboembolism: Can We Do Better?

Authors:
Ke Xu Noel C Chan

Thromb Haemost 2020 05 5;120(5):725-727. Epub 2020 May 5.

Thrombosis and Atherosclerosis Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1055/s-0040-1709686DOI Listing
May 2020

Optimal Prescription of the Lower Dose of Apixaban.

J Am Coll Cardiol 2020 03;75(10):1156-1158

Population Health Research Institute and Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada; McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jacc.2019.12.061DOI Listing
March 2020

The conundrum of resuming anticoagulant therapy after intracerebral bleeding: In whom, when, and how?

Authors:
Ke Xu Noel C Chan

Vasc Med 2020 02 13;25(1):60-62. Epub 2020 Jan 13.

Department of Medicine, Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1177/1358863X19897140DOI Listing
February 2020

Novel antithrombotic strategies for treatment of venous thromboembolism.

Blood 2020 01;135(5):351-359

Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada; and Department of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1182/blood.2019000919DOI Listing
January 2020

Atypical presentations of intracranial dysgerminoma mimicking central nervous system inflammatory or demyelinating disease.

Can J Ophthalmol 2020 04 13;55(2):159-166. Epub 2019 Sep 13.

Department of Pathology, Houston Methodist Hospital, Houston, TX.

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http://dx.doi.org/10.1016/j.jcjo.2019.07.018DOI Listing
April 2020

Fifty years of research on antithrombotic therapy: Achievements and disappointments.

Eur J Intern Med 2019 Dec 1;70:1-7. Epub 2019 Nov 1.

Department of Medicine, McMaster University, Hamilton, Ontario, Canada; Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada; Population Health Research Institute, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ejim.2019.10.023DOI Listing
December 2019

Bleeding in patients with atrial fibrillation treated with combined antiplatelet and anticoagulant therapy: time to turn the corner.

Authors:
Ke Xu Noel C Chan

Ann Transl Med 2019 Sep;7(Suppl 6):S198

Thrombosis and Atherosclerosis Research Institute, Department of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.21037/atm.2019.07.40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789336PMC
September 2019

Are Ticks the Answer to Medical Device-Associated Clotting?

J Am Coll Cardiol 2019 10;74(17):2190-2192

Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jacc.2019.08.1027DOI Listing
October 2019

Intraocular pressure control and visual field changes in primary angle closure disease: the CUHK PACG Longitudinal (CUPAL) study.

Br J Ophthalmol 2020 05 7;104(5):629-635. Epub 2019 Aug 7.

Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong Faculty of Medicine, Hong Kong, China

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http://dx.doi.org/10.1136/bjophthalmol-2019-314322DOI Listing
May 2020

Response by Chan and Weitz to Letter Regarding Article, "Antithrombotic Agents: New Directions in Antithrombotic Therapy".

Circ Res 2019 06 6;124(12):e119. Epub 2019 Jun 6.

Thrombosis and Atherosclerosis Research Institute and Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1161/CIRCRESAHA.119.315235DOI Listing
June 2019

How I manage anticoagulant therapy in older individuals with atrial fibrillation or venous thromboembolism.

Blood 2019 05 29;133(21):2269-2278. Epub 2019 Mar 29.

Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada; Population Health Research Institute, Hamilton, ON, Canada; and Department of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1182/blood-2019-01-846048DOI Listing
May 2019

MAA868 locks factor XIa in a zymogen-like state.

Blood 2019 03;133(13):1393-1394

Thrombosis and Atherosclerosis Research Institute.

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http://dx.doi.org/10.1182/blood-2019-02-900480DOI Listing
March 2019

AB023, A Novel Antibody That Binds Factor XI and Blocks Its Activation by Factor XIIa.

Arterioscler Thromb Vasc Biol 2019 04;39(4):533-535

From the Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada; and Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1161/ATVBAHA.119.312459DOI Listing
April 2019

Long-Term Management of Venous Thromboembolism: Lessons from EINSTEIN CHOICE and Other Extension Trials.

Thromb Haemost 2019 May 26;119(5):689-694. Epub 2019 Feb 26.

Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1055/s-0039-1679906DOI Listing
May 2019

Rivaroxaban for prevention and treatment of venous thromboembolism.

Future Cardiol 2019 03 19;15(2):63-77. Epub 2019 Feb 19.

Thrombosis & Atherosclerosis Research Institute, McMaster University, Hamilton, Ontario, Canada.

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https://www.futuremedicine.com/doi/10.2217/fca-2018-0076
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http://dx.doi.org/10.2217/fca-2018-0076DOI Listing
March 2019

Antithrombotic Agents.

Circ Res 2019 02;124(3):426-436

From the Thrombosis and Atherosclerosis Research Institute and Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.313155DOI Listing
February 2019

Reduction in Mortality following Elective Major Hip and Knee Surgery: A Systematic Review and Meta-Analysis.

Thromb Haemost 2019 Apr 30;119(4):668-674. Epub 2019 Jan 30.

Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1055/s-0039-1677732DOI Listing
April 2019

The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V-Special Situations.

Thromb Haemost 2019 Jan 31;119(1):14-38. Epub 2018 Dec 31.

Thrombosis and Atherosclerosis Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1055/s-0038-1675816DOI Listing
January 2019

Advances in Antithrombotic Therapy.

Arterioscler Thromb Vasc Biol 2019 01;39(1):7-12

From the Thrombosis and Atherosclerosis Research Institute and Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1161/ATVBAHA.118.310960DOI Listing
January 2019

Utility of a Nurse-Led Pathway for Patients with Acute Venous Thromboembolism Discharged on Rivaroxaban: A Prospective Cohort Study.

Semin Thromb Hemost 2019 Mar 19;45(2):187-195. Epub 2018 Dec 19.

Department of Hematology, Monash Medical Centre, Monash Health, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1055/s-0038-1676320DOI Listing
March 2019

Peak plasma concentration of direct oral anticoagulants in obese patients weighing over 120 kilograms: A retrospective study.

Res Pract Thromb Haemost 2018 Oct 29;2(4):684-688. Epub 2018 Aug 29.

Division of Hematology and Thromboembolism Department of Medicine Thrombosis and Atherosclerosis Research Institute McMaster University Hamilton ON Canada.

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http://doi.wiley.com/10.1002/rth2.12146
Publisher Site
http://dx.doi.org/10.1002/rth2.12146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178753PMC
October 2018

In Vitro Reversal of the Anti-Aggregant Effect of Ticagrelor Using Untreated Platelets.

Thromb Haemost 2018 Nov 17;118(11):1895-1901. Epub 2018 Oct 17.

Population Health Research Institute, Hamilton, Ontario, Canada.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1673381
Publisher Site
http://dx.doi.org/10.1055/s-0038-1673381DOI Listing
November 2018

Antiplatelet therapy in the management of atherothrombosis: recent clinical advances.

Blood Adv 2018 07;2(14):1806

Department of Medicine and Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1182/bloodadvances.2018005074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058229PMC
July 2018

The Role of Optical Coherence Tomography in the Acute Management of Neuro-Ophthalmic Diseases.

Asia Pac J Ophthalmol (Phila) 2018 Jul-Aug;7(4):265-270. Epub 2018 Jun 25.

Hong Kong Eye Hospital, Hong Kong.

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http://dx.doi.org/10.22608/APO.2018181DOI Listing
August 2018

Quantifying immature platelets as markers of increased platelet production after coronary artery bypass grafting surgery.

Eur J Haematol 2018 Sep 27;101(3):362-367. Epub 2018 Jul 27.

Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1111/ejh.13109DOI Listing
September 2018

Development of a Dynamic Multi-Protein Signature of Postoperative Delirium.

J Gerontol A Biol Sci Med Sci 2019 01;74(2):261-268

Division of General Medicine and Primary Care, Department of Medicine, Beth Israel Deaconess Medical Center (BIDMC), Boston, Massachusetts.

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http://dx.doi.org/10.1093/gerona/gly036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333936PMC
January 2019

Incidence and risk factors for acute kidney injury in patients with excessive anticoagulation on warfarin: a retrospective study.

J Thromb Thrombolysis 2018 May;45(4):557-561

Division of Hematology and Thromboembolism, Department of Medicine, and Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, Canada.

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http://dx.doi.org/10.1007/s11239-018-1626-1DOI Listing
May 2018

The value of novel oral anticoagulants in rural Australia.

Med J Aust 2018 01;208(1):15-16

Population Health Research Institute, Hamilton, ON, Canada.

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http://dx.doi.org/10.5694/mja17.00592DOI Listing
January 2018

Measuring Dabigatran Levels: What Tests Are Available and What Still Needs to Be Done?

Thromb Haemost 2017 12 6;117(12):2213-2214. Epub 2017 Dec 6.

Thrombosis and Atherosclerosis Research Institute, Hamilton, Canada.

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http://dx.doi.org/10.1160/TH17-10-0705DOI Listing
December 2017

The impact of immigration on the breastfeeding practices of Mainland Chinese immigrants in Hong Kong.

Birth 2018 03 28;45(1):94-102. Epub 2017 Sep 28.

School of Nursing, The University of British Columbia, Okanagan Campus, Canada.

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http://dx.doi.org/10.1111/birt.12314DOI Listing
March 2018

Immune thrombocytopenic purpura associated with fingolimod.

BMJ Case Rep 2017 Sep 11;2017. Epub 2017 Sep 11.

Department of Clinical Haematology, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1136/bcr-2017-220590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623287PMC
September 2017

The use of optical coherence tomography in neuro-ophthalmology.

Curr Opin Ophthalmol 2017 Nov;28(6):552-557

aHong Kong Eye Hospital bDepartment of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1097/ICU.0000000000000418DOI Listing
November 2017

Platelet Transfusion for Ticagrelor Reversal.

Circ Cardiovasc Interv 2017 08;10(8)

From the Population Health Research Institute (P.K., J.W.E.); Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada (N.C., J.W.E.); and Hamilton Health Science Corporation and McMaster University, Ontario, Canada (P.K., N.C., J.W.E.).

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.005579DOI Listing
August 2017

Anticoagulation for Mechanical Heart Valves: Will Oral Factor Xa Inhibitors Be Effective?

Arterioscler Thromb Vasc Biol 2017 05;37(5):743-745

From the Thrombosis and Atherosclerosis Research Institute, David Braley Research Institute, Hamilton, Canada (N.C.C., J.I.W., J.W.E.); and Department of Medicine, McMaster University, Hamilton, Canada (N.C.C., J.I.W., J.W.E.).

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http://dx.doi.org/10.1161/ATVBAHA.117.309223DOI Listing
May 2017

Optic Disc and Macular Imaging in Blind Eyes from Non-glaucomatous Optic Neuropathy: A Study with Spectral-domain Optical Coherence Tomography.

Neuroophthalmology 2017 Feb 31;41(1):1-6. Epub 2016 Oct 31.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong; Hong Kong Eye Hospital, Kowloon, Hong Kong.

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http://dx.doi.org/10.1080/01658107.2016.1238487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278782PMC
February 2017

Rivaroxaban in treatment refractory heparin-induced thrombocytopenia.

BMJ Case Rep 2016 Aug 12;2016. Epub 2016 Aug 12.

Department of Haematology, Monash Health, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1136/bcr-2016-216110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986039PMC
August 2016

Evolving Treatments for Arterial and Venous Thrombosis: Role of the Direct Oral Anticoagulants.

Circ Res 2016 Apr;118(9):1409-24

From the Population Health Research Institute (N.C.C., J.W.E.) and Department of Medicine (J.W.E., J.I.W.), McMaster University, Hamilton, Ontario, Canada; Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada (J.W.E., J.I.W.); and Department of Medicine, Monash University, Clayton, Victoria, Australia (N.C.C.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.306925DOI Listing
April 2016

Antiplatelet therapy: Net benefit of ticagrelor in patients with chronic kidney disease.

Nat Rev Nephrol 2016 Jan 7;12(1):10-1. Epub 2015 Dec 7.

Population Health Research Institute, 237 Barton Street East, Hamilton, Ontario L8L 2X2, Canada.

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http://dx.doi.org/10.1038/nrneph.2015.196DOI Listing
January 2016

Laboratory measurement of the direct oral anticoagulants.

Br J Haematol 2016 Feb 22;172(3):315-36. Epub 2015 Oct 22.

Population Health Research Institute, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1111/bjh.13810DOI Listing
February 2016

Evaluating coagulation tests in patients with atrial fibrillation using direct oral anticoagulants.

Expert Rev Cardiovasc Ther 2015 Nov 15;13(11):1213-23. Epub 2015 Oct 15.

b 2 Population Health Research Institute, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1586/14779072.2015.1096779DOI Listing
November 2015

Associations of pubertal stage and body mass index with cardiometabolic risk in Hong Kong Chinese children: A cross-sectional study.

BMC Pediatr 2015 Sep 24;15:136. Epub 2015 Sep 24.

Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1186/s12887-015-0446-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582725PMC
September 2015

Dabigatran is Less Effective Than Warfarin at Attenuating Mechanical Heart Valve-Induced Thrombin Generation.

J Am Heart Assoc 2015 Aug 24;4(8):e002322. Epub 2015 Aug 24.

Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, Ontario, Canada (I.H.J., A.R.S., J.C.F., J.I.W.) Department of Medical Sciences, McMaster University, Hamilton, Ontario, Canada (I.H.J., J.I.W.) Department of Medicine, McMaster University, Hamilton, Ontario, Canada (A.R.S., J.C.F., J.I.W.) Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada (J.I.W.).

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http://dx.doi.org/10.1161/JAHA.115.002322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599481PMC
August 2015

Effect on Baby-Friendly Hospital Steps When Hospitals Implement a Policy to Pay for Infant Formula.

J Hum Lact 2016 May 18;32(2):238-49. Epub 2015 Aug 18.

College of Nursing and Healthcare Innovation, Arizona State University, AZ, USA.

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http://dx.doi.org/10.1177/0890334415599399DOI Listing
May 2016

Platelet function testing: does a randomized controlled trial settle the debate?

J Neurointerv Surg 2016 Aug 23;8(8):768-9. Epub 2015 Jul 23.

NeuroEndovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/neurintsurg-2015-011954DOI Listing
August 2016

Profile of betrixaban and its potential in the prevention and treatment of venous thromboembolism.

Vasc Health Risk Manag 2015 26;11:343-51. Epub 2015 Jun 26.

Population Health Research Institute, Hamilton, ON, Canada ; Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada ; Department of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.2147/VHRM.S63060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489817PMC
April 2016

Lack of consistency in the relationship between asymptomatic DVT detected by venography and symptomatic VTE in thromboprophylaxis trials.

Thromb Haemost 2015 Nov 2;114(5):1049-57. Epub 2015 Jul 2.

Dr. Noel C Chan, Population Health Research Institute,, 237 Barton St E,, Hamilton ON L7L 2X2, Canada, Tel.: +1 905 527 4322 Ext 40520, Fax: +1 905 297 3785, E-mail:

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http://dx.doi.org/10.1160/TH14-12-1006DOI Listing
November 2015

Timing the First Postoperative Dose of Anticoagulants: Lessons Learned From Clinical Trials.

Chest 2015 Sep;148(3):587-595

Hamilton General Hospital, McMaster University, Hamilton, ON, Canada; Department of Medicine, McMaster University, Hamilton, ON, Canada; Population Health Research Institute, McMaster University, Hamilton, ON, Canada; Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1378/chest.14-2710DOI Listing
September 2015

Effect of a hospital policy of not accepting free infant formula on in-hospital formula supplementation rates and breast-feeding duration.

Public Health Nutr 2015 Oct 27;18(14):2689-99. Epub 2015 Feb 27.

7College of Nursing and Healthcare Innovation,Arizona State University,Phoenix,AZ,USA.

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http://dx.doi.org/10.1017/S1368980015000117DOI Listing
October 2015

Anatomical effects of clear lens extraction by phacoemulsification versus trabeculectomy on anterior chamber drainage angle in primary angle-closure glaucoma (PACG) patients.

Graefes Arch Clin Exp Ophthalmol 2015 May 3;253(5):773-8. Epub 2015 Feb 3.

Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China.

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http://dx.doi.org/10.1007/s00417-015-2936-zDOI Listing
May 2015

Role of phenotypic and genetic testing in managing clopidogrel therapy.

Blood 2014 Jul 20;124(5):689-99. Epub 2014 Jun 20.

Department of Medicine, McMaster University, Hamilton, Canada; and.

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http://dx.doi.org/10.1182/blood-2014-01-512723DOI Listing
July 2014

Histamine H4-receptors inhibit mast cell renin release in ischemia/reperfusion via protein kinase C ε-dependent aldehyde dehydrogenase type-2 activation.

J Pharmacol Exp Ther 2014 Jun 2;349(3):508-17. Epub 2014 Apr 2.

Department of Pharmacology, Weill Cornell Medical College, New York, New York, (S.A., K.-i.T., K.T., K.K., N.C., A.M., M.S.-R., R.L.); and Department of Immunology, Janssen Research & Development, L.L.C., San Diego, California (R.L.T.).

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http://dx.doi.org/10.1124/jpet.114.214122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019319PMC
June 2014

New oral anticoagulants for stroke prevention in atrial fibrillation: impact of study design, double counting and unexpected findings on interpretation of study results and conclusions.

Thromb Haemost 2014 May 20;111(5):798-807. Epub 2014 Feb 20.

Noel C. Chan, MBBS, Population Health Research Institute, 237 Barton St E,, Hamilton ON L7L 2X2, Canada, Tel.: +1 905 527 4322 Ext 40520, Fax: +1 905 297 3785, E-mail:

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http://dx.doi.org/10.1160/TH13-11-0918DOI Listing
May 2014

Betrixaban (PRT054021): pharmacology, dose selection and clinical studies.

Future Cardiol 2014 Jan;10(1):43-52

Thrombosis & Atherosclerosis Research Institute, C3-10 DBCVRSI, Hamilton General Hospital, 237 Barton Street East, Hamilton, ON L8L 2X2, Canada.

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http://dx.doi.org/10.2217/fca.13.98DOI Listing
January 2014

c-Kit-positive cardiac stem cells nested in hypoxic niches are activated by stem cell factor reversing the aging myopathy.

Circ Res 2014 Jan 29;114(1):41-55. Epub 2013 Oct 29.

From the Departments of Anesthesia (F.S., J.K., A.M.C., N.Y.-.K.C., S.S., B.O., K.I., E.W., G.B., A.P., A.S., E.M., D.C., C.M., M. Ricciardi, M.C., P.G., J.K., T.H., M. Rota, P.A., A.L.) and Medicine (F.S., J.K., A.M.C., N.Y.-.K.C., S.S., B.O., K.I., E.W., G.B., A.P., A.S., E.M., D.C., C.M., M. Ricciardi, M.C., E.I., M.A.P., P.G., J.K., T.H., M. Rota, P.A., A.L.), and Divisions of Cardiovascular Medicine (F.S., J.K., A.M.C., N.Y.-.K.C., S.S., B.O., K.I., E.W., G.B., A.P., A.S., E.M., D.C., C.M., M. Ricciardi, M.C., P.G., J.K., T.H., M. Rota, P.A., A.L.), Pulmonary and Critical Care Medicine (E.I., M.A.P., A.M.C.), and Newborn Medicine (M.A.P.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/CIRCRESAHA.114.302500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959163PMC
January 2014

Mandatory contrast-enhanced venography to detect deep-vein thrombosis (DVT) in studies of DVT prophylaxis: upsides and downsides.

Thromb Haemost 2014 Jan 10;111(1):10-3. Epub 2013 Oct 10.

John W. Eikelboom, Department of Medicine, McMaster University, Hamilton General Hospital, 237 Barton Street East, Hamilton, Ontario, L8L 2X2, Canada, E-mail:

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http://dx.doi.org/10.1160/TH13-07-0562DOI Listing
January 2014

The Pathogenesis of Nonarteritic Anterior Ischemic Optic Neuropathy.

Asia Pac J Ophthalmol (Phila) 2013 Mar-Apr;2(2):132-5

From the Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, PR China.

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http://dx.doi.org/10.1097/APO.0b013e3182902e45DOI Listing
June 2015

Natriuretic peptide-induced catecholamine release from cardiac sympathetic neurons: inhibition by histamine H3 and H4 receptor activation.

J Pharmacol Exp Ther 2012 Dec 24;343(3):568-77. Epub 2012 Aug 24.

Department of Pharmacology, Weill Cornell Medical College, New York, NY 10065, USA.

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http://dx.doi.org/10.1124/jpet.112.198747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500538PMC
December 2012

Acute and subacute inflammation of the optic nerve and its sheath: clinical features in Chinese patients.

Hong Kong Med J 2012 Apr;18(2):115-22

Department of Ophthalmology, Hong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong Kong.

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April 2012

Self-reported body weight and height: an assessment tool for identifying children with overweight/obesity status and cardiometabolic risk factors clustering.

Matern Child Health J 2013 Feb;17(2):282-91

Rm 322, 3rd floor, William M.W. Mong Block, The School of Nursing, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong.

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February 2013

Retinal Nerve Fiber Layer Imaging with Spectral-Domain Optical Coherence Tomography: Impact of Signal Strength on Analysis of the RNFL Map.

Asia Pac J Ophthalmol (Phila) 2012 Jan-Feb;1(1):19-23

From the Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, People's Republic of China.

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June 2015

Histamine 3 receptor activation reduces the expression of neuronal angiotensin II type 1 receptors in the heart.

J Pharmacol Exp Ther 2012 Jan 19;340(1):185-91. Epub 2011 Oct 19.

Department of Pharmacology, Weill Cornell Medical College, New York, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251025PMC
January 2012

Measurement of pubertal status with a Chinese self-report Pubertal Development Scale.

Matern Child Health J 2010 May 11;14(3):466-73. Epub 2009 Jun 11.

The Nethersole School of Nursing, The Chinese University of Hong Kong, Rm 621, 6th Floor, Esther Lee Building, Shatin, NT, Hong Kong SAR.

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May 2010

Reliability of pubertal self-assessment in Hong Kong Chinese children.

J Paediatr Child Health 2008 Jun;44(6):353-8

The Nethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.

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June 2008

Syntheses of nicotinamide riboside and derivatives: effective agents for increasing nicotinamide adenine dinucleotide concentrations in mammalian cells.

J Med Chem 2007 Dec 6;50(26):6458-61. Epub 2007 Dec 6.

Department of Pharmacology, Weill Medical College of Cornell University, Manhattan, NY 10021, USA.

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http://dx.doi.org/10.1021/jm701001cDOI Listing
December 2007

Is four a deadly number for the Chinese?

Med J Aust 2003 Dec 1-15;179(11-12):656-8

Department of Chemical Pathology, Faculty of Medicine, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, China.

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September 2007