Njira Lugogo

Njira Lugogo

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Njira Lugogo

Publications by authors named "Njira Lugogo"

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The Effects of Obesity in Asthma.

Curr Allergy Asthma Rep 2019 Sep 10;19(10):49. Epub 2019 Sep 10.

Division of Pulmonary and Critical Care Medicine, University of Michigan, 300 N Ingalls St Ste 2C40, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1007/s11882-019-0877-zDOI Listing
September 2019

Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma.

N Engl J Med 2019 09;381(13):1227-1239

From National Jewish Health (M.E.W., R.C., J.T.O.), Denver, and University of Colorado School of Medicine (M.E.W., S.J.S., R.C., F.H., J.T.O.) and Children's Hospital Colorado (S.J.S.), Aurora - all in Colorado; Wake Forest School of Medicine (V.E.O., W.C.M., S.P.P.), Winston-Salem, North Carolina Clinical Research (C.F.L.), Raleigh, and Duke University Medical Center (N.L., L.Q.), Durham - all in North Carolina; Ann and Robert H. Lurie Children's Hospital of Chicago (J.A.P., R.G.R.), University of Illinois at Chicago (J.A.K., H.K.), Rush University Medical Center (J.M.), University of Chicago (E.N., J.S., S. White), and Northwestern University Feinberg School of Medicine (L.J.S.) - all in Chicago; Penn State University (V.C., S.J.K., D.M.), Hershey, and Allegheny General Hospital (D.G.) and University of Pittsburgh Medical Center (S. Wenzel), Pittsburgh - all in Pennsylvania; Nemours Children's Health System, Jacksonville (J.J.L., K.V.B., J.L.), and University of South Florida Morsani College of Medicine, Tampa (J.-C.C.) - both in Florida; University of Arizona Health Sciences, Tucson (E.R.B., M.K., F.M., D.A.M.); Washington University School of Medicine, St. Louis (L.B.B., A.B., M.C.); University of California, San Francisco (UCSF), San Francisco (M.B., M.D.C., S.C.L., D.L.) and UCSF Benioff Children's Hospital, Oakland (M.B., D.L.) - both in California; Brigham and Women's Hospital and Harvard Medical School (J.-C.C., N.G., E.I.) and Boston Children's Hospital (W.P., W.S.) - all in Boston; University Hospitals Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland (J.F.C., K.R.); University of Wisconsin-Madison, Madison (L.D., D.J.J., R.F.L., C.A.S.) and Aurora Sinai Medical Center, Milwaukee (L.S.-V.) - both in Wisconsin; Columbia University Irving Medical Center, New York, (E.D.); Emory University, Atlanta (A.M.F.); and University of New Mexico, Albuquerque (H.R.).

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http://dx.doi.org/10.1056/NEJMoa1905560DOI Listing
September 2019

Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level.

N Engl J Med 2019 05 19;380(21):2009-2019. Epub 2019 May 19.

From the Division of Pulmonary and Critical Care Medicine and the Cardiovascular Research Institute (S.C.L., H.A.B., J.V.F., P.G.W.) and the Department of Pediatrics, Epidemiology, and Biostatistics (M.D.C.), University of California, San Francisco, San Francisco; the University of Illinois at Chicago (J.A.K.), the Department of Pediatrics, Rush University Medical Center (J.N.M.), Ann and Robert Lurie Children's Hospital of Chicago (J.A.P.), and Northwestern University, Feinberg School of Medicine (L.S.) - all in Chicago; the Department of Public Health Sciences, Penn State University, Hershey (T.S.K., V.M.C., D.T.M., A.-M.D.), and the University of Pittsburgh Asthma Institute (S.W., F.H.) and Allegheny General Hospital (D.G.), Pittsburgh - all in Pennsylvania; Nemours Children's Hospital, University of Central Florida College of Medicine, Orlando (J.E.L., K.V.B.), and Nemours Children's Health System, Jacksonville (J.E.L., K.V.B.) - both in Florida; the Department of Pediatrics and Medicine, National Jewish Health, Denver (R.C., S.J.S., M.E.W.), and Children's Hospital Colorado, Aurora (R.C., S.J.S., M.E.W.) - both in Colorado; Duke Allergy, Asthma, and Airway Center, Duke University School of Medicine, Durham (N.L., M.K., L.Q.), Wake Forest University School of Medicine, Winston-Salem (A.H., W.M., S.P.P.), and North Carolina Clinical Research, Raleigh (C.L.) - all in North Carolina; the Departments of Pediatrics and Medicine, Washington University in St. Louis School of Medicine, St. Louis (L.B.B., M.C.); Brigham and Women's Hospital and Harvard Medical School (J.C.C., E.I.) and Boston Children's Hospital (W.P.) - all in Boston; Rainbow Babies and Children's Hospital, Cleveland (J.C., R.M., K.R.); the University of Wisconsin, Madison (L.D., D.J., R.F.L., C.A.S.); Columbia University, New York (E.D.); the Department of Pediatrics, Emory University, Atlanta (A.M.F.); and the Arizona Respiratory Center, University of Arizona, Tucson (F.D.M., W.J.M.).

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http://dx.doi.org/10.1056/NEJMoa1814917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711475PMC
May 2019

Obesity and adult asthma: diagnostic and management challenges.

Curr Opin Pulm Med 2019 Jan;25(1):44-50

Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/MCP.0000000000000531DOI Listing
January 2019

Reply.

J Allergy Clin Immunol 2018 08 11;142(2):713-714. Epub 2018 Apr 11.

Department of Medicine, University of Arizona, Tucson, Ariz.

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http://dx.doi.org/10.1016/j.jaci.2018.02.030DOI Listing
August 2018

Assessing the impact of a remote digital coaching engagement program on patient-reported outcomes in asthma.

J Asthma 2018 07 11;55(7):795-800. Epub 2017 Oct 11.

e Duke University , Division of Pulmonary, Allergy, and Critical Care Medicine and Duke Asthma, Allergy and Airways Center , Durham , North Carolina , USA.

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http://dx.doi.org/10.1080/02770903.2017.1362430DOI Listing
July 2018

Effect of the S-nitrosoglutathione reductase inhibitor N6022 on bronchial hyperreactivity in asthma.

Immun Inflamm Dis 2018 06 11;6(2):322-331. Epub 2018 Apr 11.

Department of Medicine, College of Medicine, University of Arizona Health Sciences, Tucson, Arizona, USA.

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http://dx.doi.org/10.1002/iid3.220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946144PMC
June 2018

Medication Regimens for Managing Stable Asthma.

Respir Care 2018 Jun;63(6):759-772

Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.4187/respcare.05957DOI Listing
June 2018

Obese asthmatic patients have decreased surfactant protein A levels: Mechanisms and implications.

J Allergy Clin Immunol 2018 03 15;141(3):918-926.e3. Epub 2017 Jun 15.

Department of Medicine, University of Arizona, Tucson, Ariz; Department of Immunobiology, University of Arizona, Tucson, Ariz. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.05.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732097PMC
March 2018

Income is an independent risk factor for worse asthma outcomes.

J Allergy Clin Immunol 2018 02 20;141(2):754-760.e3. Epub 2017 May 20.

Department of Medicine, Brigham and Women's Hospital, Boston, Mass; the Division of Allergy and Immunology, Boston Children's Hospital, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.04.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696111PMC
February 2018

Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease.

N Engl J Med 2017 10 11;377(17):1613-1629. Epub 2017 Sep 11.

From the Respiratory Medicine Unit and Oxford Respiratory Biomedical Research Centre, Nuffield Department of Medicine, University of Oxford, Oxford (I.D.P.), and Clinical Statistics, GlaxoSmithKline, Uxbridge (B.M.) - both in the United Kingdom; the Department of Respiratory Medicine and CIC Nord, Aix-Marseille University, Marseille, France (P.C.); the Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia (G.J.C.); the Department of Pulmonary Medicine and Tuberculosis, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands (H.A.M.K.); the Pulmonary Department, Mainz University Hospital, Mainz, Germany (S.K.); the Division of Pulmonary, Allergy, and Critical Care Medicine, Duke University, Durham (N.L.), and the Respiratory Medical Franchise (F.C.A.) and the Respiratory Therapeutic Area (E.S.B., S.S.H., D.B.R., S.W.Y.), GlaxoSmithKline, Research Triangle Park - all in North Carolina; the Department of Pneumology, Centre Hospitalier Universitaire-Université Catholique de Louvain, Namur, Namur, Belgium (J.-B.M.); the Division of Allergology and Respiratory Medicine, Showa University School of Medicine, Tokyo (H.S.); and the Department of Medicine, University of Pittsburgh, Pittsburgh (F.C.S.).

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http://dx.doi.org/10.1056/NEJMoa1708208DOI Listing
October 2017

Oral Glucocorticoid-Sparing Effect of Benralizumab in Severe Asthma.

N Engl J Med 2017 06 22;376(25):2448-2458. Epub 2017 May 22.

From McMaster University and St. Joseph's Healthcare, Hamilton, ON, Canada (P.N.); University of Pittsburgh, Pittsburgh (S.W.); LungenClinic Grosshansdorf and Department of Medicine, Airway Research Center North of the German Center for Lung Research, Christian Albrechts University, Kiel, Germany (K.F.R.); Département de Pneumologie et Addictologie, PhyMedExp, University of Montpellier, INSERM Unité 1046, Centre National de la Recherche Scientifique Unité Mixte de Recherche 9214, Hôpital Arnaud de Villeneuve, Centre Hospitalier Universitaire de Montpellier, Montpellier, France (A.B.); Duke University Medical Center, Durham, NC (N.L.L.); Barlicki University Hospital, Medical University of Lodz, Lodz, Poland (P.K.); AstraZeneca, Gaithersburg, MD (P.B., S.S., M.G.); and AstraZeneca, Cambridge, United Kingdom (S.P.).

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http://dx.doi.org/10.1056/NEJMoa1703501DOI Listing
June 2017

Long-term Efficacy and Safety of Mepolizumab in Patients With Severe Eosinophilic Asthma: A Multi-center, Open-label, Phase IIIb Study.

Clin Ther 2016 Sep 21;38(9):2058-2070.e1. Epub 2016 Aug 21.

Respiratory Therapeutic Area, GlaxoSmithKline, Research Triangle Park, North Carolina.

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http://dx.doi.org/10.1016/j.clinthera.2016.07.010DOI Listing
September 2016

Raising the Profile of Pulmonary Education for Physicians in Low- and Middle-Income Countries.

Ann Am Thorac Soc 2016 Apr;13(4):458-9

3 Division of Pulmonary and Critical Care Medicine, Oregon Health and Sciences University, Portland, Oregon.

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http://dx.doi.org/10.1513/AnnalsATS.201601-085EDDOI Listing
April 2016

Role of weight management in asthma symptoms and control.

Immunol Allergy Clin North Am 2014 Nov 29;34(4):797-808. Epub 2014 Aug 29.

Department of Pulmonary and Critical Care, Duke University Medical Center, Durham, NC 27710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.iac.2014.07.009DOI Listing
November 2014

Waiting to inhale: An exploratory review of conditions that may predispose to pulmonary hypertension and right heart failure in persons exposed to household air pollution in low- and middle-income countries.

Glob Heart 2012 Sep;7(3):249-259

Division of Cardiology and Duke Clinical Research Institute, Duke University, 2400 Pratt Street, DUMC Box 3850, Durham, NC 27705; Division of Cardiology and Duke Clinical Research Institute, Duke University, 2400 Pratt Street, DUMC Box 3850, Durham, NC 27705,

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https://linkinghub.elsevier.com/retrieve/pii/S22118160120007
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http://dx.doi.org/10.1016/j.gheart.2012.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653331PMC
September 2012

Obesity, metabolic dysregulation and oxidative stress in asthma.

Biochim Biophys Acta 2011 Nov 14;1810(11):1120-6. Epub 2011 Sep 14.

Department of Medicine, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1016/j.bbagen.2011.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786599PMC
November 2011

Surfactant protein A is defective in abrogating inflammation in asthma.

Am J Physiol Lung Cell Mol Physiol 2011 Oct 22;301(4):L598-606. Epub 2011 Jul 22.

Department of Medicine and Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1152/ajplung.00381.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191759PMC
October 2011

Airway fibroblasts in asthma manifest an invasive phenotype.

Am J Respir Crit Care Med 2011 Jun 25;183(12):1625-32. Epub 2011 Mar 25.

Department of Medicine, Duke University Medical Center, 201 MSRB 1, Research Drive, Box 2641, Durham, NC 27710, USA.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.201009-1452O
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http://dx.doi.org/10.1164/rccm.201009-1452OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136991PMC
June 2011

Does obesity produce a distinct asthma phenotype?

J Appl Physiol (1985) 2010 Mar 29;108(3):729-34. Epub 2009 Oct 29.

Department of Medicine, Duke University, Durham, North Carolina, USA.

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http://dx.doi.org/10.1152/japplphysiol.00845.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838637PMC
March 2010

S-nitrosoglutathione reductase: an important regulator in human asthma.

Am J Respir Crit Care Med 2009 Aug 24;180(3):226-31. Epub 2009 Apr 24.

Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1164/rccm.200901-0158OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724715PMC
August 2009

Life-threatening asthma: pathophysiology and management.

Respir Care 2008 Jun;53(6):726-35; discussion 735-9

Respiratory Care Services, Duke University Medical Center, Durham, NC 27710, USA.

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June 2008

Genetic profiling and tailored therapy in asthma: are we there yet?

Curr Opin Mol Ther 2007 Dec;9(6):528-37

Duke University Medical Center, Division of Pulmonary, Allergy and Critical Care Medicine, PO Box 2629, Durham, NC 27710, USA.

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December 2007

Epidemiology of asthma.

Clin Chest Med 2006 Mar;27(1):1-15, v

Division of Pulmonary, Allergy, and Critical Care Medicine, Duke University Medical Center, P.O. Box 2641, Durham, NC 27710, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S02725231050012
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http://dx.doi.org/10.1016/j.ccm.2005.10.006DOI Listing
March 2006