Publications by authors named "Nizar Serhan"

16 Publications

  • Page 1 of 1

Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells.

Authors:
Clément Larrue Nathan Guiraud Pierre-Luc Mouchel Marine Dubois Thomas Farge Mathilde Gotanègre Claudie Bosc Estelle Saland Marie-Laure Nicolau-Travers Marie Sabatier Nizar Serhan Ambrine Sahal Emeline Boet Sarah Mouche Quentin Heydt Nesrine Aroua Lucille Stuani Tony Kaoma Linus Angenendt Jan-Henrik Mikesch Christoph Schliemann François Vergez Jérôme Tamburini Christian Récher Jean-Emmanuel Sarry

Nat Commun 2021 01 18;12(1):422. Epub 2021 Jan 18.

Centre de Recherches en Cancérologie de Toulouse, UMR1037, Inserm, Université de Toulouse 3 Paul Sabatier, Equipe Labellisée LIGUE 2018, F-31037, Toulouse, France.

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January 2021

Dendrogenin A Enhances Anti-Leukemic Effect of Anthracycline in Acute Myeloid Leukemia.

Authors:
Pierre-Luc Mouchel Nizar Serhan Rémy Betous Thomas Farge Estelle Saland Philippe De Medina Jean-Sébastien Hoffmann Jean-Emmanuel Sarry Marc Poirot Sandrine Silvente-Poirot Christian Récher

Cancers (Basel) 2020 Oct 12;12(10). Epub 2020 Oct 12.

Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, 31059 Toulouse, France.

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October 2020

Dendrogenin A synergizes with Cytarabine to Kill Acute Myeloid Leukemia Cells In Vitro and In Vivo.

Authors:
Nizar Serhan Pierre-Luc Mouchel Philippe de Medina Gregory Segala Aurélie Mougel Estelle Saland Arnaud Rives Antonin Lamaziere Gaëtan Despres Jean-Emmanuel Sarry Clément Larrue François Vergez Laetitia Largeaud Michel Record Christian Récher Sandrine Silvente-Poirot Marc Poirot

Cancers (Basel) 2020 Jun 29;12(7). Epub 2020 Jun 29.

Unité Mixte de Recherche (UMR)1037, Cancer Research Center of Toulouse (CRCT), Institut National de la Santé et de la Recherche Médicale (INSERM) Université de Toulouse, Team Cholesterol Metabolism and Therapeutic Innovations, Equipe labellisée par la Ligue Contre le Cancer, 31037 Toulouse, France.

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June 2020

Combined Treatments of Magnetic Intra-Lysosomal Hyperthermia with Doxorubicin Promotes Synergistic Anti-Tumoral Activity.

Authors:
Darine El Hajj Diab Pascal Clerc Nizar Serhan Daniel Fourmy Véronique Gigoux

Nanomaterials (Basel) 2018 Jun 27;8(7). Epub 2018 Jun 27.

INSERM ERL1226-Receptology and Therapeutic Targeting of Cancers, Laboratoire de Physique et Chimie des Nano-Objets, CNRS UMR5215-INSA, Université de Toulouse III, F-31432 Toulouse, France.

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June 2018

Dendrogenin A drives LXR to trigger lethal autophagy in cancers.

Authors:
Gregory Segala Marion David Philippe de Medina Mathias C Poirot Nizar Serhan François Vergez Aurelie Mougel Estelle Saland Kevin Carayon Julie Leignadier Nicolas Caron Maud Voisin Julia Cherier Laetitia Ligat Frederic Lopez Emmanuel Noguer Arnaud Rives Bruno Payré Talal Al Saati Antonin Lamaziere Gaëtan Despres Jean-Marc Lobaccaro Silvere Baron Cecile Demur Fabienne de Toni Clément Larrue Helena Boutzen Fabienne Thomas Jean-Emmanuel Sarry Marie Tosolini Didier Picard Michel Record Christian Récher Marc Poirot Sandrine Silvente-Poirot

Nat Commun 2017 12 4;8(1):1903. Epub 2017 Dec 4.

UMR 1037-CRCT, Université de Toulouse, INSERM, UPS, Cholesterol Metabolism and Therapeutic Innovations Team, Toulouse, F-31037, France.

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December 2017

Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor.

Authors:
Maud Voisin Philippe de Medina Arnaud Mallinger Florence Dalenc Emilie Huc-Claustre Julie Leignadier Nizar Serhan Régis Soules Grégory Ségala Aurélie Mougel Emmanuel Noguer Loubna Mhamdi Elodie Bacquié Luigi Iuliano Chiara Zerbinati Magali Lacroix-Triki Léonor Chaltiel Thomas Filleron Vincent Cavaillès Talal Al Saati Philippe Rochaix Raphaelle Duprez-Paumier Camille Franchet Laetitia Ligat Fréderic Lopez Michel Record Marc Poirot Sandrine Silvente-Poirot

Proc Natl Acad Sci U S A 2017 10 12;114(44):E9346-E9355. Epub 2017 Oct 12.

Team "Cholesterol Metabolism and Therapeutic Innovations," Cancer Research Center of Toulouse (CRCT), UMR 1037, Université de Toulouse, CNRS, Inserm, UPS, 31037 Toulouse, France;

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October 2017

Quantitative analysis of the tumor suppressor dendrogenin A using liquid chromatography tandem mass spectrometry.

Authors:
Emmanuel Noguer Régis Soules Claude Netter Citra Nagarathinam Julie Leignadier Emilie Huc-Claustre Nizar Serhan Arnaud Rives Philippe de Medina Sandrine Silvente-Poirot Marc Poirot

Chem Phys Lipids 2017 10 3;207(Pt B):81-86. Epub 2017 Jul 3.

Inserm UMR 1037, Team "Cholesterol Metabolism and Therapeutic Innovations", Cancer Research Center of Toulouse, Toulouse, France; University of Toulouse III, Toulouse, France. Electronic address:

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October 2017

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism.

Authors:
Thomas Farge Estelle Saland Fabienne de Toni Nesrine Aroua Mohsen Hosseini Robin Perry Claudie Bosc Mayumi Sugita Lucille Stuani Marine Fraisse Sarah Scotland Clément Larrue Héléna Boutzen Virginie Féliu Marie-Laure Nicolau-Travers Stéphanie Cassant-Sourdy Nicolas Broin Marion David Nizar Serhan Audrey Sarry Suzanne Tavitian Tony Kaoma Laurent Vallar Jason Iacovoni Laetitia K Linares Camille Montersino Rémy Castellano Emmanuel Griessinger Yves Collette Olivier Duchamp Yara Barreira Pierre Hirsch Tony Palama Lara Gales François Delhommeau Barbara H Garmy-Susini Jean-Charles Portais François Vergez Mary Selak Gwenn Danet-Desnoyers Martin Carroll Christian Récher Jean-Emmanuel Sarry

Cancer Discov 2017 07 17;7(7):716-735. Epub 2017 Apr 17.

Inserm, Cancer Research Center of Toulouse, U1037, Toulouse, France.

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July 2017

Antileukemic Activity of 2-Deoxy-d-Glucose through Inhibition of N-Linked Glycosylation in Acute Myeloid Leukemia with FLT3-ITD or c-KIT Mutations.

Authors:
Clément Larrue Estelle Saland François Vergez Nizar Serhan Eric Delabesse Véronique Mansat-De Mas Marie-Anne Hospital Jérôme Tamburini Stéphane Manenti Jean Emmanuel Sarry Christian Récher

Mol Cancer Ther 2015 Oct 23;14(10):2364-73. Epub 2015 Jul 23.

Cancer Research Center of Toulouse (CRCT), UMR1037 INSERM, ERL5294 CNRS, Toulouse, France. Université Toulouse III Paul Sabatier, Toulouse, France. Service d'Hématologie, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France.

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October 2015

Increased atherosclerosis in P2Y13/apolipoprotein E double-knockout mice: contribution of P2Y13 to reverse cholesterol transport.

Authors:
Laeticia Lichtenstein Nizar Serhan Sara Espinosa-Delgado Aurélie Fabre Wijtske Annema Uwe J F Tietge Bernard Robaye Jean-Marie Boeynaems Muriel Laffargue Bertrand Perret Laurent O Martinez

Cardiovasc Res 2015 May 13;106(2):314-23. Epub 2015 Mar 13.

INSERM, UMR 1048, Institut de Maladies Métaboliques et Cardiovasculaires, Toulouse, France Université de Toulouse III, UMR 1048, Toulouse, France CHU de Toulouse, Hôpital Purpan, Toulouse, France INSERM U1048, Bât. L3, Hôpital Rangueil, BP 84225, 31432 Toulouse cedex 04, France

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May 2015

Lack of P2Y13 in mice fed a high cholesterol diet results in decreased hepatic cholesterol content, biliary lipid secretion and reverse cholesterol transport.

Authors:
Laeticia Lichtenstein Nizar Serhan Wijtske Annema Guillaume Combes Bernard Robaye Jean-Marie Boeynaems Bertrand Perret Uwe J F Tietge Muriel Laffargue Laurent O Martinez

Nutr Metab (Lond) 2013 Nov 6;10(1):67. Epub 2013 Nov 6.

INSERM, UMR 1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse 31432, France.

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November 2013

Resveratrol mainly stimulates the glycolytic ATP synthesis flux and not the mitochondrial one: a saturation transfer NMR study in perfused and isolated rat liver.

Authors:
Marie-Christine Beauvieux Alan Stephant Henri Gin Nizar Serhan Patrice Couzigou Jean-Louis Gallis

Pharmacol Res 2013 Dec 1;78:11-7. Epub 2013 Oct 1.

Centre de Résonance Magnétique des Systèmes Biologiques, UMR 5536 CNRS-Université, Bordeaux Segalen, LabEx TRAIL-IBIO, 146 rue Léo Saignat, F-33076 Bordeaux Cedex, France. Electronic address:

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December 2013

Role of the ubiquitin-proteasome system in the regulation of P2Y13 receptor expression: impact on hepatic HDL uptake.

Authors:
Véronique Pons Nizar Serhan Stéphanie Gayral Camille Malaval Michel Nauze Nicole Malet Muriel Laffargue Céline Galés Laurent O Martinez

Cell Mol Life Sci 2014 May 13;71(9):1775-88. Epub 2013 Sep 13.

INSERM, UMR 1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, 31432, France,

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May 2014

Chronic pharmacological activation of P2Y13 receptor in mice decreases HDL-cholesterol level by increasing hepatic HDL uptake and bile acid secretion.

Authors:
Nizar Serhan Cendrine Cabou Céline Verdier Laeticia Lichtenstein Nicole Malet Bertrand Perret Muriel Laffargue Laurent O Martinez

Biochim Biophys Acta 2013 Apr 20;1831(4):719-25. Epub 2012 Dec 20.

INSERM, UMR 1048, Institut de Maladies Métaboliques et Cardiovasculaires, Toulouse, 31000, France.

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April 2013

Resveratrol plus ethanol counteract the ethanol-induced impairment of energy metabolism: ³¹P NMR study of ATP and sn-glycerol-3-phosphate on isolated and perfused rat liver.

Authors:
Jean-Louis Gallis Nizar Serhan Henri Gin Patrice Couzigou Marie-Christine Beauvieux

Pharmacol Res 2012 Mar 28;65(3):387-95. Epub 2011 Dec 28.

Centre de Résonance Magnétique des Systèmes Biologiques, UMR 5536 CNRS-Université Bordeaux Segalen, LabEx TRAIL-IBIO, 146 Rue Léo Saignat, F-33076 Bordeaux Cedex, France.

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March 2012

P2Y13 receptor is critical for reverse cholesterol transport.

Authors:
Aurélie C Fabre Camille Malaval Abduelhakem Ben Addi Céline Verdier Véronique Pons Nizar Serhan Laeticia Lichtenstein Guillaume Combes Thierry Huby François Briand Xavier Collet Niels Nijstad Uwe J F Tietge Bernard Robaye Bertrand Perret Jean-Marie Boeynaems Laurent O Martinez

Hepatology 2010 Oct;52(4):1477-83

Institut National de la Santé et de la Recherche Médicale (INSERM), Unit 563, Toulouse, France.

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October 2010