Ningshao Xia

Ningshao Xia

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Molecular epidemiology of group A rotavirus in outpatient diarrhea infants and children in Chongqing, China, 2011-2015.

J Med Virol 2019 Oct 12;91(10):1788-1796. Epub 2019 Jul 12.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Disease, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.1002/jmv.25530DOI Listing
October 2019

Transcriptional response of USP18 predicts treatment outcomes of interferon-alpha in HBeAg-positive chronic hepatitis B patientsefere.

J Viral Hepat 2019 Sep 2;26(9):1050-1058. Epub 2019 Jun 2.

State key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.1111/jvh.13120DOI Listing
September 2019

HIV-1 Membrane-Proximal External Region Fused to Diphtheria Toxin Domain-A Elicits 4E10-Like Antibodies in Mice.

Immunol Lett 2019 Sep 26;213:30-38. Epub 2019 Jul 26.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China; National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Life Sciences, Xiamen University, Xiamen 361102, China.

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http://dx.doi.org/10.1016/j.imlet.2019.07.004DOI Listing
September 2019

Sex differences in the incidence and clearance of anal human papillomavirus infection among heterosexual men and women in Liuzhou, China: An observational cohort study.

Int J Cancer 2019 Aug 22;145(3):807-816. Epub 2019 Mar 22.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen, Fujian, China.

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http://dx.doi.org/10.1002/ijc.32255DOI Listing
August 2019

Prevalence, Concordance, and Transmission of Human Papillomavirus Infection Among Heterosexual Couples in Liuzhou, China: An Observational Perspective Study.

J Infect Dis 2019 Aug;220(6):980-989

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University.

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http://dx.doi.org/10.1093/infdis/jiz224DOI Listing
August 2019

Altered antigenicity and immunogenicity of human papillomavirus virus-like particles in the presence of thimerosal.

Eur J Pharm Biopharm 2019 Aug 30;141:221-231. Epub 2019 May 30.

National Institute of Diagnostics and Vaccine Development in Infectious Diseases, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejpb.2019.05.027DOI Listing
August 2019

An efficient isothermal PCR method for on-site detection of nucleic acid.

Biotechniques 2019 Aug 24;67(2):63-69. Epub 2019 Jun 24.

State Key Laboratory of Molecular Vaccinology & Molecular Diagnostics, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.2144/btn-2018-0190DOI Listing
August 2019

The distinct impact of maternal antibodies on the immunogenicity of live and recombinant rotavirus vaccines.

Vaccine 2019 Jul 7;37(30):4061-4067. Epub 2019 Jun 7.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Disease, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen 361102, China.

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http://dx.doi.org/10.1016/j.vaccine.2019.05.086DOI Listing
July 2019

Intermittent abortive reactivation of Epstein-Barr virus during the progression of nasopharyngeal cancer as indicated by elevated antibody levels.

Oral Oncol 2019 Jun 30;93:85-90. Epub 2019 Apr 30.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Science and School of Public Health, Xiamen University, Xiamen 361102, Fujian, PR China.

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https://linkinghub.elsevier.com/retrieve/pii/S13688375193013
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http://dx.doi.org/10.1016/j.oraloncology.2019.04.024DOI Listing
June 2019

Immunogenicity noninferiority study of 2 doses and 3 doses of an Escherichia coli-produced HPV bivalent vaccine in girls vs. 3 doses in young women.

Sci China Life Sci 2019 Jun 21. Epub 2019 Jun 21.

The State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Collaborative Innovation Center of Biologic Products, School of Public Health, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1007/s11427-019-9547-7DOI Listing
June 2019

Hepatitis E vaccine candidate harboring a non-particulate immunogen of E2 fused with CRM197 fragment A.

Antiviral Res 2019 Apr 23;164:154-161. Epub 2019 Feb 23.

National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Life Sciences, Xiamen University, Xiamen, 361102, China; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1016/j.antiviral.2019.02.013DOI Listing
April 2019

Vesicular Antibodies: A Bioactive Multifunctional Combination Platform for Targeted Therapeutic Delivery and Cancer Immunotherapy.

Adv Mater 2019 Apr 7;31(17):e1808294. Epub 2019 Mar 7.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics and National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Public Health, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1002/adma.201808294DOI Listing
April 2019

Construction of a bacterial surface display system based on outer membrane protein F.

Microb Cell Fact 2019 Apr 11;18(1):70. Epub 2019 Apr 11.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, Xiamen University, Xiamen, 361102, China.

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https://microbialcellfactories.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12934-019-1120-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458713PMC
April 2019

[Progress in vaccine development based on baculovirus expression vector system].

Sheng Wu Gong Cheng Xue Bao 2019 Apr;35(4):577-588

National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Life Sciences, Xiamen University, Xiamen 361102, Fujian, China.

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http://dx.doi.org/10.13345/j.cjb.180301DOI Listing
April 2019

Agonist c-Met Monoclonal Antibody Augments the Proliferation of hiPSC-derived Hepatocyte-Like Cells and Improves Cell Transplantation Therapy for Liver Failure in Mice.

Theranostics 2019 6;9(7):2115-2128. Epub 2019 Apr 6.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, PR China.

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http://www.thno.org/v09p2115.htm
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http://dx.doi.org/10.7150/thno.30009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485278PMC
April 2019

An HRP-labeled lateral flow immunoassay for rapid simultaneous detection and differentiation of influenza A and B viruses.

J Med Virol 2019 Mar 31;91(3):503-507. Epub 2018 Oct 31.

Department of Experimental Medicine, State Key Laboratory of Molecular Vaccine and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.1002/jmv.25322DOI Listing
March 2019

Characterization of native-like HIV-1 gp140 glycoprotein expressed in insect cells.

Vaccine 2019 Mar 5;37(11):1418-1427. Epub 2019 Feb 5.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, Xiamen University, Xiamen 361102, China; National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Public Health, Xiamen University, Xiamen 361102, China.

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X193012
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http://dx.doi.org/10.1016/j.vaccine.2019.01.048DOI Listing
March 2019

Sex differences in the incidence and clearance of anogenital human papillomavirus infection in Liuzhou, China: an observational cohort study.

Clin Infect Dis 2019 Mar 10. Epub 2019 Mar 10.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen, Fujian, China.

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http://dx.doi.org/10.1093/cid/ciz168DOI Listing
March 2019

Development of an efficient neutralization assay for Coxsackievirus A10.

Appl Microbiol Biotechnol 2019 Feb 8;103(4):1931-1938. Epub 2019 Jan 8.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, 361102, People's Republic of China.

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http://link.springer.com/10.1007/s00253-018-09598-7
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http://dx.doi.org/10.1007/s00253-018-09598-7DOI Listing
February 2019

Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization.

Nat Microbiol 2019 01 5;4(1):124-133. Epub 2018 Nov 5.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Science, School of Public Health, Xiamen University, Xiamen, China.

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http://www.nature.com/articles/s41564-018-0275-7
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http://dx.doi.org/10.1038/s41564-018-0275-7DOI Listing
January 2019

A bispecific broadly neutralizing antibody against enterovirus 71 and coxsackievirus A16 with therapeutic potential.

Antiviral Res 2019 Jan 9;161:28-35. Epub 2018 Nov 9.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, 361102, PR China.

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https://linkinghub.elsevier.com/retrieve/pii/S01663542183046
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http://dx.doi.org/10.1016/j.antiviral.2018.11.001DOI Listing
January 2019

An Optimized High-Throughput Neutralization Assay for Hepatitis E Virus (HEV) Involving Detection of Secreted Porf2.

Viruses 2019 01 15;11(1). Epub 2019 Jan 15.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, Xiamen University, Xiamen 361102, Fujian, China.

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http://www.mdpi.com/1999-4915/11/1/64
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http://dx.doi.org/10.3390/v11010064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356577PMC
January 2019

An IgM antibody targeting the receptor binding site of influenza B blocks viral infection with great breadth and potency.

Theranostics 2019 1;9(1):210-231. Epub 2019 Jan 1.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.

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http://dx.doi.org/10.7150/thno.28434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332795PMC
January 2019

HBV infection-induced liver cirrhosis development in dual-humanised mice with human bone mesenchymal stem cell transplantation.

Gut 2019 Jan 30. Epub 2019 Jan 30.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences and School of Public Health, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.1136/gutjnl-2018-316091DOI Listing
January 2019

Characterization and epitope mapping of a panel of monoclonal antibodies against HIV-1 matrix protein.

Biotechnol Appl Biochem 2018 Nov 25;65(6):807-815. Epub 2018 Apr 25.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, People's Republic of China.

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http://dx.doi.org/10.1002/bab.1662DOI Listing
November 2018

Development of multiplex real-time reverse-transcriptase polymerase chain reaction assay for simultaneous detection of Zika, dengue, yellow fever, and chikungunya viruses in a single tube.

J Med Virol 2018 11 16;90(11):1681-1686. Epub 2018 Aug 16.

National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, Xiamen University, Xiamen, China.

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http://doi.wiley.com/10.1002/jmv.25253
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http://dx.doi.org/10.1002/jmv.25253DOI Listing
November 2018

Multifaceted characterization of recombinant protein-based vaccines: An immunochemical toolbox for epitope-specific analyses of the hepatitis E vaccine.

Vaccine 2018 11 2;36(50):7650-7658. Epub 2018 Nov 2.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiamen, Fujian 361005, PR China; School of Public Health, Xiamen University, Xiamen, Fujian 361005, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X183148
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http://dx.doi.org/10.1016/j.vaccine.2018.10.089DOI Listing
November 2018

T = 4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display.

Viruses 2018 11 26;10(12). Epub 2018 Nov 26.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.

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http://dx.doi.org/10.3390/v10120667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316451PMC
November 2018

Epitope clustering analysis for vaccine-induced human antibodies in relationship to a panel of murine monoclonal antibodies against HPV16 viral capsid.

Vaccine 2018 10 1;36(45):6761-6771. Epub 2018 Oct 1.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiamen, Fujian, PR China; School of Public Health, Xiamen University, Xiamen, Fujian, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2018.09.035DOI Listing
October 2018

An automated microfluidic chemiluminescence immunoassay platform for quantitative detection of biomarkers.

Biomed Microdevices 2018 10 25;20(4):91. Epub 2018 Oct 25.

National Institute of Diagnostics and Vaccine Development in Infectious Disease, Xiamen, Fujian, China.

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http://link.springer.com/10.1007/s10544-018-0331-3
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http://dx.doi.org/10.1007/s10544-018-0331-3DOI Listing
October 2018

Structural Basis for the Broad, Antibody-Mediated Neutralization of H5N1 Influenza Virus.

J Virol 2018 09 16;92(17). Epub 2018 Aug 16.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, Xiamen University, Xiamen, China

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http://dx.doi.org/10.1128/JVI.00547-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096824PMC
September 2018

Bioinspired Artificial Nanodecoys for Hepatitis B Virus.

Angew Chem Int Ed Engl 2018 09 23;57(38):12499-12503. Epub 2018 Aug 23.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, 361102, China.

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http://doi.wiley.com/10.1002/anie.201807212
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http://dx.doi.org/10.1002/anie.201807212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447037PMC
September 2018

N-terminal truncations on L1 proteins of human papillomaviruses promote their soluble expression in Escherichia coli and self-assembly in vitro.

Emerg Microbes Infect 2018 Sep 26;7(1):160. Epub 2018 Sep 26.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, Xiamen University, 361102, Xiamen, China.

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http://dx.doi.org/10.1038/s41426-018-0158-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156512PMC
September 2018

Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.

Sci Adv 2018 09 19;4(9):eaat7459. Epub 2018 Sep 19.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Science, School of Public Health, Xiamen University, Xiamen 361102, P.R. China.

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http://dx.doi.org/10.1126/sciadv.aat7459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155056PMC
September 2018

Quantification of HBV core antibodies may help predict HBV reactivation in patients with lymphoma and resolved HBV infection.

J Hepatol 2018 08 16;69(2):286-292. Epub 2018 Mar 16.

Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan; National Taiwan University Cancer Center, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.02.033DOI Listing
August 2018

Optimized HepaRG is a suitable cell source to generate the human liver chimeric mouse model for the chronic hepatitis B virus infection.

Emerg Microbes Infect 2018 Aug 10;7(1):144. Epub 2018 Aug 10.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Science, School of Public Health, Xiamen University, 361102, Xiamen, P. R. China.

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http://dx.doi.org/10.1038/s41426-018-0143-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086841PMC
August 2018

Efficient mAb production in CHO cells with optimized signal peptide, codon, and UTR.

Appl Microbiol Biotechnol 2018 Jul 8;102(14):5953-5964. Epub 2018 May 8.

National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1007/s00253-018-8986-5DOI Listing
July 2018

Identification of Strategic Residues at the Interface of Antigen-Antibody Interactions by In Silico Mutagenesis.

Interdiscip Sci 2018 Jun 30;10(2):438-448. Epub 2017 May 30.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361002, Fujian, People's Republic of China.

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http://dx.doi.org/10.1007/s12539-017-0242-7DOI Listing
June 2018

Efficient development of a stable cell pool for antibody production using a single plasmid.

J Biochem 2018 May;163(5):391-398

National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiamen 361102, People's Republic of China.

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http://dx.doi.org/10.1093/jb/mvy007DOI Listing
May 2018

Development and evaluation of a rapid point-of-care test for detecting the hepatitis E virus antigen.

Clin Biochem 2018 May 5;55:89-92. Epub 2018 Mar 5.

National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, PR China; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, Fujian 361005, PR China.

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http://dx.doi.org/10.1016/j.clinbiochem.2018.03.001DOI Listing
May 2018

An emerging and expanding clade accounts for the persistent outbreak of Coxsackievirus A6-associated hand, foot, and mouth disease in China since 2013.

Virology 2018 05 26;518:328-334. Epub 2018 Mar 26.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Xiamen University, Xiang'an Campus of Xiamen University, South Xiang'an Rd., Xiamen, China; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiang'an Campus of Xiamen University, South Xiang'an Rd., Xiamen, China; School of Public Health, Xiamen University, Xiang'an Campus of Xiamen University, South Xiang'an Rd., Xiamen, China. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2018.03.012DOI Listing
May 2018

Origin, antigenicity, and function of a secreted form of ORF2 in hepatitis E virus infection.

Proc Natl Acad Sci U S A 2018 05 18;115(18):4773-4778. Epub 2018 Apr 18.

Center for Vaccines and Immunity, The Research Institute at Nationwide Children's Hospital, Columbus, OH 43205;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1721345115
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http://dx.doi.org/10.1073/pnas.1721345115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939091PMC
May 2018

The gRNA-miRNA-gRNA Ternary Cassette Combining CRISPR/Cas9 with RNAi Approach Strongly Inhibits Hepatitis B Virus Replication.

Theranostics 2017 22;7(12):3090-3105. Epub 2017 Jul 22.

State Key Laboratory of Natural and Biomimetic Drugs, Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.

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http://dx.doi.org/10.7150/thno.18114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566108PMC
April 2018

A Single-Bead-Based, Fully Integrated Microfluidic System for High-Throughput CD4+T Lymphocyte Enumeration.

SLAS Technol 2018 04 13;23(2):134-143. Epub 2017 Oct 13.

5 Institute of Micro/Nanotechnology, Old Dominion University, Norfolk, VA, USA.

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http://dx.doi.org/10.1177/2472630317737016DOI Listing
April 2018

IL-6 release of Rv0183 antigen-stimulated whole blood is a potential biomarker for active tuberculosis patients.

J Infect 2018 Apr 24;76(4):376-382. Epub 2017 Nov 24.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, Fujian 361102, PR China; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Science, Xiamen University, Xiamen, Fujian 361102, PR China.

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http://dx.doi.org/10.1016/j.jinf.2017.11.004DOI Listing
April 2018

A Rapid On-Site Assay for the Detection of Influenza A by Capillary Convective PCR.

Mol Diagn Ther 2018 04;22(2):225-234

National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiang'an Campus of Xiamen University, Xiang'an South Road, Xiang'an District, Xiamen, Fujian, China.

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http://dx.doi.org/10.1007/s40291-018-0320-5DOI Listing
April 2018

Establishment and validation of a two-step screening scheme for improved performance of serological screening of nasopharyngeal carcinoma.

Cancer Med 2018 04 25;7(4):1458-1467. Epub 2018 Feb 25.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health and School of Life Science, Xiamen University, Xiamen, Fujian, China.

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http://dx.doi.org/10.1002/cam4.1345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911604PMC
April 2018

Expression, Purification and Characterization of Hiv-1 Capsid Precursor Protein p41.

Protein J 2018 04;37(2):194-202

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, China.

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http://link.springer.com/10.1007/s10930-018-9763-0
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http://dx.doi.org/10.1007/s10930-018-9763-0DOI Listing
April 2018

Characterization of capsid protein (p495) of hepatitis E virus expressed in Escherichia coli and assembling into particles in vitro.

Vaccine 2018 04 12;36(16):2104-2111. Epub 2018 Mar 12.

National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Life Sciences, Xiamen University, Xiamen 361102, China; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X183034
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http://dx.doi.org/10.1016/j.vaccine.2018.03.005DOI Listing
April 2018

Expression and characterization of a novel truncated rotavirus VP4 for the development of a recombinant rotavirus vaccine.

Vaccine 2018 04 16;36(16):2086-2092. Epub 2018 Mar 16.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Disease, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health and School of Life Science, Xiamen University, Xiamen 361102, China.

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X183034
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http://dx.doi.org/10.1016/j.vaccine.2018.03.011DOI Listing
April 2018

[Expression and self-assembly of HIV-1 CAP2NC protein].

Sheng Wu Gong Cheng Xue Bao 2018 Apr;34(4):586-593

National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Life Sciences, Xiamen University, Xiamen 361102, Fujian, China.

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http://dx.doi.org/10.13345/j.cjb.170380DOI Listing
April 2018

The prevalence and concordance of human papillomavirus infection in different anogenital sites among men and women in Liuzhou, China: A population-based study.

Int J Cancer 2018 03 17;142(6):1244-1251. Epub 2017 Nov 17.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China.

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http://dx.doi.org/10.1002/ijc.31128DOI Listing
March 2018

Cytomegalovirus Shedding in Healthy Seropositive Female College Students: A 6-Month Longitudinal Study.

J Infect Dis 2018 03;217(7):1069-1073

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.1093/infdis/jix679DOI Listing
March 2018

Rapid enumeration of CD4 + T lymphocytes using an integrated microfluidic system based on Chemiluminescence image detection at point-of-care testing.

Biomed Microdevices 2018 02 8;20(1):15. Epub 2018 Feb 8.

Institute of Micro/Nanotechnology, Old Dominion University, Norfolk, VA, 23529, USA.

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http://dx.doi.org/10.1007/s10544-018-0263-yDOI Listing
February 2018

A novel therapeutic anti-HBV antibody with increased binding to human FcRn improves in vivo PK in mice and monkeys.

Protein Cell 2018 01;9(1):130-134

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, School of Life Science, Xiamen University, Xiamen, 361105, China.

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http://dx.doi.org/10.1007/s13238-017-0438-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777975PMC
January 2018

Molecular and functional analysis of monoclonal antibodies in support of biologics development.

Protein Cell 2018 01 21;9(1):74-85. Epub 2017 Jul 21.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361105, China.

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http://dx.doi.org/10.1007/s13238-017-0447-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777976PMC
January 2018

Serological survey of neutralizing antibodies to eight major enteroviruses among healthy population.

Emerg Microbes Infect 2018 Jan 10;7(1). Epub 2018 Jan 10.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1038/s41426-017-0003-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837151PMC
January 2018

Outer nuclear membrane fusion of adjacent nuclei in varicella-zoster virus-induced syncytia.

Virology 2017 12 11;512:34-38. Epub 2017 Sep 11.

Department of Microbiology and Molecular Genetics, New Jersey Medical School, Rutgers University, 225 Warren Street, Newark, NJ 070101, USA. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2017.09.002DOI Listing
December 2017

Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide analogs.

Front Med 2017 Dec 23;11(4):502-508. Epub 2017 Nov 23.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1007/s11684-017-0590-zDOI Listing
December 2017

Incidence of anogenital warts in Liuzhou, south China: a comparison of data from a prospective study and from the national surveillance system.

Emerg Microbes Infect 2017 Dec 20;6(12):e113. Epub 2017 Dec 20.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.

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http://dx.doi.org/10.1038/emi.2017.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750456PMC
December 2017

Using MOEA with Redistribution and Consensus Branches to Infer Phylogenies.

Int J Mol Sci 2017 Dec 26;19(1). Epub 2017 Dec 26.

National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiamen 361102, China.

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http://dx.doi.org/10.3390/ijms19010062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796012PMC
December 2017

Expanded strain coverage for a highly successful public health tool: Prophylactic 9-valent human papillomavirus vaccine.

Hum Vaccin Immunother 2017 10;13(10):2280-2291

a State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics , National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, Xiamen University , Xiamen , Fujian , PR China.

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http://dx.doi.org/10.1080/21645515.2017.1346755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647960PMC
October 2017

A SCID mouse-human lung xenograft model of varicella-zoster virus infection.

Antiviral Res 2017 Oct 18;146:45-53. Epub 2017 Aug 18.

Department of Microbiology and Molecular Genetics, New Jersey Medical School, Rutgers University, 225 Warren Street, Newark, NJ 070101, USA. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2017.08.012DOI Listing
October 2017

A multimechanistic antibody targeting the receptor binding site potently cross-protects against influenza B viruses.

Sci Transl Med 2017 Oct;9(412)

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.

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http://dx.doi.org/10.1126/scitranslmed.aam5752DOI Listing
October 2017

Varicella-zoster virus ORF7 interacts with ORF53 and plays a role in its trans-Golgi network localization.

Virol Sin 2017 Oct 30;32(5):387-395. Epub 2017 Oct 30.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1007/s12250-017-4048-xDOI Listing
October 2017

Calcium phosphate nanoparticles as a new generation vaccine adjuvant.

Expert Rev Vaccines 2017 09 25;16(9):895-906. Epub 2017 Jul 25.

a State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases , Xiamen University , Xiamen , PR China.

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http://dx.doi.org/10.1080/14760584.2017.1355733DOI Listing
September 2017

Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody.

Nat Commun 2017 09 11;8(1):505. Epub 2017 Sep 11.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, PR China.

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http://dx.doi.org/10.1038/s41467-017-00477-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593947PMC
September 2017

Exploring a common mechanism of alcohol-induced deregulation of RNA Pol III genes in liver and breast cells.

Gene 2017 Aug 25;626:309-318. Epub 2017 May 25.

Department of Pharmacology, Shantou University Medical College, China; Cancer Center of Guangzhou Medical University, China; Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2017.05.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521807PMC
August 2017

Severe hand, foot and mouth disease associated with Coxsackievirus A10 infections in Xiamen, China in 2015.

J Clin Virol 2017 08 11;93:20-24. Epub 2017 May 11.

National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiang'an Campus of Xiamen University, South Xiang'an Rd., Xiamen, China; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Xiamen University, Xiang'an Campus of Xiamen University, South Xiang'an Rd., Xiamen, China; School of Public Health, Xiamen University, Xiang'an Campus of Xiamen University, South Xiang'an Rd., Xiamen, China. Electronic address:

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http://dx.doi.org/10.1016/j.jcv.2017.05.011DOI Listing
August 2017

A neonatal mouse model of coxsackievirus A10 infection for anti-viral evaluation.

Antiviral Res 2017 08 15;144:247-255. Epub 2017 Jun 15.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.1016/j.antiviral.2017.06.008DOI Listing
August 2017

Characterization of an Escherichia coli-derived human papillomavirus type 16 and 18 bivalent vaccine.

Vaccine 2017 08 20;35(35 Pt B):4637-4645. Epub 2017 Jul 20.

National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Life Sciences, Xiamen University, Xiamen 361102, China; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.06.084DOI Listing
August 2017

Detection of HBV Covalently Closed Circular DNA.

Viruses 2017 06 6;9(6). Epub 2017 Jun 6.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.

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http://dx.doi.org/10.3390/v9060139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490816PMC
June 2017

Stop codon mutagenesis for homogenous expression of human papillomavirus L1 protein in Escherichia coli.

Protein Expr Purif 2017 05 4;133:110-120. Epub 2017 Mar 4.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, China; National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Life Sciences, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1016/j.pep.2017.03.003DOI Listing
May 2017

A novel combined vaccine based on monochimeric VLP co-displaying multiple conserved epitopes against enterovirus 71 and varicella-zoster virus.

Vaccine 2017 05 10;35(20):2728-2735. Epub 2017 Apr 10.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.1016/j.vaccine.2017.03.065DOI Listing
May 2017

Bacterially expressed human papillomavirus type 6 and 11 bivalent vaccine: Characterization, antigenicity and immunogenicity.

Vaccine 2017 05 5;35(24):3222-3231. Epub 2017 May 5.

National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Life Sciences, Xiamen University, Xiamen 361102, China; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.04.064DOI Listing
May 2017

A Smartphone-Based Genotyping Method for Hepatitis B Virus at Point-of-Care Settings.

SLAS Technol 2017 04 13;22(2):122-129. Epub 2016 Dec 13.

1 Institute of Microfluidic Chip Development in Biomedical Engineering, College of Information Science and Technology, Beijing University of Chemical Technology, Beijing, China.

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http://dx.doi.org/10.1177/2211068216680163DOI Listing
April 2017

Characterization and analysis of real-time capillary convective PCR toward commercialization.

Biomicrofluidics 2017 Mar 3;11(2):024103. Epub 2017 Mar 3.

Department of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1063/1.4977841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533481PMC
March 2017

derived virus-like particles in vaccine development.

NPJ Vaccines 2017 9;2. Epub 2017 Feb 9.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiamen, Fujian 361102 PR China.

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http://dx.doi.org/10.1038/s41541-017-0006-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627247PMC
February 2017

A novel inactivated enterovirus 71 vaccine can elicit cross-protective immunity against coxsackievirus A16 in mice.

Vaccine 2016 11 19;34(48):5938-5945. Epub 2016 Oct 19.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Science & School of Public Health, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.1016/j.vaccine.2016.10.018DOI Listing
November 2016

The 2016 Lasker-DeBakey Clinical Medical Research Award: Innovative hepatitis C virus (HCV) replicons leading to drug development for hepatitis C cure.

Sci China Life Sci 2016 Nov 26;59(11):1198-1201. Epub 2016 Oct 26.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1007/s11427-016-0313-9DOI Listing
November 2016

Real-time stability of a hepatitis E vaccine (Hecolin®) demonstrated with potency assays and multifaceted physicochemical methods.

Vaccine 2016 11 25;34(48):5871-5877. Epub 2016 Oct 25.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiamen, Fujian 361005, PR China; School of Public Health, Xiamen University, Xiamen, Fujian 361005, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2016.10.045DOI Listing
November 2016

An HBV-tolerant immunocompetent model that effectively simulates chronic hepatitis B virus infection in mice.

Exp Anim 2016 Nov 6;65(4):373-382. Epub 2016 Jun 6.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, Xiamen University, Xiamen, 361102, P.R. China.

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http://dx.doi.org/10.1538/expanim.16-0013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111840PMC
November 2016

Antiviral Therapy by HIV-1 Broadly Neutralizing and Inhibitory Antibodies.

Int J Mol Sci 2016 Nov 18;17(11). Epub 2016 Nov 18.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.

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http://dx.doi.org/10.3390/ijms17111901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133900PMC
November 2016

Human papillomavirus prevalence and associated factors in women and men in south China: a population-based study.

Emerg Microbes Infect 2016 Nov 23;5(11):e119. Epub 2016 Nov 23.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.

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http://dx.doi.org/10.1038/emi.2016.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148022PMC
November 2016