Ning Ou

Ning Ou

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Ning Ou

Publications by authors named "Ning Ou"

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Efficacy, safety and pharmacokinetics of ilaprazole infusion in healthy subjects and patients with esomeprazole as positive control.

Br J Clin Pharmacol 2019 Jul 23. Epub 2019 Jul 23.

Livzon Pharmaceutical Group Inc, Zhuhai, 519020, Guangdong, China.

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http://dx.doi.org/10.1111/bcp.14076DOI Listing
July 2019

Effects of CYP3A4*1G and CYP3A5*3 polymorphisms on pharmacokinetics of tylerdipine hydrochloride in healthy Chinese subjects.

Xenobiotica 2019 Mar 28;49(3):375-380. Epub 2018 Mar 28.

b Key Laboratory of Drug Metabolism and Pharmacokinetics , China Pharmaceutical University , Nanjing , China.

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http://dx.doi.org/10.1080/00498254.2018.1447711DOI Listing
March 2019

Mechanism of Lycium barbarum polysaccharides liposomes on activating murine dendritic cells.

Carbohydr Polym 2019 Feb 25;205:540-549. Epub 2018 Oct 25.

Institute of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01448617183124
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http://dx.doi.org/10.1016/j.carbpol.2018.10.057DOI Listing
February 2019

A Randomized, Open-Label, Crossover Phase 1 Study to Evaluate the Effects of Food on the Pharmacokinetics of a Single Oral Dose of a 15-mg Tylerdipine Tablet in Healthy Chinese Male Volunteers.

Clin Pharmacol Drug Dev 2019 Jan 10;8(1):126-132. Epub 2018 Oct 10.

Phase 1 Clinical Trial Unit, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

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http://doi.wiley.com/10.1002/cpdd.622
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http://dx.doi.org/10.1002/cpdd.622DOI Listing
January 2019

Pharmacokinetics, Safety and Tolerability of Tylerdipine Hydrochloride, a Novel Dihydropyridine Dual L/T-type Calcium Channel Blocker, after Single and Multiple Oral Doses in Healthy Chinese Subjects.

Clin Drug Investig 2019 Jan;39(1):85-96

Phase I Clinical Trial Unit, The First Affiliated Hospital with Nanjing Medical University, #300 Guangzhou Road, Nanjing, 210029, Jiangsu, China.

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http://link.springer.com/10.1007/s40261-018-0722-5
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http://dx.doi.org/10.1007/s40261-018-0722-5DOI Listing
January 2019

Angelica sinensis polysaccharide encapsulated into PLGA nanoparticles as a vaccine delivery and adjuvant system for ovalbumin to promote immune responses.

Int J Pharm 2019 Jan 3;554:72-80. Epub 2018 Nov 3.

Institute of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03785173183082
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http://dx.doi.org/10.1016/j.ijpharm.2018.11.008DOI Listing
January 2019

Immunopotentiation of Polysaccharides of Atractylodes macrocephala Koidz-loaded nanostructured lipid carriers as an adjuvant.

Int J Biol Macromol 2018 Dec 23;120(Pt A):768-774. Epub 2018 Aug 23.

Institute of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01418130183333
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http://dx.doi.org/10.1016/j.ijbiomac.2018.08.108DOI Listing
December 2018

Development and validation of two LC-MS/MS methods to assay urinary tylerdipine hydrochloride and its metabolites in healthy Chinese subjects.

J Chromatogr B Analyt Technol Biomed Life Sci 2018 Oct 21;1096:172-179. Epub 2018 Aug 21.

Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15700232173221
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http://dx.doi.org/10.1016/j.jchromb.2018.08.017DOI Listing
October 2018

Evaluation of optimum conditions for Achyranthes bidentata polysaccharides encapsulated in cubosomes and immunological activity in vitro.

Int J Biol Macromol 2018 Apr 20;109:748-760. Epub 2017 Nov 20.

Institute of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ijbiomac.2017.11.064DOI Listing
April 2018

Simple nanoliposomes encapsulating polysaccharides as adjuvants improve humoral and cellular immunity in mice.

Int J Nanomedicine 2017 28;12:6289-6301. Epub 2017 Aug 28.

Institute of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing.

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https://www.dovepress.com/simple-nanoliposomes-encapsulating
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http://dx.doi.org/10.2147/IJN.S136820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584898PMC
March 2018

Optimization of angelica sinensis polysaccharide-loaded Poly (lactic-co-glycolicacid) nanoparticles by RSM and its immunological activity in vitro.

Int J Biol Macromol 2018 Feb 1;107(Pt A):222-229. Epub 2017 Sep 1.

Institute of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01418130173332
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http://dx.doi.org/10.1016/j.ijbiomac.2017.08.176DOI Listing
February 2018

A phase I study to investigate the metabolism, excretion, and pharmacokinetics of [C]fruquintinib, a novel oral selective VEGFR inhibitor, in healthy Chinese male volunteers.

Cancer Chemother Pharmacol 2017 Sep 20;80(3):563-573. Epub 2017 Jul 20.

Phase I Clinical Trial Unit, The First Affiliated Hospital with Nanjing Medical University, #300 Guangzhou Road, Nanjing, 210029, Jiangsu, China.

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http://dx.doi.org/10.1007/s00280-017-3394-6DOI Listing
September 2017

Pharmacokinetics of ginkgolides A, B and K after single and multiple intravenous infusions and their interactions with midazolam in healthy Chinese male subjects.

Eur J Clin Pharmacol 2017 May 20;73(5):537-546. Epub 2017 Jan 20.

State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Jiangsu Kanion Pharmaceutical CO. LTD, Lianyungang, Jiangsu, 222001, China.

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http://dx.doi.org/10.1007/s00228-017-2197-3DOI Listing
May 2017

Pharmacokinetics and pharmacodynamics of intravenous ilaprazole in healthy subjects after single ascending doses.

Xenobiotica 2016 Dec 21;46(12):1133-1141. Epub 2016 Mar 21.

a Clinical Pharmacology Research Center, Peking Union Medical College Hospital , Beijing , China and.

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http://dx.doi.org/10.3109/00498254.2016.1156185DOI Listing
December 2016

Pharmacokinetics, Pharmacodynamics and Safety of Multiple-Infusion Ilaprazole in Healthy Chinese Subjects.

Clin Drug Investig 2016 Jun;36(6):463-70

Clinical Pharmacology Research Center, Peking Union Medical College Hospital, No. 1 Shuaifuyuan, Dongcheng District, Beijing, 100730, China.

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http://dx.doi.org/10.1007/s40261-016-0390-2DOI Listing
June 2016

In Vitro and In Vivo Studies of a New Class of Anticancer Molecules for Targeted Radiotherapy of Cancer.

Mol Cancer Ther 2016 04 26;15(4):640-50. Epub 2016 Feb 26.

Department of Physics and Astronomy, University of Waterloo, Waterloo, Ontario, Canada. Departments of Biology and Chemistry, University of Waterloo, Waterloo, Ontario, Canada.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0862DOI Listing
April 2016

In Vitro and In Vivo Studies of Non-Platinum-Based Halogenated Compounds as Potent Antitumor Agents for Natural Targeted Chemotherapy of Cancers.

EBioMedicine 2015 Jun 20;2(6):544-53. Epub 2015 Apr 20.

Department of Physics and Astronomy, University of Waterloo, 200 University Avenue West, Waterloo, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ebiom.2015.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551467PMC
June 2015

A simple LC-MS/MS method for determination of sitafloxacin in human urine.

J Chromatogr B Analyt Technol Biomed Life Sci 2014 Sep 1;967:219-24. Epub 2014 Aug 1.

Department of Pharmacy, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2014.07.015DOI Listing
September 2014

Antioxidant induces DNA damage, cell death and mutagenicity in human lung and skin normal cells.

Sci Rep 2013 Nov 8;3:3169. Epub 2013 Nov 8.

Department of Physics and Astronomy and Departments of Biology and Chemistry, University of Waterloo, 200 University Avenue West, Waterloo, Ontario, Canada N2L 3G1.

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http://www.nature.com/articles/srep03169
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http://dx.doi.org/10.1038/srep03169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821017PMC
November 2013

Simultaneous quantification of metronidazole, tinidazole, ornidazole and morinidazole in human saliva.

J Chromatogr B Analyt Technol Biomed Life Sci 2012 Jun 15;899:27-30. Epub 2012 May 15.

Research Division of Clinical Pharmacology, The First Affiliated Hospital, Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu 210029, China.

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http://dx.doi.org/10.1016/j.jchromb.2012.04.032DOI Listing
June 2012

Safety and tolerability of bismuthyl ecabet suspension, a novel anti-ulcer agent, following single and multiple oral dose administration in healthy Chinese subjects.

Clin Drug Investig 2012 Apr;32(4):247-52

Research Division of Clinical Pharmacology, the First Affiliated Hospital, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.2165/11599110-000000000-00000DOI Listing
April 2012

Determination of palonosetron in human urine by LC-MS/MS.

Bioanalysis 2011 Jun;3(12):1337-42

Department of Pharmacy, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.

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http://www.future-science.com/doi/10.4155/bio.11.110
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http://dx.doi.org/10.4155/bio.11.110DOI Listing
June 2011

Influence of CYP2C19 on the relationship between pharmacokinetics and intragastric pH of omeprazole administered by successive intravenous infusions in Chinese healthy volunteers.

Eur J Clin Pharmacol 2010 Jun 23;66(6):563-9. Epub 2010 Apr 23.

Research Division of Clinical Pharmacology, The First Affiliated Hospital, Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.

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http://link.springer.com/content/pdf/10.1007/s00228-010-0821
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http://link.springer.com/10.1007/s00228-010-0821-6
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http://dx.doi.org/10.1007/s00228-010-0821-6DOI Listing
June 2010

A validated LC-MS/MS method for determination of sertaconazole nitrate in human plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2009 Dec 15;877(31):4047-50. Epub 2009 Oct 15.

Department of Pharmacy, The First Affiliated Hospital with Nanjing Medical University, China.

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http://dx.doi.org/10.1016/j.jchromb.2009.09.032DOI Listing
December 2009

Inflammatory mediators in Chinese patients with congestive heart failure.

J Clin Pharmacol 2009 May;49(5):591-9

Research Division of Clinical Pharmacology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1177/0091270009333265DOI Listing
May 2009

[An analysis of 276 cases of drug-induced liver damage].

Zhonghua Gan Zang Bing Za Zhi 2006 Nov;14(11):832-4

Department of Infectious Diseases, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.

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November 2006