Nils Brose

Nils Brose

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Nils Brose

Publications by authors named "Nils Brose"

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SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse.

Neuron 2019 07 3;103(2):217-234.e4. Epub 2019 Jun 3.

Department of Functional Genomics, CNCR, VU University and UMC Amsterdam, 1081 HV Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764089PMC
July 2019

Acute Complexin Knockout Abates Spontaneous and Evoked Transmitter Release.

Cell Rep 2019 03;26(10):2521-2530.e5

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany; DFG-Research Center for Nanoscale Microscopy and Molecular Physiology of the Brain, 37073 Göttingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.02.030DOI Listing
March 2019

Dynamically Primed Synaptic Vesicle States: Key to Understand Synaptic Short-Term Plasticity.

Neuron 2018 12;100(6):1283-1291

Department of Molecular Neurobiology, Max Planck Institute for Experimental Medicine, Hermann-Rein-Straße 3, D-37075 Göttingen, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S08966273183101
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http://dx.doi.org/10.1016/j.neuron.2018.11.024DOI Listing
December 2018

Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex.

Cereb Cortex 2018 08;28(8):2873-2886

Institute of Physiology, University Medical Center of the Johannes Gutenberg University Mainz, Duesbergweg 6, Mainz, Germany.

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http://dx.doi.org/10.1093/cercor/bhx165DOI Listing
August 2018

Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.

J Exp Med 2018 06 3;215(6):1543-1553. Epub 2018 May 3.

Department of Molecular and Cellular Physiology and Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA.

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http://www.jem.org/lookup/doi/10.1084/jem.20172162
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http://dx.doi.org/10.1084/jem.20172162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987923PMC
June 2018

Deletion of in adult mice impairs basal AMPA receptor transmission and LTP in hippocampal CA1 pyramidal neurons.

Proc Natl Acad Sci U S A 2018 06 21;115(23):E5382-E5389. Epub 2018 May 21.

Nancy Pritzker Laboratory, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1803280115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003336PMC
June 2018

BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology.

Acta Neuropathol 2018 05 11;135(5):695-710. Epub 2018 Jan 11.

German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen Str. 17, 81377, Munich, Germany.

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http://dx.doi.org/10.1007/s00401-017-1804-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904228PMC
May 2018

Response: Commentary: Analysis of SUMO1-conjugation at synapses.

Front Cell Neurosci 2018 1;12:117. Epub 2018 May 1.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Göttingen, Germany.

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http://dx.doi.org/10.3389/fncel.2018.00117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938361PMC
May 2018

Systematic Localization and Identification of SUMOylation Substrates in Knock-In Mice Expressing Affinity-Tagged SUMO1.

Methods Mol Biol 2016 ;1475:291-301

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Hermann-Rein-Straße 3, 37075, Göttingen, Germany.

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http://dx.doi.org/10.1007/978-1-4939-6358-4_20DOI Listing
January 2018

Building Bridges through Science.

Authors:
Thomas Lissek Michelle Adams John Adelman Ehud Ahissar Mohammed Akaaboune Huda Akil Mustafa al'Absi Fazal Arain Juan Carlos Arango-Lasprilla Deniz Atasoy Jesus Avila Ashraf Badawi Hilmar Bading Abdul Mannan Baig Jimena Baleriola Carlos Belmonte Ilaria Bertocchi Heinrich Betz Colin Blakemore Olaf Blanke Philipp Boehm-Sturm Tobias Bonhoeffer Paolo Bonifazi Nils Brose Patrizia Campolongo Tansu Celikel Cathy C Chang Ta-Yuan Chang Ami Citri Hollis T Cline Jesus M Cortes Kathleen Cullen Kellie Dean José M Delgado-Garcia Mathieu Desroches John F Disterhoft John E Dowling Andreas Draguhn Sherif F El-Khamisy Abdeljabbar El Manira S Ather Enam Juan M Encinas Asier Erramuzpe José A Esteban Isabel Fariñas Edmond Fischer Izumi Fukunaga Iñigo Gabilondo Detlev Ganten Albert Gidon Juan Carlos Gomez-Esteban Paul Greengard Valery Grinevich Agnés Gruart Roger Guillemin Ahmad R Hariri Bassem Hassan Michael Häusser Yasunori Hayashi Natasha K Hussain Adnan Abdul Jabbar Mohamed Jaber Reinhardt Jahn Essam Mohammed Janahi Mohamed Kabbaj Helmut Kettenmann Merel Kindt Shira Knafo Georg Köhr Shoji Komai Harm Krugers Bernd Kuhn Nouria Lakhdar Ghazal Matthew E Larkum Mickey London Beat Lutz Carlos Matute Luis Martinez-Millan Mouna Maroun James McGaugh Ahmed A Moustafa Anwar Nasim Klaus-Armin Nave Erwin Neher Karoly Nikolich Tiago Outeiro Lucy M Palmer Olga Penagarikano Isabel Perez-Otano Donald W Pfaff Bruno Poucet Atta-Ur Rahman Pedro Ramos-Cabrer Ali Rashidy-Pour Richard J Roberts Serafim Rodrigues Joshua R Sanes Andreas T Schaefer Menahem Segal Idan Segev Saad Shafqat Nikhat Ahmed Siddiqui Hermona Soreq Eduardo Soriano-García Rainer Spanagel Rolf Sprengel Greg Stuart Thomas C Südhof Jan Tønnesen Mario Treviño Basim M Uthman J Craig Venter Alexei Verkhratsky Craig Weiss Torsten N Wiesel Emre Yaksi Ofer Yizhar Larry J Young Paul Young Nasser H Zawia José L Zugaza Mazahir T Hasan

Neuron 2017 Nov;96(4):730-735

Achucarro Basque Center for Neuroscience, 48940 Leioa, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.09.028DOI Listing
November 2017

Organizers of inhibitory synapses come of age.

Curr Opin Neurobiol 2017 08 28;45:66-77. Epub 2017 Apr 28.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Hermann-Rein-Straße 3, 37075 Göttingen, Germany.

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http://dx.doi.org/10.1016/j.conb.2017.04.003DOI Listing
August 2017

Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.

Neuron 2017 Aug;95(3):591-607.e10

Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305, USA; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA; Department of Structural Biology, Stanford University, Stanford, CA 94305, USA; Department of Photon Science, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747255PMC
August 2017

Analysis of SUMO1-conjugation at synapses.

Elife 2017 06 9;6. Epub 2017 Jun 9.

Max Planck Institute of Experimental Medicine, Molecular Neurobiology, Göttingen, Germany.

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http://dx.doi.org/10.7554/eLife.26338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493437PMC
June 2017

Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release.

Neuron 2017 Apr;94(2):304-311.e4

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.03.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418202PMC
April 2017

Synapse biology in the 'circuit-age'-paths toward molecular connectomics.

Curr Opin Neurobiol 2017 02 26;42:102-110. Epub 2016 Dec 26.

VIB Center for Brain and Disease Research, Herestraat 49, 3000 Leuven, Belgium; Department of Neurosciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.conb.2016.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316339PMC
February 2017

Endosomal Phosphatidylinositol 3-Phosphate Promotes Gephyrin Clustering and GABAergic Neurotransmission at Inhibitory Postsynapses.

J Biol Chem 2017 01 9;292(4):1160-1177. Epub 2016 Dec 9.

the Department of Neurochemistry, Max Planck Institute for Brain Research, Deutschordenstrasse 46, 60528 Frankfurt am Main, Germany, and.

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http://dx.doi.org/10.1074/jbc.M116.771592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270463PMC
January 2017

Photoswitchable diacylglycerols enable optical control of protein kinase C.

Nat Chem Biol 2016 09 25;12(9):755-62. Epub 2016 Jul 25.

Department of Chemistry and Center for Integrated Protein Science, Ludwig Maximilians University Munich, Munich, Germany.

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http://dx.doi.org/10.1038/nchembio.2141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101201PMC
September 2016

Functional Roles of Complexin 3 and Complexin 4 at Mouse Photoreceptor Ribbon Synapses.

J Neurosci 2016 06;36(25):6651-67

Department of Biology, Animal Physiology, Friedrich Alexander University Erlangen-Nürnberg, 91058 Erlangen, Germany, and

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http://dx.doi.org/10.1523/JNEUROSCI.4335-15.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601749PMC
June 2016

Cognitive Deficits in Calsyntenin-2-deficient Mice Associated with Reduced GABAergic Transmission.

Neuropsychopharmacology 2016 Feb 14;41(3):802-10. Epub 2015 Jul 14.

Brain Research Centre and Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1038/npp.2015.206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707826PMC
February 2016

Selective expression of a constitutively active erythropoietin receptor in GABAergic neurons alters hippocampal network properties without affecting cognition.

J Neurochem 2016 Feb 7;136(4):698-705. Epub 2016 Jan 7.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Göttingen, Germany.

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http://dx.doi.org/10.1111/jnc.13445DOI Listing
February 2016

Neuroligin 2 deletion alters inhibitory synapse function and anxiety-associated neuronal activation in the amygdala.

Neuropharmacology 2016 Jan 30;100:56-65. Epub 2015 Jun 30.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Hermann-Rein-Str. 3, 37075 Göttingen, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00283908153000
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http://dx.doi.org/10.1016/j.neuropharm.2015.06.016DOI Listing
January 2016

Specificity of Collybistin-Phosphoinositide Interactions: IMPACT OF THE INDIVIDUAL PROTEIN DOMAINS.

J Biol Chem 2016 Jan 6;291(1):244-54. Epub 2015 Nov 6.

From the Institute of Organic and Biomolecular Chemistry, University of Göttingen, Tammannstrasse 2, 37077 Göttingen, Germany,

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http://www.jbc.org/lookup/doi/10.1074/jbc.M115.673400
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http://dx.doi.org/10.1074/jbc.M115.673400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697159PMC
January 2016

Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism.

Cell Rep 2015 Oct 8;13(3):516-523. Epub 2015 Oct 8.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Hermann-Rein-Straße 3, 37075 Göttingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862414PMC
October 2015

Fast cerebellar reflex circuitry requires synaptic vesicle priming by munc13-3.

Cerebellum 2015 Jun;14(3):264-83

Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany.

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http://dx.doi.org/10.1007/s12311-015-0645-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441738PMC
June 2015

Complexin stabilizes newly primed synaptic vesicles and prevents their premature fusion at the mouse calyx of held synapse.

J Neurosci 2015 May;35(21):8272-90

Department of Membrane Biophysics, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany, Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany, and DFG-Research Center for Nanoscale Microscopy and Molecular Physiology of the Brain, 37073 Göttingen, Germany

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http://dx.doi.org/10.1523/JNEUROSCI.4841-14.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605347PMC
May 2015

Lipid binding defects and perturbed synaptogenic activity of a Collybistin R290H mutant that causes epilepsy and intellectual disability.

J Biol Chem 2015 Mar 12;290(13):8256-70. Epub 2015 Feb 12.

From the Department of Molecular Neurobiology, Max Planck Institute for Experimental Medicine, 37075 Göttingen, Germany, and

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http://dx.doi.org/10.1074/jbc.M114.633024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375481PMC
March 2015

Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.

J Cell Sci 2015 Feb 20;128(4):638-44. Epub 2015 Jan 20.

Institute for Auditory Neuroscience and InnerEarLab, Department of Otolaryngology, University Medical Center Göttingen, 37099 Göttingen, Germany Collaborative Research Center 889, University of Göttingen, 37099 Göttingen, Germany Molecular Architecture of Synapses Group, Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37099 Göttingen, Germany

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http://dx.doi.org/10.1242/jcs.162099DOI Listing
February 2015

Secretory vesicle priming by CAPS is independent of its SNARE-binding MUN domain.

Cell Rep 2014 Nov 23;9(3):902-9. Epub 2014 Oct 23.

Institute of Physiology, Saarland University, Building 59, 66421 Homburg/Saar, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.09.050DOI Listing
November 2014

Munc13-3 superprimes synaptic vesicles at granule cell-to-basket cell synapses in the mouse cerebellum.

J Neurosci 2014 Oct;34(44):14687-96

Carl Ludwig Institute for Physiology, Medical Faculty, University of Leipzig, D-04103 Leipzig, Germany, and

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.2060-14.2
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http://dx.doi.org/10.1523/JNEUROSCI.2060-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608426PMC
October 2014

The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones.

Neuron 2014 Oct 22;84(2):416-31. Epub 2014 Oct 22.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2014.10.009DOI Listing
October 2014

Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.

Behav Brain Res 2014 Aug 20;270:159-64. Epub 2014 May 20.

Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany; DFG Center for Nanoscale Microscopy & Molecular Physiology of the Brain (CNMPB), Göttingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2014.05.019DOI Listing
August 2014

Neurobiology of autism gene products: towards pathogenesis and drug targets.

Psychopharmacology (Berl) 2014 Mar 14;231(6):1037-62. Epub 2014 Jan 14.

Department Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Universiteitsweg 100, 3984 CG, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00213-013-3403-3DOI Listing
March 2014

All roads lead to neuroscience: the 2013 Nobel Prize in Physiology or Medicine.

Authors:
Nils Brose

Neuron 2014 Feb;81(4):723-7

Max Planck Institute of Experimental Medicine, Department of Molecular Neurobiology, Hermann-Rein-Straße 3, 37075 Göttingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2014.02.008DOI Listing
February 2014

Collybistin activation by GTP-TC10 enhances postsynaptic gephyrin clustering and hippocampal GABAergic neurotransmission.

Proc Natl Acad Sci U S A 2013 Dec 2;110(51):20795-800. Epub 2013 Dec 2.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1309078110
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http://dx.doi.org/10.1073/pnas.1309078110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870750PMC
December 2013

Nobel 2013 Physiology or medicine: Traffic control system within cells.

Nature 2013 Dec;504(7478):98

Howard Hughes Medical Institute, Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, California 92093-0668, USA.

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http://dx.doi.org/10.1038/504098aDOI Listing
December 2013

An LRRTM4-HSPG complex mediates excitatory synapse development on dentate gyrus granule cells.

Neuron 2013 Aug 1;79(4):680-95. Epub 2013 Aug 1.

Brain Research Centre and Department of Psychiatry, University of British Columbia, Vancouver, BC V6T 2B5, Canada.

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http://dx.doi.org/10.1016/j.neuron.2013.06.029DOI Listing
August 2013

Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling.

Neuron 2013 Jul 13;79(1):82-96. Epub 2013 Jun 13.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.

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http://dx.doi.org/10.1016/j.neuron.2013.05.011DOI Listing
July 2013

Spike bursts increase amyloid-β 40/42 ratio by inducing a presenilin-1 conformational change.

Nat Neurosci 2013 May 7;16(5):587-95. Epub 2013 Apr 7.

Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1038/nn.3376DOI Listing
May 2013

Evidence for a common endocannabinoid-related pathomechanism in autism spectrum disorders.

Neuron 2013 May;78(3):408-10

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.

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http://dx.doi.org/10.1016/j.neuron.2013.04.030DOI Listing
May 2013

Why we need more synaptogenic cell-adhesion proteins.

Authors:
Nils Brose

Proc Natl Acad Sci U S A 2013 Mar 20;110(10):3717-8. Epub 2013 Feb 20.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.

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http://dx.doi.org/10.1073/pnas.1300505110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593840PMC
March 2013

Neurobeachin regulates neurotransmitter receptor trafficking to synapses.

J Cell Biol 2013 Jan 31;200(1):61-80. Epub 2012 Dec 31.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.

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http://dx.doi.org/10.1083/jcb.201207113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542797PMC
January 2013

In vivo localization and identification of SUMOylated proteins in the brain of His6-HA-SUMO1 knock-in mice.

Proc Natl Acad Sci U S A 2012 Dec 3;109(51):21122-7. Epub 2012 Dec 3.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.

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http://dx.doi.org/10.1073/pnas.1215366110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529052PMC
December 2012

Structural plasticity of spines at giant mossy fiber synapses.

Front Neural Circuits 2012 18;6:103. Epub 2012 Dec 18.

Center for Molecular Neurobiology Hamburg, Institute for Structural Neurobiology Hamburg, Germany.

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http://dx.doi.org/10.3389/fncir.2012.00103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524460PMC
December 2012

Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.

Mol Cell Biol 2012 Nov 10;32(22):4628-41. Epub 2012 Sep 10.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Göttingen, Germany.

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http://dx.doi.org/10.1128/MCB.00933-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486184PMC
November 2012

Homodimerization and isoform-specific heterodimerization of neuroligins.

Biochem J 2012 Sep;446(2):321-30

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, and DFG Center for the Molecular Physiology of the Brain, D-37075 Göttingen, Germany.

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http://dx.doi.org/10.1042/BJ20120808DOI Listing
September 2012

Structural plasticity of hippocampal mossy fiber synapses as revealed by high-pressure freezing.

J Comp Neurol 2012 Aug;520(11):2340-51

Department for Structural Neurobiology, Center for Molecular Neurobiology Hamburg-ZMNH, University of Hamburg, D-20246 Hamburg, Germany.

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http://dx.doi.org/10.1002/cne.23040DOI Listing
August 2012

The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses.

Curr Opin Neurobiol 2012 Jun 15;22(3):412-22. Epub 2012 Mar 15.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Hermann-Rein-Straße 3, 37075 Göttingen, Germany.

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http://dx.doi.org/10.1016/j.conb.2012.02.012DOI Listing
June 2012

Analysis of neurotransmitter release mechanisms by photolysis of caged Ca²⁺ in an autaptic neuron culture system.

Nat Protoc 2012 Jun 21;7(7):1351-65. Epub 2012 Jun 21.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Göttingen, Germany.

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http://dx.doi.org/10.1038/nprot.2012.074DOI Listing
June 2012

The RacGAP β2-Chimaerin selectively mediates axonal pruning in the hippocampus.

Cell 2012 Jun;149(7):1594-606

The Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.cell.2012.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395473PMC
June 2012

CaMKII binding to GluN2B is critical during memory consolidation.

EMBO J 2012 Mar 10;31(5):1203-16. Epub 2012 Jan 10.

Department of Pharmacology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.

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http://dx.doi.org/10.1038/emboj.2011.482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297991PMC
March 2012

The cytoskeletal adapter protein 4.1G organizes the internodes in peripheral myelinated nerves.

J Cell Biol 2012 Feb 30;196(3):337-44. Epub 2012 Jan 30.

Department of Molecular Neurobiology and 2 Department of Neurogenetics, Max Planck Institute of Experimental Medicine, D-37075 Göttingen, Germany.

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http://dx.doi.org/10.1083/jcb.201111127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275379PMC
February 2012

The role of ubiquitylation in nerve cell development.

Nat Rev Neurosci 2011 May;12(5):251-68

Max Planck Institute of Experimental Medicine, Department of Molecular Neurobiology, Hermann-Rein Straße 3, D-37075 Göttingen, Germany. de

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http://dx.doi.org/10.1038/nrn3009DOI Listing
May 2011

Exocytosis at the hair cell ribbon synapse apparently operates without neuronal SNARE proteins.

Nat Neurosci 2011 Apr 6;14(4):411-3. Epub 2011 Mar 6.

InnerEarLab, Department of Otolaryngology and Center for Molecular Physiology of the Brain, University of Göttingen Medical Center, Göttingen, Germany.

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http://dx.doi.org/10.1038/nn.2774DOI Listing
April 2011

Increased dentate gyrus excitability in neuroligin-2-deficient mice in vivo.

Cereb Cortex 2011 Feb 7;21(2):357-67. Epub 2010 Jun 7.

Institute of Clinical Neuroanatomy, Goethe-University Frankfurt, NeuroScience Center, D-60590 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1093/cercor/bhq100DOI Listing
February 2011

Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina.

Proc Natl Acad Sci U S A 2011 Feb 31;108(7):3053-8. Epub 2011 Jan 31.

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, D-37075 Göttingen, Germany.

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http://dx.doi.org/10.1073/pnas.1006946108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041141PMC
February 2011

Deletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like disease.

Proc Natl Acad Sci U S A 2011 Feb 7;108(8):3216-21. Epub 2011 Feb 7.

Departments of Biochemistry and Physiology, The Hospital for Sick Children, Programs in Cell Biology and Neuroscience and Mental Health, and University of Toronto, Toronto, ON, Canada M5G 1X8.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044364PMC
February 2011

SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming.

Neuron 2010 Nov;68(3):473-87

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, D-37075 Göttingen, Germany.

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http://dx.doi.org/10.1016/j.neuron.2010.09.019DOI Listing
November 2010

The ubiquitin E3 ligase Nedd4-1 controls neurite development.

Cell Cycle 2010 Jul;9(13):2477-8

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http://dx.doi.org/10.4161/cc.9.13.12236DOI Listing
July 2010

Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells.

Nat Neurosci 2010 Jul 20;13(7):869-76. Epub 2010 Jun 20.

InnerEarLab, Department of Otolaryngology and Center for Molecular Physiology of the Brain, University Medical Center Göttingen, Göttingen, Germany.

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http://dx.doi.org/10.1038/nn.2578DOI Listing
July 2010

1H, 13C and 15N resonance assignments of the Calmodulin-Munc13-1 peptide complex.

Biomol NMR Assign 2010 Apr 15;4(1):45-8. Epub 2009 Dec 15.

NMR-Based Structural Biology Department, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.

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http://dx.doi.org/10.1007/s12104-009-9204-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862173PMC
April 2010

Synaptopathy: dysfunction of synaptic function?

Biochem Soc Trans 2010 Apr;38(2):443-4

Department of Molecular Neurobiology, Max Planck Institute for Experimental Medicine, Hermann-Rein-Strasse 3, 37077 Göttingen Germany.

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http://dx.doi.org/10.1042/BST0380443DOI Listing
April 2010

Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis.

Nat Struct Mol Biol 2010 Mar 14;17(3):280-8. Epub 2010 Feb 14.

Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1038/nsmb.1758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916016PMC
March 2010

The ubiquitin ligase Nedd4-1 is required for heart development and is a suppressor of thrombospondin-1.

J Biol Chem 2010 Feb 21;285(9):6770-80. Epub 2009 Dec 21.

Program in Cell Biology and the Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada.

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http://dx.doi.org/10.1074/jbc.M109.082347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825471PMC
February 2010

Flowers for synaptic endocytosis.

Cell 2009 Sep;138(5):836-7

Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, D-37075 Göttingen, Germany.

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http://dx.doi.org/10.1016/j.cell.2009.08.023DOI Listing
September 2009