Publications by authors named "Niladri Banerjee"

21 Publications

  • Page 1 of 1

Post-COVID-19 Intestinal and Mesenteric Mucormycosis.

Am Surg 2021 Nov 3:31348211048841. Epub 2021 Nov 3.

Department of Diagnostic and Interventional Radiology, 410730All India Institute of Medical Sciences, Jodhpur, India.

A thirty-eight-year-old uncontrolled diabetic with a recent COVID-19 infection presented with extensive bowel ischemia and gangrene with a microscopic diagnosis of intestinal and mesenteric mucormycosis. Although there are a few reported cases of primary gastrointestinal mucormycosis, our case showing involvement of the intestine and/or mesentery, that too in a post-COVID patient, is quite uncommon. The immunosuppressive effect of the COVID-19 disease, uncontrolled diabetes, and the use of corticosteroids for the treatment of severe COVID are the most probable reasons for the emergence of severe opportunistic infections, both as a coinfection and as a sequalae to COVID.
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http://dx.doi.org/10.1177/00031348211048841DOI Listing
November 2021

Superconductivity assisted change of the perpendicular magnetic anisotropy in V/MgO/Fe junctions.

Sci Rep 2021 Sep 24;11(1):19041. Epub 2021 Sep 24.

Departamento Física de la Materia Condensada C-III, Instituto Nicolás Cabrera (INC) and Condensed Matter Physics Institute (IFIMAC), Universidad Autónoma de Madrid, Madrid, 28049, Spain.

Controlling the perpendicular magnetic anisotropy (PMA) in thin films has received considerable attention in recent years due to its technological importance. PMA based devices usually involve heavy-metal (oxide)/ferromagnetic-metal bilayers, where, thanks to interfacial spin-orbit coupling (SOC), the in-plane (IP) stability of the magnetisation is broken. Here we show that in V/MgO/Fe(001) epitaxial junctions with competing in-plane and out-of-plane (OOP) magnetic anisotropies, the SOC mediated interaction between a ferromagnet (FM) and a superconductor (SC) enhances the effective PMA below the superconducting transition. This produces a partial magnetisation reorientation without any applied field for all but the largest junctions, where the IP anisotropy is more robust; for the smallest junctions there is a reduction of the field required to induce a complete OOP transition ([Formula: see text]) due to the stronger competition between the IP and OOP anisotropies. Our results suggest that the degree of effective PMA could be controlled by the junction lateral size in the presence of superconductivity and an applied electric field. We also discuss how the [Formula: see text] field could be affected by the interaction between magnetic stray fields and superconducting vortices. Our experimental findings, supported by numerical modelling of the ferromagnet-superconductor interaction, open pathways to active control of magnetic anisotropy in the emerging dissipation-free superconducting spin electronics.
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http://dx.doi.org/10.1038/s41598-021-98079-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463706PMC
September 2021

An epidemic within a pandemic.

Trop Doct 2021 Aug 30:494755211041876. Epub 2021 Aug 30.

Assistant Professor, Department of Trauma & Emergency, AIIMS, Raebareli, India.

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http://dx.doi.org/10.1177/00494755211041876DOI Listing
August 2021

Identification of pleiotropy at the gene level between psychiatric disorders and related traits.

Transl Psychiatry 2021 07 29;11(1):410. Epub 2021 Jul 29.

NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway.

Major mental disorders are highly prevalent and make a substantial contribution to the global disease burden. It is known that mental disorders share clinical characteristics, and genome-wide association studies (GWASs) have recently provided evidence for shared genetic factors as well. Genetic overlaps are usually identified at the single-marker level. Here, we aimed to identify genetic overlaps at the gene level between 7 mental disorders (schizophrenia, autism spectrum disorder, major depressive disorder, anorexia nervosa, ADHD, bipolar disorder and anxiety), 8 brain morphometric traits, 2 cognitive traits (educational attainment and general cognitive function) and 9 personality traits (subjective well-being, depressive symptoms, neuroticism, extraversion, openness to experience, agreeableness and conscientiousness, children's aggressive behaviour, loneliness) based on publicly available GWASs. We performed systematic conditional regression analyses to identify independent signals and select loci associated with more than one trait. We identified 48 genes containing independent markers associated with several traits (pleiotropy at the gene level). We also report 9 genes with different markers that show independent associations with single traits (allelic heterogeneity). This study demonstrates that mental disorders and related traits do show pleiotropy at the gene level as well as the single-marker level. The identification of these genes might be important for prioritizing further deep genotyping, functional studies, or drug targeting.
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http://dx.doi.org/10.1038/s41398-021-01530-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322263PMC
July 2021

Developmental delay among children under two years of age in slums of Burdwan Municipality: A cross-sectional study.

J Family Med Prim Care 2021 May 31;10(5):1945-1949. Epub 2021 May 31.

Department of Community Medicine, Burdwan Medical College & Hospital, Purba Bardhaman, West Bengal, India.

Context: Development is an ongoing process through which an individual acquires competence to function adequately. Developmental delay is said to occur when a child fails to reach the age-appropriate anticipated milestones. This imparts long-term direct as well as indirect effects on the health of a community obviating routine measurement of its prevalence especially in high-risk populations.

Aim: To find out the prevalence and correlates of developmental delay among children under two years of age in slums of Burdwan Municipality, West Bengal.

Settings And Design: A community-based descriptive cross-sectional study.

Methods And Materials: This study was conducted between September-November 2019 among 240 study subjects selected by multistage simple random sampling. Data were collected by interviewing the respondents using a predesigned, pretested schedule. Developmental status was assessed by applying Trivandrum Developmental Screening Chart (TDSC). Chi-square test and logistic regression was done to find associations.

Results: Prevalence of developmental delay was 6.6%(95%CI 3.6-9.8) and proportion was more among male infants. Chi square test revealed gender ( = 0.03), mothers' education ( = 0.00), socio-economic status ( = 0.00), parity ( = 0.02), birth spacing ( = 0.01) birth weight ( = 0.00) to be significantly associated with developmental delay and multivariable analysis showed all the factors to be significant predictors except gender, parity and birth spacing. Gestational duration, maternal age at delivery, mode of delivery was not found to be significantly associated with developmental delay.

Conclusion: Developmental delay is considerably high in the study area. A larger study using appropriate tool and follow-up may elicit the burden and associated determinants.
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http://dx.doi.org/10.4103/jfmpc.jfmpc_1926_20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208187PMC
May 2021

Contraceptive behavior and unmet need among the tribal married women aged 15-49 years: A cross-sectional study in a community development block of paschim Bardhaman District, West Bengal.

Indian J Public Health 2021 Apr-Jun;65(2):159-165

Assistant Professor, Department of Community Medicine, Burdwan Medical College, Burdwan, West Bengal, India.

Background: Contraceptive behavior and unmet need for family planning, particularly among the tribal women of reproductive age in India, still remains a public health concern. This needs to be explored in different geographical regions.

Objectives: : This study aimed to ascertain the contraceptive behavior of tribal married women of 15-49 years and to assess the unmet need for family planning and its determinants.

Methods: : A descriptive, cross-sectional study was conducted during May 2019 to April 2020 in Barabani Block of Paschim Bardhaman District, West Bengal. A calculated sample of 530 study participants was selected from the study area by the simple random sampling. Required data on contraceptive behavior characteristics, unmet need, and correlates were collected by interviewing them with a predesigned schedule. Bivariate analysis and multivariable logistic regression were done. Data were analyzed using the SPSS software v. 20.

Results: : All study participants were Hindu and belonged to Santhal ethnicity; 53.4% were illiterate; 51.7% had early marriage, and 52.4% had adolescent pregnancy. Only 41.1% women were found currently using any contraceptives, another 14.5% ever used and 44.4% never used any methods. Apprehension of side effects and spouse disapproval were reported as two common reasons for never using contraceptives. The age of the women appeared as a significant predictor of current contraceptive use. Overall, unmet need for family planning was 19.4% and age of the women, socioeconomic status, and type of the family were found as significant predictors.

Conclusion: Issues contributing to unsatisfactory contraceptive behavior and high unmet need for family planning need to be addressed appropriately.
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http://dx.doi.org/10.4103/ijph.IJPH_115_21DOI Listing
October 2021

Status of salt iodization, related awareness and practice at the household level in slums of Burdwan Municipality, West Bengal.

J Family Med Prim Care 2021 Jan 30;10(1):361-366. Epub 2021 Jan 30.

Department of Community Medicine, Burdwan Medical College, West Bengal, India.

Background: Monitoring adequacy of salt iodization at consumption level and exploring the reasons for inadequacy, especially in marginalized communities, is crucial to achieve the target coverage of universal salt iodization.

Aims: To assess the iodine content of salt used at household level, related awareness and practice of respondents and their socio demographic correlates.

Settings And Designs: This cross-sectional descriptive study was conducted in the slums of Burdwan Municipality in 2019.

Methods And Material: A total of 330 households were selected by cluster sampling. Salt iodine content was estimated at household level semi-quantitatively by Iodine testing kit, following recommended guidelines. One respondent from each household was interviewed to assess their awareness and practice regarding iodized salt. Kruskal Wallis test, Mann Whitney U test and Multivariable logistic regression was used.

Results: All 330 households were using iodized salt; 77.6% were consuming adequately iodized and 22.4% were consuming inadequately iodized salts. Only 30.9% of the respondents were aware about the importance of iodized salt, few had correct practice despite inadequate knowledge and none, except one, practiced adding salt at the end of cooking. Awareness and practice were associated with caste and age of the respondents, respectively. Keeping salt container near the oven, adjusting for keeping salt in uncovered container, significantly predicted inadequate level of iodization [AOR 6.17 (95% CI: 2.68-14.26)].

Conclusion: Inadequate iodization, lack of awareness regarding iodized salt and faulty storing practices amounting to increased risk of inadequate iodization are still prevalent emphasizing the need, in policy, for health education.
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http://dx.doi.org/10.4103/jfmpc.jfmpc_1576_20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132837PMC
January 2021

Strain driven emergence of topological non-triviality in YPdBi thin films.

Sci Rep 2021 Apr 6;11(1):7535. Epub 2021 Apr 6.

Department of Physics, Indian Institute of Technology Delhi, New Delhi, India.

Half-Heusler compounds exhibit a remarkable variety of emergent properties such as heavy-fermion behaviour, unconventional superconductivity and magnetism. Several of these compounds have been predicted to host topologically non-trivial electronic structures. Remarkably, recent theoretical studies have indicated the possibility to induce non-trivial topological surface states in an otherwise trivial half-Heusler system by strain engineering. Here, using magneto-transport measurements and first principles DFT-based simulations, we demonstrate topological surface states on strained [110] oriented thin films of YPdBi grown on (100) MgO. These topological surface states arise in an otherwise trivial semi-metal purely driven by strain. Furthermore, we observe the onset of superconductivity in these strained films highlighting the possibility of engineering a topological superconducting state. Our results demonstrate the critical role played by strain in engineering novel topological states in thin film systems for developing next-generation spintronic devices.
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http://dx.doi.org/10.1038/s41598-021-86936-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024271PMC
April 2021

A randomized trial analyzing the effects of primary versus delayed primary closure of incision on wound healing in patients with hollow viscus perforation.

Turk J Surg 2020 Dec 29;36(4):327-332. Epub 2020 Dec 29.

Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.

Objectives: Delayed primary closure (DPC) of the skin has been suggested to decrease superficial surgical site infection (SSSI) in patients undergoing surgery for peritonitis secondary to hollow viscus perforation, but there is no consensus. The aim of this study was to compare the outcomes of primary closure (PC) and DPC of the skin in terms of SSSI, fascial dehiscence and length of hospital stay (LOS).

Material And Methods: Sixty patients, undergoing emergency surgery for perforation peritonitis, were randomized to PC (n= 30) and DPC (n= 30). Patients in the DPC group underwent skin closure four or more days after surgery when the wound was clinically considered appropriate for closure. Patients in the PC group had skin closure at the time of surgery.

Results: Incidence of SSSI was significantly less in the DPC group (7.4%) compared to the PC (42.9%) (p= 0.004). However, the median time of DPC was the 10th POD, i.e., these wounds required considerable time to become clinically suitable for closure. Incidence of fascial dehiscence was comparable between the two groups (p= 0.67). Length of hospital stay (LOS) was 13.8 days in the DPC group compared to 13.5 days in PC; the difference was not significant (p= 0.825).

Conclusion: DPC of the skin incision resulted in the reduction of SSSI. However, this did not translate into a reduction in hospital stay, as it took considerable time for these wounds to become appropriate for DPC, thus bringing into question any real advantage of DPC over PC.
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http://dx.doi.org/10.47717/turkjsurg.2020.4882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963304PMC
December 2020

Trauma care in the times of COVID.

Br J Surg 2020 10 25;107(11):e505. Epub 2020 Aug 25.

Division of Trauma Surgery & Critical Care, Department of Surgical disciplines, AIIMS, New Delhi, India.

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http://dx.doi.org/10.1002/bjs.11967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461182PMC
October 2020

Letter to the Editor: Unstable Hemodynamics is not Always Predictive of Failed Nonoperative Management in Blunt Splenic Injury.

World J Surg 2020 10 9;44(10):3577. Epub 2020 Jul 9.

JPN Apex Trauma Center, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1007/s00268-020-05688-8DOI Listing
October 2020

Train-Associated Injuries Pose a Significant Burden on Trauma Care Systems of Emerging Economies.

World J Surg 2020 09;44(9):2993-2999

Dept. of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.

Background: The Indian railway system is the fourth largest in the world and causes about 15 deaths every day, due to intentional or unintentional reasons. This study presents a 5-year retrospective analysis of patients injured due to train-associated events, managed at a level-1 trauma center in India.

Materials And Methods: Hospital-based trauma registry data of train-associated injuries presenting between 2012 and 2016 were analyzed. Data from 726 patients were analyzed for demographics, injury events, injury regions, their management and outcomes. ISS and NISS were used to quantify the injury severity.

Results: Mean age was 33 years, with male-to-female ratio 86 to 14%. The majority of patients (62%) were between 20-40 years. The median ISS was 9 (IQR 4-16), median hospital stays 11 days (IQR6-23), with in-hospital mortality of 17.4%. Presence of head injury; ISS > 9 and CPR in ED were independent risk factors of mortality. Trespassers on the rail track had significantly more severe injuries compared to passengers (Median ISS 13 vs. 9, p = 0.012; Median NISS 22 vs.17, p = 0.015); however, mortality and hospital length of stay were not significantly different. Location of injury event (on platform or tracks) showed no difference between the severity of injuries, mortality and hospital length of stay.

Conclusions: Current study reports comprehensive injury patterns and outcomes of train-associated injuries from a low- and middle-income country (LMIC). Apart from the mortality, there is a high incidence of permanent disabilities from extremity amputations. No significant difference was noted in the severity and outcomes among patients injured on or off train platforms, emphasizing the need for comprehensive safety measures including enforcement and promoting safe behavior not only on locations like train tracks but equally at platforms.
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http://dx.doi.org/10.1007/s00268-020-05563-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224012PMC
September 2020

Compartment syndrome of the non-injured limb.

BMJ Case Rep 2020 Apr 9;13(4). Epub 2020 Apr 9.

Division of Trauma Surgery and Critical Care, JPN Apex Trauma Centre, All India Institute of Medical Sciences, New Delhi, Delhi, India.

Compartment syndrome is a common limb-threatening entity in trauma. However, the occurrence of the same in the non-injured limb is rare. It seems to be multifactorial in origin, with abnormal positioning being the most common cause. We present such a case of well-leg compartment syndrome which was treated by an urgent fasciotomy. We emphasise on the fact that the diagnosis of compartment syndrome is clinical and the management remains the same irrespective of whether the limb has sustained an injury or not.
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http://dx.doi.org/10.1136/bcr-2019-231657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167449PMC
April 2020

Primary vs delayed primary closure in patients undergoing lower limb amputation following trauma: A randomised control study.

Int Wound J 2020 Apr 20;17(2):419-428. Epub 2019 Dec 20.

Division of Trauma Surgery & Critical Care, JPNATC, AIIMS, New Delhi, India.

Lower limb crush injury is a major source of mortality and morbidity in trauma patients. Complications, especially surgical site infections (SSIs) are a major source of financial burden to the institute and to the patient as it delays rehabilitation. As such, every possible attempt should be made to reduce any complications. We, thus, aimed to compare the outcomes in early vs delayed closure of lower extremity stumps in cases of lower limb crush injury requiring amputation, so as to achieve best possible outcome. A randomised controlled study was conducted in the Division of Trauma Surgery & Critical Care at Jai Prakash Narayan Apex Trauma Centre, All India Institute of Medical Sciences, New Delhi from 1 September 2018 to 30 June 2019 and included patients undergoing lower limb amputation below hip joint. Patients were randomised in two groups, in one group amputation stump was closed primarily, while in the second group delayed primary closure of stump was performed. We compared rate of SSI, length of hospital stay, and number of surgeries in both the groups. Fifty-six patients with 63 amputation stumps were recruited in the study. Mean age of patients in the study was 34 years, of which about 95% patients were males. The most common mechanism of injury was road traffic injury in 66% of patients. Mean injury severity score was 12.28 and four patients had diabetes preoperatively. Total 63 extremities were randomised with 30 cases in group I and 33 cases in group II as per computer-generated random number. Above knee amputations was commonest (57.14%) followed by below knee amputations (33.3%). Two patients died in the current study. In group I, In-hospital infection was detected in 7 cases (23.3%) and in group II 9 cases (27.3%) had SSI during hospital admission (P > .05). Mean hospital stay in group I was 10.32 ± 7.68 days and in group II was 11 ± 8.17 days (P > .05). Road traffic injuries and train-associated injuries are a major cause of lower limb crush injuries, leading to limb loss. Delayed primary closure of such wounds requires extra number of surgical interventions than primary closure. There is no difference in extra number of surgical interventions required in both the groups. Thus, primary closure can be safely performed in patients undergoing lower limb amputations following trauma, provided that a good lavage and wound debridement is performed.
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http://dx.doi.org/10.1111/iwj.13288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948721PMC
April 2020

Post-traumatic bronchobiliary fistula.

BMJ Case Rep 2019 Apr 5;12(4). Epub 2019 Apr 5.

Division of Trauma Surgery and Critical Care, JPN Apex Trauma Centre, All India Institute of Medical Sciences, New Delhi, India.

Post-traumatic bronchobiliary fistula (BBF) is a rare entity, with only a few cases reported worldwide. Bilioptysis is pathognomonic of the condition, however, bronchoscopy and bronchoalveolar lavage along with CT are used for confirmation. We describe this condition in a young woman who presented to us with bilioptysis following a laparotomy for blunt torso trauma. Diagnosis was made of BBF, followed by surgical management and complete recovery. We emphasise the signs of early diagnosis, confirmatory tests, individualised treatment and advocate surgical management as the gold standard of treatment.
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http://dx.doi.org/10.1136/bcr-2018-228294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453415PMC
April 2019

Analysis of differentially methylated regions in great apes and extinct hominids provides support for the evolutionary hypothesis of schizophrenia.

Schizophr Res 2019 04 11;206:209-216. Epub 2018 Dec 11.

NORMENT - K.G. Jebsen Center for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway; Dr. Einar Martens Research Group for Biological Psychiatry, Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway. Electronic address:

Introduction: The persistence of schizophrenia in human populations separated by geography and time led to the evolutionary hypothesis that proposes schizophrenia as a by-product of the higher cognitive abilities of modern humans. To explore this hypothesis, we used here an evolutionary epigenetics approach building on differentially methylated regions (DMRs) of the genome.

Methods: We implemented a polygenic enrichment testing pipeline using the summary statistics of genome-wide association studies (GWAS) of schizophrenia and 12 other phenotypes. We investigated the enrichment of association of these traits across genomic regions with variable methylation between modern humans and great apes (orangutans, chimpanzees and gorillas; great ape DMRs) and between modern humans and recently extinct hominids (Neanderthals and Denisovans; hominid DMRs).

Results: Regions that are hypo-methylated in humans compared to great apes show enrichment of association with schizophrenia only if the major histocompatibility complex (MHC) region is included. With the MHC region removed from the analysis, only a modest enrichment for SNPs of low effect persists. The INRICH pipeline confirms this finding after rigorous permutation and bootstrapping procedures.

Conclusion: The analyses of regions with differential methylation changes in humans and great apes do not provide compelling evidence of enrichment of association with schizophrenia, in contrast to our previous findings on more recent methylation differences between modern humans, Neanderthals and Denisovans. Our results further support the evolutionary hypothesis of schizophrenia and indicate that the origin of some of the genetic susceptibility factors of schizophrenia may lie in recent human evolution.
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http://dx.doi.org/10.1016/j.schres.2018.11.025DOI Listing
April 2019

Recently evolved human-specific methylated regions are enriched in schizophrenia signals.

BMC Evol Biol 2018 05 11;18(1):63. Epub 2018 May 11.

NORMENT - K.G. Jebsen Center for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway.

Background: One explanation for the persistence of schizophrenia despite the reduced fertility of patients is that it is a by-product of recent human evolution. This hypothesis is supported by evidence suggesting that recently-evolved genomic regions in humans are involved in the genetic risk for schizophrenia. Using summary statistics from genome-wide association studies (GWAS) of schizophrenia and 11 other phenotypes, we tested for enrichment of association with GWAS traits in regions that have undergone methylation changes in the human lineage compared to Neanderthals and Denisovans, i.e. human-specific differentially methylated regions (DMRs). We used analytical tools that evaluate polygenic enrichment of a subset of genomic variants against all variants.

Results: Schizophrenia was the only trait in which DMR SNPs showed clear enrichment of association that passed the genome-wide significance threshold. The enrichment was not observed for Neanderthal or Denisovan DMRs. The enrichment seen in human DMRs is comparable to that for genomic regions tagged by Neanderthal Selective Sweep markers, and stronger than that for Human Accelerated Regions. The enrichment survives multiple testing performed through permutation (n = 10,000) and bootstrapping (n = 5000) in INRICH (p < 0.01). Some enrichment of association with height was observed at the gene level.

Conclusions: Regions where DNA methylation modifications have changed during recent human evolution show enrichment of association with schizophrenia and possibly with height. Our study further supports the hypothesis that genetic variants conferring risk of schizophrenia co-occur in genomic regions that have changed as the human species evolved. Since methylation is an epigenetic mark, potentially mediated by environmental changes, our results also suggest that interaction with the environment might have contributed to that association.
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http://dx.doi.org/10.1186/s12862-018-1177-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946405PMC
May 2018

Particle-based optical pressure sensors for 3D pressure mapping.

Biomed Microdevices 2015 Oct;17(5):97

Department of Electrical and Computer Engineering, University of Utah, Salt Lake City, UT, USA,

This paper presents particle-based optical pressure sensors for in-flow pressure sensing, especially for microfluidic environments. Three generations of pressure sensitive particles have been developed- flat planar particles, particles with integrated retroreflectors and spherical microballoon particles. The first two versions suffer from pressure measurement dependence on particles orientation in 3D space and angle of interrogation. The third generation of microspherical particles with spherical symmetry solves these problems making particle-based manometry in microfluidic environment a viable and efficient methodology. Static and dynamic pressure measurements have been performed in liquid medium for long periods of time in a pressure range of atmospheric to 40 psi. Spherical particles with radius of 12 μm and balloon-wall thickness of 0.5 μm are effective for more than 5 h in this pressure range with an error of less than 5%.
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http://dx.doi.org/10.1007/s10544-015-0004-4DOI Listing
October 2015

Plexiform angiomyxoid myofibroblastic tumour of the duodenum: a rare entity.

BMJ Case Rep 2015 Jul 27;2015. Epub 2015 Jul 27.

Department of Surgery, Medical College, Kolkata, Kolkata, West Bengal, India.

Plexiform angiomyxoid myofibroblastic tumour (PAMT) has recently emerged as a new entity among gastrointestinal mesenchymal tumours. All of the 27 cases reported until now originated from the stomach. We report the first case of a duodenal PAMT arising from the first part of the duodenum in a 19-year-old woman presenting with upper abdominal pain and an abdominal lump.
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http://dx.doi.org/10.1136/bcr-2015-210004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521542PMC
July 2015

Neurotransmitters in alcoholism: A review of neurobiological and genetic studies.

Authors:
Niladri Banerjee

Indian J Hum Genet 2014 Jan;20(1):20-31

Amity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, India.

Recent advances in the study of alcoholism have thrown light on the involvement of various neurotransmitters in the phenomenon of alcohol addiction. Various neurotransmitters have been implicated in alcohol addiction due to their imbalance in the brain, which could be either due to their excess activity or inhibition. This review paper aims to consolidate and to summarize some of the recent papers which have been published in this regard. The review paper will give an overview of the neurobiology of alcohol addiction, followed by detailed reviews of some of the recent papers published in the context of the genetics of alcohol addiction. Furthermore, the author hopes that the present text will be found useful to novices and experts alike in the field of neurotransmitters in alcoholism.
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http://dx.doi.org/10.4103/0971-6866.132750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065474PMC
January 2014
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