Publications by authors named "Nikos K Karamanos"

100Publications

Special issue: Translating extracellular matrix: From cancer progression to therapeutics.

Semin Cancer Biol 2020 05 23;62:iii-v. Epub 2019 Oct 23.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry University of Patras, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2019.10.014DOI Listing
May 2020

Extracellular matrix: key structural and functional meshwork in health and disease.

FEBS J 2019 08;286(15):2826-2829

Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Greece.

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http://dx.doi.org/10.1111/febs.14992DOI Listing
August 2019

Hyaluronan-CD44 axis orchestrates cancer stem cell functions.

Cell Signal 2019 11 27;63:109377. Epub 2019 Jul 27.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26500 Patras, Greece.

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http://dx.doi.org/10.1016/j.cellsig.2019.109377DOI Listing
November 2019

Estrogen receptor-mediated targeting of the extracellular matrix network in cancer.

Semin Cancer Biol 2020 05 13;62:116-124. Epub 2019 Jul 13.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras, 26110, Greece; Foundation for Research and Technology-Hellas (FORTH)/Institute of Chemical Engineering Sciences (ICE-HT), Patras, 26110, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2019.07.006DOI Listing
May 2020

Dynamic Interplay between miRNAs and the Extracellular Matrix Influences the Tumor Microenvironment.

Trends Biochem Sci 2019 12 6;44(12):1076-1088. Epub 2019 Jul 6.

Biochemistry, Biochemical Analysis and Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras 26110, Greece; Foundation for Research and Technology-Hellas (FORTH)/ Institute of Chemical Engineering Sciences (ICE-HT), Patras 26110, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.tibs.2019.06.007DOI Listing
December 2019

Tumorigenic functions of serglycin: Regulatory roles in epithelial to mesenchymal transition and oncogenic signaling.

Semin Cancer Biol 2020 05 4;62:108-115. Epub 2019 Jul 4.

Biochemistry, Biochemical Analysis & Matrix Pathobiochemistry Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras 26110, Greece. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S1044579X193004
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http://dx.doi.org/10.1016/j.semcancer.2019.07.004DOI Listing
May 2020

The extracellular matrix as a multitasking player in disease.

FEBS J 2019 08 11;286(15):2830-2869. Epub 2019 Apr 11.

Biochemistry, Biochemical Analysis & Matrix Pathobiochemistry Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Greece.

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http://dx.doi.org/10.1111/febs.14818DOI Listing
August 2019

Hyaluronan: molecular size-dependent signaling and biological functions in inflammation and cancer.

FEBS J 2019 08 21;286(15):2883-2908. Epub 2019 Feb 21.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Greece.

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http://dx.doi.org/10.1111/febs.14777DOI Listing
August 2019

Proteoglycan Chemical Diversity Drives Multifunctional Cell Regulation and Therapeutics.

Chem Rev 2018 09 11;118(18):9152-9232. Epub 2018 Sep 11.

Department of Pathology, Anatomy and Cell Biology, Sidney Kimmel Medical College , Thomas Jefferson University , Philadelphia , Pennsylvania 10107 , United States.

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http://pubs.acs.org/doi/10.1021/acs.chemrev.8b00354
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http://dx.doi.org/10.1021/acs.chemrev.8b00354DOI Listing
September 2018

Matrix modeling and remodeling: A biological interplay regulating tissue homeostasis and diseases.

Matrix Biol 2019 01 18;75-76:1-11. Epub 2018 Aug 18.

Department of Pathology, Anatomy, and Cell Biology, Cancer Cell Biology and Signaling Program, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA 19107, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S0945053X183035
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http://dx.doi.org/10.1016/j.matbio.2018.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377817PMC
January 2019

Advances in targeting epidermal growth factor receptor signaling pathway in mammary cancer.

Cell Signal 2018 11 31;51:99-109. Epub 2018 Jul 31.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26110, Greece; Foundation for Research and Technology-Hellas (FORTH), Institute of Chemical Engineering Sciences (ICE-HT), 26504 Patras, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2018.07.010DOI Listing
November 2018

Serglycin promotes breast cancer cell aggressiveness: Induction of epithelial to mesenchymal transition, proteolytic activity and IL-8 signaling.

Matrix Biol 2018 12 26;74:35-51. Epub 2018 May 26.

Biochemistry, Biochemical Analysis and Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras 26110, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2018.05.011DOI Listing
December 2018

Tumor-suppressive functions of 4-MU on breast cancer cells of different ER status: Regulation of hyaluronan/HAS2/CD44 and specific matrix effectors.

Matrix Biol 2019 05 16;78-79:118-138. Epub 2018 Apr 16.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26110 Patras, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2018.04.007DOI Listing
May 2019

The apparent competitive action of ECM proteases and cross-linking enzymes during fibrosis: Applications to drug discovery.

Adv Drug Deliv Rev 2018 04 5;129:4-15. Epub 2018 Apr 5.

Department of Biological Regulation, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2018.03.004DOI Listing
April 2018

Proteoglycans remodeling in cancer: Underlying molecular mechanisms.

Matrix Biol 2019 01 8;75-76:220-259. Epub 2017 Nov 8.

Biochemistry, Biochemical Analysis & Matrix Pathobiochemistry Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26500 Patras, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2017.10.008DOI Listing
January 2019

Insights into the key roles of epigenetics in matrix macromolecules-associated wound healing.

Adv Drug Deliv Rev 2018 04 24;129:16-36. Epub 2017 Oct 24.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras 26110, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2017.10.008DOI Listing
April 2018

Extracellular matrix alterations in senescent cells and their significance in tissue homeostasis.

Matrix Biol 2019 01 21;75-76:27-42. Epub 2017 Oct 21.

Laboratory of Cell Proliferation and Ageing, Institute of Biosciences and Applications, National Centre for Scientific Research "Demokritos", Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2017.10.004DOI Listing
January 2019

Estrogen receptor beta as epigenetic mediator of miR-10b and miR-145 in mammary cancer.

Matrix Biol 2017 12 8;64:94-111. Epub 2017 Aug 8.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras 26110, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2017.08.002DOI Listing
December 2017

IGF-IR cooperates with ERα to inhibit breast cancer cell aggressiveness by regulating the expression and localisation of ECM molecules.

Sci Rep 2017 01 12;7:40138. Epub 2017 Jan 12.

Biochemistry, Biochemical Analysis &Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras 26110, Greece.

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http://dx.doi.org/10.1038/srep40138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228153PMC
January 2017

Matrix pathobiology-central roles for proteoglycans and heparanase in health and disease.

FEBS J 2017 01;284(1):7-9

Biochemistry Laboratory, Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Department of Chemistry, University of Patras, Greece.

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http://dx.doi.org/10.1111/febs.13945DOI Listing
January 2017

Syndecans - key regulators of cell signaling and biological functions.

FEBS J 2017 01 18;284(1):27-41. Epub 2016 Nov 18.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Greece.

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http://dx.doi.org/10.1111/febs.13940DOI Listing
January 2017

Roles and targeting of the HAS/hyaluronan/CD44 molecular system in cancer.

Matrix Biol 2017 05 13;59:3-22. Epub 2016 Oct 13.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26500 Patras, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2016.10.001DOI Listing
May 2017

Data on the putative role of p53 in breast cancer cell adhesion: Technical information for adhesion assay.

Data Brief 2016 Dec 30;9:568-572. Epub 2016 Sep 30.

Department of Anatomy-Histology-Embryology, School of Medicine, University of Crete, Heraklion, Greece.

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http://dx.doi.org/10.1016/j.dib.2016.09.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061116PMC
December 2016

IGF-I/EGF and E2 signaling crosstalk through IGF-IR conduit point affects breast cancer cell adhesion.

Matrix Biol 2016 12 25;56:95-113. Epub 2016 Jun 25.

Laboratory of Anatomy-Histology-Embryology, School of Medicine, University of Crete, Heraklion, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2016.06.005DOI Listing
December 2016

Estrogen receptor beta modulates breast cancer cells functional properties, signaling and expression of matrix molecules.

Matrix Biol 2016 12 11;56:4-23. Epub 2016 May 11.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras, Greece; Foundation for Research and Technology-Hellas (FORTH), Patras, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2016.05.003DOI Listing
December 2016

Increased Expression of Serglycin in Specific Carcinomas and Aggressive Cancer Cell Lines.

Biomed Res Int 2015 25;2015:690721. Epub 2015 Oct 25.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26500 Patras, Greece.

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http://dx.doi.org/10.1155/2015/690721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637082PMC
September 2016

Extracellular matrix structure.

Adv Drug Deliv Rev 2016 Feb 10;97:4-27. Epub 2015 Nov 10.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26500 Patras, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2015.11.001DOI Listing
February 2016

Syndecan-1 alters heparan sulfate composition and signaling pathways in malignant mesothelioma.

Cell Signal 2015 Oct 23;27(10):2054-67. Epub 2015 Jul 23.

Karolinska Institutet, Department of Laboratory Medicine, Division of Pathology, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.cellsig.2015.07.017DOI Listing
October 2015

Increased β-glucuronidase activity in bronchoalveolar lavage fluid of children with bacterial lung infection: A case-control study.

Respirology 2015 Nov 14;20(8):1248-54. Epub 2015 Jul 14.

Respiratory Unit, Department of Paediatrics, University General Hospital of Patras, Rion-Patras, Greece.

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http://dx.doi.org/10.1111/resp.12596DOI Listing
November 2015

Insights into the key roles of proteoglycans in breast cancer biology and translational medicine.

Biochim Biophys Acta 2015 Apr 28;1855(2):276-300. Epub 2015 Mar 28.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26500 Patras, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2015.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433619PMC
April 2015

Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells.

Matrix Biol 2015 Apr 27;43:42-60. Epub 2015 Feb 27.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras 26110, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2015.02.008DOI Listing
April 2015

Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer.

FEBS J 2014 Nov 6;281(22):5023-42. Epub 2014 Nov 6.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Greece.

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http://dx.doi.org/10.1111/febs.12927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036392PMC
November 2014

Novel insights into matrix pathobiology regulatory mechanisms in health and disease.

FEBS J 2014 Nov 6;281(22):4978-9. Epub 2014 Nov 6.

Department of Chemistry, Laboratory of Biochemistry, Biochemical Analysis and Matrix Pathobiology Research Group, University of Patras, Greece.

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http://dx.doi.org/10.1111/febs.13106DOI Listing
November 2014

Preparation and toxicological assessment of functionalized carbon nanotube-polymer hybrids.

PLoS One 2014 17;9(9):e107029. Epub 2014 Sep 17.

Department of Chemistry, University of Patras, Patras, Greece; Foundation for Research and Technology-Hellas (FORTH) / Institute of Chemical Engineering Sciences (ICE-HT), Rio-Patras, Greece.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107029PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167694PMC
January 2016

Advances and advantages of nanomedicine in the pharmacological targeting of hyaluronan-CD44 interactions and signaling in cancer.

Adv Cancer Res 2014 ;123:277-317

Biochemistry, Biochemical Analysis and Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras, Greece; Foundation for Research and Technology, Institute of Chemical Engineering Sciences (FORTH/ICE-HT), Patras, Greece. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-800092-2.00011-3DOI Listing
April 2015

Matrix-mediated cell behaviour and properties.

Biochim Biophys Acta 2014 Aug;1840(8):2385

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http://dx.doi.org/10.1016/j.bbagen.2014.05.015DOI Listing
August 2014

EGFR and HER2 exert distinct roles on colon cancer cell functional properties and expression of matrix macromolecules.

Biochim Biophys Acta 2014 Aug 2;1840(8):2651-61. Epub 2014 May 2.

Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2014.04.019DOI Listing
August 2014

The differential proliferative response of fetal and adult human skin fibroblasts to TGF-β is retained when cultured in the presence of fibronectin or collagen.

Biochim Biophys Acta 2014 Aug 13;1840(8):2635-42. Epub 2014 Apr 13.

Laboratory for Cell Proliferation & Ageing, Institute of Biosciences and Applications, National Centre for Scientific Research "Demokritos", 153 10 Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2014.04.004DOI Listing
August 2014

Syndecans as modulators and potential pharmacological targets in cancer progression.

Front Oncol 2014 3;4. Epub 2014 Feb 3.

Biochemistry, Biochemical Analysis and Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras , Patras , Greece.

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http://dx.doi.org/10.3389/fonc.2014.00004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910246PMC
June 2014

Serglycin: at the crossroad of inflammation and malignancy.

Front Oncol 2014 Jan 13;3:327. Epub 2014 Jan 13.

Laboratory of Biochemistry, Department of Chemistry, University of Patras , Patras , Greece.

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http://dx.doi.org/10.3389/fonc.2013.00327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888995PMC
January 2014

The roles of hyaluronan/RHAMM/CD44 and their respective interactions along the insidious pathways of fibrosarcoma progression.

Biomed Res Int 2013 5;2013:929531. Epub 2013 Sep 5.

Department of Histology-Embryology, School of Medicine, University of Crete, 71003 Heraklion, Greece.

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http://dx.doi.org/10.1155/2013/929531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780471PMC
April 2014

Cross-talk between estradiol receptor and EGFR/IGF-IR signaling pathways in estrogen-responsive breast cancers: focus on the role and impact of proteoglycans.

Matrix Biol 2014 Apr 21;35:182-93. Epub 2013 Sep 21.

Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras 26110, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2013.09.002DOI Listing
April 2014

Lumican affects tumor cell functions, tumor-ECM interactions, angiogenesis and inflammatory response.

Matrix Biol 2014 Apr 21;35:206-14. Epub 2013 Sep 21.

Department of Anatomy-Histology-Embryology, Medical School, University of Crete, Heraklion 71003, Greece.

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http://dx.doi.org/10.1016/j.matbio.2013.09.003DOI Listing
April 2014

PDGF/PDGFR signaling and targeting in cancer growth and progression: Focus on tumor microenvironment and cancer-associated fibroblasts.

Curr Pharm Des 2014 ;20(17):2843-8

Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26110 Patras, Greece.

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http://dx.doi.org/10.2174/13816128113199990592DOI Listing
September 2015

Expression of syndecan-4 and correlation with metastatic potential in testicular germ cell tumours.

Biomed Res Int 2013 15;2013:214864. Epub 2013 Jun 15.

Hematology Division, Department of Internal Medicine, University Hospital of Patras, 26500 Patras, Greece.

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http://dx.doi.org/10.1155/2013/214864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697279PMC
February 2014

Efficacy versus safety concerns for aerosol chemotherapy in non-small-cell lung cancer: a future dilemma for micro-oncology.

Future Oncol 2013 Apr;9(4):505-25

University Pulmonary Department-Interventional Unit, Ruhrland Clinic, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.2217/fon.12.205DOI Listing
April 2013

Special issue: Proteoglycans: signaling, targeting and therapeutics: introduction.

FEBS J 2013 May 18;280(10):2119. Epub 2013 Apr 18.

Biochemistry, Biochemical Analysis and Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Greece.

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http://dx.doi.org/10.1111/febs.12262DOI Listing
May 2013

New insights into the pathobiology of Down syndrome--hyaluronan synthase-2 overexpression is regulated by collagen VI α2 chain.

FEBS J 2013 May 28;280(10):2418-30. Epub 2013 Mar 28.

Laboratory of Biochemistry, Department of Surgical and Morphological Sciences, School of Medicine, University of Insubria, Varese, Italy.

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http://dx.doi.org/10.1111/febs.12220DOI Listing
May 2013

Cell-surface serglycin promotes adhesion of myeloma cells to collagen type I and affects the expression of matrix metalloproteinases.

FEBS J 2013 May 1;280(10):2342-52. Epub 2013 Mar 1.

Laboratory of Biochemistry, Department of Chemistry, University of Patras, Greece.

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http://dx.doi.org/10.1111/febs.12179DOI Listing
May 2013

Syndecan-2 is a key regulator of transforming growth factor beta 2/Smad2-mediated adhesion in fibrosarcoma cells.

IUBMB Life 2013 Feb 7;65(2):134-43. Epub 2013 Jan 7.

Department of Histology-Embryology, Medical School, University of Crete, Heraklion, Greece.

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http://dx.doi.org/10.1002/iub.1112DOI Listing
February 2013

Vectors for inhaled gene therapy in lung cancer. Application for nano oncology and safety of bio nanotechnology.

Int J Mol Sci 2012 29;13(9):10828-62. Epub 2012 Aug 29.

Pulmonary Department-Oncology Unit, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki 57010, Greece; E-Mails: (K.P.); (K.D.); (K.Z.) ; Pulmonary Department-Interventional Unit, "Ruhrland Klinik", University of Essen, Essen 45239, Germany.

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http://dx.doi.org/10.3390/ijms130910828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472716PMC
March 2016

The biology of small leucine-rich proteoglycans in bone pathophysiology.

J Biol Chem 2012 Oct 9;287(41):33926-33. Epub 2012 Aug 9.

Department of Histology-Embryology, Medical School, University of Crete, Greece.

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http://dx.doi.org/10.1074/jbc.R112.379602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464503PMC
October 2012

Glycosaminoglycans: from "cellular glue" to novel therapeutical agents.

Curr Opin Pharmacol 2012 Apr 9;12(2):220-2. Epub 2012 Feb 9.

University of Patras, Greece.

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http://dx.doi.org/10.1016/j.coph.2011.12.003DOI Listing
April 2012

Wild blueberry (V. angustifolium)-enriched diets alter aortic glycosaminoglycan profile in the spontaneously hypertensive rat.

J Nutr Biochem 2012 Aug 16;23(8):961-5. Epub 2011 Sep 16.

Food Science and Human Nutrition, University of Maine, Orono, ME 04469, USA.

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http://dx.doi.org/10.1016/j.jnutbio.2011.05.002DOI Listing
August 2012

Parathyroid hormone affects the fibroblast growth factor-proteoglycan signaling axis to regulate osteosarcoma cell migration.

FEBS J 2011 Oct 8;278(19):3782-92. Epub 2011 Sep 8.

Department of Histology-Embryology, Medical School, University of Crete, Heraklion, Greece.

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http://dx.doi.org/10.1111/j.1742-4658.2011.08300.xDOI Listing
October 2011

Lumican regulates osteosarcoma cell adhesion by modulating TGFβ2 activity.

Int J Biochem Cell Biol 2011 Jun 21;43(6):928-35. Epub 2011 Mar 21.

Department of Histology-Embryology, Medical School, University of Crete, Heraklion, Greece.

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http://dx.doi.org/10.1016/j.biocel.2011.03.008DOI Listing
June 2011

Hyaluronan-CD44 interactions as potential targets for cancer therapy.

FEBS J 2011 May 25;278(9):1429-43. Epub 2011 Mar 25.

Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1111/j.1742-4658.2011.08071.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166356PMC
May 2011

Heparin plays a key regulatory role via a p53/FAK-dependent signaling in melanoma cell adhesion and migration.

IUBMB Life 2011 Feb 24;63(2):109-19. Epub 2011 Feb 24.

Department of Histology, Medical School, University of Crete, Heraklion 71003, Greece.

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http://dx.doi.org/10.1002/iub.421DOI Listing
February 2011

Heparan sulfate: biological significance, tools for biochemical analysis and structural characterization.

Biomed Chromatogr 2011 Jan;25(1-2):11-20

Department of Chemistry, Laboratory of Biochemistry, University of Patras, Patras, Greece.

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http://dx.doi.org/10.1002/bmc.1536DOI Listing
January 2011

Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting.

FEBS J 2011 Jan 19;278(1):16-27. Epub 2010 Nov 19.

Department of Chemistry, Laboratory of Biochemistry, University of Patras, Greece.

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http://dx.doi.org/10.1111/j.1742-4658.2010.07919.xDOI Listing
January 2011

Glycosaminoglycans as key molecules in atherosclerosis: the role of versican and hyaluronan.

Curr Med Chem 2010 ;17(33):4018-26

Department of Cardiovascular and Thoracic Surgery, University of Thessaly, Larissa, Greece.

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http://dx.doi.org/10.2174/092986710793205354DOI Listing
May 2011

Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting.

FEBS J 2010 Oct 31;277(19):3904-23. Epub 2010 Aug 31.

Department of Chemistry, University of Patras, Patras, Greece.

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http://dx.doi.org/10.1111/j.1742-4658.2010.07800.xDOI Listing
October 2010

Crocetin inhibits invasiveness of MDA-MB-231 breast cancer cells via downregulation of matrix metalloproteinases.

Planta Med 2011 Jan 27;77(2):146-51. Epub 2010 Aug 27.

Department of Pharmacy, Laboratory of Pharmacognosy & Chemistry of Natural Products, University of Patras, Rion, Greece.

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http://dx.doi.org/10.1055/s-0030-1250178DOI Listing
January 2011

A modified protocol for isolation and purity evaluation of a staphylococcal acidic polysaccharide by chromatography and capillary electrophoresis.

Biomed Chromatogr 2011 May 23;25(5):531-4. Epub 2010 Aug 23.

Laboratory of Microbiology, School of Medicine, University of Patras, Patras, Greece.

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http://dx.doi.org/10.1002/bmc.1490DOI Listing
May 2011

Parathyroid hormone (PTH) peptides through the regulation of hyaluronan metabolism affect osteosarcoma cell migration.

IUBMB Life 2010 May;62(5):377-86

Department of Histology, Division of Morphology, School of Medicine, University of Crete, Heraklion, Greece.

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http://dx.doi.org/10.1002/iub.320DOI Listing
May 2010

Tear analysis of ascorbic acid, uric acid and malondialdehyde with capillary electrophoresis.

Biomed Chromatogr 2010 Aug;24(8):852-7

Department of Ophthalmology, School of Medicine, University of Patras, 26504 Patras, Greece.

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http://dx.doi.org/10.1002/bmc.1376DOI Listing
August 2010

bFGF induces changes in hyaluronan synthase and hyaluronidase isoform expression and modulates the migration capacity of fibrosarcoma cells.

Biochim Biophys Acta 2009 Oct 3;1790(10):1258-65. Epub 2009 Jul 3.

Department of Histology, Division of Morphology, School of Medicine, University of Crete, 71110, Heraklion, Greece.

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http://dx.doi.org/10.1016/j.bbagen.2009.06.013DOI Listing
October 2009

The impact of zoledronic acid therapy in survival of lung cancer patients with bone metastasis.

Int J Cancer 2009 Oct;125(7):1705-9

Lung Tumor Research Section, Pulmonary Department, Aristotle University of Thessaloniki, G. Papanikolaou Hospital, Thessaloniki, Greece.

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http://dx.doi.org/10.1002/ijc.24470DOI Listing
October 2009

Estradiol-estrogen receptor: a key interplay of the expression of syndecan-2 and metalloproteinase-9 in breast cancer cells.

Mol Oncol 2008 Oct 18;2(3):223-32. Epub 2008 Jun 18.

Laboratory of Biochemistry, Section of Organic Chemistry, Biochemistry and Natural Products, Department of Chemistry, University of Patras, 261 10 Patras, Greece.

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http://dx.doi.org/10.1016/j.molonc.2008.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527808PMC
October 2008

Fibroblast growth factor-2 modulates melanoma adhesion and migration through a syndecan-4-dependent mechanism.

Int J Biochem Cell Biol 2009 Jun 6;41(6):1323-31. Epub 2008 Dec 6.

Department of Histology, Medical School, University of Crete, Heraklion, 71003, Greece.

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http://dx.doi.org/10.1016/j.biocel.2008.11.008DOI Listing
June 2009

Lumican, a small leucine-rich proteoglycan.

IUBMB Life 2008 Dec;60(12):818-23

Lab of Histology, Medical School, University of Crete, Heraklion, Greece.

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http://dx.doi.org/10.1002/iub.131DOI Listing
December 2008

Small tyrosine kinase inhibitors as key molecules in the expression of metalloproteinases by solid tumors.

Connect Tissue Res 2008 ;49(3):211-4

Department of Chemistry, Laboratory of Biochemistry, University of Patras, Patras, Greece.

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http://dx.doi.org/10.1080/03008200802143307DOI Listing
September 2008

Hyaluronan and chondroitin sulfate proteoglycans in the supramolecular organization of the mammalian vitreous body.

Connect Tissue Res 2008 ;49(3):124-8

Laboratory of Biological Chemistry, School of Medicine, University of Patras, Patras, Greece.

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http://dx.doi.org/10.1080/03008200802148496DOI Listing
September 2008

The biological role of chondroitin sulfate in cancer and chondroitin-based anticancer agents.

In Vivo 2008 May-Jun;22(3):385-9

Department of Chemistry, Laboratory of Biochemistry, University of Patras, Greece.

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August 2008

Glycosaminoglycan in cerebrum, cerebellum and brainstem of young sheep brain with particular reference to compositional and structural variations of chondroitin-dermatan sulfate and hyaluronan.

Biomed Chromatogr 2008 Sep;22(9):931-8

Laboratory of Biochemistry, Section of Organic Chemistry, Biochemistry and Natural Products, Department of Chemistry, University of Patras, 26500 Patras, Greece.

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http://dx.doi.org/10.1002/bmc.1010DOI Listing
September 2008

Decorin-induced growth inhibition is overcome through protracted expression and activation of epidermal growth factor receptors in osteosarcoma cells.

Mol Cancer Res 2008 May;6(5):785-94

Department of Histology, Division of Morphology, School of Medicine, University of Crete, 71110 Heraklion, Greece.

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http://dx.doi.org/10.1158/1541-7786.MCR-07-0165DOI Listing
May 2008

Imatinib mesylate inhibits proliferation and exerts an antifibrotic effect in human breast stroma fibroblasts.

Mol Cancer Res 2008 May;6(5):706-14

Laboratory of Cell Proliferation and Ageing, Institute of Biology, National Center for Scientific Research "Demokritos," 153 10 Athens, Greece.

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http://dx.doi.org/10.1158/1541-7786.MCR-07-0355DOI Listing
May 2008

Heparin--a unique stimulator of human colon cancer cells' growth.

IUBMB Life 2008 May;60(5):333-40

Department of Histology, Division of Morphology, School of Medicine, University of Crete, Heraklion, Greece.

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http://dx.doi.org/10.1002/iub.70DOI Listing
May 2008