Nikolaus Gassler

Nikolaus Gassler

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Nikolaus Gassler

Nikolaus Gassler

Publications by authors named "Nikolaus Gassler"

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CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4 T-Cell-Dependent Control of Senescence.

Gastroenterology 2019 05 30;156(6):1877-1889.e4. Epub 2019 Jan 30.

Department of Medicine III, RWTH-University Hospital Aachen, Aachen, Germany; Department of Hepatology/Gastroenterology, Charité University Medical Center, Berlin, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085193034
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http://dx.doi.org/10.1053/j.gastro.2019.01.247DOI Listing
May 2019

Targeting Wnt Signaling via Notch in Intestinal Carcinogenesis.

Cancers (Basel) 2019 Apr 18;11(4). Epub 2019 Apr 18.

Institute of Pathology, RWTH Aachen University, 52074 Aachen, Germany.

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https://www.mdpi.com/2072-6694/11/4/555
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http://dx.doi.org/10.3390/cancers11040555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520938PMC
April 2019

Paneth cells in intestinal physiology and pathophysiology.

Authors:
Nikolaus Gassler

World J Gastrointest Pathophysiol 2017 Nov;8(4):150-160

Institute of Pathology, RWTH Aachen University, Braunschweig 38114, Germany.

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http://dx.doi.org/10.4291/wjgp.v8.i4.150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696613PMC
November 2017

Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis.

Biochim Biophys Acta Mol Basis Dis 2017 09 7;1863(9):2093-2110. Epub 2017 Apr 7.

Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry, RWTH University Hospital Aachen, Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2017.04.006DOI Listing
September 2017

PilY1 Promotes Infection of Human Lung Tissue Explants and Contributes to Bacterial Adhesion, Host Cell Invasion, and Twitching Motility.

Front Cell Infect Microbiol 2017 7;7:63. Epub 2017 Mar 7.

Institut für Mikrobiologie, Technische Universität BraunschweigBraunschweig, Germany; Helmholtz Center for Infection ResearchBraunschweig, Germany.

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http://dx.doi.org/10.3389/fcimb.2017.00063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339237PMC
June 2017

Low acyl-CoA synthetase 5 expression in colorectal carcinomas is prognostic for early tumour recurrence.

Pathol Res Pract 2017 Mar 26;213(3):261-266. Epub 2016 Sep 26.

Institute of Pathology, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany; Department of Pediatrics, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany.

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http://dx.doi.org/10.1016/j.prp.2016.09.002DOI Listing
March 2017

Wnt Lipidation and Modifiers in Intestinal Carcinogenesis and Cancer.

Cancers (Basel) 2016 Jul 18;8(7). Epub 2016 Jul 18.

Institute of Pathology, RWTH Aachen University, Aachen 52074, Germany.

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http://dx.doi.org/10.3390/cancers8070069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963811PMC
July 2016

Intestinal genetic inactivation of caspase-8 diminishes migration of enterocytes.

World J Gastroenterol 2015 Apr;21(15):4499-508

Elke Kaemmerer, Paula Kuhn, Ursula Schneider, Min Kyung Jeon, Christina Klaus, Miriam Schiffer, Danika Weisner, Jörg Jäkel, Nikolaus Gassler, Institute of Pathology, RWTH Aachen University, 52074 Aachen, Germany.

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http://dx.doi.org/10.3748/wjg.v21.i15.4499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402296PMC
April 2015

Beta-7 integrin controls enterocyte migration in the small intestine.

World J Gastroenterol 2015 Feb;21(6):1759-64

Elke Kaemmerer, Paula Kuhn, Ursula Schneider, Min Kyung Jeon, Christina Klaus, Julia Andruszkow, Michael Härer, Nikolaus Gassler, Institute of Pathology, RWTH Aachen University, 52074 Aachen, Germany.

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http://dx.doi.org/10.3748/wjg.v21.i6.1759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323451PMC
February 2015

An immunohistochemical assay on human tissue using a human primary antibody.

J Immunoassay Immunochem 2014 ;35(3):322-34

a Fraunhofer Institute for Molecular Biology and Applied Ecology IME , Aachen , Germany.

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http://dx.doi.org/10.1080/15321819.2013.864974DOI Listing
November 2014

Lipocalin-2 (LCN2) regulates PLIN5 expression and intracellular lipid droplet formation in the liver.

Biochim Biophys Acta 2014 Oct 31;1842(10):1513-24. Epub 2014 Jul 31.

Institute of Clinical Chemistry and Pathobiochemistry, RWTH University Hospital Aachen, Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2014.07.017DOI Listing
October 2014

Modulating effects of acyl-CoA synthetase 5-derived mitochondrial Wnt2B palmitoylation on intestinal Wnt activity.

World J Gastroenterol 2014 Oct;20(40):14855-64

Christina Klaus, Ursula Schneider, Nikolaus Gassler, Elke Kaemmerer, Institute of Pathology, RWTH Aachen University, 52074 Aachen, Germany.

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http://dx.doi.org/10.3748/wjg.v20.i40.14855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209548PMC
October 2014

New facets of keratin K77: interspecies variations of expression and different intracellular location in embryonic and adult skin of humans and mice.

Cell Tissue Res 2013 Dec 22;354(3):793-812. Epub 2013 Sep 22.

Genetics of Skin Carcinogenesis, A110, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany,

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http://dx.doi.org/10.1007/s00441-013-1716-5DOI Listing
December 2013

Molecular classification of colorectal carcinomas: the genotype-to-phenotype relation.

World J Gastroenterol 2013 Dec;19(45):8163-7

Elke Kaemmerer, Christina Klaus, Min Kyung Jeon, Nikolaus Gassler, Institute of Pathology, RWTH Aachen University, 52074 Aachen, Germany.

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http://dx.doi.org/10.3748/wjg.v19.i45.8163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857437PMC
December 2013

Intestinal barrier: Molecular pathways and modifiers.

World J Gastrointest Pathophysiol 2013 Nov;4(4):94-9

Min Kyung Jeon, Christina Klaus, Elke Kaemmerer, Nikolaus Gassler, Institute of Pathology, RWTH Aachen University, 52074 Aachen, Germany.

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http://dx.doi.org/10.4291/wjgp.v4.i4.94DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829455PMC
November 2013

Intestinal acyl-CoA synthetase 5: activation of long chain fatty acids and behind.

World J Gastroenterol 2013 Nov;19(42):7369-73

Christina Klaus, Min Kyung Jeon, Elke Kaemmerer, Nikolaus Gassler, Institute of Pathology, RWTH Aachen University, 52074 Aachen, Germany.

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http://dx.doi.org/10.3748/wjg.v19.i42.7369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831218PMC
November 2013

Coincidence of active Crohn's disease and florid endometriosis in the terminal ileum: a case report.

World J Gastroenterol 2013 Jul;19(27):4413-7

Department of Pediatrics and Institute of Pathology, RWTH Aachen University, D-52074 Aachen, Germany.

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http://dx.doi.org/10.3748/wjg.v19.i27.4413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718912PMC
July 2013

Factor VII activating protease (FSAP) exerts anti-inflammatory and anti-fibrotic effects in liver fibrosis in mice and men.

J Hepatol 2013 Jan 16;58(1):104-11. Epub 2012 Sep 16.

Institute of Clinical Chemistry and Pathobiochemistry, RWTH University Hospital, Aachen, Germany.

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http://dx.doi.org/10.1016/j.jhep.2012.09.007DOI Listing
January 2013

Sphingolipids in intestine and liver: How to analyze?

Authors:
Nikolaus Gassler

World J Gastrointest Pathophysiol 2012 Dec;3(6):99-101

Nikolaus Gassler, Institute of Pathology, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany.

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http://dx.doi.org/10.4291/wjgp.v3.i6.99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602439PMC
December 2012

Peptide-functionalized gold nanorods increase liver injury in hepatitis.

ACS Nano 2012 Oct 1;6(10):8767-77. Epub 2012 Oct 1.

Department of Medicine III, Medical Faculty, RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.

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http://dx.doi.org/10.1021/nn302502uDOI Listing
October 2012

Isolated arrhythmogenic left ventricular cardiomyopathy identified by cardiac magnetic resonance imaging.

Eur Heart J 2011 Nov 15;32(22):2840. Epub 2011 Jul 15.

Department of Cardiology, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.

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http://dx.doi.org/10.1093/eurheartj/ehr240DOI Listing
November 2011

Fatty acid binding receptors in intestinal physiology and pathophysiology.

World J Gastrointest Pathophysiol 2010 Dec;1(5):147-53

Elke Kaemmerer, Angela Schippers, Norbert Wagner, Department of Pediatrics, RWTH Aachen University, Aachen 52074, Germany.

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http://dx.doi.org/10.4291/wjgp.v1.i5.147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097959PMC
December 2010

Lipid-induced up-regulation of human acyl-CoA synthetase 5 promotes hepatocellular apoptosis.

Biochim Biophys Acta 2010 Sep 12;1801(9):1025-35. Epub 2010 May 12.

Institute of Pathology, RWTH Aachen University, Aachen, Germany.

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http://dx.doi.org/10.1016/j.bbalip.2010.04.010DOI Listing
September 2010

Application of magnetic resonance imaging in transgenic and chemical mouse models of hepatocellular carcinoma.

Mol Cancer 2010 Apr 29;9:94. Epub 2010 Apr 29.

UCSF Helen Diller Family Comprehensive Cancer Center 1450, 3rd Street, San Francisco, CA 94158-9001, USA.

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http://dx.doi.org/10.1186/1476-4598-9-94DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868806PMC
April 2010

Localization of the lipopolysaccharide recognition complex in the human healthy and inflamed premature and adult gut.

Inflamm Bowel Dis 2010 Jan;16(1):68-75

Department of Surgery, Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Maastricht University Medical Centre, Maastricht, the Netherlands.

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http://dx.doi.org/10.1002/ibd.20995DOI Listing
January 2010

Successful treatment of hepatic encephalopathy in a patient with acute lymphoblastic leukemia.

Acta Haematol 2009 29;122(4):216-20. Epub 2009 Oct 29.

Medizinische Klinik IV, Universitatsklinikum Aachen, RWTH Aachen University, Aachen, Germany.

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http://dx.doi.org/10.1159/000253029DOI Listing
December 2009

Expression of hemoglobin in rodent neurons.

J Cereb Blood Flow Metab 2009 Mar 31;29(3):585-95. Epub 2008 Dec 31.

Division of Systems Physiology, Department of Physiology and Pathophysiology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1038/jcbfm.2008.152DOI Listing
March 2009

Mucoepidermoid carcinoma of palatinal glands with exuberant foreign-body giant cell reaction.

Pathol Res Pract 2008 5;204(9):689-91. Epub 2008 Jun 5.

Institute of Pathology, RWTH Aachen University, Aachen, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S034403380800094
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http://dx.doi.org/10.1016/j.prp.2008.04.003DOI Listing
October 2008

Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury.

Lab Invest 2008 Oct 28;88(10):1090-100. Epub 2008 Jul 28.

Institute of Clinical Chemistry and Pathobiochemistry, RWTH-University Hospital Aachen, Aachen, Germany.

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http://dx.doi.org/10.1038/labinvest.2008.71DOI Listing
October 2008

Expression of the HPV11 E2 gene in transgenic mice does not result in alterations of the phenotypic pattern.

Transgenic Res 2008 Feb 16;17(1):1-8. Epub 2007 Aug 16.

German Cancer Research Centre, Heidelberg, F050, Im Neuenheimer Feld 280, Heidelberg, 69120, Germany.

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http://link.springer.com/content/pdf/10.1007/s11248-007-9130
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http://link.springer.com/10.1007/s11248-007-9130-y
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http://dx.doi.org/10.1007/s11248-007-9130-yDOI Listing
February 2008

Idiopathic megacolon.

Eur J Gastroenterol Hepatol 2007 May;19(5):399-400

University Heidelberg, Institute of Pathology, Heidelberg, Germany.

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http://dx.doi.org/10.1097/MEG.0b013e3280116cb8DOI Listing
May 2007

Regulation of differential pro- and anti-apoptotic signaling by glucocorticoids.

Apoptosis 2007 Feb;12(2):271-91

Department of Surgery, University of Heidelberg, Heidelberg, Germany.

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http://link.springer.com/10.1007/s10495-006-0624-5
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http://dx.doi.org/10.1007/s10495-006-0624-5DOI Listing
February 2007

A new tool for experimental tumour research.

Oncol Rep 2006 May;15(5):1153-5

Molecular Urooncology, German Cancer Research Center, Heidelberg, Germany.

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May 2006

Distinct immunohistochemical expression of osteopontin in the adult rat major salivary glands.

J Mol Histol 2006 Jan 3;37(1-2):53-60. Epub 2006 Jul 3.

Division of Nephrology, Medical Clinic III, University of Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/M, Germany.

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http://link.springer.com/10.1007/s10735-006-9031-z
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http://dx.doi.org/10.1007/s10735-006-9031-zDOI Listing
January 2006

Impaired expression of acyl-CoA synthetase 5 in sporadic colorectal adenocarcinomas.

J Pathol 2005 Nov;207(3):295-300

Institute of Pathology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/path.1831DOI Listing
November 2005

Characterization of a novel human type II epithelial keratin K1b, specifically expressed in eccrine sweat glands.

J Invest Dermatol 2005 Sep;125(3):428-44

Division of Cell Biology, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1111/j.0022-202X.2005.23860.xDOI Listing
September 2005

Synthesis of junctional proteins in metastasizing colon cancer cells.

Eur J Cell Biol 2005 Mar;84(2-3):417-30

Division of Cell Biology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ejcb.2005.01.005DOI Listing
March 2005

Wnt-signaling and apoptosis after neoadjuvant short-term radiotherapy for rectal cancer.

Int J Oncol 2004 Dec;25(6):1543-9

Department of Pathology, University of Heidelberg, Heidelberg, Germany.

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December 2004