Nikolas von Bubnoff

Nikolas von Bubnoff

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Nikolas von Bubnoff

Nikolas von Bubnoff

Publications by authors named "Nikolas von Bubnoff"

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Extracellular Vesicles: Subcellular Organelles With the Potential to Spread Cancer Resistance.

Anticancer Res 2019 Jul;39(7):3395-3404

Clinic for Hematology and Oncology, Experimental Oncology, University Medical Center Schleswig-Holstein (UKSH), University of Luebeck, Luebeck, Germany.

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http://dx.doi.org/10.21873/anticanres.13483DOI Listing
July 2019

Platelets and Immune Responses During Thromboinflammation.

Front Immunol 2019 26;10:1731. Epub 2019 Jul 26.

University Hospital, Medical Clinic II, University Heart Center Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.01731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676797PMC
July 2019

Ponatinib: A Third-Generation Inhibitor for the Treatment of CML.

Recent Results Cancer Res 2018;212:109-118

Department of Medicine I, Medical Center, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1007/978-3-319-91439-8_5DOI Listing
May 2019

Ruxolitinib.

Recent Results Cancer Res 2018;212:119-132

Department of Hematology and Oncology, University of Freiburg Medical Center, Hugstetter Str. 55, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1007/978-3-319-91439-8_6DOI Listing
May 2019

Water pipe smoking as a cause of secondary erythrocytosis.

Oxf Med Case Reports 2019 May 31;2019(5):omz027. Epub 2019 May 31.

Department of Medicine I, Medical Center-University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1093/omcr/omz027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544420PMC
May 2019

Liquid Biopsy: Approaches to Dynamic Genotyping in Cancer.

Oncol Res Treat 2017 13;40(7-8):409-416. Epub 2017 Jul 13.

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http://dx.doi.org/10.1159/000478864DOI Listing
September 2018

Extracellular vesicles or free circulating DNA: where to search for BRAF and cKIT mutations?

Nanomedicine 2018 04 27;14(3):875-882. Epub 2017 Dec 27.

Institute for Infection Prevention and Hospital Epidemiology; Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2017.12.009DOI Listing
April 2018

Ruxolitinib for the treatment of patients with steroid-refractory GVHD: an introduction to the REACH  trials.

Immunotherapy 2018 04 10;10(5):391-402. Epub 2018 Jan 10.

Department of Hematology, Oncology & Stem Cell Transplantation, University Hospital Freiburg, Hugstetter Str. 55, 79106 Freiburg im Breisgau, Germany.

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https://www.futuremedicine.com/doi/10.2217/imt-2017-0156
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http://dx.doi.org/10.2217/imt-2017-0156DOI Listing
April 2018

Liquid biopsy to monitor melanoma patients.

J Dtsch Dermatol Ges 2018 Apr 7;16(4):405-414. Epub 2018 Mar 7.

Skin Cancer Unit, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1111/ddg.13461DOI Listing
April 2018

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 Apr;24(4):526

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http://dx.doi.org/10.1038/nm0418-526cDOI Listing
April 2018

Liquid Biopsy zur Überwachung von Melanompatienten.

J Dtsch Dermatol Ges 2018 Apr;16(4):405-416

Klinische Kooperationseinheit Klinische Kooperationseinheit Dermatoonkologie des Deutschen, Krebsforschungszentrums (DKFZ), Heidelberg, Deutschland.

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http://dx.doi.org/10.1111/ddg.13461_gDOI Listing
April 2018

Indoleamine 2,3-Dioxygenase Expression in Primary Cutaneous Melanoma Correlates with Breslow Thickness and Is of Significant Prognostic Value for Progression-Free Survival.

J Invest Dermatol 2018 03 18;138(3):679-687. Epub 2017 Oct 18.

Department of Dermatology and Venereology, Medical Center-University of Freiburg, Faculty of Medicine, Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.09.036DOI Listing
March 2018

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 03 12;24(3):282-291. Epub 2018 Feb 12.

Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/nm.4484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029618PMC
March 2018

Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients.

PLoS One 2016 16;11(8):e0161012. Epub 2016 Aug 16.

Cancer Genome Research Group, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Im Neuenheimer Feld 460, Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161012PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987014PMC
July 2017

A specific spectral signature of serum and plasma-derived extracellular vesicles for cancer screening.

Nanomedicine 2017 04 10;13(3):835-841. Epub 2016 Dec 10.

Institute for Environmental Health Sciences and Hospital Infection Control, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2016.11.016DOI Listing
April 2017

Sensitive and accurate quantification of JAK2 V617F mutation in chronic myeloproliferative neoplasms by droplet digital PCR.

Ann Hematol 2016 Apr 1;95(5):739-44. Epub 2016 Mar 1.

Department of Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1007/s00277-016-2623-0DOI Listing
April 2016

Ponatinib: a third-generation inhibitor for the treatment of CML.

Recent Results Cancer Res 2014 ;201:99-107

University of Freiburg - Medical Center - Department of Medicine I, Freiburg, Germany.

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http://dx.doi.org/10.1007/978-3-642-54490-3_5DOI Listing
September 2014

Ruxolitinib.

Recent Results Cancer Res 2014 ;201:249-57

University Freiburg-Medical Center, Hugstetterstrasse 55, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1007/978-3-642-54490-3_16DOI Listing
September 2014

Detection of mutant free circulating tumor DNA in the plasma of patients with gastrointestinal stromal tumor harboring activating mutations of CKIT or PDGFRA.

Clin Cancer Res 2013 Sep 5;19(17):4854-67. Epub 2013 Jul 5.

Center for Internal Medicine, Department of Hematology/Oncology and Hemostaseology, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0765DOI Listing
September 2013

Sequential inhibitor therapy in CML: in vitro simulation elucidates the pattern of resistance mutations after second- and third-line treatment.

Clin Cancer Res 2013 Jun 2;19(11):2962-72. Epub 2013 Apr 2.

III. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, München, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0052DOI Listing
June 2013

Asymmetric kinase dimer formation is crucial for the activation of oncogenic EGFRvIII but not for ERBB3 phosphorylation.

Cell Commun Signal 2013 Jun 10;11:39. Epub 2013 Jun 10.

Department Medicine I, University Medical Center Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1186/1478-811X-11-39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726407PMC
June 2013

Oncologist's/haematologist's view on the roles of pathologists for molecular targeted cancer therapy.

J Cell Mol Med 2010 Apr 16;14(4):805-17. Epub 2010 Feb 16.

III. Medical Department, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1111/j.1582-4934.2010.01032.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823113PMC
April 2010

Chronic myelogenous leukemia: treatment and monitoring.

Dtsch Arztebl Int 2010 Feb 19;107(7):114-21. Epub 2010 Feb 19.

Medizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Germany.

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https://www.aerzteblatt.de/10.3238/arztebl.2010.0114
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http://dx.doi.org/10.3238/arztebl.2010.0114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835925PMC
February 2010

FMS-like tyrosine kinase 3-internal tandem duplication tyrosine kinase inhibitors display a nonoverlapping profile of resistance mutations in vitro.

Cancer Res 2009 Apr 24;69(7):3032-41. Epub 2009 Mar 24.

III. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, München, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2923DOI Listing
April 2009

Functional analysis of epidermal growth factor receptor (EGFR) mutations and potential implications for EGFR targeted therapy.

Clin Cancer Res 2009 Jan;15(2):460-7

Department of Internal Medicine III, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-1757DOI Listing
January 2009

Imatinib and leptomycin B are effective in overcoming imatinib-resistance due to Bcr-Abl amplification and clonal evolution but not due to Bcr-Abl kinase domain mutation.

Haematologica 2008 Nov 25;93(11):1718-22. Epub 2008 Aug 25.

Dept. of Internal Medicine III, Technical University of Munich, Ismaningerstr. 22, 81675 Munich, Germany.

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http://dx.doi.org/10.3324/haematol.13207DOI Listing
November 2008

Bcr-Abl resistance screening predicts a limited spectrum of point mutations to be associated with clinical resistance to the Abl kinase inhibitor nilotinib (AMN107).

Blood 2006 Aug 13;108(4):1328-33. Epub 2006 Apr 13.

Department of Internal Medicine III, Technical University of Munich, D-81675 Munich, Germany.

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http://dx.doi.org/10.1182/blood-2005-12-010132DOI Listing
August 2006

A cell-based screening strategy that predicts mutations in oncogenic tyrosine kinases: implications for clinical resistance in targeted cancer treatment.

Cell Cycle 2005 Mar 25;4(3):400-6. Epub 2005 Mar 25.

Department of Internal Medicine III, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.4161/cc.4.3.1560DOI Listing
March 2005

Inhibition of wild-type and mutant Bcr-Abl by pyrido-pyrimidine-type small molecule kinase inhibitors.

Cancer Res 2003 Oct;63(19):6395-404

Department of Internal Medicine III, Technical University of Munich, Trogerstrasse 32, D-81675 Munich, Germany.

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October 2003

BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: a prospective study.

Lancet 2002 Feb;359(9305):487-91

Department of Internal Medicine III, Laboratory of Leukemogenesis, Technical University of Munich, Ismaningerstrasse 22, 81675, Munich, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736020767
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http://dx.doi.org/10.1016/S0140-6736(02)07679-1DOI Listing
February 2002