Publications by authors named "Nikolai N Khodarev"

47Publications

Systemic miRNA delivery by nontoxic nanoscale coordination polymers limits epithelial-to-mesenchymal transition and suppresses liver metastases of colorectal cancer.

Biomaterials 2019 07 28;210:94-104. Epub 2019 Apr 28.

Department of Chemistry, The University of Chicago, Chicago, IL, 60637, USA; Department of Radiation and Cellular Oncology and the Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL, 60637, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2019.04.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579118PMC
July 2019

Intracellular RNA Sensing in Mammalian Cells: Role in Stress Response and Cancer Therapies.

Int Rev Cell Mol Biol 2019 19;344:31-89. Epub 2018 Oct 19.

Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.ircmb.2018.08.005DOI Listing
January 2020

DNA Methylation Controls Metastasis-Suppressive 14q32-Encoded miRNAs.

Cancer Res 2019 02 11;79(3):650-662. Epub 2018 Dec 11.

Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, Illinois.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-18-0692DOI Listing
February 2019

JAK2 Inhibitor SAR302503 Abrogates PD-L1 Expression and Targets Therapy-Resistant Non-small Cell Lung Cancers.

Mol Cancer Ther 2018 04 21;17(4):732-739. Epub 2018 Feb 21.

Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, The University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-0667DOI Listing
April 2018

Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors.

J Clin Oncol 2018 06 13;36(16):1611-1618. Epub 2018 Feb 13.

Jason J. Luke, Jeffrey M. Lemons, Theodore G. Karrison, Sean P. Pitroda, James M. Melotek, Yuanyuan Zha, Hania A. Al-Hallaq, Ainhoa Arina, Nikolai N. Khodarev, Linda Janisch, Paul Chang, Jyoti D. Patel, Gini F. Fleming, John Moroney, Manish R. Sharma, Mark J. Ratain, Thomas F. Gajewski, Ralph R. Weichselbaum, and Steven J. Chmura, The University of Chicago, Chicago, IL; Julia R. White, The Ohio State University, Columbus, OH.

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http://dx.doi.org/10.1200/JCO.2017.76.2229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978468PMC
June 2018

In Vivo Delivery and Therapeutic Effects of a MicroRNA on Colorectal Liver Metastases.

Mol Ther 2017 07 28;25(7):1588-1595. Epub 2017 Apr 28.

Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL 60637, USA; Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL 60637, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2017.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498809PMC
July 2017

CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response.

Cell Rep 2017 03;18(10):2373-2386

Division of Hematology/Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA; Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.02.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474321PMC
March 2017

Imaging of tumor clones with differential liver colonization.

Sci Rep 2015 Jun 22;5:10946. Epub 2015 Jun 22.

Department of Radiation and Cellular Oncology, Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL 60637.

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http://dx.doi.org/10.1038/srep10946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476146PMC
June 2015

microRNAs and oligometastasis.

Aging (Albany NY) 2015 Mar;7(3):146-7

The University of Chicago, Chicago, IL 60637, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394724PMC
http://dx.doi.org/10.18632/aging.100731DOI Listing
March 2015

Pseudomonas aeruginosa wound infection involves activation of its iron acquisition system in response to fascial contact.

J Trauma Acute Care Surg 2015 Apr;78(4):823-9

From the Departments of Surgery (M.K., S.C., I.F., O.Z., J.C.A.), Radiology and Cellular Oncology (N.N.K.), and Medicine (Y.H., E.C.), University of Chicago, Chicago, Illinois. O.Z. and J.C.A. are senior coauthors.

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http://dx.doi.org/10.1097/TA.0000000000000574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376013PMC
April 2015

Towards a molecular basis of oligometastatic disease: potential role of micro-RNAs.

Clin Exp Metastasis 2014 Aug 27;31(6):735-48. Epub 2014 Jun 27.

Department of Surgery, The University of Chicago, MC 5029, 5841 S. Maryland Ave, Chicago, IL, 60637, USA,

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http://dx.doi.org/10.1007/s10585-014-9664-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138440PMC
August 2014

RIG-I-like receptor LGP2 protects tumor cells from ionizing radiation.

Proc Natl Acad Sci U S A 2014 Jan 13;111(4):E484-91. Epub 2014 Jan 13.

Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, Center for Research Informatics, and The Marjorie B. Kovler Viral Oncology Laboratories, University of Chicago, Chicago, IL 60637.

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http://dx.doi.org/10.1073/pnas.1323253111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910628PMC
January 2014

Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth.

Clin Cancer Res 2012 Jun 21;18(11):3015-21. Epub 2012 May 21.

Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL 60637, USA.

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http://clincancerres.aacrjournals.org/content/early/2012/05/
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-11-3225DOI Listing
June 2012

The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity.

Cancer Res 2011 Apr 7;71(7):2488-96. Epub 2011 Feb 7.

Departments of Pathology and Radiation and Cellular Oncology, The Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-10-2820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070872PMC
April 2011

MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients.

BMC Med Genomics 2010 May 6;3:16. Epub 2010 May 6.

The Scripps Research Institute and Scripps Translational Science Institute, 3344 N Torrey Pines Court Ste, 300, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1186/1755-8794-3-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876055PMC
May 2010

MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment.

Proc Natl Acad Sci U S A 2009 Apr 16;106(14):5837-41. Epub 2009 Mar 16.

Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0812029106
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http://dx.doi.org/10.1073/pnas.0812029106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656554PMC
April 2009

Diverse TNFalpha-induced death pathways are enhanced by inhibition of NF-kappaB.

Int J Oncol 2007 Dec;31(6):1519-28

Department of Surgery, Section of General Surgery, University of Chicago Hospitals, Chicago, IL 60637, USA.

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December 2007

Interaction of amifostine and ionizing radiation on transcriptional patterns of apoptotic genes expressed in human microvascular endothelial cells (HMEC).

Int J Radiat Oncol Biol Phys 2004 Oct;60(2):553-63

Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2004.04.060DOI Listing
October 2004

STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells.

Proc Natl Acad Sci U S A 2004 Feb 30;101(6):1714-9. Epub 2004 Jan 30.

Department of Radiation and Cellular Oncology, University of Chicago, 910 East 58th Street, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1073/pnas.0308102100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC341831PMC
February 2004

Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine.

Int J Radiat Oncol Biol Phys 2002 May;53(1):180-9

Department of Radiation and Cellular Oncology, University of Chicago, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/s0360-3016(01)02820-6DOI Listing
May 2002