Publications by authors named "Niklas Mejhert"

42Publications

Glutamine metabolism in adipocytes: a epigenetic modulator of inflammation.

Adipocyte 2020 Dec;9(1):620-625

Department of Medicine (H7), Karolinska University Hospital , Stockholm, Sweden.

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http://dx.doi.org/10.1080/21623945.2020.1831825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553504PMC
December 2020

Age-Induced Reduction in Human Lipolysis: A Potential Role for Adipocyte Noradrenaline Degradation.

Cell Metab 2020 Jul 25;32(1):1-3. Epub 2020 Jun 25.

Department of Medicine (H7), Karolinska Institutet, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2020.06.007DOI Listing
July 2020

Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression.

Mol Cell 2020 03 4;77(6):1251-1264.e9. Epub 2020 Feb 4.

Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2020.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397554PMC
March 2020

MicroRNAs-361-5p and miR-574-5p associate with human adipose morphology and regulate EBF1 expression in white adipose tissue.

Mol Cell Endocrinol 2018 09 27;472:50-56. Epub 2017 Nov 27.

Lipid Laboratory, Department of Medicine Huddinge, Karolinska Institutet, SE-14186 Stockholm, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03037207173060
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http://dx.doi.org/10.1016/j.mce.2017.11.018DOI Listing
September 2018

Quantitative high-content/high-throughput microscopy analysis of lipid droplets in subject-specific adipogenesis models.

Cytometry A 2017 11 14;91(11):1068-1077. Epub 2017 Oct 14.

Department of Information Technology Division of Visual Information and Interaction and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1002/cyto.a.23265DOI Listing
November 2017

FANTOM5 CAGE profiles of human and mouse samples.

Authors:
Shuhei Noguchi Takahiro Arakawa Shiro Fukuda Masaaki Furuno Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Kaoru Kaida Ai Kaiho Mutsumi Kanamori-Katayama Tsugumi Kawashima Miki Kojima Atsutaka Kubosaki Ri-Ichiroh Manabe Mitsuyoshi Murata Sayaka Nagao-Sato Kenichi Nakazato Noriko Ninomiya Hiromi Nishiyori-Sueki Shohei Noma Eri Saijyo Akiko Saka Mizuho Sakai Christophe Simon Naoko Suzuki Michihira Tagami Shoko Watanabe Shigehiro Yoshida Peter Arner Richard A Axton Magda Babina J Kenneth Baillie Timothy C Barnett Anthony G Beckhouse Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher Ailsa J Carlisle Hans C Clevers Carrie A Davis Michael Detmar Taeko Dohi Albert S B Edge Matthias Edinger Anna Ehrlund Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Mary C Farach-Carson Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley M Forrester Rie Fujita Jun-Ichi Furusawa Teunis B Geijtenbeek Thomas Gingeras Daniel Goldowitz Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Yuki Hasegawa Meenhard Herlyn Peter Heutink Kelly J Hitchens David A Hume Tomokatsu Ikawa Yuri Ishizu Chieko Kai Hiroshi Kawamoto Yuki I Kawamura Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura Sarah Klein S Peter Klinken Alan J Knox Soichi Kojima Haruhiko Koseki Shigeo Koyasu Weonju Lee Andreas Lennartsson Alan Mackay-Sim Niklas Mejhert Yosuke Mizuno Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Kelly J Morris Hozumi Motohashi Christine L Mummery Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Tadasuke Nozaki Soichi Ogishima Naganari Ohkura Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Swati Pradhan-Bhatt Xian-Yang Qin Michael Rehli Patrizia Rizzu Sugata Roy Antti Sajantila Shimon Sakaguchi Hiroki Sato Hironori Satoh Suzana Savvi Alka Saxena Christian Schmidl Claudio Schneider Gundula G Schulze-Tanzil Anita Schwegmann Guojun Sheng Jay W Shin Daisuke Sugiyama Takaaki Sugiyama Kim M Summers Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Andru Tomoiu Hiroo Toyoda Marc van de Wetering Linda M van den Berg Roberto Verardo Dipti Vijayan Christine A Wells Louise N Winteringham Ernst Wolvetang Yoko Yamaguchi Masayuki Yamamoto Chiyo Yanagi-Mizuochi Misako Yoneda Yohei Yonekura Peter G Zhang Silvia Zucchelli Imad Abugessaisa Erik Arner Jayson Harshbarger Atsushi Kondo Timo Lassmann Marina Lizio Serkan Sahin Thierry Sengstag Jessica Severin Hisashi Shimoji Masanori Suzuki Harukazu Suzuki Jun Kawai Naoto Kondo Masayoshi Itoh Carsten O Daub Takeya Kasukawa Hideya Kawaji Piero Carninci Alistair R R Forrest Yoshihide Hayashizaki

Sci Data 2017 08 29;4:170112. Epub 2017 Aug 29.

RIKEN Omics Science Center, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1038/sdata.2017.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574368PMC
August 2017

Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis.

Cell Metab 2017 Aug;26(2):407-418.e3

Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195226PMC
August 2017

CD36 Is a Marker of Human Adipocyte Progenitors with Pronounced Adipogenic and Triglyceride Accumulation Potential.

Stem Cells 2017 07 18;35(7):1799-1814. Epub 2017 May 18.

Institut des Maladies Métaboliques et Cardiovasculaires, Team 1, INSERM and Université de Toulouse, Toulouse, Cedex, 4, France.

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http://dx.doi.org/10.1002/stem.2635DOI Listing
July 2017

Adipose and Circulating CCL18 Levels Associate With Metabolic Risk Factors in Women.

J Clin Endocrinol Metab 2016 Nov 26;101(11):4021-4029. Epub 2016 Jul 26.

Department of Medicine (H7) (D.E.H., P.P., J.B., I.D., J.L., J.A., A.E., A.K., N.M., D.P.A., P.A., M.R.), Karolinska Institutet, Stockholm, Sweden; Department of Biosciences and Nutrition (H.G.), Karolinska Institutet, Huddinge, Sweden; Department of Clinical Sciences (E.N.), Karolinska Institutet, Danderyd Hospital, Danderyd, Sweden.

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http://dx.doi.org/10.1210/jc.2016-2390DOI Listing
November 2016

MicroRNA-193b Controls Adiponectin Production in Human White Adipose Tissue.

J Clin Endocrinol Metab 2015 Aug 28;100(8):E1084-8. Epub 2015 May 28.

Lipid Laboratory, Department of Medicine Huddinge, Karolinska Institutet, SE-141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1210/jc.2015-1530DOI Listing
August 2015

Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue.

Proc Natl Acad Sci U S A 2015 Apr 23;112(14):4363-8. Epub 2015 Mar 23.

Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599;

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http://dx.doi.org/10.1073/pnas.1416412112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394244PMC
April 2015

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.

Authors:
Erik Arner Carsten O Daub Kristoffer Vitting-Seerup Robin Andersson Berit Lilje Finn Drabløs Andreas Lennartsson Michelle Rönnerblad Olga Hrydziuszko Morana Vitezic Tom C Freeman Ahmad M N Alhendi Peter Arner Richard Axton J Kenneth Baillie Anthony Beckhouse Beatrice Bodega James Briggs Frank Brombacher Margaret Davis Michael Detmar Anna Ehrlund Mitsuhiro Endoh Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley Forrester Daniel Goldowitz Reto Guler Thomas Ha Mitsuko Hara Meenhard Herlyn Tomokatsu Ikawa Chieko Kai Hiroshi Kawamoto Levon M Khachigian S Peter Klinken Soichi Kojima Haruhiko Koseki Sarah Klein Niklas Mejhert Ken Miyaguchi Yosuke Mizuno Mitsuru Morimoto Kelly J Morris Christine Mummery Yutaka Nakachi Soichi Ogishima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Xian-Yang Qin Sugata Roy Hiroki Sato Suzana Savvi Alka Saxena Anita Schwegmann Daisuke Sugiyama Rolf Swoboda Hiroshi Tanaka Andru Tomoiu Louise N Winteringham Ernst Wolvetang Chiyo Yanagi-Mizuochi Misako Yoneda Susan Zabierowski Peter Zhang Imad Abugessaisa Nicolas Bertin Alexander D Diehl Shiro Fukuda Masaaki Furuno Jayson Harshbarger Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Yuri Ishizu Masayoshi Itoh Tsugumi Kawashima Miki Kojima Naoto Kondo Marina Lizio Terrence F Meehan Christopher J Mungall Mitsuyoshi Murata Hiromi Nishiyori-Sueki Serkan Sahin Sayaka Nagao-Sato Jessica Severin Michiel J L de Hoon Jun Kawai Takeya Kasukawa Timo Lassmann Harukazu Suzuki Hideya Kawaji Kim M Summers Christine Wells David A Hume Alistair R R Forrest Albin Sandelin Piero Carninci Yoshihide Hayashizaki

Science 2015 Feb 12;347(6225):1010-4. Epub 2015 Feb 12.

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http://dx.doi.org/10.1126/science.1259418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681433PMC
February 2015

A promoter-level mammalian expression atlas.

Authors:
Alistair R R Forrest Hideya Kawaji Michael Rehli J Kenneth Baillie Michiel J L de Hoon Vanja Haberle Timo Lassmann Ivan V Kulakovskiy Marina Lizio Masayoshi Itoh Robin Andersson Christopher J Mungall Terrence F Meehan Sebastian Schmeier Nicolas Bertin Mette Jørgensen Emmanuel Dimont Erik Arner Christian Schmidl Ulf Schaefer Yulia A Medvedeva Charles Plessy Morana Vitezic Jessica Severin Colin A Semple Yuri Ishizu Robert S Young Margherita Francescatto Intikhab Alam Davide Albanese Gabriel M Altschuler Takahiro Arakawa John A C Archer Peter Arner Magda Babina Sarah Rennie Piotr J Balwierz Anthony G Beckhouse Swati Pradhan-Bhatt Judith A Blake Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher A Maxwell Burroughs Andrea Califano Carlo V Cannistraci Daniel Carbajo Yun Chen Marco Chierici Yari Ciani Hans C Clevers Emiliano Dalla Carrie A Davis Michael Detmar Alexander D Diehl Taeko Dohi Finn Drabløs Albert S B Edge Matthias Edinger Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Michela Fagiolini Lynsey Fairbairn Hai Fang Mary C Farach-Carson Geoffrey J Faulkner Alexander V Favorov Malcolm E Fisher Martin C Frith Rie Fujita Shiro Fukuda Cesare Furlanello Masaaki Furino Jun-ichi Furusawa Teunis B Geijtenbeek Andrew P Gibson Thomas Gingeras Daniel Goldowitz Julian Gough Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Matthias Harbers Jayson Harshbarger Akira Hasegawa Yuki Hasegawa Takehiro Hashimoto Meenhard Herlyn Kelly J Hitchens Shannan J Ho Sui Oliver M Hofmann Ilka Hoof Furni Hori Lukasz Huminiecki Kei Iida Tomokatsu Ikawa Boris R Jankovic Hui Jia Anagha Joshi Giuseppe Jurman Bogumil Kaczkowski Chieko Kai Kaoru Kaida Ai Kaiho Kazuhiro Kajiyama Mutsumi Kanamori-Katayama Artem S Kasianov Takeya Kasukawa Shintaro Katayama Sachi Kato Shuji Kawaguchi Hiroshi Kawamoto Yuki I Kawamura Tsugumi Kawashima Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura S Peter Klinken Alan J Knox Miki Kojima Soichi Kojima Naoto Kondo Haruhiko Koseki Shigeo Koyasu Sarah Krampitz Atsutaka Kubosaki Andrew T Kwon Jeroen F J Laros Weonju Lee Andreas Lennartsson Kang Li Berit Lilje Leonard Lipovich Alan Mackay-Sim Ri-ichiroh Manabe Jessica C Mar Benoit Marchand Anthony Mathelier Niklas Mejhert Alison Meynert Yosuke Mizuno David A de Lima Morais Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Efthymios Motakis Hozumi Motohashi Christine L Mummery Mitsuyoshi Murata Sayaka Nagao-Sato Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Kenichi Nakazato Erik van Nimwegen Noriko Ninomiya Hiromi Nishiyori Shohei Noma Shohei Noma Tadasuke Noazaki Soichi Ogishima Naganari Ohkura Hiroko Ohimiya Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Arnab Pain Robert Passier Margaret Patrikakis Helena Persson Silvano Piazza James G D Prendergast Owen J L Rackham Jordan A Ramilowski Mamoon Rashid Timothy Ravasi Patrizia Rizzu Marco Roncador Sugata Roy Morten B Rye Eri Saijyo Antti Sajantila Akiko Saka Shimon Sakaguchi Mizuho Sakai Hiroki Sato Suzana Savvi Alka Saxena Claudio Schneider Erik A Schultes Gundula G Schulze-Tanzil Anita Schwegmann Thierry Sengstag Guojun Sheng Hisashi Shimoji Yishai Shimoni Jay W Shin Christophe Simon Daisuke Sugiyama Takaai Sugiyama Masanori Suzuki Naoko Suzuki Rolf K Swoboda Peter A C 't Hoen Michihira Tagami Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Zuotian Tatum Mark Thompson Hiroo Toyodo Tetsuro Toyoda Elvind Valen Marc van de Wetering Linda M van den Berg Roberto Verado Dipti Vijayan Ilya E Vorontsov Wyeth W Wasserman Shoko Watanabe Christine A Wells Louise N Winteringham Ernst Wolvetang Emily J Wood Yoko Yamaguchi Masayuki Yamamoto Misako Yoneda Yohei Yonekura Shigehiro Yoshida Susan E Zabierowski Peter G Zhang Xiaobei Zhao Silvia Zucchelli Kim M Summers Harukazu Suzuki Carsten O Daub Jun Kawai Peter Heutink Winston Hide Tom C Freeman Boris Lenhard Vladimir B Bajic Martin S Taylor Vsevolod J Makeev Albin Sandelin David A Hume Piero Carninci Yoshihide Hayashizaki

Nature 2014 Mar;507(7493):462-70

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http://dx.doi.org/10.1038/nature13182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529748PMC
March 2014

Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms.

Cell 2014 Jan;156(1-2):343-58

Chair of Nutritional Medicine, Technische Universität München, Else Kröner-Fresenius-Center for Nutritional Medicine, 85350 Freising-Weihenstephan, Germany; Nutritional Medicine Unit, ZIEL-Research Center for Nutrition and Food Sciences, Technische Universität München, 85350 Freising-Weihenstephan, Germany; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany; Clinical Cooperation Group Nutrigenomics and Type 2 Diabetes, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany and Technische Universität München, 85350 Freising-Weihenstephan, Germany; Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg 85764, Germany. Electronic address:

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http://www.cell.com/cms/attachment/2021778258/2041667086/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S009286741301535
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http://dx.doi.org/10.1016/j.cell.2013.10.058DOI Listing
January 2014

Additive effects of microRNAs and transcription factors on CCL2 production in human white adipose tissue.

Diabetes 2014 Apr 30;63(4):1248-58. Epub 2013 Dec 30.

Department of Medicine, Huddinge, Lipid Laboratory, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.2337/db13-0702DOI Listing
April 2014

MicroRNA profiling links miR-378 to enhanced adipocyte lipolysis in human cancer cachexia.

Am J Physiol Endocrinol Metab 2014 Feb 10;306(3):E267-74. Epub 2013 Dec 10.

Lipid Laboratory, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden;

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http://dx.doi.org/10.1152/ajpendo.00249.2013DOI Listing
February 2014

Characterization of the Wnt inhibitors secreted frizzled-related proteins (SFRPs) in human adipose tissue.

J Clin Endocrinol Metab 2013 Mar 7;98(3):E503-8. Epub 2013 Feb 7.

Department of Medicine (H7), Karolinska Institutet, Karolinska University Hospital, Huddinge, 141 86, Stockholm, Sweden.

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http://dx.doi.org/10.1210/jc.2012-3416DOI Listing
March 2013

ITIH-5 expression in human adipose tissue is increased in obesity.

Obesity (Silver Spring) 2012 Apr 18;20(4):708-14. Epub 2011 Aug 18.

Sahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://doi.wiley.com/10.1038/oby.2011.268
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http://dx.doi.org/10.1038/oby.2011.268DOI Listing
April 2012

MTCH2 in human white adipose tissue and obesity.

J Clin Endocrinol Metab 2011 Oct 27;96(10):E1661-5. Epub 2011 Jul 27.

Department of Medicine, Huddinge, Lipid Laboratory, Novum, Karolinska Institutet, 141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1210/jc.2010-3050DOI Listing
October 2011

Differential effects of 1α,25-dihydroxycholecalciferol on MCP-1 and adiponectin production in human white adipocytes.

Eur J Nutr 2012 Apr 24;51(3):335-42. Epub 2011 Jun 24.

Department of Medicine Huddinge, Lipid Laboratory, Karolinska Institutet, NVS, Karolinska University Hospital Huddinge, 141 86, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00394-011-0218-zDOI Listing
April 2012

Twist1 in human white adipose tissue and obesity.

J Clin Endocrinol Metab 2011 Jan 13;96(1):133-41. Epub 2010 Oct 13.

Karolinska Institutet, Department of Medicine Huddinge, Lipid Laboratory, Stockholm, Sweden.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2010-0929DOI Listing
January 2011

Mapping of the fibroblast growth factors in human white adipose tissue.

J Clin Endocrinol Metab 2010 May 12;95(5):2451-7. Epub 2010 Mar 12.

Karolinska Institutet, Department of Medicine, Huddinge, Lipid Laboratory, Stockholm, Sweden.

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http://dx.doi.org/10.1210/jc.2009-2049DOI Listing
May 2010

Role of Receptor-Interacting Protein 140 in human fat cells.

BMC Endocr Disord 2010 Jan 29;10. Epub 2010 Jan 29.

Department of Medicine, Huddinge, Lipid Laboratory, NVS, Karolinska Institutet, SE- 141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1186/1472-6823-10-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825205PMC
January 2010

A possible inflammatory role of twist1 in human white adipocytes.

Diabetes 2010 Mar 10;59(3):564-71. Epub 2009 Dec 10.

Karolinska Institutet, Department of Medicine, Huddinge, Lipid Laboratory, NVS, Stockholm, Sweden.

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http://dx.doi.org/10.2337/db09-0997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828644PMC
March 2010